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CystitisUrinary BladderUrinary Bladder DiseasesUrotheliumUrinary Bladder NeoplasmsUrinationInflammationCystitis, InterstitialAdministration, IntravesicalReceptors, Proteinase-ActivatedZymosanDilatation, PathologicSubstance PUrinary Bladder CalculiCyclophosphamideVisceraReflexUrinary Bladder, OveractiveDisease Models, AnimalCystoscopyCarcinoma, Transitional CellRats, Sprague-DawleyUrinary Tract InfectionsUrinary Bladder, NeurogenicUrinary Bladder Neck ObstructionMice, Inbred C57BLButylhydroxybutylnitrosamineUrinary TractHematuriaUrineUrinary CatheterizationInflammation MediatorsUrodynamicsMuscle, SmoothUrinary RetentionUrinary IncontinencePyelonephritisCystectomyBufo marinusUrinary Bladder FistulaAnti-Infective Agents, UrinaryPelvic PainUroplakin IIIUroplakin IIUrethraMuscle ContractionUrinary CalculiPentosan Sulfuric PolyesterBK VirusMucous MembraneAcroleinUrinary DiversionUrinalysisImmunohistochemistry
InterstitialUrethraInfectionsUrethritisBiopsyTumorsObstructionBacteriaOveractiveUrgencyKidneysStonesDysfunctionUrinationHematuriaNeurogenic bladderUTIsUrinateUretersChronic cystitisFrequentPainfulCystoscopyPelvicBenign prostatic hInfection and inflammationHunnerDysuriaCommonlyAcuteDisordersMucosalDiseasesAbdomenCysticCancerNervesCells lining thePainFemale urinaryTreatmentTreatmentsHealthy bladder
Interstitial40
  • Interstitial cystitis (bladder pain syndrome, Hunner ulcer) is a painful bladder disease characterized by chronic urinary urgency, frequency, and pain without evidence of bacterial infection. (medscape.com)
  • Nearly 90% of patients with interstitial cystitis are women. (medscape.com)
  • Interstitial cystitis is best diagnosed on the basis of its clinical features. (medscape.com)
  • There are no clear diagnostic criteria for interstitial cystitis, and the incidence is unknown. (medscape.com)
  • The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has reported on urologic chronic pelvic pain disorders-specifically, interstitial cystitis/painful bladder syndrome (IC/PBS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). (medscape.com)
  • [ 9 ] In a study of white-matter microstructure in women with interstitial cystitis/bladder pain syndrome evaluated by diffusion tensor imaging, white-matter abnormalities were identified that correlated with pain severity, urinary symptoms, and impaired quality of life. (medscape.com)
  • [ 6 ] In another study, females with interstitial cystitis displayed increased gray-matter volume in several regions of the brain, including the right primary somatosensory cortex, the superior parietal lobule bilaterally, and the right supplementary motor area. (medscape.com)
  • Interstitial Cystitis (IC) refers to an uncomfortable and annoying inflammatory condition of the bladder. (digitalnaturopath.com)
  • The interstitial cystitis patient has a small capacity, irritated bladder. (digitalnaturopath.com)
  • Interstitial cystitis must be diagnosed with the use of the cystoscope, an instrument which can directly visualize the interior of the bladder. (digitalnaturopath.com)
  • Medical treatments for interstitial cystitis have included overstretching of the bladder with water, instillation of a dilute silver nitrate solution into the bladder, and steroid use. (digitalnaturopath.com)
  • Currently, treatments for interstitial cystitis are aimed at relieving symptoms rather than achieving a cure. (digitalnaturopath.com)
  • A good site to visit for conventional information on this topic is the Interstitial Cystitis Association . (digitalnaturopath.com)
  • Vestibulitis may sometimes be part of bladder and/or urethral inflammation as seen in the interstitial cystitis or urethral syndrome. (digitalnaturopath.com)
  • Interstitial cystitis and endometriosis can cause similar symptoms, like chronic pelvic pain, lower back pain, and pain during sex. (healthline.com)
  • Interstitial cystitis is a painful disorder affecting your bladder. (healthline.com)
  • This article will explore the link between interstitial cystitis and endometriosis. (healthline.com)
  • Pain that often happens with a full bladder or that improves after urination is more likely to be interstitial cystitis. (healthline.com)
  • Interstitial cystitis , also called bladder pain syndrome, is a disorder characterized by irritation and inflammation of your bladder walls. (healthline.com)
  • The symptoms of interstitial cystitis can range from mild to severe. (healthline.com)
  • Interstitial cystitis shares similar symptoms with endometriosis - especially a type of endometriosis called bladder endometriosis , which occurs in your bladder. (healthline.com)
  • In fact, people with endometriosis may be at an increased risk of developing interstitial cystitis. (healthline.com)
  • Researchers found that people with endometriosis were more than four times as likely to develop interstitial cystitis than people without endometriosis. (healthline.com)
  • Imaging tests such as MRI and transvaginal ultrasound are also sometimes used to help diagnose endometriosis and interstitial cystitis. (healthline.com)
  • Editor's Commentary - Interstitial cystitis/painful bladder syndrome: What do patients mean by "perceived" bladder pain? (urotoday.com)
  • A genome-wide association study for Hunner-type interstitial cystitis led to amino acid variants in the class II human leukocyte antigen DQ-beta1 and DP-beta1 chain genes. (genomeweb.com)
  • Interstitial cystitis, sometimes called bladder pain syndrome (IC/BPS), is a disorder that causes bladder pain and urinary urgency. (lifeextension.com)
  • Figure 1: Hunner lesion observed on the bladder wall of a patient with interstitial cystitis. (lifeextension.com)
  • "Interstitial cystitis" and "bladder pain syndrome" (IC/BPS) are terms used to describe chronic bladder pain or pressure along with urinary symptoms such as urgency, frequency, and sleep disruption due to the need to urinate. (lifeextension.com)
  • Interstitial Cystitis Interstitial cystitis is noninfectious bladder inflammation. (msdmanuals.com)
  • Interstitial cystitis causes pain above the bladder, in the pelvis, or in the lower abdomen, and the frequent and urgent need to. (msdmanuals.com)
  • While the exact cause of feline interstitial cystitis is unknown, stress often plays a large factor. (anasazivet.com)
  • Interstitial cystitis was once thought to be relatively uncommon. (msdmanuals.com)
  • Although men and children can be affected, about 90% of cases of interstitial cystitis occur in women. (msdmanuals.com)
  • Initially, people with interstitial cystitis may have no symptoms. (msdmanuals.com)
  • The diagnosis of interstitial cystitis is suggested by symptoms. (msdmanuals.com)
  • We performed a prospective, single-arm study comparing outcomes between transurethral ablation plus postoperative instillation of hyaluronic acid and chondroitin sulfate (HACS group) and transurethral ablation only in patients with Hunner type interstitial cystitis (historical control group). (bvsalud.org)
  • In patients with Hunner type interstitial cystitis, intravesical instillation of hyaluronic acid and chondroitin sulfate after transurethral ablation significantly reduced the recurrence rate and maintained symptom improvement for more than 1 year. (bvsalud.org)
  • OBJECTIVE: To investigate the efficacy and safety of intravesical instillation of heparin/alkalized lidocaine (lidocaine mixed with sodium bicarbonate) combined with hydrodistension and transurethral fulguration in the treatment of female interstitial cystitis (IC). (bvsalud.org)
  • The patients were evaluated before and 1, 6, and 12 months after treatment for O'Leary-Sant interstitial cystitis patient symptom index scores (ICSI), interstitial cystitis patient problem index scores (ICPI), visual analog scale (VAS) of suprapubic pain, and functional bladder capacity (FBC) changes. (bvsalud.org)
Urethra17
  • The incidence of cystitis is high in women because of the short length of the urethra and because of the proximity of the urethra to the anus. (medscape.com)
  • As cystitis is mostly caused by bacteria from the rectum, movements during sex help move these bacteria up the urethra into the bladder. (mirror.co.uk)
  • The urinary system includes a pair of kidney, ureter, urinary bladder and urethra. (planetayurveda.com)
  • So it is appropriate for the treatment of diseases such as inflammation of the urethra (urethritis), of the bladder (cystitis), urinary tract irritation and acts on the need to urinate repeatedly that these urinary conditions generate. (botanical-online.com)
  • Findings from physical exam and medical history, urine and blood tests, and cystoscopy (a procedure to visualize the inside of the bladder and urethra) are used to rule out other possible causes and check for bladder abnormalities. (lifeextension.com)
  • The tube that carries urine from the bladder out of the body (urethra) contains no bacteria. (msdmanuals.com)
  • If a large amount of tissue is removed or if there is a risk of bleeding after the procedure, a drainage tube (catheter) may be left in the bladder to drain blood and clots and keep them from blocking the urethra. (msdmanuals.com)
  • Urethra: the canal through which urine is discharged from the bladder. (mlnaturals.net)
  • Prostate gland: a partly muscular gland surrounding the urethra at the base of the bladder. (mlnaturals.net)
  • This occurs when bacteria enters into the bladder through the urethra. (lybrate.com)
  • Bacteria in the genital area can enter the urethra and the urinary tract, either because wiping after going to the bathroom, sexual activity, or unsanitary conditions. (healthybladderclub.com)
  • Bacteria from festering waste in the dirty litter box can travel up the urethra, causing a urinary tract infection (UTI) in your cat. (anasazivet.com)
  • The relative shortness of the female urethra (1.2-2 inches in length) makes it easy for bacteria to gain entry to the bladder and multiply. (drmacleods.com.au)
  • Cystoscopy A doctor can diagnose some disorders of the bladder and urethra (for example, bladder tumors, stones in the bladder, benign prostatic enlargement) by looking through a flexible viewing tube. (msdmanuals.com)
  • Normal voiding is essentially a spinal reflex modulated by the central nervous system (brain and spinal cord), which coordinates function of the bladder and urethra. (medscape.com)
  • The bladder and urethra are innervated by 3 sets of peripheral nerves arising from the autonomic nervous system (ANS) and somatic nervous system. (medscape.com)
  • TCC can arise anywhere in the urinary tract, including the renal pelvis, ureter, bladder, and urethra, but it is usually found in the urinary bladder. (medscape.com)
Infections19
Urethritis2
  • Risk factors for acute prostatitis include urethral stricture, lower UTI (cystitis or urethritis), BPH, instrumentation of the lower urinary tract, and prostatic biopsy. (uspharmacist.com)
  • A tea made from the dried leaves is much used for kidney and bladder complaints and inflammations of the urinary tract such as acute and chronic cystitis and urethritis, but it should be used with caution and preferably only under the supervision of a qualified practitioner[4, 21, 46, 172, 222, 254]. (pfaf.org)
Biopsy7
  • The histologic changes identified by means of bladder biopsy support the diagnosis. (medscape.com)
  • Problems may even arise in differentiating malignancy from cystitis with cystoscopy, and biopsy may be required. (medscape.com)
  • Bladder biopsy is done most commonly to diagnose bladder cancer. (msdmanuals.com)
  • Bladder biopsy is usually not done or is done only when using special precautions in people who have bleeding disorders (such as hemophilia). (msdmanuals.com)
  • bladder biopsy usually is not done until after the infection has been treated. (msdmanuals.com)
  • Doctors examine the inside of the bladder with a flexible viewing tube (cystoscopy) and sometimes do a biopsy of the bladder. (msdmanuals.com)
  • Retrospective analysis of the initial bladder biopsy specimen and of 2 lymph nodes taken during abdominal surgery (which became necessary because of a complicating ileal obstruction) confirmed the presence of " M . tilburgii " 16S rRNA gene sequences. (cdc.gov)
Tumors1
  • Bladder tumors may cause mucosal and bladder wall changes that are similar to the changes seen in cystitis, and vice versa. (medscape.com)
Obstruction4
  • However, some clinicians use ultrasonography to exclude secondary causes of cystitis, such as bladder outlet obstruction and bladder calculi. (medscape.com)
  • Bladder Outlet Obstruction: Causes in Men? (medlineplus.gov)
  • Risk factors for chronic prostatitis include anatomical or physiologic lower urinary tract obstruction (i.e., neurologic etiology), voiding dysfunction, pelvic floor muscle dysfunction, intraprostatic reflux of urate and creatinine, BPH, and lower UTI. (uspharmacist.com)
  • The reduction in urine output may be caused by an obstruction in the urinary catheter tubing or deficient fluid volume from blood loss. (nursebuff.com)
Bacteria10
  • As dehydration is one of the factors that leads to cystitis, drinking alcohol can also increase the chances of developing it, while sweating clearly encourages bacteria to grow. (mirror.co.uk)
  • Failing to drink enough water means that urine pH level is altered, and it can lead to bacteria remaining in the bladder. (mirror.co.uk)
  • During intercourse the bacteria enters the bladder via the urinary tract. (planetayurveda.com)
  • Increased numbers of WBCs, RBCs, and/or bacteria are consistent with cystitis. (msdvetmanual.com)
  • Lack of visible bacteria in the sediment does not exclude urinary tract infection. (msdvetmanual.com)
  • One of the more common causes is poor hygiene resulting in urethral contamination with fecal bacteria that then pass directly into the bladder. (uspharmacist.com)
  • Water helps in flushing out the bacteria and other toxins from the bladder, kidneys and the urinary tract. (homeremedieslog.com)
  • Other treatments may include pain relievers, and drinking plenty of water to help wash bacteria out of the urinary tract. (healthybladderclub.com)
  • Urinary Tract Infection (UTI) is a bacterial infection of the urinary system most commonly caused by E. Coli bacteria entering the urinary tract. (drmacleods.com.au)
  • Bacteria were isolated from 19 (24.4%) of 78 urinary stones: 14 were urea splitting and 5 non-urea splitting. (who.int)
Overactive2
Urgency4
  • Patients with bladder cystitis may present with symptoms of urgency, frequency, dysuria, hematuria, cloudy and offensive-smelling urine, or suprapubic discomfort. (medscape.com)
  • The main symptoms are frequent urination, urinary urgency and leakage of urine involuntarily. (homeremedieslog.com)
  • These changes may disrupt barrier function and alter sensory signaling, triggering symptoms including urinary urgency and pain. (lifeextension.com)
  • As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)
Kidneys6
  • A soft massage on the point of kidneys and bladder gives relief from spasm. (homeremedieslog.com)
  • Overview of the Urinary Tract Normally, a person has two kidneys. (msdmanuals.com)
  • It aids in the proper functioning of the bladder, kidneys and prostate - helping to clear up inflammation and infection in these areas, acting as an antimicrobial and antiseptic that also eases venereal diseases. (faithful-to-nature.co.za)
  • Aloe Vera is a powerful laxative and known to be one of the finest body cleansers, removing morbid matter from the stomach, liver, kidneys, spleen and bladder and is considered to be the finest colon cleanser known. (zhealthinfo.com)
  • c) Pyelonephritis - is the infection of the upper urinary tract and kidneys. (drmacleods.com.au)
  • Control of Urination The kidneys constantly produce urine, which flows through 2 tubes (the ureters) to the bladder, where urine is stored (see figure Viewing the Urinary Tract). (msdmanuals.com)
Stones7
  • Bladder stones usually require surgical removal. (maddiesfund.org)
  • A prescription urinary tract diet helps dissolve some kinds of crystals and stones, as well as helping prevent their formation. (maddiesfund.org)
  • Bladder stones form when minerals and organic materials accumulate in the bladder, and are usually the result of inflammation or disease. (anasazivet.com)
  • ABSTRACT Epidemiology and pathogenesis in urinary stones diagnosed in 184 patients were studied. (who.int)
  • Anatomical distribution of urinary stones was 67.4% renal, 12.5% ureteric and 14.6% bladder. (who.int)
  • Urinary stones are the third most common affliction of the urinary tract. (who.int)
  • From December 2001 to September 2002, all 184 patients who were diagnosed by the urologist, or paediatrician in the case of children, as having urinary stones were included in this study. (who.int)
Dysfunction4
  • In the initial state of diabetes, there is Kapha imbalance and with the excessive accumulation of "earth", it disseminates throughout the tissues, which blocks the urinary channels and results in the Vata dysfunction. (planetayurveda.com)
  • C, Skolarikos A. Urofacial syndrome: a subset of neurogenic bladder dysfunction syndromes? (nih.gov)
  • [ 1 ] Neurogenic bladder is a term applied to urinary bladder malfunction due to neurologic dysfunction emanating from internal or external trauma, disease, or injury. (medscape.com)
  • Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. (bvsalud.org)
Urination3
Hematuria1
Neurogenic bladder4
  • symptomatic enlarged prostates (prostatic hypertrophy), bladder control problems ( neurogenic bladder ), narrow-angle glaucoma, and dementia. (nih.gov)
  • nerves that control bladder function (a condition called neurogenic bladder ), liver disease, and joint deformities (contractures). (nih.gov)
  • Symptoms of neurogenic bladder range from detrusor underactivity to overactivity, depending on the site of neurologic insult. (medscape.com)
  • The appropriate therapy for neurogenic bladder and a successful treatment outcome are predicated upon an accurate diagnosis through a careful medical and voiding history, together with a variety of clinical examinations, including urodynamics and selective radiographic imaging studies. (medscape.com)
UTIs1
Urinate2
  • When the bladder muscles get squeezed, there is a sudden and urgent need to urinate. (homeremedieslog.com)
  • Symptoms worsen as the bladder fills and diminish when people urinate. (msdmanuals.com)
Ureters2
  • The rest of the urinary tract consists of the following: Two ureters (the tubes connecting each kidney to the bladder) The bladder (an expandable muscular. (msdmanuals.com)
  • An ileal conduit is a non-continent urinary diversion whereby the ureters drain into an isolated section of ileum. (nursebuff.com)
Chronic cystitis1
Frequent2
Painful2
  • People are being warned of a painful urinary condition that spikes during warm weather with sex and alcohol raising the chances of catching it. (mirror.co.uk)
  • Cystitis can be very painful and lead to a need to go to the toilet with dark urine produced that may also contain traces of blood. (mirror.co.uk)
Cystoscopy1
Pelvic4
  • These endometrial growths are typically found within pelvic structures such as your ovaries, bladder, bowel, and pelvic lining. (healthline.com)
  • A doctor may recommend different tests, including a urinalysis and pelvic exam, to rule out other conditions that can cause similar symptoms, such as bladder inflammation, a urinary tract infection , or another gynecological condition. (healthline.com)
  • Pelvic floor exercises are also useful in getting relief from urinary incontinence. (homeremedieslog.com)
  • Immune system irregularities (eg, autoimmunity, chronic inflammation), undetected chronic infection, inflammation and/or hyperexcitability of the bladder nerves, and altered signaling between the bladder and other pelvic tissues may also contribute. (lifeextension.com)
Benign prostatic h1
Infection and inflammation2
Hunner1
  • 2,5,8 Ulcers on the bladder wall, called Hunner lesions (Figure 1), are present in about 5-10% of cases of IC/BPS, although it is possible that they are under-diagnosed and are present in up to half of all IC/BPS cases. (lifeextension.com)
Dysuria1
Commonly1
  • Bearberry was commonly used by many native North American Indian tribes to treat a wide range of complaints and has also been used in conventional herbal medicine for hundreds of years, it is one of the best natural urinary antiseptics[254]. (pfaf.org)
Acute2
Disorders2
Mucosal1
  • Almost all bladder cancers originate in the urothelium, which is a 3- to 7-cell mucosal layer within the muscular bladder. (medscape.com)
Diseases2
  • Doctors diagnose bladder diseases using different tests. (medlineplus.gov)
  • The leaves were also used in a flushing-out therapy for bacterial and inflammatory diseases of the urinary tract and for kidney gravel. (proliberty.com)
Abdomen4
  • The bladder is a hollow organ in your lower abdomen that stores urine. (medlineplus.gov)
  • They may feel around your abdomen for inflammation or other irregularities. (healthline.com)
  • An animal may exhibit pain on palpation of the caudal abdomen, and the bladder may feel thickened or irregular. (msdvetmanual.com)
  • People have pain or pressure over the bladder or in the pelvis or lower abdomen. (msdmanuals.com)
Cystic1
  • Sagittal and axial scans show a thickened bladder wall and a tubular cystic structure right posterolateral to the urinary bladder (arrowhead). (medscape.com)
Cancer4
  • Bladder cancer is a common urologic cancer that has the highest recurrence rate of any malignancy. (medscape.com)
  • No blood tests are specific for bladder cancer, but a general evaluation is necessary prior to initiating therapy with intravesical bacillus Calmette-Guérin (BCG) vaccine. (medscape.com)
  • The treatment of non-muscle-invasive bladder cancer (Ta, T1, carcinoma in situ [CIS]) begins with transurethral resection of bladder tumor (TURBT). (medscape.com)
  • Bladder cancer is a common urologic cancer. (medscape.com)
Nerves4
  • Electric stimulation relaxes the bladder and calm down the over active nerves that supply urine to the bladder. (homeremedieslog.com)
  • The specialized cells that make up the inner bladder wall are responsible for protecting underlying muscles, nerves, blood vessels, and connective tissue from exposure to excess water, toxins, microbes, and various other compounds present in the urine. (lifeextension.com)
  • They also communicate with sensory nerves within the bladder wall. (lifeextension.com)
  • Stress caused by a dirty litter box can manifest itself as an inflammation of nerves, including those that fill the bladder. (anasazivet.com)
Cells lining the2
  • Changes in the sensory and barrier functions of the cells lining the bladder (Figure 2) are thought to play a role. (lifeextension.com)
  • But doctors think that damage to the cells lining the bladder may allow substances in urine to irritate the bladder. (msdmanuals.com)
Pain4
  • The classic symptoms include urinary frequency and pain above the pubic region. (digitalnaturopath.com)
  • This can result in lower abdominal pain from the bladder, problems urinating due to blood clots , and anemia due to loss of blood. (hdkino.org)
  • Drugs such as anticholinergics used to treat Parkinson's disease, antihistamines, psychotropics, and pain medications can lead to decreased parasympathetic tone and reduced motility and urinary flow. (uspharmacist.com)
  • Inflammation develops in the urinary bladder causing pain. (drnelsonsveterinaryblog.com)
Female urinary1
Treatment4
  • Not only could the toxin point to a possible cause of IC, but also the discovery suggests that bladder growth factor might be used in the treatment of IC. (digitalnaturopath.com)
  • There are many medications and other treatment options that can help and home remedies for bladder spasms are some of the most favorable as they are natural and won'y cause further complications. (homeremedieslog.com)
  • Bladder training is the first and foremost treatment option for spasm control. (homeremedieslog.com)
  • Sometimes doctors use bladder biopsies to assess a person's response to treatment (called surveillance). (msdmanuals.com)
Treatments1
  • There are several home remedies and natural treatments that are very effective for bladder spasms. (homeremedieslog.com)
Healthy bladder2
  • Healthy bladder function is crucial to a person's mobility and overall quality of living. (vitacost.com)
  • Support for healthy bladder function for men and women. (vitacost.com)