• Rickettsia conorii are known as a cause of "Mediterranean spotted fever, Astrakhan fever, Israeli spotted fever, and Indian tick typhus in the Mediterranean basin and Africa, Southern Russia, Middle East, and India, respectively. (kenyon.edu)
  • Below are tables of different groups of Ricketsia along with the diseases that each species cause and their general geological distribution. (kenyon.edu)
  • In rare cases, murine typhus can lead to severe systemic complications such as acute renal failure, interstitial pneumonia, and complications of the central nervous system. (cdc.gov)
  • Murine typhus is found throughout the world, widely distributed in subtropical and tropical regions, and is most apparent in port cities with large rat populations ( 2 , 4 ), which provide a reservoir for the pathogen and its main vector, the rat flea (X enopsylla cheopsis ). (cdc.gov)
  • In the landlocked northern Tanzanian town of Moshi, murine typhus was detected in 0.5% of febrile patients ( 6 ). (cdc.gov)
  • A predictive risk model for endemic typhus based on environmental conditions has not been established, but because plague is also transmitted by X. cheopsis fleas, some of the findings regarding plague transmission might also apply to murine typhus. (cdc.gov)
  • The established reservoirs of murine typhus are Rattus spp. (cdc.gov)
  • (cdc.gov)
  • Traditionally, we think of rats as the main host for this infection, which is why the common name of the disease is murine typhus. (cdc.gov)
  • Kristy Murray] Well, we began hearing about new cases of murine typhus that were locally acquired in the Houston area, and that was really unusual considering the last reported case was several decades ago. (cdc.gov)
  • So we went through and analyzed these data over a ten year period to better understand the "when, where, and who" of murine typhus across the state. (cdc.gov)
  • Kristy Murray] All cases are passively reported, so we rely first on the patient to present for medical care, then for the medical community to actually suspect a case of murine typhus, request the right kind of diagnostic tests, and then report the case to the local health department if the results come back positive. (cdc.gov)
  • The principle diseases of this group are epidemic or louse-borne typhus and its recrudescent form known as Brill-Zinsser disease, murine typhus, and scrub typhus . (medscape.com)
  • Murine typhus and scrub typhus share the same pathophysiology as epidemic typhus, although they are somewhat milder. (medscape.com)
  • Most cases of murine typhus in Texas occur in spring and summer, whereas, in California, the illness is most common in the summer and fall. (medscape.com)
  • In 2013, 12 patients with murine typhus were identified in Galveston, Texas, which may reflect a re-emergence of R typhi in the rat population and/or a cycle involving opossums and cats with R felis . (medscape.com)
  • [ 4 ] Murine typhus is most common in adults, but infection may occur in any age group. (medscape.com)
  • We further characterized novel sRNAs from typhus ( R. prowazekii and R. typhi ) and spotted fever ( R. rickettsii and R. conorii ) groups for their promoters and Rho-independent terminators using Bacterial Promoter Prediction Program (BPROM) and TransTermHP prediction algorithms, respectively. (biomedcentral.com)
  • This review highlights a diverse group of obligate intracellular bacterial pathogens that manipulate the host cytoskeleton to thrive within eukaryotic cells and discusses underlying molecular mechanisms that promote these dynamic host-pathogen interactions. (frontiersin.org)
  • Flea-borne typhus cases still occur in certain areas of the country, including California, Hawaii, and Texas. (cdc.gov)
  • During World War I , an estimated three million deaths occurred in Russia and more in Poland and Romania , and thousands of prisoners held in the appalling conditions in Nazi concentration camps died of typhus during World War II . (newworldencyclopedia.org)
  • Even in the absence of an available vaccine in some Third World countries, typhus is a largely preventable disease, with prevention tied to personal and social responsibility. (newworldencyclopedia.org)
  • Check with your state or local health departments to learn if flea-borne typhus is reportable in your state and, if applicable, what the current case counts are in your area. (cdc.gov)