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AdenocarcinomaCervix UteriUterine Cervical NeoplasmsCarcinoma, Squamous CellUterine Cervical DysplasiaCervical RipeningHysterectomyCervical Intraepithelial NeoplasiaPapillomaviridaeCarcinoma, AdenosquamousUterine Cervical DiseasesBrachytherapyCarcinoma in SituAdenocarcinoma, MucinousImmunohistochemistryUterine NeoplasmsPrecancerous ConditionsAdenosarcomaBalsamsLung NeoplasmsPapillomavirus InfectionsEsophageal NeoplasmsPancreatic NeoplasmsNeoplasm StagingColposcopyVaginal NeoplasmsTumor Virus InfectionsTumor Markers, BiologicalCervix MucusAdenocarcinoma, PapillaryBarrett EsophagusCarcinoma, Pancreatic DuctalPrognosisStomach NeoplasmsAdenocarcinoma, Bronchiolo-AlveolarNeoplasms, Multiple PrimaryNeoplasm InvasivenessConizationCarcinomaMyoblasts, Smooth MuscleMetaplasiaPregnancyDNA Probes, HPVParturitionLabor, ObstetricBiopsyCytodiagnosisCarcinoma, EndometrioidEndometrial NeoplasmsCardiaCarcinoma, NeuroendocrineLymphatic MetastasisImmunoenzyme TechniquesMixed Tumor, MullerianRetrospective StudiesColonic NeoplasmsSurvival RateDNA, NeoplasmDNA, ViralPolymerase Chain ReactionCell Line, TumorGene Expression Regulation, NeoplasticVaginaTreatment OutcomeFocal Epithelial HyperplasiaRadiotherapy DosageEpitheliumNeoplasm Recurrence, LocalPapanicolaou TestSurvival AnalysisPelvisCombined Modality TherapyAntigens, NeoplasmEsophagogastric JunctionUterusHuman papillomavirus 18Disease-Free SurvivalKeratinsDisease ProgressionNeoplasm ProteinsKi-67 AntigenObstetric Labor, PrematureHuman papillomavirus 16RNA, MessengerKeratin-7Cyclin-Dependent Kinase Inhibitor p16Carcinoma 256, WalkerCarcinoma, Adenoid CysticCisplatinNeoplasmsAlphapapillomavirusTime FactorsChromosomes, Human, Pair 3Dermatan SulfateFollow-Up StudiesReverse Transcriptase Polymerase Chain ReactionIncidenceCell Transformation, NeoplasticTumor Suppressor Protein p53Intestinal Neoplasms

VaginaCervicalPrognosisSquamousSerousAriseRareCasesPattern in HPV-Associated Endocervical AdenocarcinomaEndocervical adenocarcinomasSituHuman papillomavirusLesionEndometrioid adenocarcinomaImmunohistochemicalEndometrialCervical cancerDiagnostic challengeUterusRetrospective StudySquamousOvarianCommonFeaturesWomenTreatmentReport

Vagina4

• Gynecological examination showed that: the vulva and vagina were normal, but there was papillary vegetation about 1.5 × 1.5 cm in size located at six o'clock of cervix, easy bleeding. (biomedres.info)
• It is thought to originate from the mesonephric remnants ( 1 - 3 ), which are usually located in the lateral wall of the vagina and uterine cervix, the broad ligament, and the ovarian hilum ( 4 , 5 ). (iiarjournals.org)
• The cervix projects into the vagina and continues up to the lower uterine segment. (medscape.com)
• The portion of the cervix exposed to the vagina is most commonly covered with squamous epithelium. (medscape.com)

Cervical3

• Villoglandular adenocarcinoma of the cervix is a rare type of cervical cancer that, in relation to other cervical cancers, is typically found in younger women and has a better prognosis. (wikipedia.org)
• In 1994, it was classified as the pathological type of cervical cancer by WHO in 1994, which is a subtype of cervical adenocarcinoma. (biomedres.info)
• It is this vulnerable area of the cervix, where columnar cells are actively undergoing metaplastic change to squamous epithelium, in which the majority of cervical malignancies occur. (medscape.com)

Prognosis3

• Villoglandular papillary adenocarcinoma is a recently described form of adenocarcinoma of the uterine cervix, which apparently affects young women and seems to have a favorable course with an excellent prognosis. (bvsalud.org)
• Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
• Conclusion: Uterine MLA is a highly aggressive gynecological malignancy, showing unique morphological and molecular features, frequent recurrences and metastases, as well as poor prognosis. (iiarjournals.org)

Squamous1

• Squamous cell carcinoma and adenocarcinoma are the most common variants that arise in the cervix. (medscape.com)

Serous1

• Diverse growth patterns make it difficult to distinguish uterine MLA from more commonly encountered histological types of endometrial carcinoma, including endometrial endometrioid carcinoma (EC) ( 10 ), serous carcinoma (SC), and carcinosarcoma (CS). (iiarjournals.org)

Arise1

• A similar lesion, villoglandular adenocarcinoma of the endometrium, may arise from the inner lining of the uterus, the endometrium. (wikipedia.org)

Rare3

• Villoglandular Papillary Adenocarcinoma (VGPA), also named Villoglandular Adenocarcinoma (VGA), refers to a rare welldifferentiated adenocarcinoma of uterine cervix. (biomedres.info)
• Background/Aim: Uterine mesonephric-like adenocarcinoma (MLA) is a rare malignant tumor of the female genital tract. (iiarjournals.org)
• Mesonephric adenocarcinoma (MA) is a rare malignant tumor of the female genital tract. (iiarjournals.org)

Cases2

• 4 cases of villoglandular papillary adenocarcinoma of uterine cervix admitted from 2001 to 2009 in Children's Hospital, Shanxi Provincial People's Hospital were analysed retrospectively, including detailed clinical data. (biomedres.info)
• Patients and Methods: We reviewed 237 endometrial carcinoma cases and investigated the clinicopathological and molecular characteristics of uterine MLA. (iiarjournals.org)

Pattern in HPV-Associated Endocervical Adenocarcinoma2

• Molecular Correlates of Invasion Pattern in HPV-Associated Endocervical Adenocarcinoma: Emergence of Two Distinct Risk-Stratified Tiers. (stanford.edu)
• Villoglandular Pattern in HPV-associated Endocervical Adenocarcinoma is Associated With Excellent Prognosis: A Reappraisal of 31 Cases Using IECC and Silva Pattern Classification. (patologia.ro)

Endocervical adenocarcinomas2

• BACKGROUND: Most endocervical adenocarcinomas are human papillomavirus (HPV)-related cancers associated with p16 immunostaining. (bvsalud.org)
• The pattern-based (Silva) classification of invasive HPV-associated endocervical adenocarcinomas (HPVA) is an established and reproducible method to predict outcomes for this otherwise stage-dependent group of tumors. (stanford.edu)

Situ3

• 9. Management and follow-up of patients with adenocarcinoma in situ of the uterine cervix. (nih.gov)
• Final histological examination and HPV genotyping revealed HPV18-related in situ endometrioid adenocarcinoma in the endocervix and HPV18-related invasive endometrioid adenocarcinoma in the endometrium and both ovaries. (bvsalud.org)
• Clear Cell Adenocarcinoma In Situ as a Potential Precursor Lesion for Sporadic Invasive Endocervical Clear Cell Adenocarcinoma. (patologia.ro)

Human papillomavirus1

• Clear Cell Carcinoma (CCC) of the Cervix Is a Human Papillomavirus (HPV)-independent Tumor Associated With Poor Outcome: A Comprehensive Analysis of 58 Cases. (patologia.ro)

Lesion2

• A similar lesion, villoglandular adenocarcinoma of the endometrium, may arise from the inner lining of the uterus, the endometrium. (wikipedia.org)
• DIAGNOSES: The specimen of hysterectomy in our hospital displayed a lesion confined to the uterine cervix showing the same morphology and immunohistochemical profiles as ECC. (bvsalud.org)

Endometrioid adenocarcinoma2

• Mucin-depleted usual-type ECA is 1 end of morphological lineage of usual-type ECA and morphologically may show endometrioid features, which could cause diagnostic challenge with uterine endometrioid adenocarcinoma (EEC) and primary endometrioid ECA, especially in the setting of small biopsy and endocervical curettage (ECC). (bvsalud.org)
• OBJECTIVE: Endocervical and endometrioid adenocarcinoma have marked overlapping features and the differentiation between them is important for their accurate management. (bvsalud.org)

Immunohistochemical1

• 16. The clinicopathologic and immunohistochemical features of villoglandular adenocarcinoma of uterine cervix. (nih.gov)

Endometrial1

• Clear-cell carcinoma , mucinous adenocarcinoma , undifferentiated carcinoma , dedifferentiated carcinoma , and serous adenocarcinoma are less common types of endometrial adenocarcinomas. (cancer.org)

Cervical cancer2

• Villoglandular adenocarcinoma of the cervix is a rare type of cervical cancer that, in relation to other cervical cancers, is typically found in younger women and has a better prognosis. (wikipedia.org)
• 5. Tumor Handling of Early-stage Cervical Cancer: A Literature Analysis of Villoglandular Adenocarcinoma of the Cervix. (nih.gov)

Diagnostic challenge1

• 6. Villoglandular papillary adenocarcinoma of the uterine cervix: a diagnostic challenge. (nih.gov)

Uterus3

• The cervix is the lower end of the uterus that joins it to the vagina. (cancer.org)
• When people talk about cancer of the uterus, they usually mean cancers that start in the body of the uterus, not the cervix. (cancer.org)
• The uterine cervix comprises the distal third of the uterus. (medscape.com)

Retrospective Study1

• Horizontal tumor extent (HZTE) has limited prognostic significance in 2018 FIGO stage I endocervical adenocarcinoma (ECA): a retrospective study of 416 cases. (patologia.ro)

Squamous3

• Squamous cell carcinoma and adenocarcinoma are the most common variants that arise in the cervix. (medscape.com)
• It is this vulnerable area of the cervix, where columnar cells are actively undergoing metaplastic change to squamous epithelium, in which the majority of cervical malignancies occur. (medscape.com)
• Squamous and Glandular Epithelial Tumors of the Cervix: A Pragmatical Review Emphasizing Emerging Issues in Classification, Diagnosis, and Staging. (patologia.ro)

Ovarian2

• 2. Is the ovarian preservation safe in young women with stages IB-IIA villoglandular adenocarcinoma of the uterine cervix? (nih.gov)
• Additional molecular analyses performed in two patients identified the same HPV integration sites in both the ovarian and cervical tumors, confirming that the ovarian mass was a metastasis from the cervical adenocarcinoma. (bvsalud.org)

Common1

• RATIONALE: Usual-type endocervical adenocarcinoma (ECA), high-risk HPV associated, is the most common type of glandular carcinoma in the endocervix. (bvsalud.org)

Features1

• 13. Villoglandular adenocarcinoma of cervix--a tumour with bland cytological features: report of a case missed on cytology. (nih.gov)

Women2

• 19. Survival of women with microinvasive adenocarcinoma of the cervix is not improved by radical surgery. (nih.gov)
• CASE PRESENTATION: Two women presented with HPV18 cervical adenocarcinoma. (bvsalud.org)

Treatment2

• 12. Prognostic factors influencing decisions about surgical treatment of villoglandular adenocarcinoma of the uterine cervix. (nih.gov)
• 15. Conservative treatment of microinvasive adenocarcinoma of uterine cervix: long-term follow-up. (nih.gov)

Report3

• 8. Villoglandular papillary adenocarcinoma of the cervix: case report. (nih.gov)
• 14. Well-differentiated papillary villoglandular adenocarcinoma of the uterine cervix: a case report. (nih.gov)
• 18. Villoglandular adenocarcinoma of the cervix: a case report. (nih.gov)