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  • NMDP
  • If you were matched to a donor or patient registered with the NMDP, contact will be facilitated by the registry and transplant center no sooner than one year after the transplant. (fredhutch.org)
  • Rules regarding contact may differ for donors registered though other organizations, even if the match was facilitated through the NMDP. (fredhutch.org)
  • Within the NMDP registry, the probability of identifying at least one antigen level-matched (HLA-A and -B) and potential allele level-matched (HLA-DRB1) donor depends upon race/ethnicity. (psychiatryadvisor.com)
  • Most donors in the registry are partially matched at HLA A and B. The HapLogic algorithm in the NMDP utilizes extended HLA typing for haplotype analysis to predict the donor's DRB1 type and narrow the list of potential unrelated donors. (psychiatryadvisor.com)
  • engraftment
  • 2 ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ - 16 The benefit is primarily derived from the replacement of missing enzyme produced by donor cells circulating in the blood and also from engraftment of donor-derived glial cells in the brain. (bloodjournal.org)
  • proteins
  • Matching a patient to a bone marrow/stem cell donor relies on testing of specific proteins on the surface of white blood cells called human leukocyte antigens (HLA). (fredhutch.org)
  • HLA-identical siblings or HLA-identical unrelated donors often have genetically different proteins (called minor histocompatibility antigens) that can be presented by Major histocompatibility complex (MHC) molecules to the donor's T-cells, which see these antigens as foreign and so mount an immune response. (wikipedia.org)
  • Study
  • The Effect of Aging and Pre-Donation Comorbidities on the Related PBSC Donor Experience: A Report from the Related Donor Safety Study (RDSafe). (bioportfolio.com)
  • In this study we analyzed 522 unrelated donor-patient pairs and examined the combined effect of all the common polymorphisms in this genomic region. (haematologica.org)
  • Factors
  • Factors predicting peripheral blood progenitor cell mobilization in healthy donors in the era of related alternative donors: Experience from a single center. (bioportfolio.com)
  • Factors predicting CD34+-cell yield after mobilization in related alternative donors are still poorly known. (bioportfolio.com)
  • blood
  • The donor will be invited to the nearest donor center and, after testing and consenting, will undergo either a marrow harvest or G-CSF (granulocyte colony-stimulating factor) mobilized peripheral blood collection by apheresis. (psychiatryadvisor.com)
  • important
  • Obviously, registering to become a donor is an important and serious decision to make, but they're short on donors of people not of white/European descent. (slashdot.org)