tell your doctor and pharmacist if you are allergic to etoposide, etoposide phosphate (Etopophos), any other medications, or any of the ingredients in etoposide or etoposide phosphate injection. (medlineplus.gov)
Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. (the-medical-dictionary.com)
Carboplatin7
The treatment combination of benmelstobart and anlotinib with Vepesid (etoposide) plus Paraplatin (carboplatin) as first-line treatment significantly improved survival outcomes for patients with extensive-stage small cell lung cancer (ES-SCLC), according to data from a phase 3 trial. (curetoday.com)
According to study protocol, treatment was switched to salvage chemotherapy with the standard etoposide/cisplatin regimen etoposide/carboplatin (Par-aplatin) in some cases if tumor regression of less than 25% was seen following the first course. (cancernetwork.com)
I. To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/ carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the event-free survival (EFS) of patients with newly diagnosed stage 4 diffuse anaplastic Wilms tumor (DAWT) as compared to historical controls. (clinicaltrials.gov)
To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the EFS of patients with standard-risk relapsed favorable histology Wilms tumor (SRrFHWT) as compared to historical controls. (clinicaltrials.gov)
I. To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the overall survival (OS) of patients with newly diagnosed stage 4 DAWT as compared to historical controls. (clinicaltrials.gov)
To establish EFS and OS for high-risk (HRrFHWT) and very high risk (VHRrFHWT) relapsed favorable histology Wilms tumor treated with ifosfamide/carboplatin/etoposide alternating with cyclophosphamide/ topotecan. (clinicaltrials.gov)
I. To describe renal toxicity of ifosfamide/carboplatin/etoposide in HRrFHWT and VHRrFHWT patients using conventional and novel biomarkers of renal toxicity (urine NGAL, cystatin C and Kim1) in the context of the chemotherapy regimens used on this study. (clinicaltrials.gov)
Combination chemotherapy with cisplatin and etoposide (cisplatin-etoposide [PE]) has long been the mainstay of treatment for small cell lung cancer (SCLC). (the-medical-dictionary.com)
Vepesid (etoposide) binds to and inhibits DNA topoisomerase II, resulting in accumulated DNA damage, inhibition of replication, and cell death (NCI Drug Dictionary). (jax.org)
Platinol2
The addition of cisplatin (Platinol) and oral etoposide (VePesid)to radiation therapy delays distant metastasis, thus increasingsurvival of patients with inoperable non-small-cell lung cancer,a comparison of RTOG 91-06 to RTOG 83-11 shows. (cancernetwork.com)
Median survival time was 11.7 months, which Dr. Negoro said 'favorably compares' to the 10- to 11-month survival time commonly reported for standard chemotherapy regimens, including cisplatin (Platinol)/etoposide (VePesid). (cancernetwork.com)
The 738 patients included in the trial with ES-SCLC did not previously receive systemic treatment (treatment for the entire body) and were randomly assigned to two groups: one with a placebo with Vepesid plus Paraplatin and one with benmelstobart and anlotinib with Vepesid plus Paraplatin. (curetoday.com)
Vepesid and Paraplatin are both chemotherapy drugs, often used to treat SCLC. (curetoday.com)
The benmelstobart combination also reduced the risk of death by 39%, versus placebo with Vepesid plus Paraplatin in this population. (curetoday.com)
Any-grade treatment-related side effects were experienced by 246 safety-evaluable patients who received the benmelstobart regimen, compared with 246 safety-evaluable patients who were given placebo and Vepesid plus Paraplatin. (curetoday.com)
Ethylidene1
Further chemical modifications led to the well-known thenylidene derivative VM-26 (teniposide, Vumon, discovered in October 1965, commercialized by Sandoz in 1976) and to the ethylidene derivative VP-16-213 (etoposide, Vepesid, discovered on 21 October 1966), which remains very clinically successful. (wikipedia.org)
Radiation1
Etoposide injection is used in combination with other medications to treat cancer of the testicles that has not improved or that has worsened after treatment with other medications or radiation therapy. (medlineplus.gov)
Injection3
Etoposide injection should be given only under the supervision of a doctor with experience in the use of chemotherapy medications. (medlineplus.gov)
Etoposide injection comes as a comes as a solution (liquid) or as a powder to be mixed with liquid to be slowly injected intravenously (into a vein) by a doctor or nurse in a medical facility. (medlineplus.gov)
Etoposide injection is also sometimes used to treat Hodgkin's lymphoma (Hodgkin's disease), non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection), and certain types of leukemia (cancer of the white blood cells), including acute myeloid leukemia (AML, ANLL) and acute lymphoblastic leukemia (ALL) in children. (medlineplus.gov)
Medications2
tell your doctor and pharmacist if you are allergic to etoposide, any other medications, or any of the ingredients in etoposide capsules. (navigatingcare.com)
Many other medications may also interact with etoposide, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (navigatingcare.com)
Enzyme4
apalutamide will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
enzalutamide will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
idelalisib will increase the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
ivosidenib will decrease the level or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
Etoposide is still considered a potent, well-tolerated combination partner in innumerable hematologic and solid tumor treatment schedules, including those for malignant lymphomas and lung cancer. (wikipedia.org)
Etoposide is also sometimes used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed). (navigatingcare.com)
etoposide is a cancer medicine that interferes with the growth and spread of cancer cells in the body. (exportersindia.com)
etoposide Effect of a structured, active, home based cancer your own friends feel the pain. (annamariadadomo.com)
Decrease1
Etoposide can cause a severe decrease in the number of blood cells in your bone marrow. (navigatingcare.com)
Oral3
etoposide decreases effects of adenovirus types 4 and 7 live, oral by pharmacodynamic antagonism. (medscape.com)
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Found1
Teniposide and etoposide were found by Stähelin to have a new mechanism of action: they blocked the entry of cells into mitosis (with arrest in late S or G2 phase), in contrast to SP-G and SP-I, which were spindle poisons. (wikipedia.org)
Results1
Instead Klose Training is low CBD content, while high THC options a a mixed format course 75 hours Dec 21 2018 etoposide RealSelf members say the cost 200 on average but each treatment session of Emsculpt costs about 1 000 and a series of four initial sessions results so you might end up paying more. (annamariadadomo.com)