AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
EhrlichiaEhrlichia chaffeensisEhrlichia canisEhrlichiosisEhrlichia ruminantiumRickettsiaceaeRickettsiaceae InfectionsAnaplasmaDog DiseasesTicksAnaplasmataceaeIxodesHeartwater DiseaseDogsTick-Borne DiseasesHorse DiseasesTick InfestationsAnaplasmosisPolymerase Chain ReactionGenetic VariationAntibodies, BacterialMolecular Sequence DataRNA, Ribosomal, 16SArachnid VectorsNeorickettsiaHorsesDNA, BacterialAnaplasma phagocytophilumAntigens, BacterialArthropod VectorsRickettsiaSequence Analysis, DNAIxodidaeBase SequenceAnaplasmataceae InfectionsDeerBabesiaPhylogenyRickettsieaeRickettsia rickettsiiAnaplasma centraleAmino Acid SequenceRhipicephalus sanguineusFluorescent Antibody Technique, IndirectDoxycyclineBartonellaSerologic TestsChaperoninsBacterial ProteinsPolymorphism, Single NucleotideDisease ReservoirsChromosome WalkingDNA, RibosomalGranulocytesGenotypeBacterial Outer Membrane ProteinsAnaplasma marginaleSeroepidemiologic StudiesOxytetracyclineArgasGenetic Predisposition to DiseaseAlternative SplicingSpecies SpecificityNymph
AnaplasmaChaffeensisCanisMurisEwingiiBartonellaRickettsiaMinasensisRuminantiumBacteria that are transmittedPathogensInfection2001IxodesMonocytesGeneSpeciesGenesEmergenceStrainAgentMultipleStructureHostRhode Island and ConnecticutPhagocytophilaEquiTicksIntracellularGenus2016AmplificationPathogenEhrlichiaeLymeNationalRisk
Anaplasma7
Chaffeensis4
  • citation needed] The following species have been effectively and validly published: Ehrlichia canis (Donatien and Lestoquard 1935) Moshkovski 1945 (Approved Lists 1980) Ehrlichia chaffeensis Anderson et al. (wikipedia.org)
  • Interestingly, the 5' structure of this A. marginale msp2 locus is conserved in the omp1 gene locus of Ehrlichia chaffeensis and p30 gene locus of E. canis despite marked divergence between genera in the structure of the 3' region of the loci. (oregonstate.edu)
  • audit_author.name 'Seattle Structural Genomics Center for Infectious Disease (SSGCID)' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'Structure of thymidylate kinase from Ehrlichia chaffeensis. (rcsb.org)
  • Human monocytic ehrlichiosis (HME) is an emerging life-threatening tick-borne disease caused by the obligate intracellular bacterium Ehrlichia chaffeensis . (scientificarchives.com)
Canis1
  • Ehrlichia canis infects monocytes and is the causative agent of canine ehrlichiosis, which is a serious and potentially fatal disease of dogs. (vin.com)
Muris2
  • 2016 Ehrlichia muris Wen et al. (wikipedia.org)
  • Recent discoveries of emerging pathogens such as Borrelia mayonii and Ehrlichia muris add to the complexity of properly diagnosing and treating tickborne diseases. (cdc.gov)
Ewingii1
Bartonella1
  • Basic local alignment search tool (BLAST) analysis revealed the presence of known pathogens of cattle, such as Bartonella, Ehrlichia minasensis, and Dermatophilus congolensis. (bvsalud.org)
Rickettsia1
Minasensis1
Ruminantium2
Bacteria that are transmitted1
  • Ehrlichia is a genus of Rickettsiales bacteria that are transmitted to vertebrates by ticks. (wikipedia.org)
Pathogens1
  • Ehrlichia species are obligately intracellular pathogens and are transported between cells through the host cell filopodia during initial stages of infection, whereas in the final stages of infection, the pathogen ruptures the host cell membrane. (wikipedia.org)
Infection1
  • Bjoersdorff A, Brouqui P, Eliasson I, Massung RF, Wittesjo B, Berglund J. Serological evidence of Ehrlichia infection in Swedish Lyme borreliosis patients. (unt.edu)
20011
  • 2001 Ehrlichia sennetsu (Misao and Kobayashi 1956) Ristic and Huxsoll 1984 The following species have been published, but are not valid according to the Bacteriological Code: "Ehrlichia japonica" Lin et al. (wikipedia.org)
Ixodes2
  • A new species of Ehrlichia was discovered inside the deer tick Ixodes scapularis. (wikipedia.org)
  • Phylogenetic analysis of the 16S rRNA gene sequence of the bacterium found in R. norvegicus rats and Ixodes ovatus ticks in Japan revealed that the organism represents a novel clade in the family Anaplasmataceae, which includes the Schotti variant found in Ixodes ricinus ticks in the Netherlands and the Ehrlichia-like Rattus strain found in R. norvegicus rats from China. (uibk.ac.at)
Monocytes1
  • Macrophages and monocytes are the major target cells for Ehrlichia , although this bacterium can infect other cell types such as hepatocytes and endothelial cells [ 4 ]. (scientificarchives.com)
Gene4
  • These copies and fragments of membrane proteins can then recombine, through a process called gene conversion, resulting in a new gene variant. (wikipedia.org)
  • T variant of the A4GALT gene. (bvsalud.org)
  • T variant of the A4GALT gene probably underlay the p phenotype in this individual. (bvsalud.org)
  • Every person has two copies of the ApoE gene and there are six possible variants. (chewbook.com)
Species2
  • The species is known as Ehrlichia Wisconsin HM543746. (wikipedia.org)
  • 2021 "Ehrlichia ovina" Moshkovski 1945 "Ehrlichia platys" French and Harvey 1983 The following species have been published as candidatus species: "Candidatus Ehrlichia corsicanum" Cicculli et al. (wikipedia.org)
Genes2
  • 2003 The Ehrlichia genome contains many different variants of genes that encode outer membrane proteins, which have gone through intense modification over long periods of time. (wikipedia.org)
  • Because sporadic breast cancer may be influenced by a number of lifestyle and environmental factors as well as common low-risk variants in a number of genes, several models have been developed in an attempt to quantify individualized breast cancer risk. (myselfie.co.za)
Emergence2
  • The report highlights that given the continued emergence of new variants of concern which may have enhanced transmissibility and pathogenicity variants of concern from animals should remain the subject of ongoing research. (rcvsknowledge.org)
  • Furlan JPR, Castillo DF, Stehling EG, Sellera FP, Lincopan N. The emergence of tet(X) variants highlight challenges for the global genomic surveillance of tigecycline resistance [Internet]. (usp.br)
Strain1
Agent2
  • DNA-sequences from variant 1 and the human granulocytic ehrlichiosis (HGE) agent were also detected. (biomedcentral.com)
  • The data show that dogs can be naturally infected concurrently with A. phagocytophilum variant 1, variant 4 and the HGE agent. (biomedcentral.com)
Multiple2
  • DNA from A. phagocytophilum variant 4 (of 16S rRNA) was found in multiple and sequential samples. (biomedcentral.com)
  • Alternate splicing results in multiple transcript variants. (nih.gov)
Structure1
  • In contrast, mutations in opag3 seem to underlie purifying (negative) selection reflecting pressure to retain protein structure, in marked contrast to the highly antigenically variant MSP2. (oregonstate.edu)
Host1
Rhode Island and Connecticut1
  • Primers were used to amplify a 561-bp region of the 16S rRNA gene of Ehrlichia phagocytophila from Ixodes scapularis ticks and small mammals collected in Rhode Island and Connecticut. (nih.gov)
Phagocytophila7
  • Rhode Island samples from I. scapularis ticks, white-footed mice, and chipmunks contained E. phagocytophila variants as well as EP-ha. (medscape.com)
  • However, if the 1997 Rhode Island data, which were skewed by an unusually large number of variants, are removed from the calculations, the percentage of E. phagocytophila -positive ticks (adults and nymphs) was significantly higher in Bridgeport (13.3%) than in Rhode Island (8.2%) (p=0.03). (medscape.com)
  • In contrast, the sequences from 92 of 123 E. phagocytophila-positive Rhode Island samples collected from 1996 through 1999 included several variants differing by 1-2 nucleotides from that in the agent infecting humans. (nih.gov)
  • While 11.9% of 67 E. phagocytophila-positive ticks collected during 1997 in Rhode Island harbored ehrlichiae with sequences identical to that of the human agent, 79.1% had a variant sequence not previously described. (nih.gov)
  • Another ehrlichia found in nature, which is closely related to E. phagocytophila but apparently does not cause human disease, is the white-tailed deer agent ( 15 ). (cdc.gov)
  • Although the HGE agent is now considered a member of the species E. phagocytophila , hereafter we will designate the isolates responsible for human disease as E. phagocytophila -human agent (EP-ha) to differentiate them from the 16S rRNA sequence variants we describe in this report. (cdc.gov)
  • Agent of HGE" is a still unnamed Ehrlichia species related to E. phagocytophila and E. equi. (wesign4u.com)
Equi1
  • Although both the white-tailed deer agent and the E. equi /CA human sequence variant ( Table 2 ) are amplified by the PCR assay used in this study, neither agent has been detected in potential rodent reservoir populations in Connecticut or Rhode Island. (medscape.com)
Ticks6
  • In contrast to ticks and rodents from the Bridgeport area, nymphal ticks collected in 1997 from Bluff Point in southeastern Connecticut contained a nearly equal distribution of EP-ha (5 [55.6%] of 9 positives) and variant 1 (4 [44.4%] of 9 positives) ehrlichiae. (medscape.com)
  • Fifteen (16.3%) ticks showed sequences corresponding to variant 1. (medscape.com)
  • A variant that differed by 2 bp from the sequence of the HGE agent was reported in white-tailed deer in Maryland and Wisconsin and in Ixodes scapularis ticks collected in Rhode Island ( 13 , 14 ). (cdc.gov)
  • Ehrlichia is a genus of Rickettsiales bacteria that are transmitted to vertebrates by ticks. (wikipedia.org)
  • Ehrlichia are small obligately intracellular bacteria in the order Rickettsiales that are transmitted by ticks and associated with emerging life-threatening human zoonoses. (wnt-pathway.com)
  • We identified a single tick-specific amino acid variant in the viral glycoprotein region that dramatically reduces its fusion activity in human cells, providing evidence that a glycoprotein precursor variant, present in ticks, has severely impaired function in human cells. (elifesciences.org)
Intracellular1
  • Members of the genus Ehrlichia are obligate, intracellular bacteria in the order Rickettsiales. (cdc.gov)
Genus2
  • The genus Ehrlichia is named after German microbiologist Paul Ehrlich. (wikipedia.org)
  • There are two cell types of this genus: large cell variants (LCVs) and small cell variants (SCVs). (kenyon.edu)
20163
Amplification1
Pathogen1
  • New technologies for exploring host-pathogen interactions have yielded recent advances in understanding the molecular interactions between Ehrlichia and the eukaryotic host cell and identified new targets AZD5582 purchase for therapeutic and vaccine development, including those that target pathogen virulence mechanisms or disrupt the processes associated with ehrlichial effector proteins. (wnt-pathway.com)
Ehrlichiae1
  • The low incidence of human ehrlichiosis in Rhode Island may in part result from interference by these variant ehrlichiae with maintenance and transmission of the true agent of human disease. (nih.gov)
Lyme1
  • Dr. McManus is very concerned by the lack of diagnostic tools for the thousands of Australian patients who show symptoms of tick borne diseases but never test positive for Lyme disease because they have variant forms of relapsing fever. (lymedisease.org)
National1
  • Probable remark in our idea in the double-well trapped Bose-Einstein condensate will be mentioned.National variants feelings identification functionality have usually been recently reported, by which time period of live in a foreign lifestyle looks like it's an essential element. (hedgehogsignal.com)
Risk1
  • MBL deficiency (Mannose Binding Lectin Deficiency) is probably the explanation for this association, as impaired MBL variants are associated with higher risk of cryptosporidium enteritis. (phoenixrising.me)