AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and Processes
Choroid DiseasesChoroid PlexusUveitis, AnteriorChoroidUveitis, PosteriorUveitis, IntermediateChoroid Plexus NeoplasmsPapilloma, Choroid PlexusChoroid NeoplasmsPanuveitisAqueous HumorIridocyclitisUveaCiliary BodyIrisUveitis, SuppurativeVitreous BodyTuberculosis, OcularBehcet SyndromeRetinal VasculitisAutoimmune DiseasesChorioretinitisRats, Inbred LewUveomeningoencephalitic SyndromeArthritis, JuvenileHLA-B27 AntigenEyeToxoplasmosis, OcularRetinaArrestinRetinol-Binding ProteinsEye DiseasesEye Infections, ViralRetinitisEye ProteinsVisual AcuityPigment Epithelium of EyeCerebral Ventricle NeoplasmsCerebrospinal FluidChoroiditisFluorescein AngiographyEye InfectionsScleraSarcoidosisEpendymaFundus OculiGyrate AtrophyFluocinolone Acetonide
AnteriorIritisUveaType of uveitisVitreousDiffuseDisordersVisual acuityOptic neuritisPars planitisPanuveitisRetinitisNoninfectiousCiliary body and choroidChorioretinitisCommon form of uveitisSystemic diseasesUvealRetinal pigment epVascular diseaseGlaucomaDiagnosisMacularBlindnessAffectsRetina or choroidTypes of uveitisIncidence of uveitisClassification of uveitisConjunctivitisChronicClinicalChoroidalSevereIntraocular inflammationEtiologyOcular diseaseVasculitisScleraBilateralBacterialViralOccursPatientsDisorderIntermediate or posteriorAcuteInflammatory diseasesPosterior segment
Anterior35
  • Disseminated disease occurs when the fungus has spread outside of the lungs and may include clinical signs such as lameness, pain, seizures, anterior uveitis, and localized swelling. (wikipedia.org)
  • Iritis and irido-cyclitis (anterior uveitis) are most often mild. (medlineplus.gov)
  • With proper treatment, most attacks of anterior uveitis go away in a few days to weeks. (medlineplus.gov)
  • 1 Isolated anterior uveitis usually causes non-cystic retinal thickening that correlates well with disease activity. (reviewofophthalmology.com)
  • Currently, there are a limited number of reports of structural changes in the retina and choroid in acute anterior uveitis (AAU). (biomedcentral.com)
  • Acute anterior uveitis (AAU) is the most common type of uveitis among the general population. (biomedcentral.com)
  • In anterior uveitis, the primary site of inflammation is the anterior chamber, and diagnosis is made on the basis of slit-lamp biomicroscopy findings. (biomedcentral.com)
  • For these reasons, choroidal and retinal changes in active anterior uveitis are not well known. (biomedcentral.com)
  • however, the authors did not specify the etiology of anterior uveitis. (biomedcentral.com)
  • 5 Anterior chamber inflammation is categorized as "anterior uveitis", and includes iritis, iridocyclitis, and anterior cyclitis. (dovepress.com)
  • Finally, "pan-uveitis" describes the situation where inflammation is seen throughout the anterior chamber, vitreous, and retina or choroid. (dovepress.com)
  • In fatal disease, LASV immunostaining was most prominent in the anterior uvea, especially in the filtration angle, ciliary body, and iris and in and around vessels in the bulbar conjunctiva and peripheral cornea, where it co-localized with an endothelial marker (platelet endothelial cell adhesion molecule). (cdc.gov)
  • Overall, in this model, LASV antigen was restricted to the anterior uvea and was associated with mild chronic inflammation in animals with severe disease but was not detected in survivors. (cdc.gov)
  • A 51-year-old woman was referred with an anterior uveitis, initially presenting as a granulomatous iritis. (nih.gov)
  • Lymphocytic markers applied to the biopsy specimen and to the enucleated eye revealed a highly malignant T-cell lymphoma infiltrating the iris, ciliary body, anterior choroid, retina and the adjacent vitreous body. (nih.gov)
  • Typing for human leukocyte antigen-B27 is appropriate for patients with recurrent anterior uveitis. (aafp.org)
  • Uveitis is classified according to the predominant site of inflammation: anterior (anterior chamber), intermediate (vitreous), or posterior (retina or choroid). (aafp.org)
  • Adults who have a single episode of mild anterior uveitis that responds to treatment and who have no systemic signs or symptoms do not need further laboratory studies. (aafp.org)
  • Disorders like the seronegative spondyloarthropathies and juvenile idiopathic uveitis usually involve the anterior segment of the eye, but other conditions like Behçet syndrome, syphilis, and sarcoidosis can affect any location. (aafp.org)
  • Anterior uveitis is inflammation of the iris (iritis) or the iris and ciliary body. (allaboutvision.com)
  • If you have anterior uveitis, your doctor likely will prescribe, in addition to steroids, pupil-dilating eye drops to reduce pain. (allaboutvision.com)
  • Ocular involvement has been observed in 30% to 70% of BD patients, manifesting as anterior uveitis, posterior uveitis, panuveitis, and/or retinal vasculitis [ 1 3 4 ]. (ekjo.org)
  • The condition can affect the iris (anterior uveitis), ciliary body (intermediate uveitis), and choroid (posterior uveitis) parts of the eye and is often chronic. (nih.gov)
  • Coronaviruses can cause severe ocular disease in animals, including anterior uveitis, retinitis, vasculitis, and optic neuritis in feline and murine species. (cov19longhaulfoundation.org)
  • If the inflammation affects the iris and the ciliary body, it's called anterior uveitis or iridocyclitis . (allaboutvision.com)
  • It occurs in patients with granulomatous anterior uveitis such as in patients with Sarcoidosis. (webeyeclinic.com)
  • Anatomically, uveitis may be classified as anterior, intermediate, posterior or diffuse, depending on the portion of the uveal tract that is affected. (justia.com)
  • Anterior uveitis is localized primarily to the anterior segment of the eye and includes iritis and iridocyclitis. (justia.com)
  • Diffuse uveitis implies inflammation involving all parts of the eye, including anterior, intermediate, and posterior structures (The Merck Manual, 1999). (justia.com)
  • The acute uveitic stage is heralded by the onset of sequential blurring of vision in both eyes, 1-2 days after the onset of CNS signs, and is marked by bilateral granulomatous anterior uveitis, a variable degree of vitritis, thickening of the posterior choroid, edema of the optic nerve, and multiple serous retinal detachments (Fig 9-52). (aao.org)
  • Standard workups for uveitis included a detailed patient history and anterior and posterior segment biomicroscopy. (openophthalmologyjournal.com)
  • Late manifestations of complete VKH disease include evidence of previous early manifestations of the disease, as outlined above, with ocular depigmentation and nummular chorioretinal scars, retinal pigment epithelium (RPE) clumping and migration, or anterior uveitis. (medscape.com)
  • The symptoms of uveitis depend on whether it is anterior, intermediate, posterior or diffuse. (royoeye.com)
  • Topical application to the eye is the route of choice when targeting diseases affecting the ocular surface and anterior segment, whereas posterior segment conditions may require periocular, sub-Tenon and intravitreal injections. (touchophthalmology.com)
  • Iris or Anterior Uveitis - often a result of an underlying autoimmune disorder such as rheumatoid arthritis or ankylosing spondylitis. (newviewlasereye.com)
Iritis3
  • If you suffer from sensitivity to light (photophobia) from chronic iritis or uveitis, ask your optician about photochromic lenses . (allaboutvision.com)
  • Read more about uveitis and iritis . (allaboutvision.com)
  • Uveitis - Also commonly referred to as "iritis," uveitis is caused by inflammation along the uveal tract (iris, ciliary body, and choroid). (jucm.com)
Uvea13
Type of uveitis3
Vitreous2
  • Inflammation primarily affecting the vitreous is referred to as "intermediate uveitis", and includes pars planitis, posterior cyclitis, and hyalitis. (dovepress.com)
  • Its outer surface is in contact with the choroid and the inner surface with the vitreous body. (lecturio.com)
Diffuse7
  • Diffuse macular thickening with cystic changes in chronic uveitis. (reviewofophthalmology.com)
  • Diffuse uveitis has a combination of symptoms of all types of uveitis. (allaboutvision.com)
  • Naming example: Mrs. Jackson is a 32-year-old white schoolteacher from Virginia with a history of chronic bilateral diffuse granulomatous uveitis, headaches, hearing loss, and vitiligo. (medscape.com)
  • Although the devastating ocular symptoms of BD in the fundus are caused by obliterative and necrotizing vasculitis, histopathological studies of the choroid have demonstrated diffuse and focal infiltration by inflammatory cells, including CD4+ T cells and macrophages [ 7 8 ]. (ekjo.org)
  • Vogt-Koyanagi-Harada syndrome is a multisystem disease of presumed autoimmune etiology that is characterized by chronic, bilateral, diffuse, granulomatous panuveitis with accompanying integumentary, neurologic, and auditory involvement. (aao.org)
  • Early manifestations of complete VKH disease include diffuse choroiditis, which may include serous retinal detachment or focal areas of subretinal fluid. (medscape.com)
  • and diffuse uveitis affects structures both in the front and back of the eye. (royoeye.com)
Disorders14
  • Because the ocular changes produced by SCD can be seen in other diseases, it is important to rule out other causes of occlusion, including central retinal vein occlusion, Eales disease, and retinopathy secondary to diabetes and other disorders. (medscape.com)
  • Uveitis can be caused by autoimmune disorders . (medlineplus.gov)
  • Uveitis, or inflammation of the uveal tract (i.e., iris, ciliary body, and choroid), results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. (aafp.org)
  • Table 1 lists the main systemic disorders associated with uveitis, typical clinical findings, and suggested diagnostic studies. (aafp.org)
  • 1,8 However, carbonic anhydrase inhibitors may cause buoyancy disorders through their effects on swim bladder function, 3 and there are some anecdotal reports of fatal treatment outcomes, though fish may have been compromised by systemic disease prior to treatment. (vin.com)
  • It can be caused by infections, trauma, autoimmune disorders, or as a secondary condition to other diseases. (myfurrysoulmates.com)
  • Classification and standardization of uveitis is important, as it enhances the precision and comparability of clinical research from different centers and assists in the development of a complete picture of the course of the disorders and their response to treatment. (medscape.com)
  • Independently, Vogt, Koyanagi, and Harada described several patients during a 20-year period with bilateral uveitis , exudative retinal detachments, neurologic abnormalities, and disorders of the integument. (medscape.com)
  • While one of the most commonly used methods to treat uveitis caused by digestive tract disorders is to use steroid eye drops or immunosuppressants. (highcarbhealth.com)
  • It is idiopathic disease that is associated with multi-system disorders. (webeyeclinic.com)
  • While this can occur from blunt ocular trauma, it's most commonly idiopathic (60% of cases), and the remaining cases are often associated with autoimmune disorders (eg, Behçet's disease or most commonly juvenile idiopathic arthritis). (jucm.com)
  • Causes of posterior uveitis include infection, autoimmune disorders and inflammatory diseases. (eyecraftersny.com)
  • Inflammatory orbital disease, also called idiopathic orbital inflammatory syndrome and non-specific orbital inflammation, refers to eye disorders that involve the orbit. (orbit-eyecenter.com)
  • Intravitreal delivery of pharmacologic agents is the key method of drug delivery for posterior segment disease including retinal vascular disorders and posterior uveitis. (medscape.com)
Visual acuity2
  • One study that showed a 20-percent change in retinal thickness correlated well with a 10-letter change in visual acuity, suggesting that changes in SD-OCT could be a meaningful measure of treatment success in macular edema related to uveitis. (reviewofophthalmology.com)
  • Seven (8%) eyes (all with uveitis) presented with impaired visual acuity. (bvsalud.org)
Optic neuritis3
  • Inflammation of the overlying retina, called retinitis, or of the optic nerve, called optic neuritis, may occur with or without accompanying uveitis. (justia.com)
  • Posterior uveitis signifies any of a number of forms of retinitis, choroiditis, or optic neuritis. (justia.com)
  • Ocular involvement-presenting as chorioretinitis, uveitis, occlusive retinal vasculitis, or optic neuritis [ 4 , 5 ]-occurs in some cases of WNV infection, although the pathogenesis and sequelae of these complications are unclear. (molvis.org)
Pars planitis2
  • Another form of uveitis is pars planitis. (medlineplus.gov)
  • Intermediate uveitis, also called peripheral uveitis, is centered in the area immediately behind the iris and lens in the region of the ciliary body and pars plana, hence the alternate terms "cyclitis' and "pars planitis. (justia.com)
Panuveitis5
  • 1 Generalized intraocular inflammation is described as panuveitis, whereas inflammation centered in the optic nerve head with secondary peripapillary involvement is classified under posterior uveitis as neuroretinitis. (aafp.org)
  • Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S. In cases of more severe disease, posterior uveitis and panuveitis, the international trial showed that methotrexate was more effective in controlling inflammation. (nih.gov)
  • The First-line Antimetabolites for Steroid-sparing Treatment (FAST) Uveitis Trial enrolled and randomly assigned 216 patients with intermediate or posterior/panuveitis from India, the United States, Australia, Saudi Arabia and Mexico to methotrexate (107 participants) or mycophenolate (109 participants) treatment groups. (nih.gov)
  • In patients with posterior or panuveitis, the most severe forms, 74% in the methotrexate group achieved control at six months, versus 55% in the mycophenolate group, indicating that methotrexate was significantly more effective at controlling inflammation for this subtype of uveitis. (nih.gov)
  • Vogt-Koyanagi-Harada (VKH) disease is a multisystemic disorder characterized by granulomatous panuveitis with exudative retinal detachments that is often associated with neurologic and cutaneous manifestations. (medscape.com)
Retinitis2
Noninfectious2
  • Most uveitis seen in Western countries is noninfectious and appears to be autoimmune or autoinflammatory in nature, requiring treatment with immunosuppressive and/or anti-inflammatory drugs. (dovepress.com)
  • In Brazil and Saudi Arabia, it is the most commonly encountered cause of noninfectious uveitis. (aao.org)
Ciliary body and choroid3
Chorioretinitis3
  • Although CMV is the most common congenital infection in the developed world, affecting approximately 1% of all infants born in the United States, only 10% of all infants born in the United States with congenital CMV infection have symptomatic disease at birth, including chorioretinitis. (medscape.com)
  • Beyond the neonatal period, chorioretinitis can be diagnosed in diverse clinical conditions and can reflect newly acquired diseases or reactivation. (medscape.com)
  • The fundus displayed a pathologic phenomenon that was diagnosed as chorioretinitis, a form of posterior uveitis, which is an inflammatory response involving both the choroid layer, and the retina. (cdc.gov)
Common form of uveitis2
Systemic diseases6
  • Systemic diseases most often associated with uveitis in North America are the seronegative spondyloarthropathies, sarcoidosis, syphilis, rheumatoid arthritis, and reactive arthritis. (aafp.org)
  • Immunopathological inflammations of the ocular surface are associated with systemic diseases. (bvsalud.org)
  • Ocular manifestations of systemic diseases, p.374-418. (scielo.br)
  • Hyphema may also result from systemic diseases, including widespread inflammation ( Powell 2002 Powell C.C. 2002. (scielo.br)
  • Systemic diseases such as sarcoidosis Sarcoidosis Sarcoidosis is a multisystem inflammatory disease that causes noncaseating granulomas. (lecturio.com)
  • The search also included systemic diseases known to be associated with intraocular inflammation, e.g. sarcoidosis. (openophthalmologyjournal.com)
Uveal1
  • This session will focus on some of the more common conditions affecting the uveal tract, including uveitis, glaucoma, neoplasia and systemic disease. (cpd-solutions.com)
Retinal pigment ep2
  • Given its high degree of reproducibility, SD-OCT is an invaluable technique for characterizing pathologic features of the retina, including the retinal pigment epithelium, and in assessing disease activity and therapeutic response. (reviewofophthalmology.com)
  • Although intravitreal administration of therapeutics increases concentration in the area of diseased tissue (i.e. retina, choroid, retinal pigment epithelium), while reducing systemic side effects, other drug delivery options reviewed in this manuscript offer promise for posterior segment conditions. (medscape.com)
Vascular disease4
  • Dr. Chun Yuan, Professor in Radiology, and I co-direct the Vascular Imaging Laboratory at South Lake Union, and we have had a 20-year history of collaboration focused on the development and application of novel magnetic resonance imaging (MRI) techniques for characterization of cerebral and peripheral vascular disease. (uwmdi.org)
  • Because BD is a systemic vascular disease, these findings suggest that patients with BD and without any evidence of ocular involvement may still have subclinical choroidal involvement [ 11 ]. (ekjo.org)
  • Peripheral ulcerative keratitis is usually associated with collagen vascular disease, rheumatoid arthritis. (bvsalud.org)
  • Currently available, intravitreal, corticosteroid-release devices offer surgical and in-office management of retinal vascular disease and posterior uveitis. (medscape.com)
Glaucoma5
  • Glaucoma is a severe eye disease in which the pressure inside the eye, called intraocular pressure (IOP), increases. (simplydogowners.com)
  • Intraocular pressure (IOP) can be used as a general indicator of ocular disease, with increased IOP indicating glaucoma and decreased IOP associated with uveitis or other ocular inflammation. (vin.com)
  • Many cases of uveitis are chronic, and they can produce numerous possible complications, including clouding of the cornea, cataracts , elevated eye pressure (IOP), glaucoma , swelling of the retina or retinal detachment . (allaboutvision.com)
  • Inflammation from uveitis may result in a variety of other eye conditions, including glaucoma, cataracts, and cystoid macular edema, and ultimately may lead to permanent vision loss. (justia.com)
  • In this way, we speak of the strabismologist, if the ophthalmologist is a strabismus specialist, or the glaucomatologist, if he specialises in glaucoma, or the retinologist, if he works exclusively with patients with diseases of the retina. (icoftalmologia.com)
Diagnosis9
  • Primary care physicians may be asked to evaluate patients with uveitis when an underlying systemic diagnosis is suspected but not apparent from eye examination or history. (aafp.org)
  • Classifying uveitis according to the predominant site of inflammation can help narrow the differential diagnosis. (aafp.org)
  • This review provides a framework for primary care physicians who are asked to examine patients with uveitis when an underlying systemic diagnosis is suspected after ophthalmologic evaluation. (aafp.org)
  • To help clarify the diagnostic features of VKH disease, the International Committee on Nomenclature established revised criteria for the diagnosis of VKH disease, published in 2001. (medscape.com)
  • Since patients can have some or all of these symptoms in either bacterial or nonbacterial disease, it's important to look closely at differentiating factors to make the most accurate diagnosis. (jucm.com)
  • ICOftalmologia has broadened its scientific knowledge of eye diseases, improved the diagnosis of such diseases with the aid of sophisticated examinations and has developed surgical techniques for diseases that were, until recently, incurable. (icoftalmologia.com)
  • Ophthalmic A&E Department: opened in 1989, offering a speedy diagnosis and treatment for everything ranging from mild complaints to serious, life-threatening diseases that may even require surgery. (icoftalmologia.com)
  • The differential diagnosis of uveitis may include a broad spectrum of ocular diseases, e.g. trauma, degenerative diseases, dystrophies, diabetic retinopathy or vascular occlusion. (openophthalmologyjournal.com)
  • It was the aim of this study to analyze the age distribution of patients presenting with endogenous uveitis in our clinic, and thus to estimate the priority that should be awarded to a uveitis work-up for the differential diagnosis of endogenous uveitis in the elderly patient. (openophthalmologyjournal.com)
Macular5
  • Different forms of macular edema in uveitis. (reviewofophthalmology.com)
  • ERM formation is often found in conjunction with vitreoretinal traction, and a tractional mechanism may contribute to the onset of macular edema in uveitis. (reviewofophthalmology.com)
  • En este campo estamos interesados en la patogenia del edema macular. (biocrucesbizkaia.org)
  • In this review, we describe some evidence, largely from rodent studies, that supports the possible role of a dysbiotic gut microbiota in the onset and exacerbation of ocular diseases, primarily diabetic retinopathy, age-related macular degeneration, choroidal neovascularization, and uveitis. (springer.com)
  • The focus of this brief review is to describe the alterations in the gut microbiota that may exacerbate ocular phenotypes, including diabetic retinopathy, age-related macular edema, choroidal neovascularization, uveitis, and Sjögren's disease. (springer.com)
Blindness5
  • Choroidal neovascularization is a leading cause of impaired vision and blindness in eyes with uveitis, and SD-OCT is a useful way to detect it and monitor treatment (See Figure 2) . (reviewofophthalmology.com)
  • Uveitis, a significant cause of blindness worldwide, is a term applied to a wide range of conditions that are characterized by intraocular inflammation. (dovepress.com)
  • Ocular manifestations of SLE are common and may lead to permanent blindness from the underlying disease or therapeutic side effects. (bmj.com)
  • On the extreme end, if left untreated, some retinal diseases can cause severe vision loss or blindness. (centreforsight.net)
  • Uveitis is the third leading cause of blindness in the developed world. (justia.com)
Affects16
  • Pseudorabies (Morbus Aujeszky) is an infectious disease that primarily affects swine, but can also cause a fatal disease in dogs with signs similar to rabies. (wikipedia.org)
  • Blastomycosis* is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans. (wikipedia.org)
  • Histoplasmosis* is a fungal disease caused by Histoplasma capsulatum that affects both dogs and humans. (wikipedia.org)
  • The disease in dogs usually affects the lungs and small intestine. (wikipedia.org)
  • Coccidioidomycosis* is a fungal disease caused by Coccidioides immitis or Coccidioides posadasii that affects a variety of species, including dogs. (wikipedia.org)
  • Sporotrichosis is a fungal disease caused by Sporothrix schenckii that affects both dogs and humans. (wikipedia.org)
  • Posterior uveitis affects the back part of the eye. (medlineplus.gov)
  • However, researchers who reviewed 522 international articles concerning the causes and patterns of uveitis and 22 major epidemiology reviews concluded it affects 52.4 per 100,000 people. (allaboutvision.com)
  • Since Crohn's disease affects the digestive tract and causes inflammation of the organs involved in digestion, a host of other health issues are caused due to untreated Crohn's disease. (highcarbhealth.com)
  • Crohn's disease affects the digestive tract, anus, and mouth the most. (highcarbhealth.com)
  • Because Crohn's disease affects the rate at which nutrients are absorbed in the digestive tract, there are several extra intestinal symptoms of the disease. (highcarbhealth.com)
  • Crohn's disease does not only affect the absorption of nutrients in the digestive tract, but it also affects the absorption of other important secretes such as bile salts. (highcarbhealth.com)
  • Posterior uveitis affects the back of the eye, which includes the retina and an eye layer called the choroid. (eyecraftersny.com)
  • Although the disease more commonly affects some of the more darkly pigmented ethnic groups-including people of Asian, Hispanic, Native American, and Middle Eastern ancestry-and is uncommon among whites, VKH syndrome is also rare among sub-Saharan Africans, suggesting that additional factors, other than skin pigmentation, are important in its pathogenesis. (aao.org)
  • Uveitis is classified by the structures it affects, the underlying cause, and whether it is chronic (lasting more than 6 weeks), or acute in nature. (royoeye.com)
  • Uveitis usually affects people between 20-50 years of age. (royoeye.com)
Retina or choroid1
Types of uveitis1
  • Symptoms of these types of uveitis include blurred vision and floaters , typically in both eyes. (allaboutvision.com)
Incidence of uveitis2
  • The annual incidence of uveitis in North America ranges from 17 to 52 per 100,000 persons, and the prevalence ranges from 58 to 115 per 100,000 persons. (aafp.org)
  • Recently, population-based studies have shown an increase in the incidence of uveitis with inreasing age. (openophthalmologyjournal.com)
Classification of uveitis2
  • The most widely used classification of uveitis is the one devised by the International Uveitis Study Group (IUSG) in 1987, based on the anatomical location of the inflammation. (medscape.com)
  • There was a consensus by the group members that the anatomical classification of uveitis based on criteria defined by the International Uveitis Study Group (IUSG) should be used. (medscape.com)
Conjunctivitis6
  • Lassa virus (LASV), a hemorrhagic fever virus endemic to West Africa, causes conjunctivitis in patients with acute disease. (cdc.gov)
  • Conjunctivitis (n=26/56.5%) and uveitis (n=23/50%) were the most frequent ocular manifestations. (bvsalud.org)
  • CONCLUSIONS: Conjunctivitis was the most common ocular manifestation in our TRAPS, FMF, MWS and HIDS patients, and uveitis predominated in Blau syndrome. (bvsalud.org)
  • Infectious conjunctivitis or "pink eye" is common in the pediatric population, accounting for 2.7% of diagnoses in pediatric urgent care.1 However, it can be difficult to distinguish viral from bacterial disease, and it's important to not presume the cause is infectious. (jucm.com)
  • Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt thereof. (justia.com)
  • Also provided is a pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating a subject suffering from an OID, uveitis, bacterial conjunctivitis, viral conjunctivitis, an inflammation of the orbital tissue, the lacrimal apparatus, the eyelid, the cornea, the retina or the optic pathway. (justia.com)
Chronic6
  • In Fuchs' uveitis syndrome, patients exhibit a relatively thin choroid, which might be the result of the chronic inflammation associated with the disease [ 11 ]. (biomedcentral.com)
  • According to the SUN criteria, disease is further classified according to onset (sudden or insidious), duration (limited or persistent), and course (acute, recurrent, or chronic). (dovepress.com)
  • Chronic disease is treated with tear supplements, warm compresses, and occasionally oral antibiotics (eg, a tetracycline or azithromycin) for meibomian gland dysfunction or with eyelid hygiene and tear supplements for seborrheic blepharitis. (merckmanuals.com)
  • Chronic overeating also tends to exert the digestive system and cause strain due to which the symptoms of Crohn's disease start to appear. (highcarbhealth.com)
  • They are also due to the low absorption of vitamins and minerals and chronic diarrhea caused by Crohn's and are often also the result of the primary inflammation that is caused by the disease. (highcarbhealth.com)
  • Chronic Granulomatous Disease can affect the fetus in utero and present as congenital abnormalities Congenital Abnormalities Malformations of organs or body parts during development in utero. (lecturio.com)
Clinical11
  • Canine coronavirus is a gastrointestinal disease that is usually asymptomatic or with mild clinical signs. (wikipedia.org)
  • According to a study performed in the Tucson and Phoenix area, 28% of dogs will test positive for exposure to the fungus by two years of age, but only 6% of the dogs will be ill with clinical disease. (wikipedia.org)
  • whilst both may present with similar clinical features, they are best considered as distinct disease entities since the underlying pathophysiology and treatment strategies are very different. (dovepress.com)
  • Breed-related eyelid disease such as entropion, ectropion and trichiasis can represent significant clinical challenges in practice. (cpd-solutions.com)
  • Various genetic, epigenetic, immunoregulatory, environmental and infectious factors contribute to the susceptibility, onset, progression and prognosis of the clinical disease in a given patient. (bmj.com)
  • In 2005, the Standardization of Uveitis Nomenclature (SUN) Working Group standardized the methods for reporting clinical data (diagnostic terminology, inflammation grading schema, and outcome measures) for uveitis. (medscape.com)
  • In 2008, the International Uveitis Study Group (IUSG) designed a simplified, clinical classification system for uveitis based on etiological criteria. (medscape.com)
  • A retrospective analysis was used to examine clinical features of non-uveitic patients with BD (NUBD group), patients with a previous history of Behçet uveitis in an inactive state (IUBD group), and healthy controls were evaluated from October 2014 to September 2015. (ekjo.org)
  • That is, the highly vascularized choroid is likely to be affected, regardless of whether clinical uveitis is present. (ekjo.org)
  • Based on this head-to-head clinical trial, methotrexate is as good as or better than mycophenolate for treating uveitis. (nih.gov)
  • The clinical features of VKH syndrome also vary depending on the stage of the disease. (aao.org)
Choroidal5
  • It provides in vivo, cross-sectional, histologic information of the choroid and allows visualization of choroidal vascular structures and measurement of choroidal thickness [ 6 ]. (biomedcentral.com)
  • To investigate whether subfoveal choroidal thickness, measured using enhanced depth imaging optical coherence tomography (EDI-OCT), is an indicator of subclinical ocular or systemic inflammation in eyes with Behçet disease (BD) without active ocular inflammation. (ekjo.org)
  • In addition, imaging modalities, such as indocyanine green angiography, in patients with active Behçet uveitis (BU) have shown irregular filling of the choriocapillaris, choroidal filling defects, and dye leakage from choroidal vessels, suggesting involvement of the choroid in BD [ 9 10 ]. (ekjo.org)
  • The development of enhanced depth imaging optical coherence tomography (EDI-OCT) has improved visualization of choroidal tissue, allowing choroidal involvement to be investigated noninvasively in many diseases. (ekjo.org)
  • EDI-OCT has shown significantly increased choroidal thickness in BD patients with active uveitis [ 11 12 ], as well as in the uninvolved eyes of patients with unilateral BU, compared with control subjects [ 11 ]. (ekjo.org)
Severe7
  • Sometimes certain types of immune-suppressant drugs are used to treat severe uveitis. (medlineplus.gov)
  • 4 - 7 Up to 35% of patients with uveitis have severe visual impairment, and roughly 10% are legally blind. (aafp.org)
  • Consuming alcohol tends to lead to severe flares and greater inflammation for those who suffer from Crohn's disease. (highcarbhealth.com)
  • Since December 2019, coronavirus disease 2019 (COVID-19) has become a global pandemic caused by the highly transmissible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (cov19longhaulfoundation.org)
  • Severe eye complications and poor visual prognosis were associated with uveitis. (bvsalud.org)
  • Adults with monogenic autoinflammatory diseases seem to exhibit a less severe ophthalmologic presentation than paediatric patients. (bvsalud.org)
  • Allergic and immunopathological diseases of the ocular surface are inflammations that can occur with mild to severe symptoms that cause visual impairment. (bvsalud.org)
Intraocular inflammation1
  • Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of sight loss in the working population. (dovepress.com)
Etiology1
  • The discrepancies in results between these two studies are likely because of the small sample size or differences in disease etiology. (biomedcentral.com)
Ocular disease4
  • Ocular disease is common in aquarium fish. (vin.com)
  • Exophthalmia is a common indication of systemic or primary ocular disease in fish, and may result from gas emboli (idiopathic gaseous exophthalmia or environmentally-induced gas bubble disease), trauma, viral or bacterial infection or neoplasia. (vin.com)
  • Probable VKH disease: Patients with probable VKH disease include those with isolated ocular disease. (medscape.com)
  • Future studies of the gut microbiota and its relationship with ocular disease will increase our understanding of the gut-eye axis and lead to innovative therapeutic approaches to treating ocular diseases. (springer.com)
Vasculitis1
  • Behçet disease (BD) is a systemic immune-mediated vasculitis, affecting both arteries and veins in multiple organs [ 1 2 ]. (ekjo.org)
Sclera3
Bilateral3
  • Bilateral, multifocal serous detachments in a patient with Vogt-Koyanagi-Harada disease. (medscape.com)
  • Defining features of early-stage VKH include bilateral serous retinal detachments, or, characteristic uveitis with at least 2 of the following neurologic findings: headache, tinnitus, dysacusis, meningismus, or cerebrospinal fluid pleocytosis. (medscape.com)
  • In four of these cases, the cause of hyphema was trauma and remaining case was caused by phacoclastic uveitis in a dog with bilateral hypermature cataract. (scielo.br)
Bacterial4
  • Brucellosis is a sexually transmitted bacterial disease that can cause uveitis, abortion, and orchitis in dogs. (wikipedia.org)
  • Following shifts in gut bacterial composition, the immune system surpasses microbial tolerance and progresses to an inflammatory state, which can induce tissue damage throughout the body and promote disease pathogenesis. (springer.com)
  • 027.8 Other 027.9 Unspecified OTHER BACTERIAL DISEASES (030-041) Excludes: bacterial venereal diseases (098. (cdc.gov)
  • It is provided as an additional code where it is desired to identify the bacterial agent in diseases classified elsewhere. (cdc.gov)
Viral4
  • Rabies (hydrophobia) is a fatal viral disease that can affect any mammal, although the close relationship of dogs with humans makes canine rabies a zoonotic concern. (wikipedia.org)
  • In viral hemorrhagic fever disease, ocular manifestations are not limited to LF and are well described for infection with Ebola virus (EBOV) ( 11 , 12 ), Marburg virus ( 13 ), and Rift Valley fever virus (RVFV) ( 14 - 16 ). (cdc.gov)
  • Recently, the implications of viral persistence in the eye and other immunoprivileged sites have been highlighted in Ebola virus disease (EVD) ( 12 , 17 ). (cdc.gov)
  • Herpes Zoster Ophthalmicus (HZO), commonly known as shingles, is a viral disease characterized by a unilateral painful skin rash in one or more dermatome distributions of the fifth cranial nerve (trigeminal nerve), shared by the eye and ocular adnexa. (eyewiki.org)
Occurs4
  • Rocky Mountain spotted fever* is a rickettsial disease that occurs in dogs and humans. (wikipedia.org)
  • Inflammation occurs in the area called the pars plana, which is located between the iris and the choroid. (medlineplus.gov)
  • VKH disease occurs more commonly in patients with a genetic predisposition to the disease, including those from Asian, Middle Eastern, Hispanic, and Native American populations. (medscape.com)
  • Inflammatory orbital disease occurs due to an underlying condition. (orbit-eyecenter.com)
Patients22
  • [ 8 ] These changes are most common in hemoglobin SS disease but can also occur in patients with hemoglobin SC and hemoglobin S. (medscape.com)
  • It can occur in many patients with hemoglobin SS and hemoglobin SC disease. (medscape.com)
  • This is a peripheral retinal change most frequent in patients with hemoglobin SC but also can be present in patients with hemoglobin S-thalassemia disease, homozygous hemoglobin SS, and hemoglobin AS and hemoglobin AC disease. (medscape.com)
  • It is crucial that we continue to develop new therapies for use in uveitis that aim to suppress disease activity, prevent accumulation of damage, and preserve visual function for patients with the minimum possible side effects. (dovepress.com)
  • Uveitis is caused by a systemic disease in 30% to 45% of patients. (aafp.org)
  • Routine radiography and serologic studies are not indicated for all patients with uveitis. (aafp.org)
  • Drug-induced uveitis should be considered in patients with unexplained uveitis beginning days to months after starting a new medication. (aafp.org)
  • Approximately 30% to 45% of patients with uveitis have a causally associated systemic disease. (aafp.org)
  • Several human leukocyte antigen (HLA) associations have been found in patients with VKH disease, including HLA-DR4, HLA-DR53, and HLA-DQ4. (medscape.com)
  • Despite differences in their patients, the manifestations appeared to represent a spectrum of disease, and several authors suggested that the disorder should be termed Vogt-Koyanagi-Harada syndrome (see the image below). (medscape.com)
  • Patients with complete VKH disease also must have evidence of neurologic and auditory manifestations, as well as integumentary signs. (medscape.com)
  • Incomplete VKH disease: Patients with incomplete VKH disease have either neurologic and auditory manifestations or integumentary signs, but not both. (medscape.com)
  • This study gives doctors and their patients with uveitis a starting point when considering treatment beyond corticosteroids," said lead study author Nisha Acharya, M.D., M.S., University of California, San Francisco. (nih.gov)
  • OBJECTIVES: Ophthalmologic involvement in monogenic autoinflammatory diseases has been explored mainly in paediatric patients. (bvsalud.org)
  • The aim of this study is to characterise ophthalmologic manifestations, therapeutic management and visual outcomes in a Spanish (UVESAI) cohort of adult/paediatric patients with monogenic autoinflammatory diseases. (bvsalud.org)
  • METHODS: Multicentre and retrospective study of patients with monogenic autoinflammatory diseases and ocular involvement. (bvsalud.org)
  • A genetic predisposition for the development of the disease is further supported by the strong association with HLA-DR4 among Japanese patients and with HLA-DR1 or HLA-DR4 among Hispanic patients from southern California. (aao.org)
  • Endogenous uveitis has long been considered to be uncommon in elderly patients. (openophthalmologyjournal.com)
  • It was the aim of this study to analyse the age distribution of patients presenting with endogenous uveitis in the setting of an eye centre. (openophthalmologyjournal.com)
  • A large number of patients presenting with endogenous uveitis is in the elderly age group. (openophthalmologyjournal.com)
  • Only patients suffering from active endogenous uveitis were included. (openophthalmologyjournal.com)
  • A varicella-zoster ( shingles) vaccination is recommended for patients over the age of 50 or in adults aged 18 years and older who are or will be at increased risk of HZ due to immunodeficiency or immunosuppression caused by known disease or therapy. (eyewiki.org)
Disorder3
  • Your optician often can identify the cause of uveitis if there has been trauma to the eye or you have an infectious or immunological systemic disorder. (allaboutvision.com)
  • Vogt-Koyanagi-Harada (VKH) disease is a multisystem autoimmune inflammatory disorder with ocular, auditory, skin, and neurologic involvement. (medscape.com)
  • Although the pathogenesis of VKH disease is uncertain, the wide spectrum of findings in this disorder suggests a central mechanism to account for the multisystem manifestations. (medscape.com)
Intermediate or posterior1
  • Primary ocular lymphoma should be considered in persons older than 50 years with persistent intermediate or posterior uveitis that does not respond to anti-inflammatory therapy. (aafp.org)
Acute1
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
Inflammatory diseases1
  • This review summarizes the applications for SD-OCT imaging in various ocular inflammatory diseases. (reviewofophthalmology.com)
Posterior segment2
  • Disease of the posterior segment of the eye that is associated with uveitis and inflammation of the choroid, retina, retinal vessels and optic disc. (webeyeclinic.com)
  • Purpose of review Emerging developments and research for drug delivery to the posterior segment offer a promising future for the treatment of vitreoretinal disease. (medscape.com)