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  • proximal
  • Furthermore, electron microscopy experiments demonstrated that when Rep is bound to an upstream Rep binding element, it can interact with a proximal Sp1 site by protein contacts and create a loop in the intervening DNA. (biomedsearch.com)
  • chromatin
  • Studies in Drosophila and vertebrate systems have revealed several important chromatin barrier elements and their respective binding factors. (ufl.edu)
  • However, epigenomic data indicate that the binding of these factors are not exclusive to chromatin boundaries. (ufl.edu)
  • calcium
  • In addition, bone is an endocrine organ that produces hormones and serves as a target organ for paracrine and endocrine factors that control calcium and phosphate homeostasis. (jimmunol.org)
  • cells
  • We previously identified an E-box to be implicated in high-glucose-induced transforming growth factor-beta1 (TGF-beta1) gene stimulation in murine mesangial cells. (semanticscholar.org)
  • Cells of the osteoclastic and osteoblastic lineages communicate through cell-to-cell contact and paracrine factors in a bidirectional fashion. (jimmunol.org)
  • response
  • Maternal obesity is associated with ovarian inflammation and upregulation of early growth response factor 1. (abcam.com)