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  • etiology
  • A multimodality strategy including both NPs and imaging studies appears to be the best strategy to define the cardiac dysfunction etiology and its severity as well as to identify patients with higher risk. (hindawi.com)
  • pulmonary
  • Right ventricular failure, defined as the inability to deliver sufficient blood flow through the pulmonary circulation at normal central venous pressure, is a common problem in the perioperative setting and is associated with an increased mortality. (biomedsearch.com)
  • Heart
  • This is a population-based study of the distribution of ventricular function parameters in 2,050 adult residents of Olmsted County, MN and, in collaboration with the Strong Heart study, in 1,522 adult Northern Plains American Indians. (clinicaltrials.gov)
  • The aim of this study is to evaluate left ventricular (LV) functions by tissue velocity imaging (TVI) and strain imaging (SI) in thalassemia patients without overt heart failure. (biomedsearch.com)
  • 001). CONCLUSION: Thalassemia patients have regional systolic dysfunction in the LV lateral and septal walls, even if they do not have overt heart failure. (biomedsearch.com)
  • Right heart strain (also right ventricular strain or RV strain) is a medical finding of right ventricular dysfunction where the heart muscle of the right ventricle (RV) is deformed. (wikipedia.org)
  • In those with heart failure due to left ventricular dysfunction, angiotensin converting enzyme inhibitors or angiotensin receptor blockers along with beta blockers are recommended. (wikipedia.org)
  • Aortic insufficiency (AI), also known as aortic regurgitation (AR), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. (wikipedia.org)
  • Catecholamines will increase the heart rate and increase the strength of ventricular contraction, directly increasing cardiac output. (wikipedia.org)
  • Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function in the presence of a diastolic dysfunction. (wikipedia.org)
  • Etiologically, four main causes are responsible for the development of heart failure in diabetic cardiomyopathy: microangiopathy and related endothelial dysfunction, autonomic neuropathy, metabolic alterations that include abnormal glucose use and increased fatty acid oxidation, generation and accumulation of free radicals, and alterations in ion homeostasis, especially calcium transients. (wikipedia.org)
  • prevalence
  • The DMHT group exhibited significantly higher systolic and diastolic blood pressure, higher prevalence of left ventricular hypertrophy, and more prescriptions for antihypertensive (ACE inhibitors, β-blockers, Ca antagonists, and diuretics) and lipid-lowering (statins and fibrates) drugs. (diabetesjournals.org)
  • However, available estimates of LVD prevalence are based on symptomatic patients, not on objectively measured ventricular function parameters. (clinicaltrials.gov)
  • overload
  • Reddy S, Zhao M, Fajardo G, Katnelson E, Spin JM, Bernstein D. Physiologic and molecular characterization of a murine model of right ventricular volume overload. (springer.com)
  • The volume overload, due to elevated pulse pressure and the systemic effects of neuroendocrine hormones causes left ventricular hypertrophy (LVH). (wikipedia.org)
  • The concentric hypertrophy is due to the increased left ventricular pressure overload associated with AI, while the eccentric hypertrophy is due to volume overload caused by the regurgitant fraction. (wikipedia.org)
  • tissue
  • Little NP is produced by ventricular tissue in normal adults, but it is present in ventricular tissue of fetuses and neonates and in hypertrophied ventricles. (ifcc.org)
  • Endothelial cells also are responsible for the production of E-selectin, which recruits lymphocytes into the tissue beneath the endothelium that subsequently release transforming growth factor beta, encouraging fibrosis and thus ventricular stiffening. (wikipedia.org)
  • cardiac output
  • It is thought that increased pressure, in concert with a pro-inflammatory state (insulin resistance, obesity), encourage ventricular stiffening and remodeling that lead to poor cardiac output seen in HFpEF. (wikipedia.org)
  • metabolic
  • Because PET technology is not widely available, and because on the basis of its expense and nonuniform reimbursement in this era of cost containment it is unlikely to be as available as SPECT in the future, the ability of SPECT imaging to assess regional metabolic activity in states of LV dysfunction is potentially of great interest. (ahajournals.org)