Understanding protein stability. Medical search. Frequent questions

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Cell Line HEK293 Cells Cell Line, Tumor HeLa Cells COS Cells Cells, Cultured Cell Nucleus NIH 3T3 Cells Cytoplasm Fibroblasts Cell Membrane Tumor Cells, Cultured

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Escherichia coli Saccharomyces cerevisiae Cercopithecus aethiops Bacteriophage T4 Mice, Knockout Mice, Inbred C57BL Cattle Cricetinae Arabidopsis

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Genomic Instability Neoplasms

Chemicals and Drugs92

Proteins Proteasome Endopeptidase Complex Ubiquitin Guanidine Ubiquitin-Protein Ligases RNA, Messenger Urea Recombinant Proteins Solvents Muramidase Transcription Factors Mutant Proteins DNA-Binding Proteins Bacterial Proteins Nuclear Proteins Recombinant Fusion Proteins Tumor Suppressor Protein p53 Leupeptins Amino Acids Proto-Oncogene Proteins c-mdm2 Salts Multiprotein Complexes RNA, Small Interfering Carrier Proteins Membrane Proteins Lysine Proteasome Inhibitors Water DNA Serine Tumor Suppressor Proteins DNA Primers Solutions F-Box Proteins Cell Cycle Proteins Protein-Serine-Threonine Kinases Repressor Proteins Cysteine Disulfides Peptides Ribonucleases Glycogen Synthase Kinase 3 Complex Mixtures Lactalbumin Proto-Oncogene Proteins c-myc Peptidylprolyl Isomerase Cullin Proteins Protein Isoforms Hypoxia-Inducible Factor 1, alpha Subunit Ligands SUMO-1 Protein Apoproteins Trans-Activators Saccharomyces cerevisiae Proteins Molecular Chaperones Plant Proteins Proline Alanine Ubiquitins HSP90 Heat-Shock Proteins RNA-Binding Proteins Protein Subunits Ubiquitin-Specific Proteases Tryptophan Micrococcal Nuclease SKP Cullin F-Box Protein Ligases Escherichia coli Proteins Multienzyme Complexes Green Fluorescent Proteins Intracellular Signaling Peptides and Proteins Ribonuclease T1 Histidine Peptide Hydrolases RNA Cysteine Endopeptidases Arabidopsis Proteins Proto-Oncogene Proteins Small Ubiquitin-Related Modifier Proteins Methylamines Thermolysin Drosophila Proteins Adaptor Proteins, Signal Transducing Protein Synthesis Inhibitors beta-Transducin Repeat-Containing Proteins Threonine Hypoxia-Inducible Factor-Proline Dioxygenases Anilino Naphthalenesulfonates Cycloheximide Endopeptidases Cyclin-Dependent Kinase Inhibitor p21 PTEN Phosphohydrolase Chymotrypsinogen

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Sequence Analysis, Protein Models, Molecular Enzyme Stability Drug Stability Protein Denaturation Circular Dichroism Amino Acid Substitution Protein Engineering Mutagenesis, Site-Directed Protein Unfolding Models, Biological Calorimetry, Differential Scanning Models, Chemical Crystallography, X-Ray Sequence Alignment Spectrometry, Fluorescence Transfection Blotting, Western Immunoprecipitation Molecular Dynamics Simulation Calorimetry Nuclear Magnetic Resonance, Biomolecular Two-Hybrid System Techniques Magnetic Resonance Spectroscopy Reverse Transcriptase Polymerase Chain Reaction Immunoblotting Protein Interaction Mapping Models, Genetic Cloning, Molecular Microscopy, Fluorescence Gene Knockdown Techniques Spectrophotometry, Ultraviolet Electrophoresis, Polyacrylamide Gel Drug Storage Mass Spectrometry Polymerase Chain Reaction Gene Expression Profiling DNA Mutational Analysis Precipitin Tests Directed Molecular Evolution

Psychiatry and Psychology1

Phenomena and Processes95

Protein Stability Protein Folding Protein Conformation Algorithms Protein Binding Enzyme Stability Protein Denaturation Thermodynamics Mutation RNA Stability Amino Acid Sequence Protein Structure, Tertiary Ubiquitination Temperature Protein Structure, Secondary Proteolysis Amino Acid Substitution Protein Unfolding Kinetics Base Sequence Signal Transduction Hot Temperature Protein Processing, Post-Translational Binding Sites Half-Life Hydrogen Bonding Phosphorylation Structure-Activity Relationship Gene Expression Regulation Hydrogen-Ion Concentration Transcription, Genetic Static Electricity Mutation, Missense Transition Temperature Amino Acid Motifs Time Factors Hydrophobic and Hydrophilic Interactions Sequence Homology, Amino Acid Transfection Phenotype Protein Structure, Quaternary Point Mutation Protein Multimerization Plasmids Protein Transport Solubility Dimerization Molecular Dynamics Simulation Entropy Sumoylation Protein Biosynthesis Down-Regulation Evolution, Molecular Mutagenesis Cell Cycle Protein Interaction Domains and Motifs Conserved Sequence RNA Interference Molecular Structure Cell Proliferation Apoptosis Gene Expression Promoter Regions, Genetic Catalytic Domain Genomic Instability Sequence Deletion Substrate Specificity DNA Damage Transcriptional Activation Physicochemical Phenomena Surface Properties Catalysis Molecular Conformation Acetylation Glycosylation RNA Processing, Post-Transcriptional Fluorescence Genetic Variation Gene Expression Regulation, Neoplastic Up-Regulation Species Specificity Genes, Reporter Cell Differentiation Oxidation-Reduction Active Transport, Cell Nucleus Gene Deletion Gene Expression Regulation, Enzymologic Phylogeny Nucleic Acid Conformation Cell Survival Biomechanical Phenomena Osmolar Concentration Hydrolysis Biophysical Phenomena Enzyme Activation

Disciplines and Occupations3

Computational Biology Chemistry, Physical Biophysics

Information Science9

Databases, Protein Algorithms Software Molecular Sequence Data Amino Acid Sequence Base Sequence Computer Simulation Molecular Dynamics Simulation Phylogeny

Health Care2

Temperature Hot Temperature

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Protein Stability Proteins Sequence Analysis, Protein Protein Folding Models, Molecular Protein Conformation Databases, Protein Algorithms Computational Biology Protein Binding Enzyme Stability Software Drug Stability Protein Denaturation Thermodynamics Molecular Sequence Data Mutation RNA Stability Amino Acid Sequence Protein Structure, Tertiary Ubiquitination Temperature Protein Structure, Secondary Circular Dichroism Proteasome Endopeptidase Complex Proteolysis Ubiquitin Amino Acid Substitution Protein Engineering Guanidine Cell Line Mutagenesis, Site-Directed Protein Unfolding Models, Biological Ubiquitin-Protein Ligases Kinetics Base Sequence Calorimetry, Differential Scanning Signal Transduction Hot Temperature RNA, Messenger Protein Processing, Post-Translational Binding Sites Half-Life HEK293 Cells Urea Hydrogen Bonding Phosphorylation Recombinant Proteins Escherichia coli Models, Chemical Computer Simulation Structure-Activity Relationship Cell Line, Tumor Gene Expression Regulation Hydrogen-Ion Concentration Solvents Muramidase Transcription, Genetic Transcription Factors Static Electricity Mutation, Missense Mutant Proteins DNA-Binding Proteins Crystallography, X-Ray Transition Temperature Amino Acid Motifs Bacterial Proteins Nuclear Proteins Time Factors Hydrophobic and Hydrophilic Interactions Sequence Alignment Recombinant Fusion Proteins Sequence Homology, Amino Acid Spectrometry, Fluorescence Tumor Suppressor Protein p53 HeLa Cells Transfection Leupeptins Phenotype Amino Acids COS Cells Protein Structure, Quaternary Cells, Cultured Proto-Oncogene Proteins c-mdm2 Point Mutation Protein Multimerization Salts Multiprotein Complexes Blotting, Western Plasmids RNA, Small Interfering Carrier Proteins Membrane Proteins Protein Transport Lysine Immunoprecipitation Saccharomyces cerevisiae Solubility Proteasome Inhibitors

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