Tyrosine kinase inhibitor target proteins inhibitor protein. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Cell Line Cells, Cultured Tumor Cells, Cultured 3T3 Cells Mitochondria, Heart Cell Nucleus Submitochondrial Particles HeLa Cells COS Cells Fibroblasts Cytosol K562 Cells Cell Membrane Cell Line, Transformed

Organisms8

Cattle Mice, Nude Rats, Sprague-Dawley Mice, Knockout Mice, Inbred C57BL Eleusine Rabbits Escherichia coli

Diseases7

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lung Neoplasms Carcinoma, Non-Small-Cell Lung Gastrointestinal Stromal Tumors Angioedema Neoplasms Cell Transformation, Neoplastic

Chemicals and Drugs157

Small Molecule Libraries Protein Inhibitors of Activated STAT Protein Kinase Inhibitors Tyrosine Protein-Tyrosine Kinases Enzyme Inhibitors Pyrimidines Genistein Benzamides Quinazolines Phosphatidylethanolamine Binding Protein Receptor, Epidermal Growth Factor Piperazines Receptor Protein-Tyrosine Kinases src-Family Kinases Phosphatidylinositol 3-Kinases Tyrphostins Protein Kinases Antineoplastic Agents Protein-Serine-Threonine Kinases Indoles Proteins Pyrroles Proto-Oncogene Proteins Phosphotyrosine Protein Kinase C 5-Lipoxygenase-Activating Protein Inhibitors Intracellular Signaling Peptides and Proteins Protein Tyrosine Phosphatases Calcium-Calmodulin-Dependent Protein Kinases Lactams, Macrocyclic Fusion Proteins, bcr-abl Quinones Benzoquinones Carrier Proteins Proto-Oncogene Proteins c-abl Isoflavones Phosphoproteins Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 1 Recombinant Proteins Thiazoles Cyclin-Dependent Kinase Inhibitor p27 Pyridines fms-Like Tyrosine Kinase 3 Recombinant Fusion Proteins Proto-Oncogene Proteins c-kit Cyclic AMP-Dependent Protein Kinases SUMO-1 Protein Small Ubiquitin-Related Modifier Proteins RNA, Messenger Mitogen-Activated Protein Kinase 3 Cyclin-Dependent Kinases p38 Mitogen-Activated Protein Kinases Quinolines Proto-Oncogene Proteins pp60(c-src)Phenylurea Compounds Calcium Staurosporine Vanadates Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Cyclin-Dependent Kinase Inhibitor p21 Mitogen-Activated Protein Kinase Kinases Proto-Oncogene Proteins c-akt Tyrosine 3-Monooxygenase Epidermal Growth Factor Nitriles Phosphoprotein Phosphatases DNA-Binding Proteins Isoenzymes Proto-Oncogene Proteins c-fyn Adenosine Triphosphate JNK Mitogen-Activated Protein Kinases Receptors, Vascular Endothelial Growth Factor Focal Adhesion Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Janus Kinase 2 Proto-Oncogene Proteins c-met Benzenesulfonates Extracellular Signal-Regulated MAP Kinases Focal Adhesion Kinase 1 Receptor, erbB-2 Receptors, Platelet-Derived Growth Factor Cholesterol Ester Transfer Proteins Adaptor Proteins, Signal Transducing Niacinamide Cell Cycle Proteins Protein Phosphatase 1 Morpholines Cyclic AMP DNA Primers Androstadienes Proton-Translocating ATPases RNA, Small Interfering Membrane Proteins Transcription Factors Phosphotransferases (Alcohol Group Acceptor)Peptides Phospholipase C gamma Chromones Flavonoids Type C Phospholipases Receptor, Platelet-Derived Growth Factor beta Protease Inhibitors Cinnamates p21-Activated Kinases Indole Alkaloids rho-Associated Kinases MAP Kinase Kinase 1 Nuclear Proteins DNA, Complementary NF-kappa B Carbazoles Peptide Fragments Angiogenesis Inhibitors CDC2 Protein Kinase STAT3 Transcription Factor Phthalazines Aurovertins 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Trans-Activators Catechols Ribosomal Protein S6 Kinases Pyrazoles Cyclins Imidazoles Vascular Endothelial Growth Factor Receptor-2 Plant Proteins MAP Kinase Kinase Kinases Antibodies, Monoclonal Sulfonamides Tetradecanoylphorbol Acetate Ligands Trypsin Inhibitors Tumor Suppressor Proteins Receptor, Insulin Protein Tyrosine Phosphatase, Non-Receptor Type 11 Hydroquinones Protein Kinase C-delta Neoplasm Proteins Receptor, Platelet-Derived Growth Factor alpha Oncogene Proteins v-abl Aurora Kinases Casein Kinase II Androgen-Binding Protein Receptor, IGF Type 1 Ubiquitin-Protein Ligases Proto-Oncogene Proteins c-raf Complement C1 Inactivator Proteins Creatine Kinase Platelet-Derived Growth Factor Receptors, Growth Factor CDC2-CDC28 Kinases DNA Macromolecular Substances Cysteine Proteinase Inhibitors Casein Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Blotting, Western Transfection Models, Molecular Models, Biological Precipitin Tests Electrophoresis, Polyacrylamide Gel Immunoblotting Cloning, Molecular Reverse Transcriptase Polymerase Chain Reaction Xenograft Model Antitumor Assays Two-Hybrid System Techniques Mutagenesis, Site-Directed Immunohistochemistry Sequence Alignment Molecular Targeted Therapy Crystallography, X-Ray Inhibitory Concentration 50 Drug Design Drug Screening Assays, Antitumor

Phenomena and Processes46

Phosphorylation Signal Transduction Amino Acid Sequence Enzyme Activation Protein Binding Mutation MAP Kinase Signaling System Kinetics Drug Resistance, Neoplasm Transfection Protein Structure, Tertiary Apoptosis Dose-Response Relationship, Drug Binding Sites Base Sequence Cell Proliferation Cell Division Sequence Homology, Amino Acid Substrate Specificity Time Factors Sumoylation src Homology Domains Protein Conformation Cell Cycle Gene Expression Regulation Transcription, Genetic Protein Processing, Post-Translational Cell Survival Molecular Weight Structure-Activity Relationship Up-Regulation Gene Expression Down-Regulation Cell Movement Drug Synergism Inhibitory Concentration 50 Gene Expression Regulation, Neoplastic Cell Adhesion Genes, abl Genes, erbB-1 Cell Differentiation Transcriptional Activation Promoter Regions, Genetic Protein Transport Plasmids Gene Expression Regulation, Enzymologic

Disciplines and Occupations2

Immunohistochemistry Drug Design

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Small Molecule Libraries Protein Inhibitors of Activated STAT Protein Kinase Inhibitors Tyrosine Protein-Tyrosine Kinases Phosphorylation Enzyme Inhibitors Pyrimidines Signal Transduction Genistein Benzamides Quinazolines Phosphatidylethanolamine Binding Protein Receptor, Epidermal Growth Factor Piperazines Receptor Protein-Tyrosine Kinases src-Family Kinases Phosphatidylinositol 3-Kinases Molecular Sequence Data Tyrphostins Amino Acid Sequence Protein Kinases Antineoplastic Agents Enzyme Activation Protein Binding Protein-Serine-Threonine Kinases Cell Line, Tumor Indoles Proteins Cell Line Pyrroles Mutation MAP Kinase Signaling System Cells, Cultured Proto-Oncogene Proteins Phosphotyrosine Protein Kinase C 5-Lipoxygenase-Activating Protein Inhibitors Intracellular Signaling Peptides and Proteins Leukemia, Myelogenous, Chronic, BCR-ABL Positive Kinetics Protein Tyrosine Phosphatases Blotting, Western Calcium-Calmodulin-Dependent Protein Kinases Lactams, Macrocyclic Fusion Proteins, bcr-abl Drug Resistance, Neoplasm Quinones Transfection Benzoquinones Protein Structure, Tertiary Apoptosis Dose-Response Relationship, Drug Tumor Cells, Cultured Binding Sites Carrier Proteins Proto-Oncogene Proteins c-abl Isoflavones Phosphoproteins Base Sequence Mitogen-Activated Protein Kinases Cell Proliferation Mitogen-Activated Protein Kinase 1 Recombinant Proteins Thiazoles Cyclin-Dependent Kinase Inhibitor p27 Pyridines fms-Like Tyrosine Kinase 3 Recombinant Fusion Proteins Cell Division Proto-Oncogene Proteins c-kit Cyclic AMP-Dependent Protein Kinases SUMO-1 Protein Models, Molecular Small Ubiquitin-Related Modifier Proteins RNA, Messenger Mitogen-Activated Protein Kinase 3 Cattle Cyclin-Dependent Kinases p38 Mitogen-Activated Protein Kinases Quinolines Sequence Homology, Amino Acid Proto-Oncogene Proteins pp60(c-src)Phenylurea Compounds Calcium Staurosporine Substrate Specificity Lung Neoplasms Vanadates Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Time Factors Cyclin-Dependent Kinase Inhibitor p21 Mitogen-Activated Protein Kinase Kinases Proto-Oncogene Proteins c-akt Tyrosine 3-Monooxygenase Epidermal Growth Factor Nitriles Sumoylation Models, Biological Phosphoprotein Phosphatases

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