• Rickettsia felis is an obligate intracellular bacterium belonging to the spotted fever group, suspected to cause a murine typhus-like illness in humans, with a cosmopolitan distribution. (biomedcentral.com)
  • In the United States, a drastic increase of murine typhus in the 1940s, Rocky Mountain spotted fever (RMSF) in the late 1970s, and the human ehrlichioses in the 1990s attests to the potential emergence of these infections in populations at risk (3) . (cdc.gov)
  • Composite diagram of the life cycle of Rocky Mountain spotted fever, rickettsialpox, and murine typhus. (cdc.gov)
  • Although rickettsiae have a symbiotic relationship with their arthropod hosts, in some instances, they act as true parasites-for example, members of the Wolbachia and Orientia tsutsugamushi alter reproduction and manipulate cellular processes in their arthropod hosts (4) , and the agent of epidemic typhus, Rickettsia prowazekii , kills its vector, the human body louse (5) . (cdc.gov)
  • Rickettsia conorii are known as a cause of "Mediterranean spotted fever, Astrakhan fever, Israeli spotted fever, and Indian tick typhus in the Mediterranean basin and Africa, Southern Russia, Middle East, and India, respectively. (kenyon.edu)
  • The aim of the present study was to obtain further information on the occurrence and distribution of R. felis in fleas from different Italian regions, where the presence of this agent is still unknown. (biomedcentral.com)
  • Rickettsial diseases, important causes of illness and death worldwide, exist primarily in endemic and enzootic foci that occasionally give rise to sporadic or seasonal outbreaks. (cdc.gov)
  • Consequently, coevolution of rickettsiae with arthropods is responsible for many features of the host-pathogen relationship that are unique among arthropod-borne diseases, including efficient pathogen replication, long-term maintenance of infection, and transstadial and transovarial transmission. (cdc.gov)
  • Prevalence differences in relation to host species (cats and dogs), provenance and flea sex were tested by χ 2 test or Fisher's Exact test using the SPSS statistical package (SPSS Inc., USA) for Windows, version 15.0. (biomedcentral.com)