• Unlike nearly all syngeneic mouse tumors, the JC1-2-shaped tumors resembled 'swollen tumors' because of the abundancy of immune system cells in Naringin (Naringoside) the tumor microenvironment. (mycareerpeer.com)
  • Orthotopic and heterotopic mouse tumor types of JC1-2 cells had been established and even more intense immune system responses had been seen in the microenvironment from the orthotopic model. (mycareerpeer.com)
  • However, the mechanism through which RAD18 influences triple-negative breast cancer (TNBC), especially the interaction between tumor cells and the tumor microenvironment, remains elusive. (nature.com)
  • Tumor microenvironment (TME) remodeling is a critical process in primary tumor progression. (nature.com)
  • Additionally, characterization of the tumor microenvironment such as interactions with immune cells remain largely unknown. (springer.com)
  • Apart from CSCs, there are a myriad of factors and interactions between various cell types and the tumor microenvironment (TME) that ultimately affect CCA progression. (springer.com)
  • LOH is normally connected with tumor suppressor genes (such as for example p53), which inhibit the event of malignant tumors when both alleles can be found. (mycareerpeer.com)
  • Glioma, the vast majority of intracranial malignant tumors, is characterized by rapid proliferation and aggressive invasion [ 1 ]. (jcancer.org)
  • Oral cancer is one of the most prevalent malignant tumors worldwide. (jcancer.org)
  • 1 These tumors are difficult to find because their early symptoms are not obvious, and most of these tumors would have already progressed to the late stage with lymphatic or distal metastasis by the time they are discovered. (dovepress.com)
  • Infiltration versus metastasis is one of the most characteristic biological properties of tumors [ 5 ]. (hindawi.com)
  • Generally, it is believed that there are four main pathways between tumor invasion and metastasis, including local invasion, blood, lymphatic, and seeding metastasis [ 6 ]. (hindawi.com)
  • In addition to these four pathways, tumors can undergo infiltration around nerve fibers and metastasis along nerves, that is, perineural invasion (PNI), which refers to the phenomenon of perineural invasion by tumor cells filling the perineurial space, wrapping around nerves in a continuous concentric sheath-like pattern, infiltration, and metastasis of extension along nerves around nerve fibers or into perineurium within the perineurium [ 7 ]. (hindawi.com)
  • Angiogenesis is essential in the process of carcinogenesis to facilitate tumor progression and metastasis. (spandidos-publications.com)
  • In addition, lung metastasis was observed in nude mice in T-16HBE-C1, 3 and 4 groups.In vitrocell migration assay results indicated that T-16HBE-C2?5 cells showed much lower migration capabilities than 16HBE cells. (eurekamag.com)
  • Here, we determined that upregulation of the oncogenic transcriptional coregulator steroid receptor coactivator 2 (SRC-2), also known as NCOA2, drives glutamine-dependent de novo lipogenesis, which supports tumor cell survival and eventual metastasis. (jci.org)
  • Metabolic profiling of human prostate tumors identified a massive increase in the SRC-2-driven metabolic signature in metastatic tumors compared with that seen in localized tumors, further implicating SRC-2 as a prominent metabolic coordinator of cancer metastasis. (jci.org)
  • C ) H&E-stained sections of mouse lungs from experimental lung metastasis assay. (jci.org)
  • Therefore, inhibiting EGFR alone may not be sufficient for substantial inhibition of all tumor cells, highlighting the need for multipoint intervention. (aacrjournals.org)
  • Inhibition of YAP or TGF-β breaks this loop and suppresses cancer stemness and proliferation In nude mice, RAD18 promoted subcutaneous transplanted tumor growth and M2-type TAM recruitment. (nature.com)
  • However, in recent years, there has been increasing evidence that metformin exerts its anticancer effects through the inhibition of oxidative phosphorylation (OXPHOS) of tumor cell mitochondria, and metabolic pathways based on metformin targeting have only recently become the focus of intensive research. (spandidos-publications.com)
  • Although the mechanism of the effect of the emitted qi still remains unknown, the results of the present research reveals the necessity as well as the possibility of further investigating the inhibition of tumors and its mechanism. (qigonginstitute.org)
  • However, it is believed that direct antiproliferative action against tumor cells, inhibition of virus replication and modulation of the host immune response play important roles in antitumor and antiviral activity. (drugs.com)
  • Our findings demonstrate that PKM2 promotes tumor progression and galectin-9-mediated immunosuppression via NF-κB signaling inhibition in HNSCC, which bridges metabolism and immunosuppression. (researchsquare.com)
  • Silibinin significantly inhibited xenograft tumor growth in nude mice, with no obvious toxicity. (jcancer.org)
  • Importantly, silibinin effectively suppressed xenograft tumor growth in nude mice. (jcancer.org)
  • Because of the different tumorigenicities in nude and C57BL/6 mice, the disease fighting capability might play a significant role in inoculated JC1 tumor progression. (mycareerpeer.com)
  • We used a prototype of an in vivo BT-MRI apparatus to visualise organs and tumors and to analyse tumor progression in nude mouse xenograft models of human testicular germ cell tumor and colon carcinoma. (biomedcentral.com)
  • Monitoring of tumor progression evaluated by pixel extension analyses based on NMR images correlated with increasing tumor volume calculated by calliper measurement. (biomedcentral.com)
  • BT-MRI provides satisfactory image quality to visualize organs and tumors and to monitor tumor progression and structure in mouse models. (biomedcentral.com)
  • Nude mouse xenograft models of different human tumors were used to test the suitability of the new BT-MRI system for visualisation of organs and tumors and for quantification of tumor progression. (biomedcentral.com)
  • Our previous study showed that it plays an essential role in the progression of multiple tumors. (nature.com)
  • Pyruvate kinase M2 (PKM2) is a key rate-limiting enzyme in glycolysis, and which plays a critical role in tumor progression in various malignancies. (researchsquare.com)
  • However, how metabolism reprogramming promotes tumor progression and immune escape remains unclear. (researchsquare.com)
  • However, how PKM2 promotes tumor progression and its mechanism remain obscure. (researchsquare.com)
  • Therapeutic approaches that target the metabolism of tumor cells have been a popular research topic in recent years. (spandidos-publications.com)
  • However, the mitochondrial oxidative phosphorylation (OXPHOS) pathway in tumor cells has also been implicated in lung cancer metabolism. (spandidos-publications.com)
  • Given the vast differences in metabolism between healthy and tumor cells, there is hope that selective targeting of tumor metabolism may be achieved while limiting toxicity to healthy tissue. (spandidos-publications.com)
  • This work reveals the possible relationship between intestinal flora, metabolism and immunity and RA in mice, which will provide new therapeutic strategies for RA. (bvsalud.org)
  • TAMs are the major inflammatory cells in the TME, and are closely related to poor outcomes in several types of tumors [ 11 ]. (nature.com)
  • HU-336 is highly effective against tumor xenografts in nude mice. (wikipedia.org)
  • In the present study, we aimed to further examine the potential of formononetin in controlling angiogenesis and tumor cell invasiveness in human colon cancer cells and tumor xenografts. (spandidos-publications.com)
  • The potential anti-angiogenic effect of formononetin was examined in nude mouse xenografts. (spandidos-publications.com)
  • In recent years, we focused on investigating the anti-carcinogenic properties of total Astragalus saponins (AST) in human colon cancer cells and tumor xenografts. (spandidos-publications.com)
  • Therefore, the density of microvessels in tumor tissues has become an important key to the smooth growth of tumors. (ganoherb.com)
  • In other words, the combination of GLTs and GEF can block more tumor tissues from obtaining nutrients and make tumors more difficult to grow. (ganoherb.com)
  • After injection in mice they displayed rapid, high, and specific localization in the CCK-2/gastrin-R-expressing tissues (stomach and AR4-2J tumor) and were excreted from the body via the kidneys in the form of hydrophilic metabolites. (snmjournals.org)
  • Traditionally, CSCs are identified through a combination of surface markers, however, there is a lack of consensus among the scientific community, especially as these combinations appear to be specific to the corresponding tissues and tumors. (springer.com)
  • The tumor size and the number of proliferating cells were reduced in the tumor tissues obtained from the formononetin-treated group. (spandidos-publications.com)
  • In addition, the researchers also observed in the tumor tissue sections of each group of mice that under the combined action of GLTs and GEF, the secretion of protein (Bax) that promotes cancer cell apoptosis will significantly increase while the secretion of protein (Bcl-2) that inhibits apoptosis of cancer cells will decrease. (ganoherb.com)
  • Finally, the inhibitory effect of the combined chidamide and bortezomib treatment on MGC-803 cells was verified in vivo through tumor formation experiments in nude mice. (dovepress.com)
  • Splenocytes had been isolated from C57BL/6 mice and co-cultured with JC1-2 cells to verify the responsiveness Naringin (Naringoside) from the interferon (IFN)- pathway in the JC1-2 cell range. (mycareerpeer.com)
  • Studies reported that caffeic acid might promote apoptosis in MG-63 osteosarcoma cells, however, the effect of caffeic acid treatment in preventing tumour mass formation has not been well elucidated, especially in MG-63 cells-induced nude mice in vivo . (inabj.org)
  • MG-63 cells were pre-treated with 0, 1, or 10 µg/mL caffeic acid, and 6 hours after pre-treatment, MG-63 cells were injected into subcutaneous space of mice to induce osteosarcoma. (inabj.org)
  • Another model was also created by subcutaneously injecting MG-63 cells to the back of mice, and after 48 days, the visible tumour mass was injected intra-tumour with 0 or 10 µg/mL caffeic acid every 7 days for 6 times. (inabj.org)
  • In pre-treated MG-63 cells-induced mice, volumes of the mass decreased in reverse with the dose of caffeic acid given. (inabj.org)
  • Results of caffeic acid pre-treatment and caffeic acid treatment in tumour mass of mice show that caffeic acid is able to inhibit the MG-63 cells formation. (inabj.org)
  • Poincloux R, Lizarraga F, Chavrier P . Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. (nature.com)
  • Cancer stem cells (CSCs) represent a small subset of the tumor population and reside at the apex of the hierarchy [ 9 ]. (springer.com)
  • Certain metabolic alterations, also referred to as metabolic reprogramming, are commonly observed in tumor cells and are proposed to be hallmarks of cancer ( 8 ). (spandidos-publications.com)
  • In the first experiment, a qigong master treated the poorly differentiated nasopharyngeal squamous cell carcinoma cell line (CNE-2) with his emitted qi, followed by the innoculation of the treated cell (qigong group) and the untreated cells (control group) into 16 female nude mice (NC-Z strain mice). (qigonginstitute.org)
  • The results showed that the tumor formation of the treated cells was inhibited by an impressive rate of 100% (3/3). (qigonginstitute.org)
  • A pathological examination further confirmed that there were no tumo cells in the inoculating site of the qigong group, whereas poorly differentiated squamous cell carcinomas were observed in tumor of the control group. (qigonginstitute.org)
  • Further, nude mice were injected with TCE-transformed cells. (cdc.gov)
  • All the mice injected with transformed cells developed tumors indicating the tumorigenic potential of TCE. (cdc.gov)
  • DNA from transformed cells were subjected to differential PCR to detect changes in gene copy number and gene expression of six protooncogenes (K-ras, c-fos, c-jun, c-myc, c-sis, erb-B2) and two tumor suppressor genes (p53, p16). (cdc.gov)
  • Mice were inoculated with PC-3 prostate cancer cells followed by a 7-week tumor development. (umd.edu)
  • After xenograft, dietary selenium status does not affect levels of CD4 and CD8 T cells in adult nude mice in Experiment 1, while high selenium resulted in significant decrease in CD4 T cells in young nude mice in Experiment 2. (umd.edu)
  • T-16HBE-C1?5 cells can form tumors subcutaneously in nude mice. (eurekamag.com)
  • T-16HBE-C1?5 cells all formed tumors subcutaneously in nude mice. (eurekamag.com)
  • Using a mouse model of ependymoma-a chemoresistant brain tumor-we combined multicell high-throughput screening (HTS), kinome-wide binding assays, and in vivo efficacy studies, to identify potential treatments with predicted toxicity against neural stem cells (NSC). (nih.gov)
  • Nude mice were injected via the tail vein with PC-3 cells stably expressing shNT, sh18, and sh19 ( n = 7), and growth and survival of the cells in mouse lungs were analyzed after 5 weeks. (jci.org)
  • D ) Quantification of Ki67-stained cells (antibody epitope reacts with human Ki67 protein) in mouse lung sections from shNT-, sh18-, and sh19-injected animals. (jci.org)
  • The balance of immune cells in the intestine of RA mice was significantly disrupted, with an overall decrease in immune cells. (bvsalud.org)
  • Here we investigated whether quantification of a xenograft tumor intrinsic fluorescence signal can be used to evaluate tumor growth and response to chemotherapy. (nih.gov)
  • Studies on the anti-tumour, anti-bacterial, and wound-healing properties of dragon's blood. (rain-tree.com)
  • The anti-tumour action of the two antibodies prevents the establishment of DU145 cell tumour in nude mice in vivo. (ias.ac.in)
  • [ 5 ] and 34-36.4% of all primary brain tumors, making meningiomas the most common primary brain tumors. (medscape.com)
  • However, in some cases final necropsy revealed the existence of additional, deeper located tumors that had not been detected in vivo by their mPlum signal. (nih.gov)
  • Consistently, only the weights of the tumors that were detected in vivo based on their mPlum signal correlated with FI. (nih.gov)
  • The effects of the low-dose chidamide and bortezomib combination reduced the growth on gastric cancer in vivo were investigated by using a subcutaneous tumor mouse model. (dovepress.com)
  • Subsequently, we used a model of neuroinvasion in nude mice to assess the effect of NGF in vivo on tumor nerve invasion as well as on nociceptive transmission. (hindawi.com)
  • As nonsulfated gastrin derivatives were shown to be more suitable for tumor targeting by virtue of their CCK-2 receptor selectivity, high affinity, and favorable in vivo profile ( 20 ), Behr et al. (snmjournals.org)
  • The in vivo effects of silibinin were evaluated using a Ca9-22 xenograft mouse model. (jcancer.org)
  • Moreover, in vivo studies confirm that the CTAC@MSNs-HSA are able to induce cancer cell death and efficiently inhibit tumor growth. (rsc.org)
  • In vivo, Interferon alfa-2a, recombinant has been shown to inhibit the growth of several human tumors growing in immunocompromised (nude) mice. (drugs.com)
  • For in-vivo evaluation, simultaneous triple-isotope and multi-animal studies were performed on mice. (unav.edu)
  • Applying subcutaneous tumor models in different experimental designs, specific correlations between measured total fluorescence intensity (FI) and the tumor volume (V) could be established. (nih.gov)
  • Tumour proliferation and hypoxic status were evaluated using F-18-fluoro-3 '-deoxy-3 '-L-fluorothymidine (FLT)- and F-18-fluoromisonidazole (FMISO)-positron emission tomography (PET) at baseline, and during C1 and C5. (unav.edu)
  • These findings suggest that formononetin inhibits angiogenesis and tumor cell invasion, and thus support its use in the treatment of advanced and metastatic colon cancers. (spandidos-publications.com)
  • The vascular endothelial growth factor (VEGF) is a well characterized angiogenic factor known to stimulate angiogenesis within a tumor ( 1 ). (spandidos-publications.com)
  • Simple Summary New blood vessel formation (angiogenesis) has a crucial role in tumour growth and spread. (unav.edu)
  • GLTs and GEF can inhibit the growth of lung adenocarcinoma tumors, but the combination of the two has a better effect (Figure 1~3). (ganoherb.com)
  • developed [ 111 In-DTPA 0 ]minigastrin showing high uptake in stomach and tumor lesions in metastatic MTC patients ( 20 ). (snmjournals.org)
  • In 1938, Cushing and Eisenhardt first used the term "meningioma" to describe these lesions and introduced it as a separate category of extraparenchymal tumors. (medscape.com)
  • This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments. (cancerindex.org)
  • Sphenoid wing meningiomas are categorized as lateral, middle, or medial (clinoidal), depending on the origin of the tumor along the sphenoid ridge. (medscape.com)
  • Rutin exerts antitumor effects on nude mice bearing SW480 tumor. (rain-tree.com)
  • Because of its species-restricted activity, it has not been possible to demonstrate antitumor activity in immunologically intact syngeneic tumor model systems, where effects on the host immune system would be observable. (drugs.com)
  • However, such antitumor activity has been repeatedly demonstrated with, for example, mouse interferon-alfa in transplantable mouse tumor systems. (drugs.com)
  • Chemical substance induction was utilized to determine the tumorigenicity-enhanced cell range, JC1-2, that may type syngeneic tumors in immunocompetent C57BL/6 mice. (mycareerpeer.com)
  • These qualities could be confirmed for [ 99m Tc]Demogastrin 2, which provided excellent delineation of tumor deposits in a first patient with metastatic medullary thyroid cancer. (snmjournals.org)
  • SRC-2 was highly elevated in a variety of tumors, especially in prostate cancer, in which SRC-2 was amplified and overexpressed in 37% of the metastatic tumors evaluated. (jci.org)
  • The advent of radiolabeled somatostatin analogs in the targeted imaging and radionuclide therapy of tumors overexpressing somatostatin receptors has paved the way for other radiopeptides to target alternative cancer-associated peptide receptor systems ( 1 - 4 ). (snmjournals.org)
  • A continuous monitoring of the whole tumor burden of individuals in orthotopic tumor models is a desirable aim and requires non-invasive imaging methods. (nih.gov)
  • Furthermore, more intense immune system responses had been seen in the orthotopic mouse model than in the heterotopic model. (mycareerpeer.com)
  • In addition, the cytokine byproduct TGF-β activates macrophages to have an M2-like tumor-associated macrophage (TAM) phenotype. (nature.com)
  • We noted direct coculturing increased stemness among CSC populations and induced both M1 (CD80 and HLA-DR) and M2 (CD163) tumor associated macrophage polarization. (springer.com)
  • These studies suggest that there is a bi-directional crosstalk between macrophages and CSCs that promotes stemness renewal and tumor associated macrophage polarization. (springer.com)
  • Stably fluorescence protein (FP) expressing cell clones of colorectal carcinoma and germ cell tumor lines were generated by lentiviral transduction using the FPs eGFP, dsRed2, TurboFP635, and mPlum. (nih.gov)
  • S. Choofong, P. Cloutier, L. Sanche, J. R. Wagner "Increased radio-sensitivity of colorectal tumor with intra-tumoral injection of low dose of gold nanoparticles. (usherbrooke.ca)
  • To observe the effects of Asini Corii Colla, turtle carapace glue, and other drugs on the intestinal flora of nude mice with uterine fibroids model, so as to provide evidence for the clinical application of drugs. (hindawi.com)
  • the decrease in the relative abundance of Firmicutes and the increase in the relative abundance of Bacteroidetes were important structural changes of intestinal flora in nude mice at 4 weeks after administration. (hindawi.com)
  • Therefore, on the basis of previous experiments, this study conducted biodiversity sequencing through 16SrRNA to observe the structural changes of intestinal flora of the nude mice with uterine fibroids model under the action of donkey-hide gelatin, turtle shell glue, and other traditional Chinese medicines, providing strong evidence for traditional Chinese medicine to regulate the intestinal microecology of nude mice with uterine fibroids. (hindawi.com)
  • Moreover, we systematically explored how the imbalance of intestinal flora changed the intestinal immune status through its metabolites in RA mice. (bvsalud.org)
  • Our results showed that the intestinal flora of RA mice changed significantly, and the bacteria producing short-chain fatty acids (SCFAs), indole classes and secondary bile acids were significantly reduced. (bvsalud.org)
  • Stylli SS, Kaye AH, Lock P . Invadopodia: at the cutting edge of tumour invasion. (nature.com)
  • Reciprocally, TGF-β from TAMs activated RAD18 in TNBC to enhance tumor stemness, forming a positive feedback loop. (nature.com)
  • A number of therapeutic options are available for patients with prostate carcinoma till the time that the tumour is hormone dependent. (ias.ac.in)
  • In conclusion, as long as tumors are visualized by their fluorescence signal the FI can be used to evaluate tumor burden. (nih.gov)
  • The researchers first implanted human alveolar adenocarcinoma cell lines (A549 cell lines) under the skin of mice with compromised immune systems. (ganoherb.com)
  • Following the double-blind method, we carried out two experiments by using cell cultures and nude mice. (qigonginstitute.org)
  • Taken together, there is an opposing role of excessive selenium on tumor xenograft development in adult and young nude mice carrying differential T cell profiles. (umd.edu)
  • Cell adhesion molecule-1 (CADM1) is a member of the immunoglobulin superfamily that functions as a tumor suppressor of lung tumors. (cancerindex.org)
  • Histopathological changes in the tumors indicated nests growth, high nuclear-cytoplasmic ratios, coarse and clumped chromatin, numerous and distinctly atypical mitoses, cell necrosis and surrounding normal adipose, muscle and connective tissue immersed. (eurekamag.com)
  • The product of a hybrid cell clone, P 3 W 80 , obtained as ascites fluid from mouse peritoneal cavity had high titres of anti-human chorionic gonadotropin antibodies e.g. 30 to 40% binding of 125 I-human chorionic gonadotropin at 10 7 dilution in a radioimmunoassay. (ias.ac.in)
  • In a model of visceral growing mPlum tumors, measurements of FI could be used to follow growth and response to chemotherapy. (nih.gov)
  • The implications of this finding overshadowed the importance of mitochondria for tumor growth for a long time. (spandidos-publications.com)
  • It has also been shown that metformin and phenformin inhibit tumor growth by disrupting mitochondrial complex. (rsc.org)
  • In this study, we used a combination of imaging techniques and VEGF marker levels to show that bevacizumab caused structural and functional changes in the blood vessels of breast tumours and substantially slowed tumour growth. (unav.edu)
  • Two different growing patterns of sphenoid wing meningioma have been described: meningioma en masse, forming a nodular space-occupying lesion, and meningioma en plaque, which is flat and demonstrates a carpet-like growth pattern. (medscape.com)
  • The aim of this study was to evaluate 3 new 99m Tc-labeled minigastrin analogs modified with open chain tetraamines at the N-terminus for their suitability in the CCK-2/gastrin-R-targeted imaging of tumors (CCK-2/gastrin-R = cholecystokinin subtype 2/gastrin receptor). (snmjournals.org)
  • 0.001), independent of tumour subtype. (unav.edu)
  • The specific pathogenesis of uterine fibroids has not been fully defined, but it is generally believed that high levels of estrogen and progesterone can promote the formation and development of uterine fibroids, that is, uterine fibroids are considered sex hormone-dependent tumors [ 2 ]. (hindawi.com)
  • The promising characteristics of [ 99m Tc]Demogastrin 1-3 both in vitro and in animal models illustrate their suitability for CCK-2/gastrin-R-targeted tumor imaging. (snmjournals.org)
  • In view of the above, several investigators have been involved in the development of radiolabeled gastrin/CCK analogs for targeted diagnostic imaging and radionuclide therapy of CCK-2/gastrin-R-expressing tumors. (snmjournals.org)
  • Photoacoustic (PA) imaging has shown tremendous promise for imaging tumor vasculature and its function at deeper penetration depths without the use of exogenous contrast agents. (mdpi.com)
  • In this study, we evaluated the capability of a Light-Emitting Diode (LED)-based PA and ultrasound (US) imaging system for monitoring heterogeneous microvasculature in tumors (up to 10 mm in depth) and quantitatively compared the PA images with gold standard histology images. (mdpi.com)
  • The performance of the SPECT was evaluated for two collimators dedicated for mouse (UHS-M) and rat imaging (UHR-RM) in terms of sensitivity, energy resolution, uniformity and spatial resolution. (unav.edu)
  • In mice, simultaneous multi-isotope imaging provided the separate distribution of 3 tracers and image quality of the multi-mouse bone scan was adequate. (unav.edu)
  • However, there are no validated methods for predicting which patients will respond to bevacizumab, although some have investigated whether a response can be predicted by using scanning (imaging) techniques that study tumour blood vessels or by using the levels of VEGF markers before treatment. (unav.edu)
  • In positron emission tomography (PET)/CT, the high rate of glycolysis in NSCLC is reflected by the high uptake of 18F-fluorodeoxyglucose at the corresponding tumor sites ( 12 ). (spandidos-publications.com)
  • In addition, mitochondria have also been proved to be essential for tumor generation and development. (rsc.org)
  • Both LCRF-0004 and BMS-777607 demonstrated significant anti-tumor efficacy in vitro , however BMS-777607 was far superior to LCRF-0004. (frontiersin.org)
  • As a total result, a trusted mouse model can be urgently necessary for tumor Naringin (Naringoside) immunology research (14). (mycareerpeer.com)
  • Two beats one: osteosarcoma therapy with light-activated and chemo-releasing keratin nanoformulation in a preclinical mouse model. (inabj.org)
  • Then, the model nude mice were fed ejiao, turtle carapace glue, and other corresponding drugs. (hindawi.com)
  • Before administration, 2 weeks after administration, and 4 weeks after administration, the feces of the model nude mice were taken respectively, subpacked into labeled cryotubes, and stored at −80°C. All samples were sent for gene sequencing after completion. (hindawi.com)
  • Sphenoid wing meningiomas also are known as "orbitosphenoid meningiomas," "meningiomas en plaque of the sphenoid wing," and "sphenoid wing meningiomas with osseous involvement. (medscape.com)
  • The orbital involvement of the tumor causes significant proptosis of the affected eye. (medscape.com)
  • 2 Thus, simple surgical treatment cannot aid in full eradication of these tumors. (dovepress.com)
  • 10-12 Noticeably, cationic surfactant is more extensively used in tumor treatment than other types of surfactants, such as anionic and nonionic surfactant. (rsc.org)
  • Histopathology of the tumor may determine the postoperative treatment course for patients. (medscape.com)
  • Tumors need to create new vessels in order to continue to grow. (ganoherb.com)
  • they fall into 1 of 3 categories, according to the presence of an interfacing arachnoidal membrane between the tumor and the cerebral vessels. (medscape.com)
  • Figure 4 (A) shows the distribution of microvessels in the tumor tissue slices of each group. (ganoherb.com)
  • Tissue distribution of the peptides was compared in healthy mice and athymic mice bearing AR4-2J tumors. (snmjournals.org)
  • Uterine fibroids are benign tumors of the uterine smooth muscle tissue, which occur in women of childbearing age at 30-50 years. (hindawi.com)
  • Photocarcinogenesis in hairless mice induced tumors harbors more UVA than UVB fingerprint by ultraviolet A tanning devices with or without mutations: A role for UVA in human skin car- subsequent solar-simulated ultraviolet irradia- cinogenesis. (who.int)