• Myocardial viability assessment is typically reserved for patients with coronary artery disease and significant left ventricular dysfunction. (onlinejacc.org)
  • In a 10-year follow up of survival in CASS (Coronary Artery Surgery Study), admittedly in an era when advances in medical therapeutics were only in their infancy, the presence of LV dysfunction represented an important discriminant for benefit from bypass graft surgery (1) . (onlinejacc.org)
  • 10 With the development of echocardiographic methods that provide a high yield of quantitative LV measurements, it has become possible to determine the prevalence and correlates of LV systolic dysfunction in population-based samples of hypertensive patients. (ahajournals.org)
  • Data from the MONICA (Monitoring of Trends and Determinations in Cardiovascular Disease) registry have shown that hypertension and obesity-both associated with type 2 diabetes and arterial stiffness-independently predicted left atrial (LA) enlargement, a sensitive indicator of an elevated LV preload ( 3 ). (diabetesjournals.org)
  • Because of the results of the DIAMOND study, some physicians use dofetilide in the suppression of atrial fibrillation in individuals with LV dysfunction, however use appears limited: After initially receiving marketing approval in Europe in 1999, Pfizer voluntarily withdrew this approval in 2004 for commercial reasons and it is not registered in other first world countries. (wikipedia.org)
  • Philadelphia, PA 11 June 2009 - The value and cost-effectiveness of screening for left ventricular (LV) dysfunction remains unclear, particularly since specific, evidence-based treatments are not available for the majority of patients with preserved systolic dysfunction, reports a study in the June issue of the Journal of Cardiac Failure ( http://www.onlinejcf.com ), published by Elsevier. (scienceblog.com)
  • Additionally, the Report highlights the frontrunners, the drivers and barriers for the Left Ventricular Dysfunction market, as well as treatment algorithm, current treatments & advancements are included.The chapters including marketed products highlights the advantages and disadvantages associated with therapies associated with Left Ventricular Dysfunction , providing an in-depth analysis of emerging therapies which will create an impact through their launch. (rnrmarketresearch.com)
  • This would be particularly true to the extent that imaging of preserved or enhanced metabolic activity in patients with LV dysfunction is more fundamentally sound or accurate for detecting myocardial viability than imaging cell membrane integrity with available SPECT agents such as 201 Tl or 99m Tc-based agents such as sestamibi or tetrofosmin. (ahajournals.org)
  • 1 Progressive pump failure and ventricular tachyarrhythmias are common causes of death in these patients despite optimal medical therapy. (bmj.com)
  • Because PET technology is not widely available, and because on the basis of its expense and nonuniform reimbursement in this era of cost containment it is unlikely to be as available as SPECT in the future, the ability of SPECT imaging to assess regional metabolic activity in states of LV dysfunction is potentially of great interest. (ahajournals.org)