• The D2H cDNA is 2284 nucleotides long and encodes a 663 amino acid protein that is 80% identical to the rat D2 amino acid sequence and 86% to that of the rabbit homologue rBAT. (jci.org)
  • Microinjection of in vitro transcribed D2H cRNA into Xenopus oocytes induced uptake of cystine as well as dibasic and neutral amino acids in a pattern similar to that of rat D2 and rabbit rBAT. (jci.org)
  • In 1993, Lee et al cloned a human complementary DNA, rBAT (renal basic amino acid transporter) in chromosome 2, encoding a transport protein for cystine and dibasic amino acids. (medscape.com)
  • Arginine is a basic amino acid as its side chain contains a positively charged guanidinium group, which is highly polar, at the end of a hydrophobic¬†aliphatic¬†hydrocarbon chain. (cannabisdatabase.ca)
  • CoA is essential for the synthesis of phospholipids, fatty acids, polyketides and non-ribosomal peptides, for the operation of the tricarboxylic acid cycle and in the degradation of lipids 3 . (nature.com)
  • Foods and beverages containing other amino acids, such as l-lysine, l-ornithine, and l-cysteine can lead to saturation of the bodies absorption system leading to an excess of unabsorbed amino acids, including the L-Arginine in ProArgi-9 Plus, thereby creating gastrointestinal distress. (complementary-therapists.com)
  • [ 10 ] In 1961, Milne et al demonstrated reduced intestinal absorption of dibasic amino acids in persons with cystinuria. (medscape.com)
  • Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport. (jci.org)
  • We have recently cloned, sequenced, and characterized a rat kidney cDNA (D2) that stimulates cystine as well as dibasic and neutral amino acid transport. (jci.org)
  • Both neutral and dibasic amino acids inhibited the D2H-induced uptake of cystine. (jci.org)
  • Cystinuria is an autosomal-recessive defect in reabsorptive transport of cystine and the dibasic amino acids ornithine, arginine, and lysine from the luminal fluid of the renal proximal tubule and small intestine. (medscape.com)
  • The high-affinity system mediates uptake of 10% of L-cystine and the dibasic amino acids at the apical membrane of the straight third segment (S3) of the proximal tubule. (medscape.com)
  • With a pKa of 12.48, the guanidinium group is positively charged in neutral, acidic, and even most basic environments. (cannabisdatabase.ca)
  • By definition, humic acid is soluble in water at neutral and alkaline pH, but insoluble at acidic pH (wikipedia.org)
  • AIM: To investigate the effect on urine culture results and their clinical interpretation of delaying the processing of urine samples in which boric acid had been used as a preservative. (lookformedical.com)
  • CONCLUSIONS: Boric acid urine preservation used for overnight delayed processing of samples is associated with a significant alteration in culture results and the attendant clinical interpretation of such specimens. (lookformedical.com)
  • Our brains contains transport systems for neutral, dibasic, and dicarboxylic amino acids. (complementary-therapists.com)
  • Various authors have studied amino acid transport in cell membranes obtained from the proximal renal tubule of humans, rats, and rabbits. (medscape.com)
  • The apiofuranosyl residue in each of the two aceric acid-containing side chains is not esterified. (lookformedical.com)
  • Our data provide evidence that the structure of RG-II itself determines which apiofuranosyl residues are esterified with borate and that in the presence of boric acid and certain cations, two RG-II monomers self-assemble to form a dimer. (lookformedical.com)
  • In this report, we present findings on the new kit with regard to reproducibility of the 2-OHE1 and 16alpha-OHE1 measurements, comparability of results with gas chromatography-mass spectroscopy values, and with regard to the stability of the metabolites after repeated freeze-thaw cycles and after preservation by boric acid. (lookformedical.com)
  • The protein encoded by this gene is the light subunit of a cationic amino acid transporter. (nih.gov)
  • This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. (nih.gov)
  • In 1993, Lee et al cloned a human complementary DNA, rBAT (renal basic amino acid transporter) in chromosome 2, encoding a transport protein for cystine and dibasic amino acids. (medscape.com)
  • [ 14 ] The normal SLC7A9 gene encodes a subunit of the cystine transporter called b 0,+ AT (amino acid transporter). (medscape.com)
  • Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. (nih.gov)
  • Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. (nih.gov)
  • The high-affinity system mediates uptake of 10% of L-cystine and the dibasic amino acids at the apical membrane of the straight third segment (S3) of the proximal tubule. (medscape.com)
  • Hymatomelanic acid is part of humic acid that is soluble in ethanol. (wikipedia.org)
  • Administration of hydrochloric acid (HCl) and ethanol produces ulcerative lesions and increases lipid peroxidation in the gastric mucosa, which plays a significant part in the pathogenesis of the mucosal lesion [ 6 ]. (springeropen.com)
  • Humic substances in soils and sediments can be divided into three main fractions: humic acids, fulvic acids, and humin. (wikipedia.org)
  • Probe Set ID Ref Seq Protein ID Signal Strength Name Gene Symbol Species Function Swiss-Prot ID Amino Acid Sequence 1367452_at NP_598278 7.9 small ubiquitin-related modifier 2 precursor Sumo2 Rattus norvegicus " Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. (nih.gov)
  • It is rooted in the history of soil science and, more precisely, in the tradition of alkaline extraction, which dates back to 1786, when Franz Karl Achard treated peat with a solution of potassium hydroxide and, after subsequent addition of an acid, obtained an amorphous dark precipitate (i.e., humic acid). (wikipedia.org)
  • the optical antipode thereof, or the pharmaceutically acceptable acid addition salt thereof, which are useful for treating psychoses, treating depression, treating and alleviating pain, treating hypertension and treating convulsions, alone or in combination with inert adjuvants. (justia.com)