Ubiquitin-Protein LigasesLigasesUbiquitinUbiquitinsAngelman SyndromeUbiquitin-Conjugating EnzymesUbiquitin-Protein Ligase ComplexesUbiquitinationEndosomal Sorting Complexes Required for TransportProteasome Endopeptidase ComplexCullin ProteinsAnaphase-Promoting Complex-CyclosomeSKP Cullin F-Box Protein LigasesCarbon-Nitrogen LigasesMolecular Sequence DataAmino Acid SequenceProtein BindingF-Box ProteinsPolyubiquitinMutationUbiquitin-Activating EnzymesFatty Acid Synthase, Type IIS-Phase Kinase-Associated ProteinsBiotinylationRNA Ligase (ATP)Substrate SpecificityUbiquitin ThiolesteraseSaccharomyces cerevisiae Proteinsbeta-Transducin Repeat-Containing ProteinsBiotinCell Cycle ProteinsProtein Structure, TertiaryCell LineSequence Homology, Amino AcidF-Box MotifsPeptide SynthasesSaccharomyces cerevisiaeProteolysisThioctic AcidCarrier ProteinsCysteine EndopeptidasesMultienzyme ComplexesProtein Processing, Post-TranslationalAcetyl-CoA CarboxylaseDNA LigasesHeLa CellsHydroxyapatitesBase SequenceRepressor ProteinsRecombinant Fusion ProteinsMultiprotein ComplexesVon Hippel-Lindau Tumor Suppressor ProteinInhibitor of Apoptosis ProteinsAdenovirus E4 ProteinsProteinsTranscription FactorsHEK293 CellsRING Finger DomainsTwo-Hybrid System TechniquesPolynucleotide LigasesProtein StabilityModels, MolecularAmino Acid MotifsDNA-Binding ProteinsImmunoprecipitationRecombinant ProteinsUbiquitin CNuclear ProteinsEscherichia coliSignal Transductionvif Gene Products, Human Immunodeficiency VirusBacterial ProteinsRNA InterferenceProto-Oncogene Proteins c-cblGlutamate-Cysteine LigaseModels, BiologicalAdaptor Proteins, Signal TransducingEscherichia coli ProteinsRNA, Small InterferingPseudohypoaldosteronismCyclin-Dependent Kinase Inhibitor ProteinsTumor Suppressor ProteinsIntracellular Signaling Peptides and ProteinsSuppressor of Cytokine Signaling ProteinsProtein TransportCell Line, TumorAnkyrin RepeatCloning, MolecularElectrophoresis, Polyacrylamide GelAdenovirus E1B ProteinsPeptide HydrolasesLysineCell CyclePhosphorylationUbiquitinated ProteinsImmunoblottingBinding SitesTransfectionSUMO-1 ProteinLigase Chain Reaction