ThioredoxinsCarrier ProteinsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsGlucoseInsulin-Secreting CellsArrestinGliosisKetosisEnzyme ActivatorsHyperglycemiaTime-Lapse ImagingMAP Kinase Kinase Kinase 5Agouti-Related ProteinHomeostasisDiabetes Mellitus, ExperimentalReactive Oxygen Species3T3-L1 CellsHexosaminesBiosynthetic PathwaysOxidative StressMutation, MissenseHibernationOxidation-Reduction3-Hydroxybutyric AcidCCAAT-Binding FactorGene SilencingMice, KnockoutReverse Transcriptase Polymerase Chain ReactionDeoxyglucoseRNA, Small InterferingApoptosisEndoplasmic Reticulum StressCells, CulturedGene Expression RegulationProtein Array AnalysisAdiposityHypothalamusGlycolysisInsulinMice, Inbred C3HHuman Umbilical Vein Endothelial CellsAdipogenesisReal-Time Polymerase Chain ReactionInflammasomesGlucose Clamp TechniqueCodon, NonsenseCell LinePalmitic AcidMetforminChromatin ImmunoprecipitationPromoter Regions, GeneticVerapamilOleic AcidProtein StabilityProtein TransportAMP-Activated Protein KinasesAniline CompoundsDoxycyclineGene Knockdown TechniquesRNA, MessengerTandem Repeat SequencesBlood GlucoseHep G2 CellsBlotting, WesternCell Line, TumorCushing SyndromeSignal Transductionp300-CBP Transcription FactorsRNA InterferenceProteolysisFastingGene DeletionForkhead Transcription FactorsElectrophoretic Mobility Shift AssayOligonucleotide Array Sequence AnalysisUp-RegulationTranscription, GeneticInterleukin-1betaIn Situ Nick-End LabelingMice, Inbred C57BLEnergy MetabolismAmino Acid SubstitutionMitochondriaAmino Acid MotifsGene Expression ProfilingGene ExpressionDisulfidesRetinaInflammationHyperlipidemiasCell SurvivalHEK293 CellsEndothelial CellsLeptinAntioxidantsIslets of LangerhansCell NucleusGene Expression Regulation, NeoplasticInsulin ResistanceDiabetes Mellitus