Genes, Tumor SuppressorCell CycleTumor Suppressor ProteinsCell Cycle ProteinsTumor Suppressor Protein p53Cell Line, TumorG1 PhaseCheckpoint Kinase 2Disease ProgressionS PhaseMutationGene Expression Regulation, NeoplasticGenes, p53MitosisProtein-Serine-Threonine KinasesCell DivisionCell Cycle CheckpointsRetinoblastoma ProteinCell ProliferationLoss of HeterozygosityDNA DamageG2 PhaseApoptosisMolecular Sequence DataDNA-Binding ProteinsDNA MethylationCyclinsNuclear ProteinsSignal TransductionCyclin-Dependent Kinase Inhibitor p21Tumor Cells, CulturedBase SequencePhosphorylationGene SilencingCyclin-Dependent Kinase Inhibitor p16Genes, cdcGenes, SuppressorTranscription FactorsPromoter Regions, GeneticGene DeletionCell LineCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p27Tumor Suppressor Protein p14ARFVon Hippel-Lindau Tumor Suppressor ProteinDNA, NeoplasmRNA, MessengerCyclin-Dependent KinasesPTEN PhosphohydrolaseDown-RegulationM Phase Cell Cycle CheckpointsTransfectionCyclin D1NeoplasmsNeoplasm ProteinsProtein KinasesBlotting, WesternAmino Acid SequenceReverse Transcriptase Polymerase Chain ReactionProto-Oncogene ProteinsCyclin-Dependent Kinase 2HeLa CellsDNA ReplicationGenes, RetinoblastomaTranscription, GeneticG2 Phase Cell Cycle CheckpointsRNA, Small InterferingProtein BindingCells, CulturedCDC2 Protein KinaseRepressor ProteinsE2F Transcription FactorsCyclin EFlow CytometryPolymerase Chain ReactionBreast NeoplasmsCarrier ProteinsE2F1 Transcription FactorGene Expression RegulationImmunohistochemistryModels, BiologicalSpindle ApparatusProteinsCyclin-Dependent Kinase 4RNA InterferenceCyclin BTumor Markers, BiologicalCell NucleusChromosomes, Human, Pair 3Cell SurvivalTime FactorsPhenotypecdc25 PhosphatasesFibroblastsCyclin ASaccharomyces cerevisiae ProteinsMice, NudeChromosome MappingUbiquitin-Protein LigasesDNA Primers