HomeostasisBlood VesselsEndothelium, VascularEndothelial CellsNitric Oxide Synthase Type IIIVascular DiseasesNitric OxideHuman Umbilical Vein Endothelial CellsCells, CulturedNeovascularization, PhysiologicSignal TransductionEpoprostenolMuscle, Smooth, VascularVasodilationAortaNitric Oxide SynthaseMice, KnockoutStress, MechanicalReactive Oxygen SpeciesAtherosclerosisMice, Inbred C57BLOxidative StressCell ProliferationGene Expression RegulationCell MovementCattleEnzyme ActivationTime FactorsIronCalciumGlucoseInsulin ResistanceEnergy MetabolismCation Transport ProteinsInsulinMice, TransgenicModels, BiologicalBlood GlucoseLipid MetabolismLiverMutationRNA, MessengerPhenotypeApoptosisTranscription FactorsCell DifferentiationMembrane ProteinsReverse Transcriptase Polymerase Chain ReactionMitochondriaEndoplasmic ReticulumIntestinesMolecular Sequence DataLeptinObesityCholesterolStress, PhysiologicalCell LineBiological TransportZincGene DeletionGlucose Tolerance TestHepcidinsBlotting, WesternHypothalamusEpidermisCopperReceptors, Cytoplasmic and NuclearCarrier ProteinsGene Expression