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  • ESCs
  • Therefore, Oct-4A, despite its essential roles in ESCs, neither defined nor conferred self-renewal of CD133+ cells. (tdl.org)
  • r\nTo discover strategies to grow immature CD133+ cells without differentiation, we focused on the Wnt pathway which is essential for self-renewal in ESCs. (tdl.org)
  • immature
  • Towards this goal, our lab adapted a culture technique to grow immature CD133+ UCBSCs (CD133+ cells). (tdl.org)
  • HSCT
  • A second HSCT was planned with cord blood as the graft source, because disease progression implied a need for an urgent care. (hindawi.com)
  • A third HSCT using cord blood as the graft source was planned in non-CR status after treatment with a hypomethylating agent, azacitidine, [ 1 , 2 ] at the age of 53 again, because the patient had no significant comorbidities. (hindawi.com)
  • neural
  • Thus, after exposure to different agents, these cells are able to express antigens of diverse cellular lineages, including the neural type [ 26 - 31 ]. (hindawi.com)
  • A new study of mitochondrial deficits in iPSC-derived neural cells, funded by the National Institutes of Health and published in Science Translational Medicine, shows that patient-derived stem cells yield differing responses for cells derived from patients with different etiologies of Parkinson's disease. (stemcellumbilicalcordblood.com)
  • differentiate
  • These cells are defined by their ability to self-renew as well as to differentiate into committed progenitors of the different myeloid and lymphoid compartments generating all of the blood cell lineages (1). (scielo.br)
  • Induced pluripotent stem cells are the third category, where somatic cells are induced to convert into pluripotent stem cells under certain condition and differentiate into a specific cell types [ 2 , 3 ]. (omicsonline.org)
  • GVHD
  • Unfortunately, the donor stem cells may also attack a patient's healthy tissues, a condition referred to as graft-versus-host-disease (GVHD). (cancerconnect.com)
  • Due to the potential severity of GVHD, researchers try to use stem cell donors who are either related to the patient and/or have specific proteins of the stem cell called HLA proteins that are matched as closely as possible. (cancerconnect.com)
  • expansion
  • We determined if the altered expression of adhesion molecules during stem cell expansion could be a reason for the discrepancy. (scielo.br)
  • In Kolkata, a top official said that one of the leading stem cell banking groups in the Asia Pacific region, CordLife, is targeting an expansion of its business into China and India. (stemcellumbilicalcordblood.com)