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  • patients
  • Across 4 sites, 178 pediatric patients scheduled to undergo SCT were randomized to a child-targeted intervention involving massage and humor therapy (HPI-C), the identical child intervention plus a parent intervention involving massage and relaxation/imagery (HPI-CP) or standard care (SC). (pubmedcentralcanada.ca)
  • Arm I: Beginning immediately after the development of mucositis pain, patients undergo acupuncture over 30 minutes once daily. (knowcancer.com)
  • Arm II: Patients undergo placebo acupuncture and receive standard pain management as in arm I. (knowcancer.com)
  • The nuclei are usually round to oval in shape, with occasional patients having cells with a more irregular nuclear outline that is similar to the cerebriform nuclear shape seen in Sézary syndrome. (wikipedia.org)
  • Most patients with T-cell prolymphocytic leukemia require immediate treatment. (wikipedia.org)
  • neural stem
  • Conclusions reached from these studies have directed attention to specific signaling molecules and effector pathways that are responsible for mediating the cellular events required for maintaining or changing the neural stem cell fate. (wikipedia.org)
  • This complicates the design of drugs, for instance neural stem cell targeted therapies for the treatment of clinical depression. (wikipedia.org)
  • genome
  • Thus, different cells can have very different physical characteristics despite having the same genome. (wikipedia.org)
  • Each of the approximately 100 trillion (1014) cells in an adult human has its own copy or copies of the genome except certain cell types, such as red blood cells, that lack nuclei in their fully differentiated state. (wikipedia.org)
  • lineages
  • Glial cell-derived astrocytes are specialized lineages responsible for modulating the chemical environment by altering ion gradients and neurotransmitter transduction. (wikipedia.org)
  • Functions of glial-derived cell lineages are reviewed by Baumann and Hauw. (wikipedia.org)
  • Gene expression at these histones regulated by epigenetic modifications is critical in restricting the embryonic stem cell to desired cell lineages and developing cellular memory. (wikipedia.org)
  • cycles of cell division
  • In humans, approximately four days after fertilization and after several cycles of cell division, these cells begin to specialize, forming a hollow sphere of cells, called a blastocyst. (wikipedia.org)
  • A stem cell possesses two properties: Self-renewal, which is the ability to go through numerous cycles of cell division while still maintaining its undifferentiated state. (wikipedia.org)
  • vitro
  • These properties can be illustrated with relative ease in vitro, using methods such as clonogenic assays, where the progeny of a single cell is characterized. (wikipedia.org)
  • It can be induced by modifying the growth medium when stem cells are cultured in vitro or transplanting them to an organ of the body different from the one they were originally isolated from. (wikipedia.org)
  • 2007 Nov;73:1106-10) and "very small embryonic like" - "VSEL" stem cells, and display pluripotency in vitro. (wikipedia.org)
  • lymphocytic leukemias
  • This divides leukemias into lymphoblastic or lymphocytic leukemias and myeloid or myelogenous leukemias: In lymphoblastic or lymphocytic leukemias, the cancerous change takes place in a type of marrow cell that normally goes on to form lymphocytes, which are infection-fighting immune system cells. (wikipedia.org)
  • Most lymphocytic leukemias involve a specific subtype of lymphocyte, the B cell. (wikipedia.org)
  • humans
  • It's controversial not only because the stem cells are from human embryos but because critics think the research hasn't progressed enough to test on humans. (newser.com)
  • germ
  • Germ line cells are any line of cells that give rise to gametes-eggs and sperm-and thus are continuous through the generations. (wikipedia.org)
  • burden
  • Of all herpes viruses, HCMV harbors the most genes dedicated to altering (evading) innate and adaptive immunity in the host and represents a lifelong burden of antigenic T cell surveillance and immune dysfunction. (wikipedia.org)
  • leukemia
  • Other names include T-cell chronic lymphocytic leukemia, "knobby" type of T-cell leukemia, and T-prolymphocytic leukemia/T-cell lymphocytic leukemia. (wikipedia.org)
  • People affected by T-cell prolymphocytic leukemia typically have systemic disease at presentation, including enlargement of the liver and spleen, widespread enlargement of the lymph nodes, and skin infiltrates. (wikipedia.org)
  • T-cell prolymphocytic leukemia is difficult to treat, and it does not respond to most available chemotherapeutic drugs. (wikipedia.org)
  • Despite its overall rarity, it is also the most common type of mature T cell leukemia. (wikipedia.org)
  • These white blood cells are not fully developed and are called blasts or leukemia cells. (wikipedia.org)
  • Chronic leukemia is characterized by the excessive buildup of relatively mature, but still abnormal, white blood cells. (wikipedia.org)
  • mammals
  • In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. (wikipedia.org)
  • fate
  • The mechanisms determining the ultimate fate of neural stem cells are conserved among both invertebrate and vertebrate species and are determined from extracellular cues generated from neighboring cells. (wikipedia.org)
  • Based on the histone code hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell. (wikipedia.org)
  • cellular
  • Finally, microglial cells are derived from glial precursors and carry-out macrophage like properties to remove cellular and foreign debris within the central nervous system ref. (wikipedia.org)
  • regulate
  • Thus, elaborate intracellular-mechanisms based on environmental signals are present to regulate the formation of these cells. (wikipedia.org)