Marfan SyndromeVascular DiseasesPeripheral Vascular DiseasesAortic AneurysmMicrofilament ProteinsEctopia LentisAneurysm, DissectingLoeys-Dietz SyndromeDilatation, PathologicCollagen DiseasesAortic Aneurysm, ThoracicMicrofibrilsAortaAortic DiseasesHomocysteineRisk FactorsElastinArteriosclerosisAtherosclerosisMuscle, Smooth, VascularEndothelium, VascularElastic TissueMitral Valve ProlapseDiabetic AngiopathiesAorta, ThoracicCardiovascular DiseasesChromosomes, Human, Pair 15Cerebrovascular DisordersAmputationFunnel ChestPedigreeVascular Surgical ProceduresBlood Vessel Prosthesis ImplantationTime FactorsHyperhomocysteinemiaIschemiaBlood VesselsMyocytes, Smooth MuscleCells, CulturedFollow-Up StudiesTreatment OutcomeHypertension, PulmonaryAortographySpinal Cord Vascular DiseasesRetrospective StudiesTunica MediaArterial Occlusive DiseasesEndothelial CellsAortic RuptureIntermittent ClaudicationAorta, AbdominalPhenotype