Uptake and biotransformation. Medical search. Frequent questions

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Anatomy9

Microsomes, Liver Liver Bile Hepatocytes Microsomes Feces Intestines Cells, Cultured Kidney

Organisms26

Cunninghamella Gordonia Bacterium Oncorhynchus kisutch Rats, Sprague-Dawley Berberidaceae Hepatophyta Rats, Wistar Dogs Pseudomonas putida Ictaluridae Mucorales Rhodococcus Rats, Inbred F344 Aspergillus ochraceus Nuphar Lactobacillus brevis Photinia Micromonospora Fungi Chlorella Mucor Pseudomonas mendocina Rats, Inbred Strains Rabbits Anemarrhena Streptomyces

Diseases1

Drug-Induced Liver Injury

Chemicals and Drugs127

Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A Ketoconazole Xenobiotics Trichloroethanes Aryl Hydrocarbon Hydroxylases Glucuronosyltransferase Glutathione Transferase Trinitrotoluene Glucuronides Mixed Function Oxygenases Carbon Radioisotopes Oxygenases Cytochrome P-450 CYP1A1 Oxidoreductases, N-Demethylating Troleandomycin Isoenzymes Cytochrome P-450 CYP1A2 Environmental Pollutants Hydrocarbons, Halogenated Toluene Equol Glucuronates Methoxyflurane Nitroglycerin Cytochrome P-450 CYP2E1 Water Pollutants, Chemical Arylamine N-Acetyltransferase Monoterpenes Fenthion Cytochrome P-450 CYP2D6 Benzaldehydes Norisoprenoids Ethylmorphine Pharmaceutical Preparations Prodrugs Cytochrome P-450 CYP2B1 Soil Pollutants Radiopharmaceuticals Coumarins Hydrocarbons, Aromatic Glucose Triazines Hydrocarbons, Chlorinated Isoflavones Eugenol Enzyme Inhibitors 7-Alkoxycoumarin O-Dealkylase Ethyl Ethers Ethylmercuric Chloride Catechols Atrazine Alprazolam Ethoxyquin Ethylmercury Compounds Glutathione Steroid 16-alpha-Hydroxylase Fluorides Coumaric Acids Flame Retardants Phenols Parathion Recombinant Proteins Arsenic tert-Butyl Alcohol Triazolam Acrylonitrile Phenobarbital Umbelliferones Lithocholic Acid Pyrazolones Skin Lightening Preparations Octanes Dichloroethylenes Steroid Hydroxylases Culture Media L-Lysine 6-Transaminase Carboxylesterase Polycyclic Hydrocarbons, Aromatic Carcinogens Benzo(a)pyrene NADPH-Ferrihemoprotein Reductase Butylene Glycols Deoxyglucose Zearalenone Mutagens Dichloroacetic Acid Mercury Compounds Fluorodeoxyglucose F18 Norbornanes Aminophenols Iodine Radioisotopes Fluorenes Aldehyde Dehydrogenase Tritium Guaiacol Halothane Xylenes Pyrrolizidine Alkaloids Estrogens, Non-Steroidal Epoxide Hydrolases Trifluoroacetic Acid Esters Hydrocarbons, Fluorinated Amines Safrole Antimitotic Agents Aflatoxin B1 Alkanes Transaldolase Chenodeoxycholic Acid Fluorine Fungicides, Industrial Styrenes Sulfotransferases Trichloroethylene Nitro Compounds Terpenes Polychlorinated Biphenyls Polycyclic Compounds Phenanthrenes Methyl Ethers Ochratoxins Aniline Hydroxylase Ursodeoxycholic Acid Lactones Benzene Derivatives

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Chromatography, High Pressure Liquid Mass Spectrometry Gas Chromatography-Mass Spectrometry Magnetic Resonance Spectroscopy Chromatography, Liquid Tandem Mass Spectrometry Administration, Oral Metabolic Clearance Rate Spectrometry, Mass, Electrospray Ionization Metabolic Engineering Spectrophotometry, Ultraviolet Batch Cell Culture Techniques Culture Media Chromatography, Thin Layer Anesthesia, Inhalation Models, Biological Positron-Emission Tomography Mutagenicity Tests Bioreactors Toxicity Tests

Phenomena and Processes27

Biotransformation Dealkylation Hydroxylation Metabolic Detoxication, Phase I Biological Transport Kinetics Metabolic Detoxication, Phase II Oxidation-Reduction Stereoisomerism Molecular Structure Metabolic Detoxication, Drug Tissue Distribution Species Specificity Half-Life Drug Interactions Time Factors Metabolic Clearance Rate Biological Transport, Active Enzyme Induction Dose-Response Relationship, Drug Intestinal Absorption Hydrogen-Ion Concentration Metabolic Networks and Pathways Biocatalysis Substrate Specificity Biological Availability Halogenation

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Safety-Based Drug Withdrawals

Technology, Industry, Agriculture4

Metabolic Engineering Skin Lightening Preparations Biotechnology Bioreactors

Information Science1

Molecular Sequence Data

Health Care2

Biodegradation, Environmental Safety-Based Drug Withdrawals

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Technology, Industry, Agriculture Information Science Health Care

Biotransformation Cunninghamella Microsomes, Liver Cytochrome P-450 Enzyme System Chromatography, High Pressure Liquid Dealkylation Hydroxylation Cytochrome P-450 CYP3A Metabolic Detoxication, Phase I Ketoconazole Biodegradation, Environmental Xenobiotics Liver Biological Transport Trichloroethanes Mass Spectrometry Aryl Hydrocarbon Hydroxylases Glucuronosyltransferase Kinetics Metabolic Detoxication, Phase II Glutathione Transferase Oxidation-Reduction Stereoisomerism Trinitrotoluene Molecular Structure Glucuronides Gas Chromatography-Mass Spectrometry Mixed Function Oxygenases Metabolic Detoxication, Drug Carbon Radioisotopes Magnetic Resonance Spectroscopy Gordonia Bacterium Oxygenases Bile Cytochrome P-450 CYP1A1 Tissue Distribution Oxidoreductases, N-Demethylating Troleandomycin Isoenzymes Species Specificity Oncorhynchus kisutch Cytochrome P-450 CYP1A2 Environmental Pollutants Hepatocytes Half-Life Hydrocarbons, Halogenated Chromatography, Liquid Microsomes Toluene Drug Interactions Equol Glucuronates Methoxyflurane Rats, Sprague-Dawley Nitroglycerin Feces Berberidaceae Cytochrome P-450 CYP2E1 Water Pollutants, Chemical Arylamine N-Acetyltransferase Monoterpenes Fenthion Cytochrome P-450 CYP2D6 Hepatophyta Benzaldehydes Norisoprenoids Tandem Mass Spectrometry Ethylmorphine Pharmaceutical Preparations Prodrugs Administration, Oral Cytochrome P-450 CYP2B1 Time Factors Soil Pollutants Rats, Wistar Dogs Metabolic Clearance Rate Radiopharmaceuticals Pseudomonas putida Ictaluridae Mucorales Coumarins Hydrocarbons, Aromatic Glucose Triazines Hydrocarbons, Chlorinated Isoflavones Eugenol Enzyme Inhibitors 7-Alkoxycoumarin O-Dealkylase Ethyl Ethers Rhodococcus Ethylmercuric Chloride Catechols Spectrometry, Mass, Electrospray Ionization Atrazine Biological Transport, Active Rats, Inbred F344 Enzyme Induction Alprazolam

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