Type backbone peptide nucleic acids. Medical search. Frequent questions

The process includes reacting amino acid with a nosyl group. (amrita.edu)
The nosyl protected amino acid is alkylated with 2-(Boc-amino)ethyl bromide to obtain an intermediate. (amrita.edu)
Such reactions employ agents that act by hydrolysis of peptide bonds and the specificity of the cleavage agent is determined by the identity of the amino acid residue at or near the peptide bond which is cleaved. (justia.com)
Backbone modifications for enhanced cellular uptake: For enhanced cellular delivery, PNA has been conjugated with cell penetrating peptide (CPP), cationic peptides, and basic amino acid stretches such as Lysine and Arginine. (creative-peptides.com)
b) Amino acid sequence and the CCHC zinc … To day only little is known within the structure stoichiometry NCp-NCp relationships and chaperone activity as it relates to G-quadruplex constructions the searching mechanism for the prospective sequence and so on. (techuniq.com)
alanine (Ala, A) - Alpha amino acid with a non-polar side chain. (rcsb.org)
alignment - A comparison of two or more gene or protein sequences in order to determine their degree of similarity in amino acid or bases, respectively. (rcsb.org)
For example, the backbone carbon atom linked to the carbonyl group in an alpha amino acid, to which the side chain is attached. (rcsb.org)
It is characterized by hydrogen bonds between the carbonyl group (-C=O) of one amino acid and the amino (N-H) group of the amino acid 4 residues below it along the helix. (rcsb.org)
amino acid - A building block of proteins is an alpha amino acid which contains a basic amino group, an acidic carboxyl group, and a hydrogen or organic side chain attached to the central carbon atom. (rcsb.org)
The C-group of one amino acid binds to the N-group of another. (slideshare.net)
Here, the amino acid sequences of eryngitin 3 and 4, RL-Ps isolated from Pleurotus eryngii fruiting bodies, were determined to (i) obtain structural information on this specific ribonuclease family from edible mushrooms and (ii) explore the structural determinants which justify their different biological and antipathogenic activities. (bvsalud.org)
An amino acid is the fundamental molecule that serves as the building block for proteins. (genome.gov)
A codon is a DNA or RNA sequence of three nucleotides (a trinucleotide) that forms a unit of genetic information encoding a particular amino acid. (genome.gov)
Each time an amino acid is added to a growing polypeptide during protein synthesis, a tRNA anticodon pairs with its complementary codon on the mRNA molecule, ensuring that the appropriate amino acid is inserted into the polypeptide. (genome.gov)
Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. (embl.de)
Mammalian and avian cysteine-rich protein (CRP), a 192 amino-acid protein of unknown function. (embl.de)
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. (transectscience.org)
A linear chain of amino acid residues is called a polypeptide. (transectscience.org)
The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. (transectscience.org)
The sequence of amino acid residues in a protein is defined by the sequence of a gene which is encoded in the genetic code. (transectscience.org)
Read in groups of three, the base sequence directly gives the amino acid sequence in the encoded protein. (rainis.pics)
The ionizable amino acid side chains of proteins are usually located at the surface. (lu.se)

The four main classes of organic compounds (carbohydrates, lipids, proteins, and nucleic acids) that are essential to the proper functioning of all living things are known as polymers or macromolecules. (baahkast.com)
Proteins, carbohydrates, nucleic acids, and lipids are the four major classes of biological macromolecules-large molecules necessary for life that are built from smaller organic molecules. (baahkast.com)
Glycerol is a three-carbon molecule that functions as the backbone of these membrane lipids. (baahkast.com)
Conjugation of oligonucleotides with fluorophores (fluoresceine, Cy3, Ct5, etc..) and other types of small molecules such as biotine, lipids. (nanbiosis.es)

The disclosure in various embodiments is related to a peptide nucleic acid monomer (VI) and an improved process for preparation of PNA (VI) using nosyl-group containing starting material. (amrita.edu)
The PNA backbone upon addition of a modified nucleobase results in the formation of a PNA monomer (VI). (amrita.edu)
Building on previous research, representative nucleic acid duplexes were split into logical monomer segments, and atomic coordinates were used to create solid models for 3D printing. (allenpress.com)
Monomer for Me-phosphonate nucleic acid synthesis. (biosearchtech.com)
One nucleic acid monomer, ATP, is also life's key energy currency. (learn-biology.com)

It binds nucleic acids through electrostatic relationships of the basic residues (especially those in the N-terminal sequence and the linker) with the phosphodiester backbone of nucleic acids. (techuniq.com)
Methyl phosphonoamidites are deoxynucleoside amidites modified such that, when incorporated into an oligonucleotide, that base position will have a (electrically neutral) methyl phosphonate backbone linkage instead of the standard (negatively charged) phosphodiester linkage. (genelink.com)
The sugars and phosphates in nucleic acids are connected to each other in an alternating chain, linked by shared oxygens, forming a phosphodiester functional group. (wikidoc.org)
In the more common B form, the DNA helix has a repeat of 10.5 base pairs per turn, with the sugar and phosphate forming the covalent phosphodiester "backbone" of the molecule, and the bases adenine, guanine, cytosine and thymine line up in the middle, where the base pairs we know today are, which look like the rungs of a ladder. (rainis.pics)

active site - A region in proteins and nucleic acids (that participate in chemical reactions), where reacting molecules (substrates) bind and make specific contacts necessary for chemical catalysis. (rcsb.org)
Experimental methods of multi-dimensional NMR spectroscopy, dynamics and theoretical description of spin system evolution, multiple resonance NMR technique for structural studies of proteins and nucleic acids by NMR spectroscopy, contemporary methods of structural biology, studies of complex biomolecular systems. (muni.cz)

With few exceptions, cellular membranes - including plasma membranes and internal membranes - are made of glycerophospholipids, molecules composed of glycerol, a phosphate group, and two fatty acid chains. (baahkast.com)
Recently PNAs, because of their excellent affinity to DNA/RNA and the scope to be modified as per the application, have attracted a wide range of researchers for the development of new PNA molecules by a simple backbone or nucleobase modifications. (creative-peptides.com)
In the broadest sense, Peptidomimetics are organic molecules which mimic some properties of natural peptide ligands. (ijpsr.com)
They are designed by either making changes in an existing peptide or by designing similar molecules that functional equivalence to peptides 12 . (ijpsr.com)
Molecules containing both aromatic peptides and nucleic acids could in principle exploit different forces to self-assemble. (cnr.it)
Nucleic acids are the molecules of genetics and heredity, and includes DNA and RNA. (learn-biology.com)
Nucleic acids, DNA and RNA, can be considered as the information molecules of the cell. (rainis.pics)

The technology known as triplex-forming peptide nucliec acids (PNAs) are a DNA mimic that involve bases modified with polyamide backbones that are resistant to degradation and can target and bind sequence where it induces site specific recombination with a donor template. (epigenie.com)
The importance of peptide nucleic acids (PNAs) for alteration of gene expression is nowadays firmly established. (unife.it)
PNAs are characterized by a pseudo-peptide backbone composed of N-(2-aminoethyl)glycine units and have been found to be excellent candidates for antisense and antigene therapies. (unife.it)
Peptide nucleic acids (PNAs) 1 are synthetic structural homologues of DNA and RNA in which the entire phosphate-sugar backbone of the polynucleotide has been replaced by a flexible polyamide backbone consisting of 2-aminoethyl glycine units. (archive.org)

What are the 4 types of macromolecules? (baahkast.com)
Within individual cells, there exist thousands of different types of macromolecules, or organic compounds. (baahkast.com)
Macromolecules - proteins, nucleic acids, and polysaccharides - are formed by the polymerization of hundreds of their low-molecular-weight precursors - amino acids, nucleotides, and simple sugars. (baahkast.com)
Nucleic acids are the most important macromolecules for the continuity of life. (libretexts.org)
Like other biological macromolecules such as polysaccharides and nucleic acids, proteins are essential parts of organisms and participate in virtually every process within cells. (transectscience.org)

A significant of quadruplex-forming oligonucleotides and their improved counterparts have already been proven to inhibit the experience of HIV-1 integrase an enzyme which is in charge of the integration of viral DNA into web host genome.20 Also the locked and intercalating nucleic acids with the capacity of forming G-quadruplex framework have already been reported to possess improved anti-HIV-1 activity. (techuniq.com)
It has been used to label oligonucleotides with fluorescent dyes, sugars, peptides and other reporter groups, to cyclise DNA, to synthesise DNA catenanes, to join oligonucleotides to PNA, and to produce analogues of DNA with modified nucleobases and backbones. (ox.ac.uk)
Nucleoside phosphate backbone modifications are useful for increasing the stability of oligonucleotides duplexes and expanding the library of potential conjugates. (biosearchtech.com)
Many oligo backbone modifications create unique binding capabilities and bolster sequence discrimination, making them useful for a variety of diagnostic and therapeutic applications such as SNP genotyping, antisense oligonucleotides, siRNA, and cell delivery. (biosearchtech.com)
For Anion as well as Cation Exchange Chromatography, the product line contains methacrylate-based and silica-based columns for the analysis of proteins, peptides, DNA- and RNA- derived oligonucleotides and other nucleic acid fragments. (tosohbioscience.com)

With the SAV, 'targeting warheads' may potentially include different types of antigens including proteins, peptides, polysaccharides or nucleic acids. (keloland.com)

According to the company's website, its xenonucleic acids can be in the form of peptide nucleic acids, glycol nucleic acids, or another suitable modified backbone. (genomeweb.com)
Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). (wikidoc.org)

Finally, the same tools used to create these models can be readily applied to other types of backbones and nucleobases for endless research and education possibilities. (allenpress.com)
However, these issues can be overcome by the chemical flexibility of PNA that allows for the insertion of modifications on its backbone and nucleobases. (creative-peptides.com)

P. Ramani, "Peptide Nucleic Acid monomers and a preparation method thereof", U.S. Patent 2017410201932017. (amrita.edu)
In the structural modification of PNA, there are few types of base modification, mainly the introduction of monomers composed of pseudocytosine, in order to make the modified peptide nucleic acid and DNA form a triple helix without pH dependence. (creative-peptides.com)
The monomers from which nucleic acids are constructed are called nucleotides . (wikidoc.org)
Ribonucleic acid, or RNA, is a nucleic acid polymer consisting of nucleotide monomers, which plays several important roles in the processes of translating genetic information from deoxyribonucleic acid (DNA) into proteins. (wikidoc.org)
a]Nitrogen is found in amino acids, the monomers of proteins, and in the nitrogenous bases that make up nucleotides (the monomers of nucleic acids). (learn-biology.com)

Ribonucleic Acid (RNA) 2.1. (slideserve.com)
The most common nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). (wikidoc.org)

In known Earth-based life, amino acids are almost universally of the L form and sugars are of the D form. (wikipedia.org)
Polystyrene-based ion exchange columns are available for analyzing low MW sugars, amino acids, nucleic acid bases, and small drug candidates. (tosohbioscience.com)

Thermo Scientific Acclaro Intelligence Technology software (standard in our premier NanoDrop One/One C and NanoDrop Eight spectrophotometers) uses full-spectrum data and advanced algorithms to identify common nucleic acid contaminants and provide corrected nucleic acid concentrations. (thermofisher.com)

Generate oligos with a neutral backbone that assists in binding DNA, RNA and double-stranded DNA. (biosearchtech.com)
Nucleic acids are usually either single-stranded or double-stranded, though structures with three or more strands can form. (wikidoc.org)
A double-stranded nucleic acid consists of two single-stranded nucleic acids held together by hydrogen bonds , such as in the DNA double helix. (wikidoc.org)

Creative Peptides has provided many years of professional support to local, domestic and international customers. (creative-peptides.com)
As a research organization that provides full-service PNA services, Creative Peptides ' customer-centric collaborative approach helps us build true partnerships with customers. (creative-peptides.com)

Nucleic acid types differ in the structure of the sugar in their nucleotides - DNA contains 2- deoxyriboses while RNA contains ribose . (wikidoc.org)
Proteins were known to be composed of 20 distinct amino acids whereas DNA is composed of only 4 nucleotides. (proprofs.com)
In the early twentieth century, it was believed that proteins might carry genetic information because proteins were known to be composed of 20 distinct amino acids, whereas DNA is composed of only 4 nucleotides. (proprofs.com)
Which type of bonds link the individual nucleotides together in DNA? (proprofs.com)

He observed that the structure of a naturally occurring Opioid molecule: Morphine was similar to N-terminal structure of endogenous opioid peptides, Enkephalins and β-endorphin. (ijpsr.com)
Allostery - This is a type of effect seen in proteins where the binding of a molecule, ion etc. to one location can have an impact of the structure and interactions at another location. (rcsb.org)
Each of these is distinguished from naturally-occurring DNA or RNA by changes to the backbone of the molecule. (wikidoc.org)
RNA acts as a messenger between DNA and the protein synthesis complexes known as ribosomes, forms vital portions of ribosomes, and serves as an essential carrier molecule for amino acids to be used in protein synthesis. (wikidoc.org)
Phosphorus is found in the sugar-phosphate backbone of nucleic acids, in phospholipids, and in the energy transfer molecule ATP. (learn-biology.com)

Tom Brown presented the chemical ligation of DNA by "click"-type chemistry and Thomas Carell talked about unusual bases in our genome and their epigenetic functions. (beilstein-institut.de)
Other rare nucleic acid bases can occur, for example inosine in strands of mature transfer RNA . (wikidoc.org)
Nitrogenous bases found in nucleic acids include adenine and guanine (called purines) and cytosine, uracil, or thymine (called pyrimidines). (rainis.pics)

We therefore synthesized conjugates of the peptide FF to the peptide nucleic acid dimer "gc" and characterized their aggregates by different spectroscopic techniques, including NMR, CD and fluorescence. (cnr.it)
Hiroyuki Asanuma followed this path by a report on threolinol and serinol nucleic acid analogs and Jesper Wengel extended the topic by peptide-nucleic acid conjugates. (beilstein-institut.de)

Deoxyribonucleic Acid (DNA) 1.1. (slideserve.com)
Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms. (wikidoc.org)

Backbone modification and Hybridization properties: Hence the enhancement of binding affinity and sequence specificity of PNA for DNA and RNA complement via chemical modification of PNA backbone is highly desirable and will have significant contribution for potential application in therapeutics and diagnostics. (creative-peptides.com)

Each unit is linked to an appropriate purine or pyrimidine base to create the sequence required for hybridization to the targeted nucleic acid (1-3). (archive.org)
In the first session "new nucleic acid building blocks", Annemieke Madder reported on modified nucleic acids for crosslinks and Elmar Weinhold talked about sequence-specific labeling of DNA by methyltransferases. (beilstein-institut.de)
Aspects of the disclosure relate to compositions and methods for amplifying and/or detecting one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens) in a biological sample obtained from a subject. (justia.com)
The disclosure generally relates to methods for detecting the presence of a target nucleic acid sequence. (justia.com)
A protein consists of one or more chains of amino acids (called polypeptides) whose sequence is encoded in a gene. (genome.gov)
Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity. (transectscience.org)

Type and number of internal monosaccharides and their linkages determine fine specificity of virus receptors ( 19 , 20 ). (cdc.gov)

You can also input custom oligo sequences and the software will automatically calculate the factor to apply for nucleic acid quantification. (thermofisher.com)
LGC, Biosearch Technologies offers a wide range of high-quality amidites and reagents for modifying oligo backbones-all available in popular pack sizes and packaging formats, and most are available in bulk quantities. (biosearchtech.com)
We are constantly growing our portfolio of amidites and solid supports for incorporating oligo backbone modifications, and we listen to what our customers need. (biosearchtech.com)
Hydrophilic polymer-based, exchange columns packed with non-porous resin particles are available for the separation of proteins, protein aggregates, charge isomers of monoclonal antibodies, PEGylated proteins, DNA fragments, nucleic acids, oligo DNA, and siRNA. (tosohbioscience.com)

Addition of D -alanine to TAs reduces the negative charge of the cell envelope thereby preventing cationic antimicrobial peptides (CAMPs) from reaching their target of action on the bacterial surface. (frontiersin.org)

Silicon, unlike carbon, lacks the ability to form chemical bonds with diverse types of atoms as is necessary for the chemical versatility required for metabolism, and yet this precise inability is what makes silicon less susceptible to bond with all sorts of impurities from which carbon, in comparison, is not shielded. (wikipedia.org)
in case of nucleic acids, Watson-Crick pairing drives self-assembly while, in case of peptides, backbone hydrogen bonds and interactions between aromatic side chains trigger the formation of structures, such as nanotubes or ribbons. (cnr.it)
We call these bonds peptide bonds. (slideshare.net)

High delivery efficiency, low cytotoxicity, maintenance of the PNA biological activity, and easy preparation makes this vector a candidate for a universal delivery system for this class of nucleic acid analogs. (unife.it)

Short polypeptides, containing less than 20-30 residues, are rarely considered to be proteins and are commonly called peptides, or sometimes oligopeptides. (transectscience.org)
Solvent- accessible surface representation colored by residue type (acidic residues red, basic residues blue, polar residues green, nonpolar residues white). (transectscience.org)
To examine the role of water penetration, we have measured the 17O and 2H magnetic relaxation dis- persions (MRD) for the V66E and V66K mutants of staphylococcal nuclease, where glutamic acid and lysine residues are buried in predominantly apolar environments. (lu.se)

Although nucleic acid chemistry seems to be already a mature part of organic and bioorganic chemistry, actual questions that are raised by research in biology and chemical biology give enough reasons to synthesize new nucleic acid probes and thereby further develop nucleic acid chemistry. (beilstein-institut.de)
The single session on Thursday was focused on light-driven and fluorescent functionalities and started with Nathan Luedtke talking about biorthogonal fluorescent reporters for nucleic acids in cells and Oliver Seitz focusing on enhanced hybridization probes for RNA imaging. (beilstein-institut.de)

Carbohydrates, nucleic acids, and proteins are often found as long polymers in nature. (baahkast.com)

The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. (justia.com)
The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polypeptide released under the appropriate conditions. (justia.com)
Polymer: Protein or polypeptide - A peptide is a chain of amino acids, so a polypeptide is several chains put together. (slideshare.net)

Peptide nucleic acid (PNA) is an artificial oligonucleotide mimetic with a peptidic backbone in lieu of a phosphoribosyl backbone. (creative-peptides.com)
This study presented an artificial intelligence pipeline of miRNA-based discovery of biomarkers, therapeutic targets, and repositioning drugs that can be applied to many cancer types. (cdc.gov)

As more research labs and classrooms dive into the field of structural nucleic acid nanotechnology, students and researchers need access to interactive, dynamic, handheld models. (allenpress.com)
3-10 helix - A type of protein secondary structural element that is more tightly coiled than the alpha helix (3 amino acids per turn with 10 atoms in the ring completed by each intra-helical hydrogen bond). (rcsb.org)

Localized RNA backbone reversals stabilized by arginine-guanine interactions place the adenosines and guanines in reverse order in the duplex. (rcsb.org)

clinicians require high-resolution data on gene expression, but in standard real-time PCR and sequencing methods, unless a mutated gene makes up at least 10 percent of a sample, its signal is often swamped by super-abundant wild-type DNA. (genomeweb.com)
Because of its antigene, antisense, anti-miR, and the scope to be labeled with various fluorophores, PNA finds application in gene expression modulation in-vivo , and development of nucleic acid-based biosensors which are useful in biotechnology researches and clinical diagnostics. (creative-peptides.com)

A veteran of Boehringer Mannheim and Roche Diagnostics, Powell helped develop the XNA method, which binds wild-type DNA "like Velcro," he said. (genomeweb.com)

The symposium has been inspired by the thematic issue " Nucleic Acid Chemistry " in the Open Access Beilstein Journal of Organic Chemistry, edited by Hans-Achim Wagenknecht. (beilstein-institut.de)
The Beilstein Organic Chemistry Symposium 2016 was inspired by the Thematic Series "Nucleic acid chemistry" in the Beilstein Journal of Organic Chemistry. (beilstein-institut.de)
Since the discovery of solid-phase DNA (and later RNA) synthesis by methods of organic chemistry, the field of nucleic acid chemistry exploded. (beilstein-institut.de)
Specialty columns are available for organic acids by ion-exclusion (OApak-A and SCX) and mono- and disaccharides (Sugar AXI and Sugar AXG). (tosohbioscience.com)

Some amino acids can be synthesized in the body, but others (essential amino acids) cannot and must be obtained from a person's diet. (genome.gov)
In animals, proteins are needed in the diet to provide the essential amino acids that cannot be synthesized. (transectscience.org)

The backbone atoms of the peptide in this region forms a right handed helical structure, hence the name. (rcsb.org)
Replace non-bridging oxygen atoms with sulphur atoms to facilitate the attachment of site-specific reporter groups onto the DNA or RNA backbone or to create thioaptamers. (biosearchtech.com)

Dynamic and flexible nucleic acid models can provide current and future scientists with physical intuition for the structure of DNA and the ways that DNA and its synthetic mimics can be used to build self-assembling structures and advanced nanomachines. (allenpress.com)
Therefore, from a past few decades there have been extensive research in designing synthetic peptides and proteins for health care 4- 5 . (ijpsr.com)

The cell wall of gram-positive bacteria contains highly charged anionic polymers called teichoic acids (TAs) that consist of alditol phosphate repeats. (frontiersin.org)
Structurally, eryngitin 3 and 4 consist of 132 amino acids, most of them identical and exhibiting a single free cysteinyl residue. (bvsalud.org)
Highly divergent hypotheses have been put forward regarding the makeup of the prions, including that they consist of nucleic acid only or protein only, are lacking both protein and nucleic acid, or are a polysaccharide. (medscape.com)

Peptides and nucleic acids can self-assemble to give supramolecular structures that find application in different fields, ranging from the delivery of drugs to the obtainment of materials endowed with optical properties. (cnr.it)
Pol II, assisted by the neurodegeneration-associated enzyme senataxin, generates a shield comprising triplex nucleic acid structures known as R-loops at intergenic spacers flanking nucleolar rRNA genes. (nature.com)

In addition to modifying the PNA backbone, people have also modified the base part of the PNA to improve the biological activity of the modified PNA, in order to expand the application prospects and specificity of PNA. (creative-peptides.com)
defined Peptidomimetics as "compounds whose essential elements (pharmacophore) mimic a natural peptide or protein in 3D space and which retain the ability to interact with the biological target and produce the same biological effect" 14 . (ijpsr.com)

Tertiary: The entire chain of amino acids is bent and molded as needed, forming a sub-unit. (slideshare.net)

From Protein Complexes to Subunit Backbone Fragments: a Novel Approach to Native Mass Spectrometry. (chicagobiomedicalconsortium.org)

Backbone modifications of PNA (B = nucleobase) (Perera JDR, et al . (creative-peptides.com)

This methodology facilitates the isolation and recovery of the fusion peptide from the host cells by exploiting the physico-chemical properties of the fusion partner. (justia.com)

A randomly folded peptide nucleic acid has been transformed into a right-handed helix by simple modification at the γ-position of the backbone. (creative-peptides.com)
The helix makes one complete turn every 3.6 amino acids. (rcsb.org)

Intrigued by the fact that a non-peptide natural product was having the same effect as that of a natural peptide effector, Farmer hypothesized that other compounds might be discovered which will be non-Peptidic in nature but will "copy" or "mimic" naturally occurring proteins. (ijpsr.com)

We now offer several locked nucleic acid (LNA) phosphoramidites and CPGs, as well as methyl and ethyl phosphoramidites. (biosearchtech.com)

In some embodiments, the methods comprise isothermal amplification of a target nucleic acid and subsequent detection of the amplification products. (justia.com)
In some embodiments, compositions and methods described herein allow for direct application of amplification reactions including the nucleic acid reporters to immunoassay devices without any intervening fluid transfer or dilution steps. (justia.com)

With advances in UV-Vis software, researchers can now selectively quantify nucleic acid absorbance in the presence of chemical and nucleic acid contaminants . (thermofisher.com)
Andrea Rentmeister gave a chemical biology perspective on the 5'-cap and Snorri Sigurdsson described strategies for site-directed spin labeling of nucleic acids. (beilstein-institut.de)
Members of the institute have published in a wide range of peer-reviewed journals, including Nature, Molecular Cell, Angewandte Chemie, JACS, Science Advances, Proceedings of the National Academy of Sciences USA, Nucleic Acids Research, Chemical Science and many others. (le.ac.uk)

The open end timeline in the evening after dinner allowed intense discussions about all aspects of nucleic acids by PhD researchers, postdocs and junior professors together with the invited speakers. (beilstein-institut.de)

Anatomy1

Diseases2

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes10

Information Science3

Health Care1

Amino acid23

Lipids4

Monomer5

Phosphodiester4

Proteins and nucleic acids2

Molecules7

PNAs4

Macromolecules5

Oligonucleotides5

Polysaccharides1

Glycol nucleic2

Nucleobases2

Monomers5

RIBONUCLEIC ACID2

Sugars2

Common nucleic1

Double-stranded3

Creative Peptides2

Nucleotides4

Molecule5

Bases3

Conjugates2

Deoxyribonucleic2

Therapeutics1

Sequence6

Linkages1

Oligo4

Cationic1

Bonds3

Analogs1

Residues3

Probes2

Carbohydrates1

Polypeptide3

Artificial2

Structural2

Guanine1

Gene2

Binds1

Organic4

Essential amino2

Atoms2

Synthetic2

Consist3

Structures2

Biological2

Chain of amino1

Fragments1

Nucleobase1

Facilitates1

Helix2

Mimic1

Methyl1

Embodiments2

Chemical3

Researchers1