At the molecular level, it was found that replacement of glucose by starch has enhanced the relative expression level of ccpA encoding catabolite control protein A. Therefore, the repression of starch utilization by glucose could be probably relieved. (hindawi.com)
Taken together, our data demonstrated that starch instead of glucose can promote colistin production probably by affecting the expression of colistin biosynthesis-related genes, as well as reducing the repression of glucose to a secondary metabolic product. (hindawi.com)
Because of its critical importance, the lac operonis only activated in the presenceolfactosewhen the favored carbon source, glucose,is absent (catabo- lite repression). (forextrading-madeeasy.com)
Transcription of the aml operon is significantly repressed in the wild type when growing on glucose and repression is absent in an Δ amlR deletion mutant. (frontiersin.org)
Accepted August 23, 2012 ABSTRACT The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydrates, like glucose in Gram-positive bacteria. (studyres.com)
Operon2
cAMP binds to catabolite activator protein (CAP) and together they will bind to a promoter sequence on the lac operon. (wikipedia.org)
G3P accumulates in the glpD mutant and represses lsr transcription by preventing cyclic AMP (cAMP)-catabolite activator protein (CAP)-dependent activation. (princeton.edu)
The requirement for cAMP-CAP in lsr activation explains why AI-2 persists in culture fluids of bacteria grown in media containing sugars that cause catabolite repression. (princeton.edu)
These findings show that, depending on the prevailing growth conditions, the amount of time that the AI-2 signal is present and, in turn, the time that a given community of bacteria remains exposed to this signal can vary greatly. (princeton.edu)
Repressor1
Note that E. coli has a similar cAMP-independent catabolite repression mechanism that utilizes a protein called catabolite repressor activator (Cra). (wikipedia.org)
Degradation1
Natural competence is regulated by at least three pathways in this organism: chitin sensing/degradation, quorum sensing and carboncatabolite repression (CCR). (biomedcentral.com)
Sugars1
These pre-treatments are designed to allow the carbohydrate portion of the biomass to be broken down into simple sugars, for example by en-zymatic hydrolysis using exogenously added cellulases to release fermentable sugars [ 12 ]. (banksolar.ru)
One such wide-domain regulatory circuit, essential to all cells, is carboncatabolite repression (CCR): it allows the cell to prefer some carbon sources, whose assimilation is of high nutritional value, over less profitable ones. (biomedcentral.com)
One such wide-domain regulatory circuit is carboncatabolite repression (CCR): it allows the preferred assimilation of carbon sources of high nutritional value over others [ 1 - 4 ]. (biomedcentral.com)
Mechanisms1
Determining the mechanisms of activation and repression for gltBDF was beyond the scope of this study. (biomedcentral.com)
Gene1
Catabolite repression is considered to be a part of global control system and therefore it affects more genes rather than just lactose gene transcription. (wikipedia.org)
Substances1
In addition, we found CRE1-repression of nitrogenous substances uptake, components of chromatin remodeling and the transcriptional mediator complex, as well as developmental processes. (biomedcentral.com)
Regulation1
Our study provides the first global insight into the molecular physiological response of a multicellular fungus to carbon catabolite regulation and identifies several not yet known targets in a growth-controlled environment. (biomedcentral.com)
Cell3
There are different catabolite-specific EIIA in a single cell, even though different bacterial groups have specificities to different sets of catabolites. (wikipedia.org)
In both cases, each genetically identical cell does not turn on, or express, the same set of genes. (pressbooks.pub)
Cells1
In turn, the N 2 fixation rate of single cells during NH 4 + limitation correlates positively with their growth rate after a shift to NH 4 + depletion, experimentally demonstrating the benefit of heterogeneity. (nature.com)
Present1
The iclR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60 amino acids present in transcription regulators of the iclR family, involved in carbon metabolism in eubacteria and archaea. (expasy.org)
Pathways1
These changes can, in turn, modify the metabolism of intestinal microbiota via the catabolite repression control pathways and other adaptive mechanisms. (medscape.com)
Note that E. coli has a similar cAMP-independent catabolite repression mechanism that utilizes a protein called catabolite repressor activator (Cra). (wikipedia.org)
The normal function of Ure2 protein is to turn off the uptake and utilization systems of nitrogen sources that don't support optimal growth when good nitrogen sources are available. (nih.gov)
This means that the gene is normally active and producing its corresponding protein, but can be turned off or repressed by the presence of a regulatory protein. (proprofs.com)
Streamlining Regulon Identification in Bacteria Regulons are a group of genes that can be turned on or off by the same regulatory protein. (doe.gov)
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy. (combichem.net)
Catabolite repression allows microorganisms to adapt quickly to a preferred (rapidly metabolizable) carbon and energy source first. (wikipedia.org)
The carbohydrate/nitrogen ratio and the nature of the carbon catabolites have a profound impact on the metabolism and byproducts of the microbiota. (medscape.com)
Synthesis1
Unlike the lac operon, it is also regulated by attenuation, in which mRNA synthesis that escaped repression by Trp is terminated before completion. (pharmacy180.com)
Bacterial2
There are different catabolite-specific EIIA in a single cell, even though different bacterial groups have specificities to different sets of catabolites. (wikipedia.org)
Whole genome sequencing of bacterial isolates has turn into a day by day job in lots of laboratories, producing unbelievable quantities of knowledge. (youngresearch.eu)
Control2
Catabolite repression is considered to be a part of global control system and therefore it affects more genes rather than just lactose gene transcription. (wikipedia.org)
In consequence, identification of the nature of pathogens, selection of the appropriate immune response, repression of damaging or inadequate immune response are now recognized as crucial steps for the successful control of an infectious event. (frontiersin.org)
Enzymes1
Our results indicate that sensing of N -acetyl- D -glucosamine induces GibS expression, which in turn modifies the transcript levels of metabolic enzymes. (nature.com)
Shown1
Turns out, it was later shown by Jan Wolff that potassium goes in with it. (nih.gov)
Researchers2
This in turn requires systems that allow researchers to quickly retrieve model predictions for visualization and analysis. (cdc.gov)
In previous work, the researchers showed that when Stat5 is turned on in primary prostate cancer, men are more likely to have recurrent disease. (combichem.net)