• UniProt Knowledgebase (UniProtKB) is a protein database partially curated by experts, consisting of two sections: UniProtKB/Swiss-Prot (containing reviewed, manually annotated entries) and UniProtKB/TrEMBL (containing unreviewed, automatically annotated entries). (wikipedia.org)
  • The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). (vifabio.de)
  • UniProt provides four core databases: UniProtKB (with sub-parts Swiss-Prot and TrEMBL), UniParc, UniRef and Proteome. (wikipedia.org)
  • UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. (wikipedia.org)
  • Database against which the search is performed: UniProtKB or clusters of sequences with 100%, 90% or 50% identity. (biocode.ltd)
  • You can also map the results to UniProt protein databases UniProtKB, UniRef and UniParc. (biocode.ltd)
  • Swiss-Prot aimed to provide reliable protein sequences associated with a high level of annotation (such as the description of the function of a protein, its domain structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. (wikipedia.org)
  • Meanwhile, PIR maintained the PIR-PSD and related databases, including iProClass, a database of protein sequences and curated families. (wikipedia.org)
  • Sequences from the same gene and the same species are merged into the same database entry. (wikipedia.org)
  • Align two or more protein sequences on the UniProt web site using ClustalOmega. (expasy.org)
  • This track shows protein sequences and annotations on them from the UniProt/SwissProt database, mapped to genomic coordinates. (ucsc.edu)
  • Differences between Genbank sequences and the UniProt sequence. (ucsc.edu)
  • Low-complexity regions (e.g. stretches of cysteine in Q03751 , or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. (biocode.ltd)
  • In this activity, students access a database called UniProt that provides information about protein sequences derived from genome sequencing. (biologycorner.com)
  • The UniProt Metagenomic and Environmental Sequences (UniMES) database is a repository specifically developed for metagenomic and environmental data. (vifabio.de)
  • Until recently, EBI and SIB together produced the Swiss-Prot and TrEMBL databases, while PIR produced the Protein Sequence Database (PIR-PSD). (wikipedia.org)
  • UniProt/SwissProt data has been curated from scientific publications by the UniProt staff, UniProt/TrEMBL data has been predicted by various computational algorithms. (ucsc.edu)
  • Starting 2003, UniProt unites several resources of the consortium members, such as the Swiss-Prot and TrEMBL databases, and the Protein Sequence Database (PIR-PSD). (vifabio.de)
  • UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. (wikipedia.org)
  • PIR, hosted by the National Biomedical Research Foundation (NBRF) at the Georgetown University Medical Center in Washington, DC, US, is heir to the oldest protein sequence database, Margaret Dayhoff's Atlas of Protein Sequence and Structure, first published in 1965. (wikipedia.org)
  • These databases coexisted with differing protein sequence coverage and annotation priorities. (wikipedia.org)
  • Enter either a protein or nucleotide sequence (raw sequence or fasta format) or a UniProt identifier into the form field. (biocode.ltd)
  • Enter either a protein or nucleotide sequence or a UniProt identifier into the form field (Figure 37). (biocode.ltd)
  • The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. (vifabio.de)
  • Each consortium member is heavily involved in protein database maintenance and annotation. (wikipedia.org)
  • For consistency and convenience for users of mutation-related tracks, the subtrack 'UniProt/SwissProt Variants' is a copy of the track 'UniProt Variants' in the track group 'Phenotype and Literature', or 'Variation and Repeats', depending on the assembly. (ucsc.edu)
  • It is maintained by the UniProt consortium, which consists of several European bioinformatics organisations and a foundation from Washington, DC, United States. (wikipedia.org)
  • The UniProt consortium comprises the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). (wikipedia.org)
  • EBI, located at the Wellcome Trust Genome Campus in Hinxton, UK, hosts a large resource of bioinformatics databases and services. (wikipedia.org)
  • UniProt is a collaboration between the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR). (vifabio.de)
  • 5. Immunological bioinformatics analysis tools (IEDB) and database search (UniPROT). (helsinki.fi)
  • There are two types of biological databases. (iucr.org)
  • Blast searches can be run directly from the 'Blast' button in UniProt entry pages. (biocode.ltd)
  • Please upgrade your browser to a newer version to get the best experience on Human Metabolome Database. (hmdb.ca)
  • We teach the use of UniProt, the RCSB Protein Data Bank, PubMed, OMIM and PubChem for students to find information, while using the Open Science Framework and Zotero to aid students in managing their research activities. (asbmb.org)
  • Database analyses retrieved 40 active ingredients and 47 target genes in SHD. (hindawi.com)
  • For example, students might use PubMed to search literature while exploring the diverse scientists in the biochemical field, or they extrapolate mutation data from Uniprot to explain the molecular basis for disease. (asbmb.org)
  • The TCMSP database and PubChem were applied to retrieve the main chemical components of SHD, and the ACD/Labs software and the SwissADME online system were utilized for ADMET screening. (hindawi.com)
  • The consortium members pooled their overlapping resources and expertise, and launched UniProt in December 2003. (wikipedia.org)
  • Repositories, archives or deposition databases collect primary ( i.e. experimental) data. (iucr.org)
  • Here, an overview of the publicly available knowledge about IDRs is reported, including manually curated resources, deposition databases and prediction repositories. (iucr.org)
  • Databases provide sustained access to material resources, facilitating their reuse, and are essential for re-analysis, validation and testing of new hypotheses. (iucr.org)
  • Sometimes resources are of both types, and the majority of deposition databases also process data to facilitate visualization. (iucr.org)
  • We provide an online database of annotated PPI predictions ( http://ophid.utoronto.ca/fpclass/ ) and the prediction software ( http://www.cs.utoronto.ca/~juris/data/fpclass/ ). (nature.com)
  • SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases. (wikipedia.org)
  • An enal that consists of 3,7-dimethyl-9-nona-2,4,6,8-tetraenal (double bond geometry unspecified) carrying a 2,6,6-trimethylcyclohex-1-en-1-yl group at the 9-position. (ebi.ac.uk)
  • Across the three institutes close to 150 people are involved through different tasks such as database curation, software development and support. (vifabio.de)
  • Data were acquired using unbiased data-independent mass spectrometry (MS). Statistically significant and measures were processed in ProteinLynx Global Server and sequenced using in-house software EndogeSeq against selective subsets of a mouse UniProt protein database. (cdc.gov)
  • The annotations are divided into multiple subtracks, based on their 'feature type' in UniProt. (ucsc.edu)
  • Relevant publications are identified by searching databases such as PubMed. (wikipedia.org)
  • Expert biocurators play a crucial role in IDP databases by providing a direct interpretation of disorder derived from structural experiments and manually curating these ID annotations. (iucr.org)
  • We have found that some students are more accustomed to searching in Google with natural language than in a research database using keywords. (asbmb.org)