• Neither has the impact of folic acid supplementation as a secondary prophylactic treatment been definitely cleared since results of intervention studies are still lacking. (thieme-connect.de)
  • The aims of this study were to evaluate nutritional status for macronutrients and folic acid in members of a high-performance handball team, and determine the effect of a nutritional intervention with folic acid supplementation and education. (biomedcentral.com)
  • Nutritional, laboratory and physical activity variables were recorded at baseline (Week 0), after 2 months of dietary supplementation with 200 μg folic acid (50% of the recommended daily allowance) (Week 8) and after 2 months without supplementation (Week 16). (biomedcentral.com)
  • Folic acid supplementation may protect athletes against alterations that can lead to cardiovascular events related to exertion during competition. (biomedcentral.com)
  • To examine the effects of folic acid supplementation, with or without vitamin B12, on elderly healthy and demented people, in preventing cognitive impairment or retarding its progress. (unboundmedicine.com)
  • Folic acid supplementation continues to be actively debated in the medical literature, with conflicting findings regarding its significance. (medscape.com)
  • Folic acid supplementation clearly has significant public health implications. (medscape.com)
  • Initiate supplementation with oral folic acid and intramuscular vitamin B 12 to reduce the severity of hematologic and gastrointestinal toxicity of pemetrexed. (nih.gov)
  • Earlier research has shown that supplementation with B vitamins-specifically, vitamins B6, B12, and folic acid-lowers homocysteine levels(5), a risk marker for heart and cognitive health. (nutritionaloutlook.com)
  • The authors also reported that in 11 studies, in which the role of folic acid supplementation was examined, a normalization of the homocysteine levels was found when supplemental folic acid was consumed. (superiorsites3.com)
  • Folic acid deficiency contributes to aging brain processes and increased risk of Alzheimer's disease and vascular dementia. (clearviewtreatment.com)
  • High blood levels of homocysteine have been linked with the risk of arterial disease, dementia and Alzheimer's disease. (unboundmedicine.com)
  • There is therefore interest in whether dietary supplements of folic acid (an artificial chemical analogue of naturally occurring folates) can improve cognitive function of people at risk of cognitive decline associated with ageing or dementia, whether by affecting homocysteine metabolism or through other mechanisms. (unboundmedicine.com)
  • All double-blind placebo-controlled randomized trials, in which supplements of folic acid with or without vitamin B12 were compared with placebo for elderly healthy people or people with any type of dementia or cognitive impairment. (unboundmedicine.com)
  • One trial (VITAL 2003) studied the effects of a combination of vitamin B12 and folic acid on patients with mild to moderate cognitive impairment due to Alzheimer's disease or mixed dementia. (unboundmedicine.com)
  • Folic acid effect and people with mild to moderate cognitive decline or dementia: there were no statistically significant results in favour of folic acid with or without vitamin B12 on any measures of cognitive function. (unboundmedicine.com)
  • The aim of the study is to compare the basal homocysteine levels in patients with impairment of cognitive status, and in controls, to evaluate if the methionine loading test is able to identify any differences between patients with Alzheimers disease and patients with vascular dementia. (unicatt.it)
  • We enrolled 56 subjects, 20 with Alzheimers disease, 18 with vascular dementia, and 18 normal controls. (unicatt.it)
  • No significant differences were found between Alzheimers patients and vascular dementia patients. (unicatt.it)
  • Even if the methionine loading test revealed an abnormal homocysteine metabolism in demented patients, it didnt show any difference among patients with Alzheimers disease and vascular dementia. (unicatt.it)
  • In fact, research has shown that folic acid deficiency is linked to Alzheimer's disease and vascular dementia. (easyhealthoptions.com)
  • About the same time the unit opened, her husband Steve, then 53, began showing signs of progressive dementia, later diagnosed as Alzheimer's Disease. (anh-usa.org)
  • Leukoaraiosis at presentation and disease progression during follow-up in histologically confirmed cases of dementia. (ox.ac.uk)
  • Strikingly, researchers found a significant connection between these essays and occurrence of later-life dementia and/or Alzheimer's Disease. (weightcrafters.com)
  • Alzheimer disease (AD) is the most common progressive degenerative form of dementia, strongly associated with advancing age. (medscape.com)
  • The work of my small laboratory in the national program for prevention of mental retardation by early diagnosis of congenital hypothyroidism, and finally screening of early markers of initial stages of dementia en elderly people. (bvsalud.org)
  • Plasma homocysteine levels and mortality in patients with coronary artery disease. (thieme-connect.de)
  • The association between the biomarkers and the outcomes was studied using cause-specific hazard-models, adjusted for age, sex, history of coronary artery disease, NT-proBNP, CKD-EPI-derived eGFR and the urine albumin/creatinine ratio. (biomedcentral.com)
  • Subjects living with diabetes present an excess risk of coronary artery disease (CAD) and diabetic cardiomyopathy, which are the two main causes of heart failure (HF). (biomedcentral.com)
  • There is evidence that elevated homocysteine is associated with higher risk of coronary artery disease. (amedi.sk)
  • Elevated serum homocysteine levels have been strongly linked with an increased risk of cerebrovascular disease, coronary artery disease, myocardial infarction, and venous thrombosis. (methyl-life.com)
  • After reviewing 27 studies, they found that an increase of just five micromoles of homocysteine (five times its molecular weight in micrograms) per liter increased the risk of coronary artery disease by 60 percent. (superiorsites3.com)
  • They estimated that if individuals added just 200 micrograms of folate to their diets or if grains were fortified with folate, deaths from coronary artery disease could be reduced by 13,500 to 50,000 per year! (superiorsites3.com)
  • The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. (medscape.com)
  • Antidepressant effects have been recorded to be better when antidepressants are augmented with folic acid, or L-methyl folate, a more absorbable form of folic acid. (methyl-life.com)
  • 1] Eventually, two large trials in which women were randomly assigned to take folic acid or a placebo showed that getting too little folate increased a woman's chances of having a baby with spina bifida or anencephaly and that getting enough folate could greatly reduce the incidence of these birth defects. (harvard.edu)
  • Women who are pregnant or might become pregnant take folic acid to prevent miscarriage and "neural tube defects," birth defects such as spina bifida that occur when the fetus's spine and back do not close during development. (product-managers.com)
  • 4] Since the advent of mandatory folic acid fortification in 1998, neural tube birth defects have dropped by 28%, and studies have shown that far fewer people have low levels of folate in their blood. (harvard.edu)
  • The prevalence of folate deficiency has decreased since many countries in the western hemisphere introduced a mandatory folic acid food fortification program starting in the late 1990s. (medscape.com)
  • People who are at high risk of strokes and heart disease may greatly benefit by taking folic acid supplements. (encyclopedia.com)
  • To correct a folic acid deficiency, supplements are taken in addition to food. (encyclopedia.com)
  • The UL for adults for folic acid from fortified food or supplements (not including folate from food) is set at 1,000 mcg a day. (harvard.edu)
  • And some but not all observational studies, including the Nurses' Health Study, show lower risks of cardiovascular disease, stroke, and hypertension among people with higher intakes of folate from food, those who use multivitamin supplements, or those with higher levels of serum folate. (harvard.edu)
  • Several large randomized trials of B vitamin supplements to lower homocysteine levels and prevent heart disease and stroke failed to find a benefit. (harvard.edu)
  • The association of ADMA with abnormalities of lipid regulation suggested that supplements of free fatty acids might manipulate ADMA levels. (wikipedia.org)
  • Whilst approaches at modifying the latter with oral supplements of folic acid were strongly suggested, studies have shown this fails to give any clinical benefit and suggested that B vitamins might instead increase some cardiovascular risks. (wikipedia.org)
  • Taking vitamin B6 supplements by mouth or eating large amounts of vitamin B6 in the diet doesn't seem to reduce the risk for Alzheimer disease. (medlineplus.gov)
  • For this reason trials of folic acid supplements may involve simultaneous administration of vitamin B12. (unboundmedicine.com)
  • There is growing evidence that nutritional supplements-vitamins, minerals, amino acids, fatty acid nutrients, herbal and botanical products, and various other natural compounds like coenzyme Q10 and alpha lipoic acid-have specific health benefits, in addition to those provided by the right diet, daily exercise, reducing stress, and getting a good night's sleep. (tahomaclinicblog.com)
  • A recent study conducted in China sought to evaluate whether low-dose vitamin B supplements could reduce the risk of heart and vascular diseases. (nutritionaloutlook.com)
  • But even if you're already dealing with a neurodegenerative disease, recent research conducted by researchers at McMaster University found that a targeted combination of nutritional supplements can not only prevent the loss of brain cells that's characteristic of neurodegenerative diseases - it can reverse it. (easyhealthoptions.com)
  • However, little is known on the status of use of folic acid and vitamin supplements among people with mental disorders. (product-managers.com)
  • This study examined the prevalence and the likelihood of use of folic acid or vitamin supplements among adults with depression and anxiety in comparison to those without … Studies have shown that people who suffer heart attacks have lower amounts of both dietary and plasma folic acid. (product-managers.com)
  • In 1998, the U.S. Food and Drug Administration ( FDA ) required food manufacturers to add folic acid to enriched bread and grain products to boost intake and to help prevent neural tube defects (NTD). (encyclopedia.com)
  • Folic acid deficiency during pregnancy increases the risk for neural tube defects including cleft palate, spina bifida, and brain damage. (healthyplace.com)
  • Many neural tube defects (such as spina bifida) are believed to be preventable if women of childbearing age supplement their diets with folic acid. (healthyplace.com)
  • A recent study found that the prevalence of neural tube defects in the United States has decreased by 19% since the FDA authorized the fortification of grains with folic acid. (healthyplace.com)
  • This phenomenon has been extensively researched in relation to the regular dietary consumption of folic acid and the prevention of neural tube defects during embryogenesis in humans. (ppdictionary.com)
  • It also contains the protective nutrients alpha lipoic acid, NAC, inositol and choline to complement the neural, cognitive, cardiovascular, liver and skin health properties of this diverse profile. (healthywithjodi.com)
  • RÉSUMÉ Cet article présente la tendance du spina bifida et d'autres malformations du tube neural à Oman, après la mise en place au niveau national de la supplémentation en acide folique chez les femmes enceintes en 1990, et l'enrichissement de la farine de blé en fer et en acide folique en 1996. (who.int)
  • Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study. (thieme-connect.de)
  • ABSTRACT Hyperhomocysteinaemia is considered as an important independent risk factor for atherosclerosis and thrombotic disease. (who.int)
  • Rheumatoid arthritis (RA) is a chronic inflammatory systemic disease predisposing to atherosclerosis and high cardiovascular risk ( 1 , 2 ). (spandidos-publications.com)
  • Hyperhomocysteinemia is associated with significant risk of stroke, narrowing of the carotid artery due to atherosclerosis and peripheral vascular disease. (amedi.sk)
  • The dramatic decline in cardiovascular mortality in the United States since 1950 may possibly be attributable in part to voluntary fortification of the food supply with vitamin B-6 and folic acid. (drcalapai.com)
  • Fortification of the US food supply with folic acid in 1998, as mandated by the US Food and Drug Administration, was associated with a further decline in mortality from vascular disease, presumably because of increased blood folate and decreased blood homocysteine in the population. (drcalapai.com)
  • In most areas China does not fortify any food with folic acid, and therefore the population may be generally deficient. (sciencebasedmedicine.org)
  • As mentioned, pregnant women who are deficient in folic acid are more likely to have children with birth defects. (healthyplace.com)
  • Research studies have shown that a deficient supply of dietary folic acid may be a risk factor for several human diseases, including neonatal malformations, Down syndrome, Alzheimer's disease, cardiovascular disorders and cancer. (methyl-life.com)
  • Hematinic deficiency: Up to 20% of patients are deficient of iron, folic acid (folate), or vitamin B. (medscape.com)
  • Hyperhomocysteinemia: an independent risk factor for vascular disease. (thieme-connect.de)
  • Numerous clinical and epidemiologic studies have established elevated blood homocysteine as a potent independent risk factor for vascular disease in the general population. (drcalapai.com)
  • Daily consumption of 1,000 mcg of folic acid for three or more months has resulted in improved cervical cells upon repeat Pap smears. (encyclopedia.com)
  • Clinically, many naturopathic and other doctors recommend the use of vitamin B complex 50 mg per day with additional folic acid 800 to 1,000 mcg per day to try to prevent miscarriage (also known as spontaneous abortion). (healthyplace.com)
  • Elevated levels of this substance appear to be linked to certain chronic conditions such as heart disease and, possibly, depression and Alzheimer's Disease . (healthyplace.com)
  • In their most recent study, researchers studied mice who had lost nearly half of their brain cells - essentially mice with a neurological situation similar to what occurs in Alzheimer's disease. (easyhealthoptions.com)
  • She discovered that with Alzheimer's disease, certain brain cells may have difficulty utilizing glucose (made from the carbohydrates we eat), the brain's principal source of energy. (anh-usa.org)
  • In fact, it is estimated that someone is diagnosed with Alzheimer's Disease in the United States every 68 seconds. (weightcrafters.com)
  • While the specific physiological reasons for this connection were not a part of this particular study, other research has found that incidents of Alzheimer's Disease often correlate with Heart Disease. (weightcrafters.com)
  • Vitamin B9, also called folic acid or folate, is one of eight water-soluble B vitamins. (healthyplace.com)
  • Folic acid or folate is a water-soluble vitamin of the B complex which plays a critical role in cell division and the formation of new cells - two main processes that are vital during prenatal development and the maturation of undifferentiated cells. (ppdictionary.com)
  • Folic acid is a water soluble B vitamin, which means it cannot … You can consider getting your folic acid levels checked with a blood test by your doctor. (product-managers.com)
  • Folic acid, together with vitamins B 6 and B 12 , helps break down homocysteine, and may help reverse the problems associated with elevated levels. (encyclopedia.com)
  • 7-12] But linking higher homocysteine levels-and lower folate levels-with heart disease risk does not necessarily mean that lowering homocysteine by taking folate and other B vitamins will lower risk. (harvard.edu)
  • is a meta-analysis of randomized controlled trials looking at a variety of vitamins, both multivitamins and specific vitamins, and their relationship to cardiovascular disease, stroke, and all-cause mortality. (sciencebasedmedicine.org)
  • Vitamin B9 works closely with vitamins B6 and B12 as well as the nutrients betaine and S-adenosylmethionine (SAMe) to control blood levels of the amino acid homocysteine. (healthyplace.com)
  • Hyperhomocysteinemia can by lowered simply by adequate taking of folic acid, vitamins B6 and B12. (amedi.sk)
  • Recently published trials support the benefits of supplementing with key vitamins for diseases such as arthritis, multiple sclerosis, heart disease, and hearing deficits. (nutritionaloutlook.com)
  • Research has shown that B vitamins can reduce brain shrinkage by up to 90 percent by suppressing the amino acid homocysteine, which has been linked to the development of Alzheimer's, among other diseases. (easyhealthoptions.com)
  • It is a metabolic product of metabolism, which depends on the activity of certain specific enzymes as well as at least two, and probably three vitamins, Vitamin B6, folic acid, and Vitamin B12. (superiorsites3.com)
  • Dietary deficiency of vitamin B-6 and folic acid and absorptive deficiency of vitamin B-12, which result from traditional food processing or abnormal absorption of B vitamins, are important factors in causing elevations in blood homocysteine. (drcalapai.com)
  • In addition to a full range of daily vitamins and minerals, Ortho Multi™ Women's 40+ supplies free radical fighting ingredients such as CoQ10, Alpha Lipoic Acid, Lutein and Lycopene to help fight the ravages of aging. (healthywithjodi.com)
  • Folic acid (also known as vitamin B9) is actually an extremely important component of a healthy diet and thus of the supply of our organism. (product-managers.com)
  • It is also used for heart disease, premenstrual syndrome (PMS), depression, morning sickness, Alzheimer disease, menstrual cramps, diabetes, and many other conditions, but there is no good scientific evidence to support many of these other uses. (medlineplus.gov)
  • Taken in the correct doses these nutraceuticals can help prevent cancer, heart disease, depression, neurodegenerative diseases, and prevent loss of hearing and loss of vision from macular degeneration and cataracts. (tahomaclinicblog.com)
  • In terms of depression, folic acid deficiency may increase the risk of depression and reduce the action of antidepressants. (methyl-life.com)
  • The hope is that such intervention might not only improve endothelial function but also reduce clinical symptoms of overt cardiovascular disease. (wikipedia.org)
  • For example, hyperglycemia caused by diabetes results in vascular endothelial damage as well as increased blood viscosity, which in turn decreases blood flow. (optometrytimes.com)
  • Studies have shown that patients with cardiovascular disease are characterized by impaired endothelial function (EF). (ox.ac.uk)
  • Alcoholism, irritable bowel syndrome, and celiac disease contribute to deficiency of this important nutrient. (healthyplace.com)
  • You may be at a greater risk of folate deficiency if you are pregnant, or have Chrohn's disease or celiac disease. (product-managers.com)
  • Malabsorption in gastrointestinal disorders: About 3% of patients experience these disorders, particularly celiac disease (gluten-sensitive enteropathy) but, occasionally, Crohn disease, pernicious anemia, and dermatitis herpetiformis. (medscape.com)
  • Moreover, this is also a potential treatment for Parkinson's disease, Huntington's disease, multiple sclerosis and amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), drug-resistant epilepsy, brittle type I diabetes, and type II (insulin-resistant) diabetes. (anh-usa.org)
  • Many people think of diseases like Alzheimer's, Parkinson's and other dementias that typically afflict the elderly as "inevitable" - but research has shown quite the opposite. (weightcrafters.com)
  • Cod liver oil - Since it contains DHA, a type of omega-3 fatty acid, cod liver oil is a serious boon to your brain health. (easyhealthoptions.com)
  • Our product range includes a wide range of cefixime 200 mg lactic acid bacillus tablet, rabeprazole 20mg + domperidone 10 mg, aceclofenac 100mg + paracetamol 325mg + serratiopeptidase 15mg tab, methylcobalamin alpha lipoic acid thiamine folic acid pyridoxine, omega 3 fatty acid tablets and betahistine 16 mg. (simiklifesciences.com)
  • Description: Calcitriol+Calcium Carbonate+Omega-3 fatty acid+Methylcobalamin+Folic Acid+Boron are used in the treatment of nutritional deficiencies. (simiklifesciences.com)
  • There was no effect on plasma lipids or uric acid, but there was a lower glucose and insulin peak concentration after consumption of the FVPD compared with the sugar-matched control. (cambridge.org)
  • People with cancer, chronic illness, and neurodegenerative diseases should take sufficient vitamin D to attain a level of 80 ng/ml (which requires 8,000-10,000 IU/day). (tahomaclinicblog.com)
  • Neurodegenerative diseases are some of the scariest diseases out there. (easyhealthoptions.com)
  • This article explores the mechanisms and manifestations behind folate deficiency, as well as its ramifications with regard to health and disease at large. (medscape.com)
  • Folic acid, or folate, deficiency is a serious condition that needs to be treated rapidly. (product-managers.com)
  • Folic acid is also used for other conditions commonly associated with folate deficiency, including ulcerative colitis, liver disease, alcoholism, and kidneydialysis. (product-managers.com)
  • Adequate intake of folic acid is vital for the prevention of several types of birth defects , particularly NTDs. (encyclopedia.com)
  • Data will be used for research to further define nutrient requirements as well as optimal levels for disease prevention and health promotion. (cdc.gov)
  • The survey was conducted by the Ambulatory Care Statistics Branch of the National Center for Health Statistics, Centers for Disease Control and Prevention. (cdc.gov)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Prevention, early detection, and covering preventive services, older adults without supple- management of diseases can improve our nation's health mental coverage were approximately 10% less likely to use and reduce health care costs (3). (cdc.gov)
  • Yet health il ness and disability, they rarely cover important pre- care insurance benefits have historical y been designed ventive benefits, and they may not fol ow evidence-based to address the treatment of diseases, not their prevention recommendations (7). (cdc.gov)
  • Without doubt treatment with corticosteroids is very effective for SLE, but in longstanding disease complications such as infections and osteoporosis are worrying. (bmj.com)
  • Cardiovascular and cerebrovascular diseases are the leading cause of morbidity and mortality worldwide ( 5 ). (spandidos-publications.com)
  • Most of the available approaches include pharmaceutical agents routinely used such as statins, angiotensin converting enzyme inhibitors, antioxidants, L-arginine, insulin sensitizers or others still under investigation such as tetrahydrobiopterin or folic acid (folate). (ox.ac.uk)
  • This is why sufficient daily intake of folic acid is necessary. (encyclopedia.com)
  • Studies have repeatedly shown that individuals with higher regular intake were significantly less likely not only to have Alzheimers, but also heart disease as well. (weightcrafters.com)
  • A major cause of homocysteinemia is insufficient intake of vitamin B6, vitamin B12, and folic acid, all of which are also necessary for HCY metabolism. (cdc.gov)
  • Analysis of an archival case of homocystinuria from 1933 and a case of cobalamin C disease from 1968 led to the conclusion that homocysteine causes vascular disease by a direct effect of the amino acid on arterial cells and tissues. (drcalapai.com)
  • Bound to cysteine in place of sulfur and called the "21st amino acid," selenocysteine is the active site in some 35 proteins. (tahomaclinicblog.com)
  • Homocysteine is a homologue of the amino acid cysteine which is used by the body to help manufacture proteins and carry out cellular metabolism. (ppdictionary.com)
  • 2007). In the latter mechanism, homocysteine is condensed with the amino acid serine in a reaction catalyzed by the enzyme cystathionine-β-synthase to form cystathionine, which in turn, is reduced to cysteine and α-ketobutyrate by the enzyme cystathionine lyase. (ppdictionary.com)
  • Homocysteine (HCY), a risk factor for cardiovascular and other diseases, is converted to cysteine by PLP-dependent transsulfuration enzymes. (cdc.gov)
  • There is a risk that if folic acid is given to people who have undiagnosed deficiency of vitamin B12 it may lead to neurological damage. (unboundmedicine.com)
  • Folic acid will correct the anaemia of vitamin B12 deficiency and so delay diagnosis but will not prevent progression to neurological damage. (unboundmedicine.com)
  • The positive effects on microalbuminuia and delaying the progression to end stage renal disease. (biomedcentral.com)
  • Relation of serum homocysteine and lipoprotein(a) concentrations to atherosclerotic disease in a prospective Finnish population based study. (thieme-connect.de)
  • A reduction in PLP availability appears to primarily affect kynureninase activity, limiting NAD production and leading to higher concentrations of kynurenine, 3-hydroxykynurenine, and xanthurenic acid in blood and urine ( Figure 2 ) (9) . (oregonstate.edu)
  • The homocysteine theory of arteriosclerosis attributes one of the underlying causes of vascular disease to elevation of blood homocysteine concentrations as the result of dietary, genetic, metabolic, hormonal, or toxic factors. (drcalapai.com)
  • Research indicates that low serum vitamin D levels are associated with multiple sclerosis (MS) and that low vitamin D levels can affect the severity of the disease. (nutritionaloutlook.com)
  • An elevated blood level of the amino acid homocysteine has been identified as a risk factor for some of these diseases. (encyclopedia.com)
  • More recently degrees of folate inadequacy, not severe enough to produce anaemia, have been found to be associated with high blood levels of the amino acid homocysteine. (unboundmedicine.com)
  • Folic acid works together with vitamin B 12 and vitamin C to metabolize protein in the body. (encyclopedia.com)
  • Folic acid also works closely together with vitamin B12 to regulate the formation of red blood cells and to help iron function properly in the body. (healthyplace.com)
  • The role of homocysteine as a risk factor for cardiovascular disease is suggested to be mediated by homocysteine down-regulating production of DDAH in the body. (wikipedia.org)
  • Plasma homocysteine as a risk factor for cardiovascular disease: The European Concerted Action Project. (thieme-connect.de)
  • The definition of normohomocyst- a risk factor for cardiovascular disease Data collection einaemia was Hcy 15 µmol/L and (CVD) [1,2]. (who.int)
  • alterations in this nutrient are a risk factor for cardiovascular disease. (biomedcentral.com)
  • Total cholesterol is an independent risk factor for cardiovascular disease. (ecopolitan.com)
  • With raised levels of ADMA seemingly to be associated with adverse human health consequences for cardiovascular disease, metabolic diseases, and also a wide range of diseases of the elderly, the possible lowering of ADMA levels may have important therapeutic effects. (wikipedia.org)
  • The metabolic syndrome involves a pattern of multiple pathological features, i.e. several diseases and risk factors that come together and are usually linked. (myinsomniafix.com)
  • Homocysteine is actually a by product of certain normal metabolic amino acid breakdown and processing. (ecopolitan.com)
  • There have even been cases where neurological disorders where caused solely by a severe folic acid deficiency and were completely reversible through supplement therapy. (easyhealthoptions.com)
  • In regards to vascular disease, polymorphisms can increase your risk of vascular disease and all of the aforementioned disorders. (methyl-life.com)
  • One such consideration is to avoid overlooking choroidal circulations-while these disorders are usually lumped under "retinal vascular diseases," the choroidal circulations also play an imperative role in both normal retinal function and its vascular disease state. (optometrytimes.com)
  • Taking vitamin B6 by mouth, usually with folic acid, is effective for treating high homocysteine levels in the blood. (medlineplus.gov)
  • Alcohol use can lower levels of folic acid. (clearviewtreatment.com)
  • Some researchers have even speculated that there is a connection between high levels of this amino acid and cervical cancer, but the results of studies regarding this have been inconclusive. (healthyplace.com)
  • High levels of circulating homocysteine are associated with an increased risk of cardiovascular disease . (oregonstate.edu)
  • If you've experienced elevated homocysteine levels in the past, you may want to check your Methyl folate blood for a polymorph Orphism or gene defect that decreases your ability to metabolize folic acid. (methyl-life.com)
  • Homocysteine is a sulfer-containing amino acid, and it is normal to have some of this in your system - however elevated levels of homocysteine is toxic to the DNA of brain cells, and can contribute to their premature death. (weightcrafters.com)
  • 91 Additionally, low folic acid levels are associated with an increased risk of colorectal dysplasia or cancer in IBD patients 92-94 as well as the general population. (product-managers.com)
  • Folic acid tablets are used to restore folate levels. (product-managers.com)