AnnulareSubcutaneousBenignLesionsFibrosisPyogenicEtiologyCutaneousPeripheral giant celLesionInguinaleKnown as granulomaTumorsGranulomatousRarelyAnnularSymptomsSystemicSarcoidosisInflammationUsually asymptomaticCondition characterizedNecrosisRelatively uncommonOccurNodulesHistologicallyInfectionDiseaseVasculitisDisorderLymphocytesExposureClinical featuresPlaquePrevalenceDistinctGiantDevelopPlaques
Annulare33
- Granuloma annulare (GA) is a common, sometimes chronic skin condition which presents as reddish bumps on the skin arranged in a circle or ring. (wikipedia.org)
- Aside from the visible rash, granuloma annulare is usually asymptomatic. (wikipedia.org)
- citation needed] Granuloma annulare microscopically consists of dermal epithelioid histiocytes around a central zone of mucin-a so-called palisaded granuloma. (wikipedia.org)
- Granuloma annulare is an idiopathic condition, though many catalysts have been proposed. (wikipedia.org)
- Most lesions of granuloma annulare disappear in pre-pubertal patients with no treatment within two years while older patients (50+) have rings for upwards of 20 years. (wikipedia.org)
- The disease was first described in 1895 by Thomas Colcott Fox as a "ringed eruption of the fingers", and it was named granuloma annulare by Henry Radcliffe Crocker in 1902. (wikipedia.org)
- Granuloma annulare (GA) is a long-term ( chronic ) skin disease consisting of a rash with reddish bumps arranged in a circle or ring. (medlineplus.gov)
- What is granuloma annulare? (hopkinsmedicine.org)
- Granuloma annulare is a benign skin condition characterized by small, raised bumps that form a ring with a normal or sunken center. (hopkinsmedicine.org)
- The cause of granuloma annulare is unknown and it is found in patients of all ages. (hopkinsmedicine.org)
- What are the symptoms of granuloma annulare? (hopkinsmedicine.org)
- The following are the most common signs or symptoms of granuloma annulare. (hopkinsmedicine.org)
- The symptoms of granuloma annulare may resemble other skin conditions. (hopkinsmedicine.org)
- How is granuloma annulare diagnosed? (hopkinsmedicine.org)
- Because granuloma annulare usually causes no symptoms and clears up by itself, you may not need treatment (except for cosmetic reasons). (hopkinsmedicine.org)
- Most granuloma annulare rashes resolve without treatment within 2 years. (hopkinsmedicine.org)
- There is debate around whether it is a distinct entity or a variant of granuloma annulare . (dermnetnz.org)
- Actinic granuloma is difficult to distinguish from other granulomatous disorders, particularly granuloma annulare and necrobiosis lipoidica . (dermnetnz.org)
- The spectrum of primary cutaneous elastolytic granulomas and their distinction from granuloma annulare: a clinic pathological analysis. (dermnetnz.org)
- The differential diagnosis of NL includes principally granuloma annulare and necrobiotic xanthogranuloma, both of which share clinical and histopathologic similarities with NL. (dermatologyadvisor.com)
- Granuloma annulare is noncancerous, noncontagious condition that causes ring-shaped patches on the skin. (zwivel.com)
- Granuloma annulare usually resolves on its own, but severe forms may require treatment. (zwivel.com)
- Found in patients of all ages, granuloma annulare is a common and benign skin condition that produces ring-shaped lesions, generally on the hands and feet. (zwivel.com)
- Although there is no known cure for granuloma annulare and it generally self-resolves, dermatologists may recommend various treatments to alleviate its symptoms. (zwivel.com)
- Granuloma annulare (GA), also known as necrobiotic papulosis, is a relatively common and noncontagious condition that produces smooth, thick patches on the skin. (zwivel.com)
- Young girls and young adults of both sexes are the most commonly affected, but since it arises from an immune response, anyone can develop granuloma annulare. (zwivel.com)
- Subcutaneous granuloma annulare is seen exclusively in children , causing rubbery lumps to develop on the skin. (zwivel.com)
- Interstitial granuloma annulare, also referred to as interstitial granulomatous dermatitis, describes more widespread plaques or papules covering significant areas of the trunk - especially on the back - that cause bouts of itching and burning sensations. (zwivel.com)
- Granuloma annulare is an uncommon benign inflammatory dermatosis characterized by the formation of dermal papules with a tendency to form rings. (elsevierpure.com)
- We report the radiologic appearance of five cases of subcutaneous granuloma annulare. (elsevierpure.com)
- The radiologic images of five patients (three male, two female) with subcutaneous granuloma annulare were retrospectively studied. (elsevierpure.com)
- The radiologic appearance of subcutaneous granuloma annulare is characteristic, typically demonstrating a nodular soft-tissue mass involving the subcutaneous adipose tissue. (elsevierpure.com)
- This radiologic appearance in a young individual is highly suggestive of subcutaneous granuloma annulare. (elsevierpure.com)
Subcutaneous2
- Complications of skin and soft tissues can be atrophy, fibrosis, numbness, cysts originating from displaced mucosa or subcutaneous granulomas caused by ointment material. (egms.de)
- Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
Benign6
- Pyogenic granulomas (PGs) are benign vascular lesions that occur most commonly on the acral skin of children. (medscape.com)
- Central giant cell granuloma, also called giant cell reparative granuloma, is an uncommon (7% of benign jaw lesions), cystic, intraosseous lesion of the anterior mandible and maxilla. (pathologyoutlines.com)
- BACKGROUND: Milia en plaque is a rarely described benign lesion characterized by milia within an erythematous base, usually located periauricularly. (lookfordiagnosis.com)
- A pyogenic granuloma is one of the most common benign tumors in the head and neck. (ejao.org)
- Granuloma faciale (GF) is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring over the face. (medscape.com)
- The Central giant cell granuloma (CGCG) is an uncommon idiopathic benign intraosseous lesion, most frequently found in young women, and most cases occur in the mandible. (bvsalud.org)
Lesions8
- This review highlights the physical appearance of and historical findings associated with these lesions, which can aid in diagnosing common and uncommon diseases ( Table 1 ) . (aafp.org)
- [ 11 , 12 , 13 ] Satellite lesions of smaller pyogenic granulomas may develop at the same time as the primary lesion or may occur after attempted treatment of the primary lesion. (medscape.com)
- Pyogenic granulomas are usually solitary lesions. (medscape.com)
- Mass lesions in the brain are uncommon ( 4 ). (cdc.gov)
- In sarcoidosis, small foci of fibrosis around granulomas can be an expected finding, and small areas of macroscopic fibrosis may occur at sites of healed inflammatory lesions. (livingwithsarcoidosis.org)
- Reports of granuloma faciale-like lesions of the oral mucosa are rare. (medscape.com)
- Roustan G, Sánchez Yus E, Salas C, Simón A. Granuloma faciale with extrafacial lesions. (medscape.com)
- Nasiri S, Rahimi H, Farnaghi A, Asadi-Kani Z. Granuloma faciale with disseminated extra facial lesions. (medscape.com)
Fibrosis3
- all are characterized by acute interstitial inflammation and development of granulomas and fibrosis with long-term exposure. (merckmanuals.com)
- The granulomas may resolve spontaneously or progress to fibrosis. (radiopaedia.org)
- Granuloma Faciale and Eosinophilic Angiocentric Fibrosis: Similar Entities in Different Anatomic Sites. (medscape.com)
Pyogenic16
- Recognition of pyogenic granuloma as a clinically polypoid or exophytic circumscribed lesion is of importance to the clinician and pathologist because this feature distinguishes pyogenic granulomas from most malignant vascular tumors. (medscape.com)
- Although pyogenic granulomas may be multiple (especially on the skin) and necrosis is common, invasion of adjacent structures is not observed. (medscape.com)
- Pyogenic granulomas usually bleed with little or no trauma. (medscape.com)
- Pyogenic granulomas usually have a distinct margin that consists of a rim of keratin (dry skin). (medscape.com)
- Pyogenic granulomas may be pedunculated and quite large. (medscape.com)
- Pyogenic granulomas may occur at various sites. (medscape.com)
- Small pyogenic granuloma. (medscape.com)
- Pyogenic granulomas (PGs) appear as smooth firm nodules, with or without crusts, and they may have a bright or dusky red color. (medscape.com)
- the presence of a vascular birthmark in the region of the pyogenic granuloma may be significant. (medscape.com)
- Amelanotic melanoma may closely mimic a pyogenic granuloma in appearance. (medscape.com)
- Pyogenic granulomas may develop, requiring removal of the plug. (aao.org)
- In most cases, the pyogenic granuloma regresses once the plug is removed, but surgical excision is needed on occasion. (aao.org)
- During the past few years there has been an increasing awareness of the condition wherein multiple satellite pyogenic granulomas develop after the primary lesion is treated or traumatized. (jamanetwork.com)
- We report a case of a pyogenic granuloma that involved the both EAC in a pregnant woman. (ejao.org)
- In a literature review, we found five case reports of pyogenic granulomas of the EAC dated up to December 2017 ( Table 1 ) [ 2 - 6 ]. (ejao.org)
- Both masses were round and firm, and were stalked on the anteroinferior walls of both EACs distant from the tympanic membranes ( Fig. 2C , D ). Histopathologically, the tumors were pyogenic granulomas ( Fig. 3 ). (ejao.org)
Etiology3
- The peripheral giant cell granuloma has an unknown etiology, with some dispute as to whether this lesion represents a reactive or neoplastic process. (medscape.com)
- Sarcoidosis is a multisystem disorder of unknown etiology characterized by the formation of inflammatory non-caseating granulomas within affected tissues. (radiopaedia.org)
- This is an uncommon disease of an unknown etiology with the prevalence of five cases per 100,000 in the European population and equal distribution among sexes [ 2 , 3 ]. (ejao.org)
Cutaneous2
- Case report: Persistent shedding of a live vaccine-derived rubella virus in a young man with severe combined immunodeficiency and cutaneous granuloma. (cdc.gov)
- A young man with X-linked severe combined immunodeficiency developed a persistent vaccine-derived rubella virus (VDRV) infection, with the emergence of cutaneous granulomas more than fifteen years after receipt of two doses of measles-mumps-rubella (MMR) vaccine. (cdc.gov)
Peripheral giant cel25
- However, most authorities believe peripheral giant cell granuloma is a reactive lesion. (medscape.com)
- This peripheral giant cell granuloma involved the maxillary gingiva associated with an erupting central incisor of a 6-year-old girl. (medscape.com)
- The cause of peripheral giant cell granuloma is unknown, although local irritation due to dental plaque or calculus, periodontal disease, poor dental restorations, ill-fitting dental appliances, or dental extractions has been suggested to contribute to the development of the lesion. (medscape.com)
- Reports have described the development of the peripheral giant cell granuloma in association with dental implants. (medscape.com)
- Peripheral giant cell granuloma is uncommon but not rare. (medscape.com)
- No known racial predilection is associated with peripheral giant cell granuloma. (medscape.com)
- One institutional biopsy service reported the mean age of 235 patients with peripheral giant cell granuloma to be 46 years, with a range from 6-88 years. (medscape.com)
- Peripheral giant cell granuloma has an excellent prognosis. (medscape.com)
- Peripheral giant cell granuloma: An updated analysis of 2824 cases reported in the literature. (medscape.com)
- Bischof M, Nedir R, Lombardi T. Peripheral giant cell granuloma associated with a dental implant. (medscape.com)
- Hirshberg A, Kozlovsky A, Schwartz-Arad D, Mardinger O, Kaplan I. Peripheral giant cell granuloma associated with dental implants. (medscape.com)
- An analysis of peripheral giant cell granuloma associated with dental implant treatment. (medscape.com)
- Etoz OA, Demirbas AE, Bulbul M, Akay E. The peripheral giant cell granuloma in edentulous patients: report of three unique cases. (medscape.com)
- Growth potential of peripheral giant cell granuloma. (medscape.com)
- Peripheral giant cell granuloma in anterior maxilla: case report in a child. (medscape.com)
- Histological evaluation of the possible transformation of peripheral giant cell granuloma and peripheral ossifying fibroma: A preliminary study. (medscape.com)
- Peripheral giant cell granuloma associated with hyperparathyroidism secondary to end-stage renal disease: a case report. (medscape.com)
- The differential diagnosis includes peripheral giant cell granuloma, giant cell tumor, aneurysmal bone cyst, brown tumor of hyperparathyroidism, giant cell-rich osteosarcoma, and metaphyseal fibrous defect / nonossifying fibroma. (pathologyoutlines.com)
- Dayan D, Buchner A, Spirer S. Bone formation in peripheral giant cell granuloma. (medscape.com)
- Sahingur SE, Cohen RE, Aguirre A. Esthetic management of peripheral giant cell granuloma. (medscape.com)
- Banthia R, Maheshwari S, Banthia P, Mantri K. Peripheral giant cell granuloma: a case report. (medscape.com)
- Grand E, Burgener E, Samson J, Lombardi T. Post-traumatic development of a peripheral giant cell granuloma in a child. (medscape.com)
- An aggressive peripheral giant cell granuloma in a child. (medscape.com)
- Peñarrocha-Diago MA, Cervera-Ballester J, Maestre-Ferrín L, Peñarrocha-Oltra D. Peripheral giant cell granuloma associated with dental implants: clinical case and literature review. (medscape.com)
- Biopsy helped confirm the diagnosis of peripheral giant cell granuloma. (medscape.com)
Lesion2
- A unifocal renal lesion is usually uncommon and can resemble a necrotic renal cell carcinoma [1]. (buyresearchchemicalss.net)
- A mucosal variant of the skin lesion granuloma faciale. (medscape.com)
Inguinale2
- K granulomatis infection can result in granuloma inguinale or donovanosis, although these are uncommon in developed temperate countries. (medscape.com)
- They include morbidity data, incidence rates by county, and the following STIs: Chlamydia, Gonorrhea, Syphilis, Herpes simplex-initial genital infection & Uncommon STIs - including chancroid, lymphogranuloma venereum (LGV) and granuloma inguinale (GI). (wa.gov)
Known as granuloma2
- Besides inflamed blood vessels, it produces a type of inflammatory response known as granuloma, which can destroy normal tissue. (arthritis-unplugged.com)
- Henderson suffers from sarcoidosis, a uncommon inflammatory illness that causes the organs to change into lined in lumpy nodes known as granuloma. (metechyou.com)
Tumors1
- Differential diagnoses in radiologic studies include local abscess, granuloma, xanthogranulomatous pyelonephritis, lymphoma and multifocal primary or metastatic tumors [8]. (buyresearchchemicalss.net)
Granulomatous3
- The term granulomatous hepatitis is often used to describe the condition, but the disorder is not true hepatitis, and the presence of granulomas does not imply hepatocellular inflammation. (msdmanuals.com)
- Idiopathic granulomatous hepatitis is a rare syndrome of hepatic granulomas with recurrent fever, myalgias, fatigue, and other systemic symptoms, which often occur intermittently for years. (msdmanuals.com)
- [ 1 ] The granulomas of tuberculosis (see the first image below) are necrotizing and non-necrotizing, with involvement of lung parenchyma leading to peribronchial, perivascular, interstitial and alveolar granulomas and occasionally leading to exudative tuberculous granulomatous pneumonia (see the second image below). (medscape.com)
Rarely3
- Hepatic granulomas rarely affect hepatocellular function. (msdmanuals.com)
- M marinum infection, often called swimming pool granuloma, is rarely associated with exposure to swimming pools because of advances in chlorination. (contemporarypediatrics.com)
- Although temporal bone involvement is not uncommon, an otologic disorder is rarely the initial symptom. (ejao.org)
Annular2
- Actinic granuloma is an uncommon skin disease that presents with asymptomatic annular (ring-shaped) plaques on sun-exposed sites. (dermnetnz.org)
- Actinic granuloma begins as flesh-coloured or pink papules (small bumps) which coalescence into annular plaques (larger thickened patches) ranging in size from 1 to 10 cm in diameter. (dermnetnz.org)
Symptoms3
- Considering the high prevalence of GERD, reflux laryngitis and its symptoms are uncommon. (medicinenet.com)
- Although uncommon, systemic GPA may cause initial otologic symptoms and should not be dismissed as a possible cause of an otologic disease resistant to standard therapy. (ejao.org)
- Hypersensitivity pneumonitis, also known as extrinsic allergic alveolitis, is an uncommon non-immunoglobulin E (IgE), T-helper cell type 1 (Th1)-mediated inflam- matory pulmonary disease with systemic symptoms resulting from repeated inhalation and subsequent sensitization to a large variety of aerosolized antigenic organic dust particles. (cdc.gov)
Systemic2
- No systemic involvement has been reported with granuloma faciale. (medscape.com)
- Sarcoidosis is a systemic disease caused by noncaseating granulomas in multiple organs. (medscape.com)
Sarcoidosis1
- Renal involvement is an uncommon feature of sarcoidosis and it is essential to establish a fast and correct diagnosis because early therapy avoids progression to terminal renal failure. (medscape.com)
Inflammation1
- Granulomas and nonspecific inflammation are characteristic of M marinum infection. (contemporarypediatrics.com)
Usually asymptomatic1
- Hepatic granulomas have numerous causes and are usually asymptomatic. (msdmanuals.com)
Condition characterized1
Necrosis2
- In conjunction with tumor necrosis factor (TNF)-α signaling, these cell-mediated responses result in the formation of granulomas, the histopathologic hallmark of disease. (livingwithsarcoidosis.org)
- The ingredients may otherwise cause local tissue necrosis and granuloma in the lungs. (who.int)
Relatively uncommon2
- These infectious presentations are relatively uncommon. (medscape.com)
- Tetracyclines, trimethoprim/sulfamethoxazole, macrolides, quinolones, rifampin, and ethambutol are effective options-although there have been no controlled studies on optimal treatment because the infection is relatively uncommon. (contemporarypediatrics.com)
Occur2
- Small granulomas occasionally occur in other liver disorders but are not clinically significant. (msdmanuals.com)
- granulomas may occur in the hepatic triads. (msdmanuals.com)
Nodules1
- Small nodules or granulomas may form in response to the filler material. (whiteclinic.com.sg)
Histologically1
- Histologically, central giant cell granulomas are characterized by spindle cells within fibrous stroma, with numerous multinucleated giant cells in a patchy distribution, usually near areas of hemorrhage. (pathologyoutlines.com)
Infection3
- Intracerebral granuloma associated with brucellosis had been reported in a community-acquired infection ( 6 ). (cdc.gov)
- Granuloma - Focal collection of inflammatory cells at sites of tissue infection and includes activated macrophages (epithelioid cells), Langhans' giant cells, and lymphocytes. (medscape.com)
- It is uncommon in Greece and the Western World, but high rates of HIV infection have been reported in patients with soft ulcer in the United States and other countries. (andromedlabs.gr)
Disease3
- Magnetic resonance imaging of the brain of a 46-year-old immunocompromised woman with central nervous system brucellosis granuloma and white matter disease, Saudi Arabia. (cdc.gov)
- Hepatic granulomas, although sometimes insignificant, more often reflect clinically relevant disease. (msdmanuals.com)
- Granuloma faciale is primarily a disease of middle age (median age, 45 y). (medscape.com)
Vasculitis1
- Vassallo C, Derlino F, Croci GA, Brazzelli V, Borroni G. Chronic localized leukocytoclastic vasculitis: clinicopathological spectrum of granuloma faciale with and without extrafacial and mucosal involvement. (medscape.com)
Disorder1
- Churg-Strauss syndrome is an uncommon disorder, and it affects males and females equally. (arthritis-unplugged.com)
Lymphocytes1
- The exaggerated immune response to repeated inhalation of these particles leads to infiltration and proliferation of activated pulmonary macrophages and lymphocytes, resulting in lymphocytic alveolitis and bronchiolitis with noncaseating granulomas. (cdc.gov)
Exposure1
- It is now more commonly acquired through exposure to aquariums (fish tank granuloma) and other water recreation activities. (contemporarypediatrics.com)
Clinical features1
- What are the clinical features of actinic granuloma? (dermnetnz.org)
Plaque2
- OBJECTIVE: To illustrate by a case report the clinical presentation and effect of dermabrasion on milia en plaque. (lookfordiagnosis.com)
- Solitary, well-demarcated, brown-red plaque associated with granuloma faciale. (medscape.com)
Prevalence1
Distinct1
- Lever and Leeper first recognized granuloma faciale as a distinct entity in 1950. (medscape.com)
Giant4
- Some investigators have suggested that peripheral giant cell granulomas that develop in association with dental implants seem to have a higher risk for recurrence. (medscape.com)
- Lester SR, Cordell KG, Rosebush MS, Palaiologou AA, Maney P. Peripheral giant cell granulomas: a series of 279 cases. (medscape.com)
- A granuloma is a localized collection of chronic inflammatory cells with epithelioid cells and giant multinucleated cells. (msdmanuals.com)
- Giant Cell Granuloma. (bvsalud.org)
Develop1
- Granulomas may develop in response to poorly soluble exogenous or endogenous irritants. (msdmanuals.com)
Plaques1
- Multiple brown-red plaques on the face associated with granuloma faciale (same patient as in Media Files 13-16). (medscape.com)