Tumours bone neoplasms. Medical search. Frequent questions

In conclusion, present study revealed that DEGs are directly involved in of breast tumor metastasis in bone tissues. (degruyter.com)
The tumor cell mass exerts mechanical pressure that can contribute to bone pain. (degruyter.com)
The microenvironment is fundamental in attracting tumor cells to the bone as well as promoting tumor progression. (degruyter.com)
The composition of the tumor microenvironment changes during tumor development, evolving to meet the demands of the growing neoplasm [ 6 ]. (degruyter.com)
A bone tumor, (also spelled bone tumour), is a neoplastic growth of tissue in bone. (icd.codes)
Micrograph of an osteosarcoma, a malignant primary bone tumor. (icd.codes)
Findings of other lesions indicates a non-bone primary tumor. (medscape.com)
Long term evolution of Paget's disease increases the risk of various malignant tumors like osteosarcoma, fibrosarcoma, chondrosarcoma, malignant fibrous histiocytoma and very rarely locally aggressive tumor like Giant Cell Tumour (GCT) [1]The reported cases of GCT complicating Paget's occur mainly in polyostotic disease [2]. (jocr.co.in)
In diagnosis of bone tumor, X-ray is as important, if not more important than pathology report. (jbstjournal.com)
X-ray, Bone tumor, Tumor mimics. (jbstjournal.com)
Extranodal Rosai-Dorfman disease presenting as incidental bone tumor: A case report. (jbstjournal.com)
It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Chondrosarcoma is the most common primary malignant bone tumor in patients older than 25 years [ 35 ]. (lww.com)
Two-dimensional (2D) tradition of cells from big cell tumor of bone (GCTB) is affected by lack of the multinucleated big cells in subsequent passages. (ncbcs.org)

Metastasis' look histologically identical to the primary tumour and are benign in nature. (wikipedia.org)
Bone-targeting properties of (223)Ra could also potentially be used for treating skeletal metastasis from other primary cancers. (researchgate.net)
The Enneking system for surgical staging of bone and soft tissue tumors is based on grade (G), site (T), and metastasis (M), and uses histologic, radiologic, and clinical criteria. (medscape.com)
Pathway-based biomarkers identification may help elucidate the cellular signature of breast cancer metastasis in bone, further characterizing the etiology and promoting new therapeutic approaches. (degruyter.com)
A total of 61 DEGs, included 27 down-regulated and 34 up-regulated, were found to be significant in breast cancer bone metastasis. (degruyter.com)
DEGs Bcl3, ADGRG7, FABP4, IRF4, their regulating miRNAs and TFs have strong impact on proliferation and metastasis of breast cancer in bone tissues. (degruyter.com)
Metastasis to bone typically results in a poor prognosis, reducing life expectancy to 2-3 years post-diagnosis. (degruyter.com)
38 patients underwent surgery for primary malignancy, 6 patients for benign tumour, while 5 patients had surgery for metastasis. (biomedcentral.com)
Patients 40 years old or older should undergo a workup for a potential bone metastasis. (medscape.com)
The prognosis is poor as the tumour is an aggressive tumour and have a high risk of metastasis. (ac.ir)
Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)

The diagnosis of OFC and Brown Tumours includes clinical symptoms involving chronic bone pain and laboratory findings of hyperparathyroidism. (unair.ac.id)
Based on the latest understanding of the mechanism of OFC, this review elaborates on the manifestation, diagnosis, and available therapies that can be leveraged to prevent the occurrence of OFC and Brown Tumours. (unair.ac.id)
Further endpoints include outcome stratification according to parameters as tumour site and tumour stage at diagnosis, as well as the identification of risk factors independently associated with worse survival. (emsos.org)
The approach to radiographic diagnosis of bone tumors goes far beyond conventional radiographs in the present era of multiplanar and functional imaging. (medscape.com)
In it is a misconception to believe that itive diagnosis is based on histology many lower-income countries, death cancer registry data can be auto- (although the proportion of cases for registration is confined to deaths in matical y derived from the health which the tumour is examined by the hospital (with no medical certification information system. (who.int)
The epigenetic basis of these giant cell-rich tumours is unclear and DNA methylation profiling has been shown to be clinically useful for the diagnosis of other tumour types. (bvsalud.org)
To code a diagnosis of this type, you must use one of the three child codes of C40.1 that describes the diagnosis 'malignant neoplasm of short bones of upper limb' in more detail. (icd.codes)
This paper provides a useful tool to assist in determining the diagnosis of benign neoplasms of the temporal bone using readily available imaging modalities. (entandaudiologynews.com)
Information from radiology, surgical, oncology and other clinical colleagues involved in the diagnosis and treatment of primary bone tumours should be properly assessed before undertaking a structured approach to specimen handling and histological reporting. (biomedcentral.com)
Staging procedures including CT of the abdomen and pelvis, bilateral bone marrow aspiration, and biopsies were within normal limits precluding the diagnosis of primary cerebral lymphoma. (bmj.com)
C41.3 is a billable ICD code used to specify a diagnosis of malignant neoplasm of ribs, sternum and clavicle. (icd.codes)
The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion regarding terminology and the criteria for its diagnosis. (ijsr.net)
Bone biopsy from the iliac region revealed numerous multinucleated giant cells with haphazard new bone formation and diagnosis of polyostotic Paget's disease was confirmed. (jocr.co.in)
HR+ (local lab results at screening or, if not available, at the time of diagnosis) To fulfil the requirement of HR+ disease, the primary tumour or metastatic lesion of the breast cancer must express at least one of the hormone receptors (estrogen receptor [ER] or progesterone receptor [PgR]) by immunohistochemistry (IHC). (researcherprofiles.org)
For all age groups, chemotherapy, having a bone sarcoma and having comorbidities were most frequently associated with low scores on HRQoL subscales, whereas a shorter time since diagnosis was not. (nih.gov)
Know the who, what and where of bone and soft tissue tumours and you will be a lot closer to making a diagnosis and a plan for investigations. (orthotumours.ca)
Primary bone and soft tissue tumours are a large and heterogeneous group of neoplasms, and we can get some guidance about what might be the diagnosis by knowing some of their predilections. (orthotumours.ca)

Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects. (ncbcs.org)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an especially uncommon tumour, which often impacts aged males and presents within the pores and skin with frequent involvement of the bone-marrow, peripheral blood and lymph nodes. (ncbcs.org)

UCLA Neoplasms Trial → Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. (researcherprofiles.org)
An Open Label, Phase Ib, Dose-escalation Study Evaluating the Safety and Tolerability of Xentuzumab and Abemaciclib in Patients With Locally Advanced or Metastatic Solid Tumours and in Combination With Endocrine Therapy in Patients With Locally Advanced or Metastatic Hormone Receptor-positive, HER2-, Breast Cancer, Followed by Expansion Cohorts. (researcherprofiles.org)
Solid tumours are abnormal masses of cells which may be non-cancerous (benign) or cancerous (malignant). (nihr.ac.uk)
Some solid tumours may be caused by specific genetic changes, for example, mutation in the NTRK genes, which can affect signalling inside the cell which drives cell growth. (nihr.ac.uk)
Hence, entrectinib offers the potential to treat many different types of solid tumours that are positive to the NTRK gene mutation. (nihr.ac.uk)
Multisite verification of the accuracy of a multi-gene next generation sequencing panel for detection of mutations and copy number alterations in solid tumours. (cdc.gov)

Trephine biopsies of the bone marrow should be carried out, when clinically indicated, by trained individuals following a standard operating procedure. (bmj.com)
A bone marrow aspiration should be performed as part of the same procedure. (bmj.com)
If bone marrow aspiration is found to be impossible, imprints from the biopsy specimen should be obtained. (bmj.com)
Ideally, reporting of trephine biopsy sections should be done by an individual who is competent in both histopathology and haematology, and who is able to make an appropriate assessment of both the bone marrow aspirate and the trephine biopsy sections. (bmj.com)
Clinical details and the results of relevant laboratory tests including the blood count and blood film features must be known before a bone marrow biopsy is performed. (bmj.com)
Suspected bone marrow fibrosis. (bmj.com)
Need to study bone marrow architecture. (bmj.com)
Need to study bone structure or bone marrow blood vessels. (bmj.com)
In general, patients who have a hypocellular bone marrow or bone marrow fibrosis are likely to need a trephine biopsy for adequate assessment. (bmj.com)
Similarly, only a trephine biopsy shows the architecture of the bone marrow and permits the detection of an abnormal distribution of cells, bone marrow granulomas, and focal lymphoid infiltrates. (bmj.com)
Unexplained pancytopenia and an unexplained leucoerythroblastic blood film are indications for a trephine biopsy because they are likely to indicate bone marrow infiltration or fibrosis. (bmj.com)
Bone cancer metastases usually occur in the axial skeleton, in areas with active hematopoiesis and high red marrow content. (degruyter.com)
The mouse is the most sensitive species where the target organs are bone marrow, ovary and testis a NOAEL for repeat dose toxicity in the chronic studies has not been established due to neoplasia-related toxicity. (europa.eu)
Multiple myeloma (MM) is an incurable neoplasm caused by proliferation of malignant plasma cells in the bone marrow (BM). (huji.ac.il)
blood transfusion), spinal cord, lung cancer (oncology), respiratory cancer, radiology Background Multiple myeloma is a malignant proliferation of plasma cells mostly affecting the bone marrow and commonly presents with anaemia, hypercalcaemia, renal dysfunction, bone and skeletal involvement. (2011globalhealth.org)
4. Adequate organ and bone marrow functions. (who.int)
Incorporating genetic counseling into the evaluation of pediatric bone marrow failure. (cdc.gov)

According to the Enneking's classification, one patient had stage 1A tumour, one patient had stage 1B tumour, 6 patients had stage 2A tumours and 30 patients had 2B tumours. (biomedcentral.com)
The 2002 World Health Organisation (WHO) classification of bone tumours is recommended for histological reporting of bone tumours as it is well-recognised and widely employed internationally [ 3 ]. (biomedcentral.com)
In the recent fifth edition of the World Health Organization classification, similar to the recent update to the International Consensus Classification, the category was renamed to "myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions" and both classifications added novel subtypes with new JAK2 rearrangements (e.g. (nature.com)
WHO Classification of head and neck Tumours. (crossref.org)
WHO Classification of Tumours of the Urinary System and Male Genital Organs. (crossref.org)
WHO Classification of Tumours of the Central Nervous System. (crossref.org)
WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. (crossref.org)
WHO Classification of Tumours of Female Reproductive Organs. (crossref.org)
WHO Classification of Tumours of Soft Tissue and Bone. (crossref.org)
WHO Classification of Tumours of the Breast. (crossref.org)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. (crossref.org)
The International Agency for Research on Cancer (IARC), which produces and publishes the World Health Organization (WHO) Classification of Tumours series (also known as the WHO Blue Books), will soon publish a volume specifically focused on the classification of paediatric cancers - the first of its kind in the history of the series. (who.int)
The main features of each chapter of the inaugural WHO Classification of Paediatric Tumours volume are summarized in a new review article published in the journal Cancer Discovery . (who.int)
Prior to this upcoming volume, the WHO Classification of Tumours has dealt with tumour classification from a more strictly organ- or system-specific perspective, with each volume dedicated to a particular anatomical site (digestive system, breast, soft tissue and bone, etc.) and compiled by experts in the respective area. (who.int)
But the specific diagnostic and clinical challenges of childhood tumours require a different approach, so the first WHO Classification of Paediatric Tumours has been developed with a more integrated, cross-sectional perspective by experts in childhood cancer. (who.int)

The lesion has a tendency to expand the bony cortices because the slow growth rate of the lesion allows time for the periosteum to develop a thin shell of bone ahead of the expanding lesion. (wikipedia.org)
The lesion has the typical appearance of a unicameral bone cyst. (medscape.com)
It develops as a lytic lesion in the epiphysis of long bones which might spread to the metaphysis. (bvsalud.org)
However, a painful, swollen distal thigh with a destructive lesion on the X-ray is more likely to be a primary bone sarcoma in a child, and more likely to be a metastatic lesion in an elderly patient. (orthotumours.ca)

Within this deleted region the tripartite motif containing 13 (TRIM13, also termed RFP2) gene product has been proposed to be a tumour suppressor gene (TSG). (huji.ac.il)

In two dogs, skull defects were closed with a patient-specific implant created by additive manufacturing after excision of tumours of the skull. (thieme-connect.com)
Diagnostic arthroscopy is a rare but essential modality in such cases due to better visuals, complete tumour excision, and combination with adjuvant therapies. (bvsalud.org)
We briefly present this case of chordoma, discussing the symptoms and signs, the radiological features and management including excision and replacement of the defect with bone graft. (spinalsurgerynews.com)
Therefore, historically treatment generally has consisted of wide excision of the involved bone segment, with the goal of achieving negative margins because margin status is the most important physician-controlled factor associated with treatment [ 6, 33, 37, 44 ]. (lww.com)

Abnormal growths found in the bone can be either benign (noncancerous) or malignant (cancerous). (icd.codes)
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)

Osteitis fibrosa cystica (OFC) and Brown Tumours are two related but distinct types of bone lesions that result from the overactivity of osteoclasts and are most often associated with chronic kidney disease (CKD). (unair.ac.id)
Moreover, hotspot KRAS mutations were identified in these lesions, placing them in the spectrum of RAS-MAPK-driven neoplasms, which were until recently thought to be reactive lesions. (unair.ac.id)
OFC (Osteitis Fibrosa Cystica) and Brown Tumours, skeletal lesions commonly found in chronic kidney disease (CKD) patients, are influenced by various risk factors, such as age, sex, medications affecting calcium metabolism, and vitamin D deficiency. (rumahginjal.id)
The recently described involvement of KRAS mutations turned Brown Tumours from reactive lesions to potentially neoplastic lesions. (rumahginjal.id)
Additionally, GCG can morphologically closely resemble other giant cell-rich lesions, including non-ossifying fibroma (NOF), aneurysmal bone cyst (ABC), giant cell tumour of bone (GCTB), and chondroblastoma. (bvsalud.org)
Contrast-enhanced sagittal computed tomography (CT) scan images demonstrate an area of decreased attenuation within vertebrae, with destructive or lytic lesions in the bone and spinal cord compression at that level. (spinalsurgerynews.com)
1 B cell neoplasms other than multiple myeloma including non-Hodgkin's lymphomas, and acute and chronic leukaemias might also exhibit lytic bone lesions, hypercalcaemia, and monoclonal gammopathy via the particular actions of interleukin (IL-1), IL-6, or tumour necrosis factor-α secreted by the neoplastic B cell clone, but not reported previously secondary to a primary cerebral lymphoma. (bmj.com)
The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities: fibrous dysplasia and ossifying fibroma. (ijsr.net)
Peripheral cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. (ijsr.net)

The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
3. Histologically confirmed HR+/ HER2- breast cancer determined from the most recent tumour sample (primary or metastatic) per the American Society of Clinical Oncology and College of American Pathologists guideline. (who.int)

Canonically, OFC and Brown Tumours are caused by secondary hyperparathyroidism in CKD. (unair.ac.id)
Between 1996-2003, 49 patients (mean age 43 years) underwent pelvic tumour resections- 38 primary malignant tumours, 5 secondary tumours and 6 benign tumours. (biomedcentral.com)
the principles of specimen handling required for assessment of secondary bone tumours are similar. (biomedcentral.com)
Development of secondary neoplasm in PDB is a known but rare phenomenon. (jocr.co.in)
RDD rarely affects bone as a primary or even secondary form of the disease. (jbstjournal.com)

Positron emission tomography (PET) CT/PET MRI has further revolutionized imaging of bone tumors by providing details of anatomic and morphologic characteristics simultaneously and by combining whole body scan in the same sitting. (medscape.com)
A number of staging systems are used for bone tumors. (medscape.com)
6. Dorman HD, Czerniak B. Bone Tumors. (jbstjournal.com)
10. Miwa S, Otsuka T. Practical use of imaging technique for management of bone and soft tissue tumors. (jbstjournal.com)

Malignant peripheral nerve sheath tumour, osteosarcoma and chordoma were the subtypes of which survivors reported the lowest HRQoL scores in comparison with the norm. (nih.gov)

Some risk factors contributed to the occurrence of OFC and Brown Tumours, such as age, gender, comorbidities, and certain medications. (unair.ac.id)
Brown Tumours, being rare, lack sufficient understanding regarding their manifestation and treatment. (rumahginjal.id)

Pathology and Genetics of Skin Tumours. (crossref.org)

The aim was to determine whether EGFR protein expression contributes to the aggressiveness and recurrence potential of giant cell tumour of bone (GCTB), an osteolytic primary bone tumour that can exhibit markedly variable clinical behaviour. (ox.ac.uk)
This review is intended to provide histopathologists with guidelines for clinical assessment, specimen handling and diagnostic reporting of benign and malignant primary bone tumours. (biomedcentral.com)
Consistency in diagnostic evaluation with respect to both terminology and report content facilitates liaison at multidisciplinary bone tumour meetings and collaboration between cancer units and networks, as well as providing a common database for audit of the clinical, radiological and pathological aspects of bone tumours. (biomedcentral.com)
Primary benign and malignant bone tumours vary widely in their clinical behaviour and pathological features. (biomedcentral.com)

A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)

participation in an external quality assessment (EQA) scheme which includes bone tumour pathology is recommended. (biomedcentral.com)
Pathology and genetics of tumours of the digestive system / Stanley R. Hamilton, Lauri A. Aaltonen. (who.int)
Pathology and genetics of tumours of the nervous system / Paul Kleihues, Webster K. Cavenee. (who.int)
Pathology and genetics of tumours of the breast and female genital organs / edited by Fattaneh A. Tavassoli, Peter Devilee. (who.int)
Pathology and Genetics of Tumours of Endocrine Organs. (crossref.org)
Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. (crossref.org)

Primary Tonsillar Small Cell Neuroendocrine Carcinoma with Bone Metastases', Iranian Journal of Otorhinolaryngology , 34(4), pp. 195-198. (ac.ir)

Although paediatric tumours are uncommon, they are a leading cause of death due to disease in children. (who.int)
Mesenchymal tumours of the gastrointestinal tract (GIT) are uncommon. (bvsalud.org)

Of the 5 metastatic tumours, there was 1 colorectal cancer, 1 vulvar cancer, 1 renal cell cancer, 1 squamous cell cancer and one Lung cancer. (biomedcentral.com)

The alpha-emitter radium-223 ((223)Ra) is a bone-seeking radionuclide studied as a new treatment for patients with bone metastases from hormone-refractory prostate cancer. (researchgate.net)
patients with bone metastases from hormone-refractory prostate cancer. (researchgate.net)
Breast cancer metastases are most commonly found in bone, an indication of poor prognosis. (degruyter.com)
In this study, we explore different signaling pathways and associated molecular mechanisms of underlying primary breast cancer development, along with the formation of metastases in the bone. (degruyter.com)
Bone metastases are the most common site of distant metastases and can cause severe and disabling effects, including pain, spinal cord compression and pathologic fracture. (centerwatch.com)
Radiotherapy (RT) is an effective treatment for palliative patients with painful bone metastases. (centerwatch.com)
Therefore, single fraction radiation therapy (SFRT) is encouraged, but 20 Gy in 5 fractions is also allowed in this study, though should be chosen only in patients with a complicated bone metastases by fracture, neurological deficit (e.g. spinal cord compression), or a large soft tissue component. (centerwatch.com)
Currently, the standard of care in British Columbia for palliative patients with bone metastases is SUPR. (centerwatch.com)

En-bloc resection has been the most widely used treatment for grade 2-3 CS, whereas for patients with low-grade CS, curettage is safe and effective. (emsos.org)
Research: Is resection of tumours involving the pelvic ring justified? (biomedcentral.com)
This study assessed the functional, oncologic and surgical outcomes following pelvic tumour resection. (biomedcentral.com)
Extended intralesional treatment of Grade I intracompartmental chondrosarcomas of the long bones of the appendicular skeleton therefore appears safe with improved functional scores and decreased complications versus segmental resection and reconstruction. (lww.com)

this is usually evidenced by the type of connective tissue matrix formed by tumour cells. (biomedcentral.com)
SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)

Histopathology revealed the overall appearances of grade 1 chondrosarcoma with a tumour composed of lobules of cartilage of varying size separated by fibrous tissue (Figure 6 ). (biomedcentral.com)
Based on the decreased biologic aggressiveness of low-grade cartilage neoplasms, several studies have suggested intralesional treatment may be adequate for Grade I chondrosarcomas [ 1, 4, 12, 19, 38 ]. (lww.com)

The types, molecular characteristics, and pathogenesis of tumours occurring in children are unique, and paediatric neoplasms lack the genetic complexity seen in adult disease. (who.int)

Chondrosarcoma is one of the most frequent primary bone sarcoma. (emsos.org)

All primary malignant bone tumour cases should be discussed at a properly constituted sarcoma multidisciplinary team (MDT) meeting. (biomedcentral.com)

Even though chordomas usually are slow-growing tumours, they are locally aggressive with a tendency to infiltrate into adjacent tissues and organs. (spinalsurgerynews.com)
Most chordomas generally behave as intermediate-grade locally aggressive tumours which frequently recur and can metastasise. (biomedcentral.com)

Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
Nonsquamous cell cancers, including minor salivary gland cancers, sarcomas, and melanomas, account for the other half (see the histologic distribution of hard palate malignant neoplasms and the histologic types and frequencies of minor salivary gland neoplasms of the palate below). (medscape.com)

The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)

Given the fact that the proximal tibia is one of the most frequently affected locations for primary bone tumours, sufficient reconstruction of the adjacent knee joint is of importance. (emsos.org)
As the current literature provides few information on reconstruction-technique-dependent outcomes following surgery for bone and soft tissue neoplasms involving the proximal tibia, the current multicentre retrospective study may allow to draw further conclusions on how to best approach tumours at this specific anatomical location. (emsos.org)

A new subclass designated Gastrointestinal Stromal Tumours (GIST) is diagnosed based on the presence of a mutational over expression of c-kit protein that is thought to be critical in the pathogenesis of these tumours.This newclass of tumoursmay form the majority of gastrointestinal mesenchymal tumours. (bvsalud.org)
contrastswith what obtains in developed countries in the proportion of GIT mesenchymal tumours that are truly GIST. (bvsalud.org)

Some high-grade monomorphic tumours, (such as Ewing's sarcoma), and some other specific tumour types cannot be graded accurately in this way and the tumour grade is defined by the specific histological type or subtype. (biomedcentral.com)
Histological examination of the specimens revealed proliferation of nests and cords of compressed odontogenic epithelium immersed in a densely collagenized stroma, associated to a few irregular bone trabeculae. (bvsalud.org)
a minority of tumours with histological characteristics of GIST are CD117 negative and are classified asCD117 negativeGIST. (bvsalud.org)

Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone. (ox.ac.uk)
We present a functional analysis of TRIM13 using a loss-of-function approach, and demonstrate that TRIM13 downregulation decreases tumour cell survival as well as cell cycle progression and proliferation of MM cells. (huji.ac.il)

Acute joint or bone fracture: In case of acute injury, fracture or dislocation, massage may aggravate the condition. (phuket-massage.com)

Patients with hormone-refractory prostate cancer and bone pain needing external-beam radiotherapy were assigned to four intravenous injections of (223)Ra (50 kBq/kg, 33 patients) or placebo (31 patients), given every 4 weeks. (researchgate.net)
Xentuzumab in combination with abemaciclib and hormonal therapies The study also tests whether these medicines make tumours shrink in participants with lung and breast cancer . (researcherprofiles.org)

Several chemotherapeutic molecules have proven their potential in treatment of breast tumour. (degruyter.com)

These cells support tumour growth and recurrence and are resistant to radiotherapy and chemotherapy. (nih.gov)

Solitary extramedullary plasmacytoma (SEP) describes solid plasma cell tumours of soft-tissue origin as opposed to solitary plasmacytoma of bone. (2011globalhealth.org)

Primary endpoints were change in bone-alkaline phosphatase (ALP) concentration and time to skeletal-related events (SREs). (researchgate.net)
The tumour was seen to focally infiltrate into surrounding skeletal muscle. (biomedcentral.com)

Ewing-like sarcomas of bone and soft tissues: entities, strategies and outcomes. (emsos.org)
Primary leiomyosarcoma of bone (LMSoB) is a rare subtype of bone sarcomas, accounting for less than 0.7% of all malignant bone tumours. (emsos.org)
Bone tumours comprised 5 osteosarcomas, 5 Ewings sarcomas, and 12 chondrosarcomas. (biomedcentral.com)
Bone sarcomas are classified by group (eg, chondrogenic, osteogenic, fibrohistiocytic, Ewing sarcoma) and further subtyped within each group. (medscape.com)

Anatomy4

Diseases14

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes5

Information Science1

Health Care1

Tumor14

Metastasis11

Diagnosis17

Plasmacytoid dendritic cel2

Solid tumours6

Marrow17

Classification15

Lesion4

Suppressor1

Excision4

Abnormal2

Lesions9

Histologically2

Secondary5

Tumors4

Osteosarcoma1

Brown Tumours2

Skin tumours1

Clinical4

Epithelial2

Pathology6

Carcinoma1

Uncommon2

Metastatic1

Metastases8

Resection4

Connective tissue2

Cartilage2

Paediatric1

Chondrosarcoma1

Primary malignant bone1

Aggressive2

Cancers2

Fibroma1

Proximal tibia2

Mesenchymal2

Histological3

Progression2

Acute1

Cancer2

Breast1

Recurrence1

Plasmacytoma of bone1

Skeletal2

Sarcomas4