Ultraviolet abnormalities radiation induced. Medical search. Frequent questions

At the conclusion of the long-term study, they found that there was no significant increase in chromosomal abnormalities during the solar eclipse. (securefamily.in)
[6] Numerical chromosomal abnormalities associated with OS include loss of chromosomes 9, 10, 13, and 17 as well as gain of chromosome. (ijofb.org)
These ROS react with cellular macromolecules including DNA, RNA, membrane lipids, and proteins, leading to cellular dysfunction and DNA damage, resulting in chromosomal abnormalities and mutations that cause cancers. (e-algae.org)

Overexposure to UV in normal skin will induce p53-dependent apoptosis, which may serve to protect the skin from damaged cells. (medscape.com)
Basal keratinocytes with mutated TP53 may not respond normally to UV-induced apoptosis, allowing further proliferation and development of new genetic abnormalities. (medscape.com)
These mechanisms may either repair the DNA damage or induce apoptosis of these cells. (ijofb.org)
If the damage is extensive, it can induce APOPTOSIS. (lookformedical.com)

It is potentially lethal and mutagenic and can induce chemical alterations in body tissues, which could result in a series of harmful effects. (e-algae.org)

Other mechanisms have been proposed to explain the role of ultraviolet or visible light radiation in drug-induced pseudoporphyria. (medscape.com)
Familial AN, drug-induced AN, AN occurring in hyperinsulinemic states (eg, diabetes, obesity), AN associated with polycystic ovary disease, and AN associated with a spectrum of autoimmune disease in women should be considered before AN is determined to represent a paraneoplastic syndrome. (medscape.com)
Diagnostic criteria for sweet syndrome, including classical, drug-induced and malignancy-associated forms. (actasdermo.org)

Chronic exposure to ultraviolet light (UV) or sunlight is one of the most important factors in the development of actinic keratoses. (medscape.com)
These individual apoptotic keratinocytes are often referred to as "sunburn" cells and are seen histologically in the epidermis of skin overexposed to sunlight or UV radiation. (medscape.com)
DNA can be damaged by ultraviolet (UV) rays from sunlight and by toxic chemicals, such as those found in cigarette smoke. (medlineplus.gov)
Ultraviolet radiation from sunlight causes painful and temporary conditions like sunburn and "sun poisoning," as well as more ominous long-term effects such as skin aging and skin cancer. (lifeextension.com)
Factors like ultraviolet radiation of sunlight and toxic chemical can affect your melanocyte cells' function. (reviewsfellas.com)

Among these, the role of ultraviolet and ionizing radiation is the best established. (ijofb.org)

This orally ingested natural fern extract has a high affinity for the skin where it has been shown to protect against ultraviolet damage that can cause premature aging and skin cancer. (lifeextension.com)
Maca has been used to treat nutritional deficiencies, support healthy energy levels, enhance fertility in both males and females, improve memory, protect against ultraviolet radiation, and promote balanced hormones. (takecareof.com)

Supported by extensive research, this new oral supplement offers convenient protection against ultraviolet light damage to the largest organ of the body… our skin! (lifeextension.com)
Moreover, radioprotective substances are used as ingredients in cosmetic formulations in order to provide protection against ultraviolet radiation. (e-algae.org)

The aim of their research was to assess radiation-induced cytogenetic toxicity in bone marrow cells during a solar eclipse. (securefamily.in)
Radioprotective natural products have particularly received attention for their potential usefulness in counteracting radiation-induced damage because of their reduced toxicity compared with most drugs currently in use. (e-algae.org)
Sujet : Évaluation de la pharmacocinétique, de la pharmacodynamique et de la toxicity du robénacoxib chez la truite arc-en-ciel ( Oncorhynchus mykiss ). (umontreal.ca)

In January 2009, Vibudh Prakash Kesari of Ram Jaipal College, Chapra (Bihar), Parimal Kumar Khan of Patna University and SK Srivastava tried to see the effect of radiation on mouse chromosomes during a solar eclipse. (securefamily.in)
Aneuploidy is an abnormality in the number of chromosomes in a cell due to loss or duplication. (genome.gov)

Obtain a baseline electrocardiogram (ECG) to determine whether preexisting conduction abnormalities are present. (drugs.com)

Studies suggest that the neurological abnormalities associated with this condition result from a buildup of DNA damage, although the brain is not exposed to UV rays. (medlineplus.gov)
Modern dermatological researchers have discovered that the oral ingestion of this fern may provide previously unavailable skin cancer protection by blocking dangerous ultraviolet (UV) rays in living skin. (lifeextension.com)
Ionizing radiation includes electromagnetic radiation such as far ultraviolet light, X-rays, gamma rays, ionizing subatomic particles such as α and β particles, and high energy neutrons and positrons resulting from radioactive decay and cosmic ray showers ( Woodside and Kocurek 1997 ). (e-algae.org)
Investigations on strategies for protecting human tissues from ionizing radiation were initiated during the early nineteenth century after the discovery of X-rays. (e-algae.org)
They are also highly resistant to ultraviolet rays and radiation methods normally used to achieve sterilization. (factdr.com)
Exposure to UV radiation, particularly UVA rays (long wave Ultraviolet radiation ) causes changes in our melanocyte ( pigment cellular) genes. (doctorhoogstra.com)

UV-induced mutations of the tumor suppressor gene TP53 are of major importance in the development of actinic keratosis. (medscape.com)
Basal cell carcinomas, the commonest human skin cancers, consistently have abnormalities of the hedgehog signaling pathway and often have PTCH gene mutations. (nature.com)

citation needed] Additionally, the vast majority of non-invasive cancers are non-melanoma skin cancers caused by ultraviolet radiation (which lies on the boundary between ionizing and non-ionizing radiation). (wikipedia.org)
5 Aging people are much more vulnerable to contracting skin cancers from even limited exposure to solar radiation. (lifeextension.com)
Oral Polypodium leucotomos supplements may afford long-term protection from ultraviolet light-related skin aging and even from cellular changes that can lead to skin cancers. (lifeextension.com)

An elevated arterial or free venous serum ammonia level is the classic laboratory abnormality reported in patients with hepatic encephalopathy. (medscape.com)

Our results also suggest that environmental insults, such as heat stress, could contribute to an aberrant E2F1 activity by inducing E2F1 mRNA expression. (biomedcentral.com)

In addition to sun sensitivity, xeroderma pigmentosum is sometimes associated with progressive neurological abnormalities. (medlineplus.gov)
In affected individuals with the Phe99Ser variant, neurological abnormalities have been relatively mild and have included hearing loss and poor coordination. (medlineplus.gov)
However, significant neurological symptoms accompanied by detectable abnormalities in the central nervous system may only manifest when the disease has attained a more advanced stage. (factdr.com)

In addition to conventional fatalities and acute radiation syndrome fatalities, nine children died of thyroid cancer, and it is estimated that there may be up to 4,000 excess cancer deaths among the approximately 600,000 most highly exposed people. (wikipedia.org)
Methotrexate-induced lung disease, including acute or chronic interstitial pneumonitis, is a potentially dangerous lesion, which may occur acutely at any time during therapy and has been reported at low doses. (nih.gov)
1 We have shown previously that acute exposure to 2 ppm NO 2 can induce an acute inflammatory response in healthy human airways. (bmj.com)
5, 6 We have also shown that repeated daily exposure to NO 2 (2 ppm for four hours/day for four successive days) can induce a decrement in FEV 1 that returns to baseline by day 4, but the acute inflammatory response characterised by PMN influx and activation still persists after the final exposure. (bmj.com)

Postoperative radiation can also be a useful adjunct when patients have aggressive tumors that were treated surgically or when surgery has failed to clear the margins of the tumor. (medscape.com)
Like other cytotoxic drugs, methotrexate may induce "tumor lysis syndrome" in patients with rapidly growing tumors. (nih.gov)
Tumor-induced osteomalacia has similar clinical manifestations to the familial syndromes. (boneandspine.com)

Although pseudoporphyria has no predilection toward any one race, it has been shown that fair-skinned children who are highly prone to sunburn are more likely to develop naproxen-induced pseudoporphyria than those children with skin types III or higher. (medscape.com)
Oral Polypodium leucotomos supplements, taken in doses of 500-750 mg/day, have been shown to protect human skin from sunburn, cell death, DNA damage, and oxidant activity from both natural and artificial ultraviolet light. (lifeextension.com)

[ 2 ] Factors leading to an increased incidence of actinic keratosis include cumulative ultraviolet radiation exposure, increasing age, childhood sun exposure, male sex, and residing in latitudes close to the equator. (medscape.com)
The problem is intrinsic factors, such as the biological aging process, as well as extrinsic factors, such as ultraviolet radiation from sun exposure, compromise the structure and function of these proteins. (lifeextension.com)

Exposure to ionizing radiation is known to increase the future incidence of cancer, particularly leukemia. (wikipedia.org)
Higher incidence of these abnormalities or lesions are found in fair-skinned people in countries with a sunny climate or closer to the equator, and with people with outdoor occupations and those who enjoy outdoor activities. (herbs.org.nz)

Objectives: Primary Objectives: To induce cellular and humoral immunity in allogeneic stem cell donors and recipients against the unique idiotype expressed by the recipient's myeloma. (drugpatentwatch.com)

Actinic keratosis is an erythematous scaly papule or plaque that develops on sun-damaged skin as a result of chronic exposure to ultraviolet radiation, typically in elderly patients with lighter skin types. (medscape.com)
Areas of skin that are heavily exposed to ultraviolet (UV) light are the most common locations for actinic keratoses. (medscape.com)
Our skin is exposed to majority of UV radiation during outdoor activities, e.g. walking, practicing sports, running, hiking, etc. and not when we are intentionally exposed to the sun on the beach. (researchgate.net)
UV-induced photoaging of the skin becomes clinically evident with age, when endogenous antioxidative mechanisms and repair processes are not effective any more and actinic damage to the skin prevails. (researchgate.net)
While some sun exposure can be beneficial for generating vitamin D and improved moods, an excess of ultraviolet exposure can seriously harm our skin," Dr Noaf Saif Al Mahmood, dermatology specialist at SEHA's Ambulatory Healthcare Services, told Khaleej Times. (menafn.com)
Additionally, Dr Noaf recommended a yearly skin check-up by a certified professional to address any skin abnormalities. (menafn.com)
Blood tests and immunofluorescence testing of skin and serum are also utilized to validate abnormalities within the body. (imarcgroup.com)
Furthermore, the rising prevalence of exposure to ultraviolet light and ionizing radiation, resulting in premature aging and damage to the skin, is also propelling the market growth. (imarcgroup.com)
Scientists have discovered an orally ingested nutrient that protects the skin against DNA damage from harmful solar radiation. (lifeextension.com)
Ultraviolet radiation directly damages DNA and impairs normal skin cell functions by generating enormous bursts of free-radical activity. (lifeextension.com)
The aim of the study was to evaluate the efficacy of 2% Cynara scolymus L. extracts in reverse disturbances of collagen metabolism and inflammation in D-galactose induced skin aging model in rats. (scirp.org)
Local prolonged treatment with artichoke extracts improved collagen metabolism and attenuated the progression of inflammation in D-galactose induced skin aging model. (scirp.org)
Photosensitivity (with easy skin blistering after modest sun exposure), early freckling, and the development of lentiginous pigmentation are all symptoms of poor UV-radiation-induced damage healing. (news-medical.net)
The disease pathogenesis was identified as congenital excessive sensitization of the skin to ultraviolet radiation of the sun as early as 1926, with clear value in sun exposure prevention methods. (news-medical.net)
Patients with XP frequently exhibit unique clinical manifestations such as increased sensitivity to UV exposure (resulting in painful sunburns), skin dryness (also known as xerosis), and developing freckle-like pigmentary abnormalities. (news-medical.net)
Long-term sun exposure (particularly to UV light) has been shown to be the cause of sun-induced skin damage. (herbs.org.nz)
Generally, the more long-term sun exposure a person has the more likely they are to develop some type of sun-induced skin lesion, especially if the skin gets sunburnt. (herbs.org.nz)
As people age their skin has a tendency to develop 'abnormalities' which include areas of thickened, scaly skin. (herbs.org.nz)
The medical treatments available to treat sun-induced skin damage include destruction of the lesions with cryogens (freezing), electrodessication (burning), curettage (cutting), chemical peeling agents and medical therapy with chemicals such as 5-Flurouracil and retinoids. (herbs.org.nz)
These actions assist to counter the UVR (Ultra Violet Radiation) damage on human skin. (herbs.org.nz)
The main source (about 95%) is vitamin D3 (cholecalciferol) that is photochemically synthesized in the skin by ultraviolet-B radiation. (vitamindwiki.com)
UV radiation not only hurts your skin but also aggravates open pores. (missinglinkrecords.com)
Finally, excessive exposure to ultraviolet (UV) radiation from the sun or artificial sources, such as tanning beds, is a known cause of skin cancer, including melanoma, the most dangerous form of skin cancer. (the-socioesthetician-international.com)

Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice. (jci.org)
A new mouse cardiac electrophysiology method was used to study mice harboring an alpha-myosin heavy chain Arg403Gln missense mutation (alpha-MHC403/+), which results in histological and hemodynamic abnormalities characteristic of familial hypertrophic cardiomyopathy (FHC) and sudden death of uncertain etiology during exercise. (jci.org)

This study will investigate the safety and effectiveness of the drug Leflunomide to treat uveitis-an inflammation of the eye caused by an immune system abnormality. (drugpatentwatch.com)

The Sun and the main sources of solar radiation on Earth - infrared and ultraviolet radiation - are continuously being researched around the world. (securefamily.in)
Organisms are constantly exposed to ionizing radiation because radioactive materials are dispersed throughout the Earth, which is constantly bombarded by solar radiation and cosmic ray showers. (e-algae.org)

3] Pseudoporphyria has been reported in patients with chronic renal failure treated with hemodialysis and in those with excessive exposure to ultraviolet A (UV-A) by tanning beds. (medscape.com)

UV radiation can disrupt genes that control cell development and division, causing cells to die or grow too quickly and uncontrollably. (news-medical.net)

Hypophosphatemic rickets is a form of rickets that is characterized by low serum phosphate levels and resistance to treatment with ultraviolet radiation or vitamin D ingestion. (medscape.com)
Since the early 20th century, ultraviolet radiation or vitamin D ingestion has been recognized as a cure for nutritional rickets, although certain forms of rachitic disease have remained refractory to this therapy. (medscape.com)

This variant probably makes the TFIIH complex unstable and reduces its ability to repair DNA damage caused by UV radiation. (medlineplus.gov)
Cyclobutane pyrimidine dimers (CPDs) are the most common form of DNA damage induced by UV-B, and can be repaired through the production of photolyases that reversibly bind and convert CPDs back to the original bases. (dissertation.com)
Fight free radical damage: The more UV radiation you are exposed to, the more free radicals your body produces. (menafn.com)
Ultraviolet (UV) radiation, which causes free radical damage and increases the activity of enzymes that break down collagen and elastin. (lifeextension.com)
UV radiation from the sun, as well as hazardous compounds contained in cigarette smoke, can cause DNA damage. (news-medical.net)

Therefore, radiation during this period cannot be considered harmful to health. (securefamily.in)

Ionizing radiation is an electromagnetic wave or a high-energy particle that can penetrate matter, producing ions following its collapse while traveling in its path ( Varanda and Tavares 1998 ). (e-algae.org)

This study examined the penetration depth of ultraviolet (UV) light in the corneal limbus and assessed the safety of 222nm Far-UVC on stem cells in the basal area of the corneal limbus. (uvxinc.com)
Rats were exposed to various peaks of ultraviolet light. (uvxinc.com)

1992. Radiation dose assessment from ingestion pathway in Saudi Arabia. (cdc.gov)

Typical contributors to such risk include natural background radiation, medical procedures, occupational exposures, nuclear accidents, and many others. (wikipedia.org)
In accordance with ICRP recommendations, most regulators permit nuclear energy workers to receive up to 20 times more radiation dose than is permitted for the general public. (wikipedia.org)
Some occupations are exposed to radiation without being classed as nuclear energy workers. (wikipedia.org)
The use of ionizing radiation and radioactive elements is becoming increasingly popular with the rapid developments in nuclear technology, radiotherapy, and radio diagnostic methods. (e-algae.org)

Radon is responsible for the worldwide majority of the mean public exposure to ionizing radiation. (wikipedia.org)
Exposure to ionizing radiation triggers the production of reactive oxygen species (ROS) that mainly include hydroxyl, superoxide radicals, hydrogen peroxide and singlet oxygen ( Ewing and Jones 1987 ). (e-algae.org)

Alcohol consumption has been shown to induce anginal attacks in a large proportion of patients with variant angina with a lag time of 1.5 to 18 hours and to decrease exercise tolerance in patients with stable exertional angina. (deansilvermd.com)
Alcohol-induced variant angina may also be aggravated by magnesium deficiency, which is common in heavy alcohol users. (deansilvermd.com)

Epidemiological evidence shows a clear link between lung cancer and high concentrations of radon, with 21,000 radon-induced U.S. lung cancer deaths per year-second only to cigarette smoking-according to the United States Environmental Protection Agency. (wikipedia.org)

This means that for some people maca root can help stress levels, while for others it can work to rebalance their PMS-induced fatigue. (takecareof.com)
Stress may induce hormonal abnormalities, which promote excessive oil production and, consequently, pore enlargement. (missinglinkrecords.com)

Enthesopathy and dental abnormalities are mediated by mechanisms other than FGF23. (boneandspine.com)

[ 4 , 5 ] UV radiation acts as an initiator and promoter of carcinogenesis in actinic keratosis and squamous cell carcinoma. (medscape.com)

6] Animals injected with nalidixic acid and then exposed to ultraviolet radiation for 10 weeks exhibited more severe cutaneous manifestations than mice treated with sodium chloride solution. (medscape.com)

D-galactose induced aging reproduced in 48 animals of main group, and 12 rats in control group. (scirp.org)

radiation therapy (RT) can be used in patients with advanced and extended lesions, as well as in those for whom surgery is not suitable. (medscape.com)

Airline crews receive occupational exposures from cosmic radiation because of reduced atmospheric shielding at altitude. (wikipedia.org)

It also regulates body temperature through moisture control and reduces the harmful effects of UV radiation. (the-socioesthetician-international.com)

The development of radioprotective substances has attracted an increasing interest because of their potential use in radiotherapy, counteracting occupational radiation hazards, space exploration, and in research. (e-algae.org)

Stratospheric ozone depletion (the ozone hole) over the Antarctic, and the resulting increase of ultraviolet-B radiation (UV-B, 280 to 320 nm), poses a major threat to Antarctic marine ecosystems (Wulff, 2008). (dissertation.com)
I observed an increase in photolyase expression and abnormality with increased exposure to UV-B (either by ozone depletion or open water). (dissertation.com)
Environmental contamination with radioactive elements and the depletion of ozone layer also contribute to the increased levels of radiation exposure. (e-algae.org)

This estimate is criticized by the American College of Radiology (ACR), which maintains that the life expectancy of CT scanned patients is not that of the general population and that the model of calculating cancer is based on total-body radiation exposure and thus faulty. (wikipedia.org)

We report here that Ptch +/- mice develop primordial follicular neoplasms resembling human trichoblastomas, and that exposure to ultraviolet radiation or ionizing radiation results in an increase in the number and size of these tumors and a shift in their histologic features so that they more closely resemble human basal cell carcinoma. (nature.com)
However, ionizing radiation also has beneficial characteristics that could be helpful in treating human diseases. (e-algae.org)

Some drugs may act as photosensitizers, increasing susceptibility to UV radiation, whereas others may increase the risk for squamous cell carcinoma regardless of exposure to UV radiation. (medscape.com)
According to the prevalent model, any radiation exposure can increase the risk of cancer. (wikipedia.org)

It is often the single largest contributor to an individual's background radiation dose, and is the most variable from location to location. (wikipedia.org)
In industrialized countries, Medical imaging contributes almost as much radiation dose to the public as natural background radiation. (wikipedia.org)

if correct, natural background radiation is the most hazardous source of radiation to general public health, followed by medical imaging as a close second. (wikipedia.org)

Anatomy15

Organisms9

Diseases46

Chemicals and Drugs34

Analytical, Diagnostic and Therapeutic Techniques and Equipment76

Phenomena and Processes61

Disciplines and Occupations9

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture7

Humanities1

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Named Groups1

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Geographicals1

Chromosomal abnormalities3

Apoptosis4

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Sunlight5

Role of ultraviolet1

Protect against ultraviolet2

Protection against ultraviolet2

Toxicity3

Chromosomes2

Conduction1

Rays6

Mutations2

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Hepatic1

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Sunburn2

Factors2

Incidence2

Cellular1

Skin23

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Damage5

Considered harmful1

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Actinic1

Manifestations1

Rats1

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Harmful effects1

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Hazardous1