• Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. (jove.com)
  • These play important functions in a broad range of physiological and pathological processes," Diao explained. (uc.edu)
  • Ephrins, also known as ephrin ligands, and Eph receptors (Ephs), which are RTKs, are key regulators of physiological and pathological processes involved in development and disease, such as cellular motility, cell repulsion, and cell adhesion [ 4 ]. (hindawi.com)
  • Mechanical stress can modulate physiological processes at the molecular, cellular and systemic level. (springer.com)
  • The topics are discussed in a form of review articles, written by leading researchers who study the mechanosensitivity process at the molecular, cellular, tissue and whole organ levels. (springer.com)
  • We are also studying what the molecular and physiological processes that these drought-tolerant QTL provide to get a better insight into this complex trait. (irri.org)
  • Dr. Sieck has developed an extensive array of state-of-the-art physiological, molecular and biomedical engineering techniques to explore cell signaling pathways. (mayo.edu)
  • By definition, comparative physiology is broad, spanning a variety of animal taxa occurring in diverse environmental settings, and studied at many levels of biological organization (from molecular physiology to physiological ecology). (scienceblogs.com)
  • We are using a variety of technical approaches for the study of SCN pacemaker function ranging from the molecular to the behavioral levels in Syrian hamsters and mice. (kent.edu)
  • The Preclinical Nuclear Medicine Facility comprising of radiotracer techniques such as Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT), which provide unique means for high-sensitivity studies of physiological function and molecular biodistribution. (lu.se)
  • The Clinical 1.5/3 Tesla Magnetic Resonance Imaging Facility comprises a variety of tools ranging from high-resolution anatomical structure visualization to functional studies and even molecular-level description of metabolic events in the cell. (lu.se)
  • Copper ions bind to biomolecules (e.g., peptides and proteins) playing an essential role in many biological and physiological pathways in the human body. (mdpi.com)
  • It orchestrates a variety of physiological processes via numerous signaling pathways. (bvsalud.org)
  • It is inferred that the metabolic processes may be improved through the auto-regulation of the neurohumoral regulatory system, as the result some biochemical reactions and consequently the aging process may be slowed down, whereas certain functions may be activated to maintain youthful vigor and exploit potential energy. (qigonginstitute.org)
  • such shifts in metabolic processing may underestimate or obscure differences in kinetics. (cdc.gov)
  • Health effects of the plant are … due to a non-specific influence on the production … of regulatory body hormones that affect both anabolic and metabolic processes via an 'adaptogenic' mechanism. (losethebackpain.com)
  • However, if this mechanism is blocked, not only are cellular recycling processes diminished, the animal's lifespan is also reduced. (medindia.net)
  • Nitric oxide (NO) is an important signaling molecule that regulates a diverse range of physiological and cellular processes in many tissues. (intechopen.com)
  • The AAA ATPase p97 is an essential protein involved in numerous cellular processes and plays a key role in multiple aspects of protein homeostasis. (uni-wuerzburg.de)
  • Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes in cancer [ 3 ]. (hindawi.com)
  • Several Ephrin A (EPHA/EFNA) family members are overexpressed or downregulated in a variety of tumors, suggesting that they act as oncogenes or as tumor suppressors according to the cellular context [ 9 ]. (hindawi.com)
  • You will gain hands-on experience in planning and conducting laboratory experiments that address fundamental cellular mechanisms underlying physiological and disease processes. (lu.se)
  • Through a series of 35 total physiological, biochemical, and morphological tests the isolate was able to be presumptively identified to the genus level. (ukessays.com)
  • Se- lective receptor inactivation is an early change fol- lowing exposure to certain neurotoxins, e.g., failure of the generator potential, followed by loss of the axon filopod processes in Pacinian corpuscles, are early physiological and morphological alterations following acrylamide intoxication (4, 5). (cdc.gov)
  • Thus, acting on ion channels in the plasma membrane, mechanical stress can elicit a multitude of biochemical processes - both transient and long-lasting - inside a cell. (springer.com)
  • Due to its significant role in regulating a variety of physiological responses, p97 has emerged as a potential therapeutic target. (uni-wuerzburg.de)
  • it also allowed the development of complex physiological responses. (nobelprize.org)
  • Processed by a variety of proteases linked to inflammation, it activates the G-protein coupled receptor chemokine-like receptor 1 (CMKLR1) and induces chemotaxis in natural killer cells, macrophages, and immature dendritic cells. (nih.gov)
  • They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis. (bvsalud.org)
  • We found that C3 regulates process of autophagy and cell survival upon stress and now we aim to investigate what role C3 may play in β-cell physiology and islet inflammation. (lu.se)
  • One aim of the research is to study how environmental information is integrated by the circadian clock to regulate the timing of daily behavioral, physiological and neuroendocrine rhythms. (kent.edu)
  • The acute effects measured were both physiological and behavioral. (cdc.gov)
  • This activity results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and changes in emotional and cognitive processes. (rcsb.org)
  • We defined work-related hypervigilance as an extreme attentiveness to and assessment of the environment for potential danger that goes along with cognitive and physiological arousal. (cdc.gov)
  • Several physiological changes in the speech production process in old age have been documented, yet studies of cognitive changes are few and inconclusive. (lu.se)
  • Although aging is associated with many physiological and cognitive changes, such as muscle atrophy (Volpi et al. (lu.se)
  • 2002). If speech fluency is affected by age, it might entail that certain aspects of the cognitive speech production process change throughout the lifespan. (lu.se)
  • First of all, disfluencies, defined as interferences in the otherwise fluent flow of speech, arise from errors or delays in the cognitive speech production process and are consequently relevant to general theories of language production (Fraundorf et al. (lu.se)
  • Due to the presence of the limbic system, the temporal lobe contributes to a variety of autonomic states and physiological processes, such as sexual arousal, anxiety levels, and hunger. (medicinenet.com)
  • The tests were often the paper-and-pencil psychological tests and generally lacked sensitivity to discern early, subtle changes in attention, arousal, information processing, and memory performance functions. (cdc.gov)
  • Rice variety 'IR64' was sown monthly 15-times in a row in two locations in Senegal. (plos.org)
  • IRRI is working towards introducing drought tolerance into popular high-yielding rice varieties including IR64, Swarna, and Vandna. (irri.org)
  • Flood-tolerant varieties that have been released and are now being planted include Swarna Sub1 in India, Samba Mahsuri in Bangladesh, IR64-Sub1 in the Philippines, and Ciherang Sub1 in Indonesia and Nepal. (irri.org)
  • Cell motility is a complex process that requires post-translational regulation of a wide variety of proteins. (nature.com)
  • Cannabinoid receptors are utilized endogenously by the body through the endocannabinoid system, which includes a group of lipid proteins, enzymes, and receptors that are involved in many physiological processes. (rcsb.org)
  • If there are too few chaperones in the cell, then newly-made proteins may fold incorrectly and interrupt other processes. (elifesciences.org)
  • However, what physiological and evolutionary processes allow for the enormous variety of flower colours, shapes, and visual patterns found in desiertos floridos? (helsinkitimes.fi)
  • These two species' anatomical and physiological comparisons show that P. arabica carries unique features that support stem gas exchange and high-gross photosynthetic rates via stem photosynthetic capabilities (SPC). (frontiersin.org)
  • This review summarizes BACE properties, describes BACE translation dysregulation in AD, and discusses BACE physiological functions in sodium current, synaptic transmission, myelination, and schizophrenia. (jneurosci.org)
  • Their dysregulation can lead to a variety of human diseases. (uc.edu)
  • Researchers have developed a number of potassium ion (K+) probes to detect fluctuating K+ concentrations during a variety of biological processes. (phys.org)
  • Using predicted physiological concentrations of nitric oxide (NO), superoxide and hydrogen peroxide (H2O2) on low numbers of CFU of B. bronchiseptica, all redox active species displayed dose-dependent antimicrobial activity. (bio5.org)
  • In physiological concentrations, androgens have no specific effects in women. (cdc.gov)
  • Here, the current understanding of chemerin processing, signaling and physiological function has been summarized, focusing on the regulation of its activity, its different receptors and its controversially discussed role in diseases. (nih.gov)
  • These cells secrete a variety of signals, such as the cytokine Interleukin-1 (IL-1), and also possess membrane receptors for IL-1. (jove.com)
  • The interaction between ligands and receptors via bidirectional signaling and its involvement in cancer biology are mediated by complex processes [ 7 , 8 ]. (hindawi.com)
  • It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. (rcsb.org)
  • The softgel capsule filling machine improves the delivery of medications and supplements to physiological targets, while increasing operational efficiency during the manufacturing process. (packworld.com)
  • This week Idiap's speech group will be presenting five papers at Interspeech 2020, the largest conference for automatic speech processing. (idiap.ch)
  • The plant tissue is reported to relieve a variety of ailments considered to result from physiological stress on the body. (losethebackpain.com)
  • While there is a rich history of anecdotal accounts of the benefits of marijuana and a long tradition of marijuana being used for a variety of ailments, the scientific literature in support of medicinal uses of marijuana is less substantial. (medscape.com)
  • The underlying processes are mediated by the regulatory microRNA molecule mir-71. (medindia.net)
  • This molecule regulates the genetic program of olfactory neurons and, afterwards, degradation processes in the digestive tract. (medindia.net)
  • Dr. Sieck examines basic mechanisms underlying muscle fiber atrophy and weakness under a variety of conditions and diseases. (mayo.edu)
  • This breadth allows comparative physiology to (a) understand basic physiological processes and (b) identify novel mechanisms used by animals to solve specific physiological challenges. (scienceblogs.com)
  • This mechanism is central for the proper processing of odor signals and mediates adjustments in the intestinal cells. (medindia.net)
  • Cancerous cells secrete a variety of self-sustaining growth signals that act as autocrine mediators and control cell division rates. (jove.com)
  • Environmental signals that ultimately arise from the spin of the earth set the internal clock through the process of entrainment. (umass.edu)
  • Students will explore hunger, satiety, and mindful eating to discover how our eating habits are impacted by our awareness to physiological signals of hunger or fullness. (agclassroom.org)
  • Study establishes a connection between an increased risk of depression and the consumption of ultra-processed foods. (medindia.net)
  • it projects to most key brain regions and modulates numerous physiological functions. (hindawi.com)
  • Katrina Miranda, PhD, claims nitric oxide (NO), which is synthesized in the body via enzymatic oxidation of L-arginine, is critical to numerous physiological functions, but also can contribute to the severity of diseases such as cancer or pathophysiological conditions such as stroke. (bio5.org)
  • Today, investigators prefer automated tests that are designed to assess these functions in a variety of ways, thus enabling neurobehavioral testing to be more capable of detecting subclinical acute effects. (cdc.gov)
  • IRRI is developing rice varieties that can withstand conditions forecast to become more frequent and intense with climate change. (irri.org)
  • Along with improved crop management, proper use of technology through extension work and the support of national institutions, these improved varieties or "climate change-ready rice" are showing substantial, positive impacts in the lives of poor farmers. (irri.org)
  • The business unit Greenhouse Horticulture can make an important contribution to this process by utilising modern greenhouses and climate chambers, physiological knowledge, automated measurements, and the use of models to analyse data. (wur.nl)
  • Damage-regulated autophagy modulator 2(DRAM2) is associated with autophagy processes. (cancerindex.org)
  • Wageningen University & Research applies knowledge of plant physiology to the practice of horticulture and develops crop growth models and plant monitoring processes to enable precise control of cultivation. (wur.nl)
  • During its domestication process, many of its natural traits were lost. (frontiersin.org)
  • It helps breeders incorporate specific desirable traits into new varieties with more accuracy and speed. (irri.org)
  • In particular, he focuses on regenerative processes that can be enhanced to mitigate a variety of acute and chronic disease conditions. (mayo.edu)
  • Scabby blight" of the Jordanolo variety of almond is a hard and woody, ashen-gray or brownish scale growth on the kernel skin. (fda.gov)
  • Consciousness is a construct that encompasses a variety of physiological processes related to the experience of awareness and the acquisition of knowledge in human beings. (bvsalud.org)
  • A master pacemaker in the suprachiasmatic nucleus of the hypothalamus (SCN) is required not only for rhythmicity of sleep and wakefulness, but also to insure optimal physiological function as incompatible events are scheduled to occur at different phases. (umass.edu)
  • While both CBD and THC are used for medicinal purposes, they have different receptor activity, function, and physiological effects. (rcsb.org)
  • Mechanosensitivity is common to a wide variety of cells in many different organisms ranging from bacteria to mammals. (springer.com)
  • From a pharmacological perspective, Cannabis' (and CBD's) diverse receptor profile explains its potential application for such a wide variety of medical conditions. (rcsb.org)
  • The climac- governorate (urban, rural and informal/ teric, or climacterium, is used to refer to unplanned areas) were recruited to share the wide variety of physiological changes in focus group discussions (FGDs). (who.int)
  • The Preclinical 9.4 Tesla Magnetic Resonance Imaging Facility offers a modern and robust imaging MRI system (9.4T) and staff with many years of practical experience in a wide variety of MR-applications. (lu.se)
  • Several features of the somatosensory system render regions of it vulnerable to a wide variety of toxicants. (cdc.gov)
  • Healthy eating is a term used to describe the consumption of a variety of foods that provide essential nutrients for maintaining physiological processes, health, wellness, and adequate energy. (agclassroom.org)
  • While most of the high yielding rice varieties suffer heavy losses due to floods, several landraces with tolerance to different forms of flooding have evolved across Asia. (irri.org)
  • For example, deepwater rice varieties are able to elongate rapidly to survive while most of the high-yielding modern varieties cannot elongate enough. (irri.org)
  • Scientists were able to isolate the SUB1A gene, derived from an Indian rice variety, and identify the genetic control of submergence tolerance. (irri.org)
  • Therefore, the accurate detection of physiological NO concentration is crucial to the understanding of NO signaling and its biological role. (intechopen.com)
  • On the other hand, if too many chaperones are present they may slow down the protein folding process. (elifesciences.org)
  • This ubiquitous nature of bacteria allows them to grow in vast variety of places such as beneath the ground soil, on desk chairs, on door handles, in lakes, and in/on countless of other surfaces. (ukessays.com)
  • Principles of Pediatric Environmental Health: Why Do a Child's Age and Developmental Stage Affect Physiological Susceptibility to Toxic Substances? (cdc.gov)
  • Traditional, Complementary and Integrative Medicines (TCIM) are a group of medical systems and therapeutic methods, health practices and products that, in general, are not considered part of conventional medicine (Western or allopathic), although they have different origins and therapeutic proposals among them, they all share a complex, intercultural and comprehensive view of the health-disease process, which allows characterizing them as a broad contemporary field of knowledge construction, in constant evolution. (bvsalud.org)
  • Since sleep problems are linked to the development of of alcoholism, it is important to understand the neural processes that contribute to ethanol-associated effects in the circadian clock. (kent.edu)
  • In the new guidelines, the approach to dose-re- incidence have seldom taken into account key events sponse assessment for a particular agent is based on integral to the carcinogenic process which precede the conclusion reached as to its mode of carcino- the development of tumours, even though these genic action. (cdc.gov)
  • In spite of the evaluated studies have cited the effectiveness of laser therapy such as tissue repair, anti-inflammatory and analgesic, variety of analysis models and diversity of dosimetry leaves a gap on their true efficacy. (bvsalud.org)
  • This plays an important role for the recycling of cells and during the aging process. (medindia.net)
  • To date, RUNX2 has been involved in diverse physiological processes, including osteogenic differentiation of mesenchymal stem/stromal cells, chondrocyte hypertrophy, immunomodulation, vascular invasion and endothelial cell migration via modulating a variety of signaling cascades (e.g. (spandidos-publications.com)
  • You can eat a variety of foods, including less healthy favorites. (medlineplus.gov)
  • It helps the brain identify objects, recognize language, and plays an important role in visual and auditory processing. (medicinenet.com)
  • The neural elements of the clock are confined to the suprachiasmatic nuclei (SCN) of the anterior hypothalamus, which offers an anatomically-discrete model for studying integrative processes regulating specific aspects of circadian rhythms. (kent.edu)
  • Good Clinical Research Practice (GCP) is a process that incorporates established ethical and scientifi c quality standards for the design, conduct, recording and reporting of clinical research involving the participation of human subjects. (who.int)
  • Physiological effects of using cannabis make sense in the context of its receptor activity as the hippocampus and amygdala are primarily involved with regulation of memory, fear, and emotion. (rcsb.org)
  • or physiological or as a description of key events and processes starting toxic effects that affect cell proliferation. (cdc.gov)
  • This shows that the psychological activity of controlling one's thoughts has an actual physiological effect. (qigonginstitute.org)
  • The present report highlights these features and, furthermore, suggests that analysis of these regions is invaluable in studying the three most common varieties of toxic neuropathy: toxic distal axonopathy, toxic myelinopathy and toxic sensory neuronopathy. (cdc.gov)
  • The structure and discipline of the government environment teaches you that process is important whether you are framing a competitive or a sole-source scenario," he says. (cio.com)
  • The conduct of clinical research is complex and this complexity is compounded by the need to involve a number of dif- ferent individuals with a variety of expertise, all of who must perform their tasks skil ful y and effi ciently. (who.int)
  • The smell of food induces a variety of physiological processes in our body. (medindia.net)
  • The SCN receives a privileged retinal input and communicates with other brain areas and the rest of the body through a variety of projections. (umass.edu)
  • The unit can run a variety of shapes and capsule sizes. (packworld.com)