Upregulation tumor suppressor protein p53. Medical search. Frequent questions

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Anatomy16

Cell Line, Tumor Cell Line Tumor Cells, Cultured Fibroblasts HeLa Cells Cells, Cultured Cell Nucleus HCT116 Cells Cell Line, Transformed COS Cells NIH 3T3 Cells Cytoplasm Epithelial Cells HEK293 Cells 3T3 Cells Keratinocytes

Organisms8

Spodoptera Mice, Knockout Papillomaviridae Mice, Inbred C57BL Mice, Nude Mice, Transgenic Mice, Inbred BALB C Adenoviridae

Diseases28

Neoplasms Cell Transformation, Neoplastic Kidney Neoplasms Breast Neoplasms Wilms Tumor Osteosarcoma Carcinoma, Renal Cell Neoplasms, Experimental Neurofibromatosis 2 Adenocarcinoma von Hippel-Lindau Disease Liver Neoplasms Colonic Neoplasms Brain Neoplasms Carcinoma, Hepatocellular Carcinoma, Squamous Cell Retinoblastoma Skin Neoplasms Disease Progression Lung Neoplasms Neoplasm Metastasis Disease Models, Animal Glioblastoma Carcinoid Tumor Neovascularization, Pathologic Mammary Neoplasms, Experimental Ovarian Neoplasms Neuroendocrine Tumors

Chemicals and Drugs98

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Proto-Oncogene Proteins c-mdm2 Von Hippel-Lindau Tumor Suppressor Protein Cyclin-Dependent Kinase Inhibitor p21 Tumor Suppressor Protein p14ARF Nuclear Proteins Cyclins Retinoblastoma Protein DNA-Binding Proteins Proto-Oncogene Proteins Transcription Factors Cell Cycle Proteins Ubiquitin-Protein Ligases RNA, Messenger Oncogene Proteins, Viral Adenovirus E1B Proteins Ubiquitins DNA Neurofibromin 2 Adenomatous Polyposis Coli Protein bcl-2-Associated X Protein Antigens, Polyomavirus Transforming Recombinant Fusion Proteins Proteasome Endopeptidase Complex Cyclin-Dependent Kinase Inhibitor p16 Trans-Activators DNA Primers PTEN Phosphohydrolase Recombinant Proteins Proto-Oncogene Proteins c-bcl-2 Neoplasm Proteins RNA, Small Interfering E2F Transcription Factors Repressor Proteins Protein-Serine-Threonine Kinases Proteins Ligases Serine Tumor Markers, Biological Retinoblastoma-Like Protein p107 Carrier Proteins E2F1 Transcription Factor Retinoblastoma-Like Protein p130 Transcription Factor DP1 Suppressor of Cytokine Signaling Proteins Papillomavirus E7 Proteins Retinoblastoma-Binding Protein 1 Tumor Necrosis Factor-alpha WT1 Proteins Membrane Proteins Phosphoproteins Hypoxia-Inducible Factor 1, alpha Subunit Cyclin-Dependent Kinases DNA, Neoplasm Intracellular Signaling Peptides and Proteins Ubiquitin Apoptosis Regulatory Proteins Phosphoric Monoester Hydrolases Adenovirus E1A Proteins Cytoskeletal Proteins Adaptor Proteins, Signal Transducing beta Catenin Drosophila Proteins Neurofibromin 1 Cyclin-Dependent Kinase Inhibitor p27 BRCA1 Protein DNA, Complementary Luciferases Proto-Oncogene Proteins c-myc MicroRNAs Antineoplastic Agents Cyclin-Dependent Kinase 4 Protein Isoforms Suppressor Factors, Immunologic RNA, Neoplasm Oncogene Proteins Adenovirus E4 Proteins Hypoxia-Inducible Factor 1 Enzyme Inhibitors Proto-Oncogene Proteins c-akt Cyclin D1 Cyclin-Dependent Kinase 2 Viral Proteins Multiprotein Complexes Cysteine Endopeptidases Glutathione Transferase Protein Kinases Multienzyme Complexes Cadherins Ubiquitin Thiolesterase CDC2-CDC28 Kinases Microtubule-Associated Proteins NF-kappa B Antibodies, Monoclonal Proliferating Cell Nuclear Antigen Histones RNA-Binding Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Transfection Blotting, Western Precipitin Tests Models, Biological Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Tumor Burden Immunoblotting Polymerase Chain Reaction Immunoprecipitation Transplantation, Heterologous Neoplasms, Experimental Gene Expression Profiling Flow Cytometry Two-Hybrid System Techniques Cloning, Molecular Microscopy, Fluorescence Chromatin Immunoprecipitation Oligonucleotide Array Sequence Analysis Disease Models, Animal Fluorescent Antibody Technique Neoplasm Transplantation DNA Mutational Analysis Chromosome Mapping Xenograft Model Antitumor Assays Mammary Neoplasms, Experimental Blotting, Northern Sequence Alignment Mutagenesis, Site-Directed Immunoenzyme Techniques

Phenomena and Processes74

Genes, Tumor Suppressor Apoptosis Protein Binding Genes, p53 Transfection Mutation DNA Damage Transcriptional Activation Cell Cycle Base Sequence Promoter Regions, Genetic Amino Acid Sequence Gene Expression Regulation, Neoplastic Transcription, Genetic Phosphorylation Binding Sites Cell Proliferation Signal Transduction Down-Regulation Protein Structure, Tertiary Cell Division Gene Expression Regulation Ultraviolet Rays Consensus Sequence Genes, Suppressor Up-Regulation Cell Survival Acetylation Gene Silencing RNA Interference DNA Methylation Suppression, Genetic Gene Deletion Loss of Heterozygosity Protein Conformation G1 Phase Cell Aging Gene Expression Genes, Retinoblastoma Genes, Neurofibromatosis 2 Phenotype Oncogenes Time Factors Sequence Homology, Amino Acid Genes, Reporter Ubiquitination Cell Movement Plasmids Cell Differentiation Genes, APC Sequence Deletion S Phase Genes, p16 Enzyme Activation Genes, ras Amino Acid Motifs Active Transport, Cell Nucleus Gamma Rays Protein Stability Alleles Protein Transport Genes, Wilms Tumor Cell Hypoxia Genetic Vectors Protein Processing, Post-Translational Mutagenesis Point Mutation DNA Repair Tumor Microenvironment Exons Dose-Response Relationship, Drug Cell Death CpG Islands Cell Cycle Checkpoints

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Proto-Oncogene Proteins c-mdm2 Von Hippel-Lindau Tumor Suppressor Protein Cyclin-Dependent Kinase Inhibitor p21 Cell Line, Tumor Apoptosis Tumor Suppressor Protein p14ARF Protein Binding Genes, p53 Nuclear Proteins Cell Line Molecular Sequence Data Cyclins Retinoblastoma Protein Transfection Mutation DNA-Binding Proteins Tumor Cells, Cultured Proto-Oncogene Proteins DNA Damage Transcriptional Activation Cell Cycle Base Sequence Promoter Regions, Genetic Amino Acid Sequence Transcription Factors Gene Expression Regulation, Neoplastic Transcription, Genetic Phosphorylation Cell Cycle Proteins Ubiquitin-Protein Ligases Binding Sites Cell Proliferation Signal Transduction RNA, Messenger Down-Regulation Blotting, Western Oncogene Proteins, Viral Protein Structure, Tertiary Adenovirus E1B Proteins Cell Division Gene Expression Regulation Fibroblasts HeLa Cells Cells, Cultured Ultraviolet Rays Ubiquitins DNA Neurofibromin 2 Neoplasms Adenomatous Polyposis Coli Protein bcl-2-Associated X Protein Antigens, Polyomavirus Transforming Recombinant Fusion Proteins Proteasome Endopeptidase Complex Cyclin-Dependent Kinase Inhibitor p16 Precipitin Tests Consensus Sequence Cell Nucleus Trans-Activators DNA Primers Spodoptera Genes, Suppressor PTEN Phosphohydrolase Cell Transformation, Neoplastic Up-Regulation Recombinant Proteins Mice, Knockout Proto-Oncogene Proteins c-bcl-2 Neoplasm Proteins Cell Survival RNA, Small Interfering Acetylation E2F Transcription Factors Papillomaviridae Repressor Proteins Protein-Serine-Threonine Kinases Models, Biological Proteins Ligases Serine Reverse Transcriptase Polymerase Chain Reaction Tumor Markers, Biological Retinoblastoma-Like Protein p107 Carrier Proteins Gene Silencing RNA Interference E2F1 Transcription Factor Retinoblastoma-Like Protein p130 Transcription Factor DP1 Suppressor of Cytokine Signaling Proteins DNA Methylation Suppression, Genetic Immunohistochemistry Papillomavirus E7 Proteins Gene Deletion Retinoblastoma-Binding Protein 1 Loss of Heterozygosity

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