• Giant cell arteritis (GCA) is characterized by intimal hyperplasia and luminal obstruction leading to ischemic manifestations involving extra-cranial branches of carotid arteries and aorta. (nih.gov)
  • sSDVG face limited success due to vascular wall thickening known as intimal hyperplasia (IH). (uwaterloo.ca)
  • Medial fibrosis and loss of muscularis with destruction of the internal elastic lamina and intimal hyperplasia was common. (neurology.org)
  • The development of neo-intimal hyperplasia and thrombosis in the distal anastomosis remains the main reason for occlusion in that region. (dundee.ac.uk)
  • The results suggest that spiral grafts are associated with advanced local haemodynamics that may protect endothelial function and thereby may prevent their outflow anastomosis from neo-intimal hyperplasia and thrombosis. (dundee.ac.uk)
  • Hydrogen-rich saline has been reported to prevent neointimal hyperplasia induced by carotid balloon injury. (molecularhydrogenstudies.com)
  • Daily injection of a hydrogen-rich saline solution (HRSS) in rats was employed to study the effect of hydrogen on balloon injury-induced neointimal hyperplasia and the neointima/media ratio was assessed. (molecularhydrogenstudies.com)
  • These results showed that hydrogen-rich saline was able to attenuate FBS-induced VSMC proliferation and neointimal hyperplasia by inhibiting ROS production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. (molecularhydrogenstudies.com)
  • Chen Y, Jiang J, Miao H, Chen X, Sun X, Li Y. Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. (molecularhydrogenstudies.com)
  • When bound, SBCV-030 locally prevents platelet binding to the exposed collagen and the subsequent platelet activation, which can lead to thrombus formation acutely and neointimal hyperplasia chronically. (news-medical.net)
  • Pulmonary inflammation, epithelial hyperplasia, and lymph node translocation after multi-walled carbon nanotube inhalation. (cdc.gov)
  • In lung, the principal changes were 1) inflammation centered around the bronchioloalveolar junction, 2) vasculitis, and 3) bronchiolar epithelial hypertrophy and hyperplasia. (cdc.gov)
  • Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling pathway. (uc.edu)
  • However, many disease-predisposing factors and/or contributing factors have been identified, including inflammation, endothelial cell dysfunction, aberrant vascular wall cell proliferation and mutations in the bone morphogenetic protein-receptor type 2 ( Bmpr2 ) gene [ 1 - 3 ]. (ersjournals.com)
  • Chronic neurodegenerative processes, vascular inflammation, occlusion and ectatic capillary changes lead to loss of outer retinal layers and formation of pseudolamellar macular holes with cysts or cavitations that can also be in the inner retinal layers. (aao.org)
  • Oxidative stress and inflammation in the vascular wall are essential mechanisms of atherosclerosis and vascular dysfunctions associated with risk factors such as metabolic diseases, aging, hypertension, etc. (frontiersin.org)
  • Mechanisms of pathogenesis of atherosclerosis are complex interplay between bloodstream cells and arterial wall components that leads to a chronic state of vascular oxidative stress and inflammation ( Hansson and Hermansson, 2011 ). (frontiersin.org)
  • In the past decades, unambiguous evidence has been provided that heightened oxidative stress and vascular wall inflammation are the key mechanisms for initiation and progression of atherosclerosis and vascular diseases associated with the risk factors ( Hansson and Hermansson, 2011 ). (frontiersin.org)
  • Portal hypertensive polyps (PHP) are a recent entity, described in cirrhotic patients with portal hypertension, portal venous obstruction or antral vascular ectasia. (isciii.es)
  • Chairmen Stephen Greenhalgh (London, UK) and Andrew Holden (Auckland, New Zealand) put together a far-reaching programme covering innovation and regulatory challenges, the future of EVAR devices, and sessions focussing on aortic, peripheral, venous and vascular access innovation-following the CX model. (cxsymposium.com)
  • Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere because of the terminal vascular network in this region, the frequent hand exposure to trauma and microtrauma, and the superficial location of the lesions. (springer.com)
  • Vascular lesions in the hand may be secondary to local pathology, a proximal source of emboli, or systemic diseases with vascular compromise. (springer.com)
  • The purpose of this article is to describe the state-of-the-art acquisition protocols and illustrate the different patterns of vascular lesions and perivascular tumours of the hand. (springer.com)
  • Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere. (springer.com)
  • Vascular lesions in the hand may be secondary to local pathology (e.g. tumour, malformation, trauma, iatrogenic cause, or drug injection), a proximal source of emboli (e.g. dissections or aneurysms), or systemic diseases with vascular compromise (e.g. rheumatic and vaso-occlusive diseases). (springer.com)
  • Clinical history and direct observation remain the best approach for diagnosis of vascular lesions in the hand. (springer.com)
  • In this article, we will review the relevant vascular anatomy, describe the state-of-the-art acquisition protocols, and illustrate the different patterns of vascular lesions of the hand in adults, while avoiding common diagnostic pitfalls. (springer.com)
  • These lesions are similar to hyperplastic polyps, but with subepithelial vascular alterations histological features. (isciii.es)
  • Sturge-Weber syndrome is a systemic condition commonly affecting oral cavity through vascular lesions, therefore, dentists' knowledge is extremely important to provide an adequate dental treatment without complications. (bvsalud.org)
  • According to the patient, the vascular lesions have been present since his childhood and the lesions' growth followed his growth. (bvsalud.org)
  • Currently, synthetic vascular grafts made using expanded polytetrafluoroethylene (ePTFE) or Dacron are commercially available as treatments to cardiovascular diseases. (uwaterloo.ca)
  • These synthetic vascular grafts have good patency, which is a measure used to determine the success of the grafts, and are actively used in more than 400,000 life-saving procedures in the United States alone. (uwaterloo.ca)
  • Synthetic small diameter vascular graft (sSDVG) is defined by synthetic vascular grafts with internal diameter less than 6mm. (uwaterloo.ca)
  • Polyurethane vascular grafts were modified with gelatin and collagen to enhance endothelial cell adhesion and were modified using heparin to reduce thrombogenesis. (uwaterloo.ca)
  • Likewise, poly(vinyl alcohol) (PVA) vascular grafts were developed in 2008. (uwaterloo.ca)
  • In this thesis, the roles crosslinking density and interlayer adhesion play in compliance and burst pressure of PVA vascular grafts were studied. (uwaterloo.ca)
  • By substantially reducing acute graft thrombosis within hours after implantation, the GORE® PROPATEN® Vascular Graft provides clinical benefits that standard expanded polytetrafluoroethylene (ePTFE) grafts do not. (goremedical.com)
  • Peripheral vascular grafts are used for the treatment of peripheral arterial disease and arteriovenous grafts for vascular access in end stage renal disease. (dundee.ac.uk)
  • In this work, spiral peripheral vascular and arteriovenous grafts were compared with conventional grafts using ultrasound and computational methods to identify their haemodynamic differences. (dundee.ac.uk)
  • Vascular-graft flow phantoms were developed to house the grafts in different surgical configurations. (dundee.ac.uk)
  • This study applied ultrasound and computational methods to vascular-graft phantoms in order to characterise the flow field induced by spiral and conventional peripheral vascular and arteriovenous grafts. (dundee.ac.uk)
  • In vitro effects of hydrogen on fetal bovine serum (FBS)-induced vascular smooth muscle cell (VSMC) proliferation were also investigated. (molecularhydrogenstudies.com)
  • Requena L, Sangueza OP. Cutaneous vascular proliferation. (medscape.com)
  • IH develop at the distal anastomosis of the graft and are due to over proliferation and abnormal migration of vascular smooth muscle cells (VSMC). (uwaterloo.ca)
  • Cutaneous biopsy revealed RAE characterized by the proliferation of epithelioid and spindle-shaped cells in superficial and middermis lining vascular channels, arranged in clusters, and sometimes displaying an intravascular growth pattern. (thedoctorsdoctor.com)
  • Histopathologically, it is characterized by a proliferation of endothelial cells within vascular lumina resulting in the obliteration of the involved vessels. (thedoctorsdoctor.com)
  • Both patients showed an arteriovenous 'steal' syndrome with distal ischemia, and it is possible that a local increase of vascular endothelial growth factor, as is the case in hypoxia situations, induces the endothelial proliferation. (thedoctorsdoctor.com)
  • Vascular occlusion, inflammatory changes and other neurodegenerative processes lead to loss of the outer nuclear layer, ellipsoid zone with later formation of cysts that can encompass all retinal layers. (aao.org)
  • Dr. Misra has received numerous grants to help fund research in the Vascular and Interventional Radiology Translational Research Lab through the years. (mayo.edu)
  • Case report and conclusion: The patient reported that he had presented a cutaneous vascular nevus on the face during childhood as well as epileptic crisis episodes. (bvsalud.org)
  • Pulmonary hypertension (PH) is characterised by widespread obstruction and obliteration of pulmonary arterioles, leading to a progressive elevation in pulmonary vascular resistance and subsequent right heart failure and death. (ersjournals.com)
  • Indeed, it is thought that RAE could be caused by ischemia secondary to vascular obstruction. (thedoctorsdoctor.com)
  • Pulmonary hypertension (PH) is a fatal disease with no treatment options, characterised by elevated pulmonary vascular resistanzce and secondary right ventricular failure. (ersjournals.com)
  • In this review, we discuss the potential influence of stromal vascular fraction from adipose tissue in the management of alopecia as well as its involvement in preclinical and clinical trials. (jcadonline.com)
  • With more than a decade of strong performance, this trusted vascular graft provides proven clinical and economic value. (goremedical.com)
  • In the past three decades, there have been no major advances in the field of hemodialysis vascular access, resulting in a huge unmet clinical need,' said Dr. Roy-Chaudhury. (news-medical.net)
  • The main clinical features of this syndrome are facial vascular cutaneous naevus, usually unilateral, which often follows the outline distribution of trigeminal nerve. (bvsalud.org)
  • The main significance of intravascular papillary endothelial hyperplasia is its clinical and histological resemblance to soft-tissue sarcoma and possible misinterpretation as such. (bvsalud.org)
  • We will investigate the effects of exenatide on vascular endothelial injury and nitrooxidative stress in hyperglycemia both in vivo and in vitro and explore the role of nitrooxidative stress in endothelium-protective action of exenatide. (hindawi.com)
  • In conclusion, this study demonstrates that exenatide treatment can alleviate the vascular endothelial injury, as well as attenuating the nitrooxidative stress in hyperglycemia, implying that the endothelium-protective effect of exenatide might be related to the reduction of nitrooxidative stress. (hindawi.com)
  • SBCV-030, which is modeled after the proteoglycan decorin, binds to collagen that is exposed when the vascular endothelium is denuded, an unavoidable consequence during any vascular intervention or surgery. (news-medical.net)
  • Overview of a histologic section from a tumor depicting dilated vascular spaces interspersed between collagen fibers and a more central accumulation of many complex vascular spaces. (medscape.com)
  • Collagen vascular disease must be excluded. (medscape.com)
  • [ 14 ] This accumulation of collagen and extracellular matrix that has not broken down is proposed to be the reason of gingival hyperplasia. (medscape.com)
  • Vascular graft is one of the examples. (uwaterloo.ca)
  • Compliance in vascular engineering is referring to the radial elasticity of the vascular graft or the blood vessel. (uwaterloo.ca)
  • For example, polyurethane is being studied as a potential compliant vascular graft. (uwaterloo.ca)
  • The compliance of PVA vascular graft developed by Chaouat et al. (uwaterloo.ca)
  • In part due to the sensitivity to fabrication condition, the consistency of PVA vascular graft suffered from person-to-person variation in fabrication process. (uwaterloo.ca)
  • Whether facilitating lower extremity revascularization or providing vascular access, the versatile GORE® PROPATEN® Vascular Graft is purposefully designed to improve outcomes and reduce reinterventions. (goremedical.com)
  • With more than 600,000 devices implanted over a span of more than 10 years ─ and over 2,000 limbs studies ─ the GORE® PROPATEN® Vascular Graft is a clinically proven prosthetic bypass graft solution, both for performance and for low cumulative cost of care. (goremedical.com)
  • A clinically proven prosthetic bypass graft solution, the GORE® PROPATEN® Vascular Graft also facilitates a low cumulative cost of care. (goremedical.com)
  • When your hemodialysis patients are at risk of fistula non-maturation, the GORE® PROPATEN® Vascular Graft can provide confidence and proven results. (goremedical.com)
  • The CBAS® Heparin Surface of a 3 mm diameter GORE® PROPATEN® Vascular Graft (top) remains free of thrombus, while the 3 mm diameter control ePTFE graft (bottom) is covered with thrombus in an acute two-hour in vivo canine carotid artery interposition model. (goremedical.com)
  • Weighted average of GORE® PROPATEN® Vascular Graft data. (goremedical.com)
  • Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. (goremedical.com)
  • The flow within the vascular-graft models was simulated with computed tomography based image-guided modelling for further understanding of secondary flow motions and comparison with the experimental results. (dundee.ac.uk)
  • If you've been told you are a candidate for prostate surgery , and would like to explore other options available using vascular radiology in Houston , schedule an appointment at Access Vascular Health. (accessvascularhealth.com)
  • A 55-year-old white female with a complex medical history including mixed connective tissue disease and peripheral vascular disease developed a group of red-purple papules on her proximal medial thigh that was followed, five months later, by the development of a large violaceous patch. (thedoctorsdoctor.com)
  • In traditional fashion, the CX Innovation Showcase did the job of raising important questions and challenges in the ever-developing and changing vascular and endovascular field. (cxsymposium.com)
  • Recent evidence has indicated that the vascular endothelial injury induced by hyperglycemia is associated with the enhanced nitrooxidative stress both in vivo and in vitro [ 3 - 6 ]. (hindawi.com)
  • Recent research provides emerging evidence supporting an essential role of increased activity of arginases including arginase-I and arginase-II in causing eNOS-uncoupling, which results in vascular oxidative stress and inflammatory responses, and ultimately leading to vascular diseases. (frontiersin.org)
  • This review article will summarize the most recent findings on the functional roles of arginases in vascular diseases and/or dysfunctions and the underlying mechanisms in relation to oxidative stress and inflammations. (frontiersin.org)
  • Moreover, regulatory mechanisms of arginases in the vasculature are reviewed and the future perspectives of targeting arginases as therapeutic options in vascular diseases are discussed. (frontiersin.org)
  • Therefore, elucidation of mechanisms underlying oxidative stress and inflammations in the vascular wall will have important impact in understanding atherosclerosis and vascular diseases associated with cardiovascular risk factors and will eventually lead to novel and effective therapeutic modalities. (frontiersin.org)
  • Nonetheless, because the vascular surgeon has always been primarily responsible for the diagnosis of extremity symptoms, it is not uncommon for patients with CRPS to report to a vascular surgeon because of extremity pain. (medscape.com)
  • In the four postmortem patients, the vascular pathology was similar, showing ectasia and aneurysmal dilatation confined to the large arteries of the circle of Willis. (neurology.org)
  • Brain computerized tomography (CT) with contrast showed minimal vascular ectasia of the circle of Willis( figure 1A ). (neurology.org)
  • Pathological study described gastric hyperplastic polyps with edema, vascular congestion and smooth muscle hyperplasia without dysplasia or adenomatous changes ( Fig. 2 ). (isciii.es)
  • In paper 1, I set out to summarize observational evidence and further determine the causal relationships between prediabetes and common vascular complications associated with T2D i.e., coronary artery disease (CAD), stroke and renal disease. (lu.se)
  • However, the vascular surgeon opted not to execute the interventions due to increased risk of hemorrhage. (bvsalud.org)
  • Because of the poor quality of the distal arteries, vascular surgery is rarely possible. (medscape.com)
  • 6. Appropriately sized and accessible target coronary arteries, with a minimum diameter of 2 mm and adequate vascular bed (without significant distal stenosis), as assessed by pre-operative cardiac angiography and verified by diameter gauging intraoperatively. (who.int)
  • A case of intravascular papillary endothelial hyperplasia clinically diagnosed and treated as a low-grade angiosarcoma, in a 60-year-old man, presenting with a mass in the left thigh, is reported. (bvsalud.org)
  • 2005 Mar-Apr;25(2B):1409-12.Intravascular papillary endothelial hyperplasia (Masson's hemangioma) presenting as a soft-tissue sarcoma. (bvsalud.org)
  • Another rare variant of reactive angioendotheliomatosis has been described in the lower extremities of patients with severe peripheral vascular atherosclerotic disease. (thedoctorsdoctor.com)
  • Evidence has been provided that activation of the vascular endothelial cells in the presence of the risk factors promotes oxidative stress and vascular inflammatory responses, leading to acceleration of atherosclerotic vascular disease. (frontiersin.org)
  • Here we review recent advances in the pathogenesis of GCA, with emphasis on the interactions between cells of the immune system and components of the vessel wall, including vascular smooth muscle cells and endothelial cells, leading to vascular remodeling. (nih.gov)
  • it is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. (medscape.com)
  • Focal nodular hyperplasia (FNH) is the second most common tumor of the liver, surpassed in prevalence only by hepatic hemangioma . (medscape.com)
  • Such high prevalence of DM, HTN and the age of onset of the disease can point toward a long-term vascular stress as the etiology for this entity. (aao.org)
  • Debate is ongoing regarding whether drug-induced gingival overgrowth is due to hyperplasia of the gingival epithelium or of submucosal connective tissue, and/or both. (medscape.com)
  • findings indicate severe dilation of blood vessel, necrosis of vascular connective tissues, wide spread vacuolar degeneration, edema and bile duct hyperplasia. (academicjournals.org)
  • Adipose tissue is a loose connective tissue composed of cells supported by an intracellular matrix as well as by vascular, lymphatic, and neural networks. (jcadonline.com)
  • If successful, Symic's innovative and pioneering approach to prevent vascular access stenosis could not only improve the quality of life and survival of ESRD patients, but also and reduce costs to the healthcare system. (news-medical.net)
  • Contact the prostate specialist in Houston and let Dr. Maneevese put her years of experience treating men for BPH and other vascular-related conditions to work for you. (accessvascularhealth.com)
  • In addition, it has also shown beneficial effects on both cardiac [ 11 - 13 ] and vascular endothelial functions [ 14 - 19 ]. (hindawi.com)
  • instead the vasoprotective nitric oxide (NO ⋅ ), plays a critical role in vascular dysfunction under various pathophysiological conditions and in aging. (frontiersin.org)
  • 8. History of cerebral vascular accident (CVA) or transient ischemic attacks (TIA) within the last 3 months. (who.int)
  • Hemodynamics have been shown to play an important role in the initiation and progress of intracranial aneurysms, and are considered well-related to vascular configuration. (ajnr.org)
  • The purpose of this study was to quantify the vascular geometry change due to intracranial stent placement and to discuss its potential effects on hemodynamics. (ajnr.org)
  • The current objectives were to quantify the vascular angle changes due to intracranial stent placement and discuss the stent-associated effects on hemodynamics. (ajnr.org)
  • Hydatidiform mole (HM) is an abnormal pregnancy, characterized by trophoblastic hyperplasia, vesicular swelling of the chorionic villi, and without a viable fetus. (au.dk)
  • There are several hypotheses about the mechanisms by which calcium antagonists induce gingival hyperplasia, but further investigation is still needed. (medscape.com)
  • Noninvasive vascular laboratory testing (see Laboratory Studies ), lumbosacral imaging, and neurologic evaluation all may contribute to distinguishing between these possibilities. (medscape.com)
  • Also known as encephalotrigeminal angiomatosis 1 , Sturge-Weber syndrome is a rare vascular neurocutaneous alteration presenting oral and systemic signals. (bvsalud.org)
  • With patency you can count on, you can give your patients reliable vascular access for the road ahead. (goremedical.com)