Tumor spinal neoplasms. Medical search. Frequent questions

Hemangiomas (benign tumors of the blood vessels) are usually discovered incidentally and usually do not produce symptoms. (medscape.com)
Outcomes depend on a number of factors including whether the tumor is benign or malignant, primary or metastatic, and location of the tumor. (wikipedia.org)
The diagnosis is challenging, primarily because symptoms often mimic more common and benign degenerative spinal diseases. (wikipedia.org)
The following chapters are dedicated to new insights in the medical treatment of bone tumors, an overview on the mechanism of malignant transformation of benign bone tumors, the modern management of pain in bone metastases, and the modern therapeutics of bone tumors in prostate cancer patients. (novapublishers.com)
Most intradural tumors are benign and are usually meningiomas, schwannomas, neurofibromas, or myxopapillary ependymomas. (msdmanuals.com)
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. (embl.de)
Findings from a 51-year-old immunocompetent woman with a benign neoplasm and Cryptosporidium baileyi pulmonary infection, Poland, 2015. (cdc.gov)
We report one of the largest benign sacral schwannoma originating inside the spinal canal with pelvic extension to be resected without complications. (nih.gov)
They can occur in any tissue or organ and can range from benign, non-cancerous tumors to invasive, life-threatening tumors. (openaccesspub.org)
The diagnosis of primary spinal cord tumors is very difficult, mainly due to its symptoms, which tend to be wrongly attributed to more common and benign degenerative spinal diseases. (gloucestershirespinalsurgery.com)
The diagnosis of primary spinal cord tumors is difficult, mainly due to their symptoms, which in early stages mimic more common and benign degenerative spinal diseases. (gloucestershirespinalsurgery.com)
This expansion gives rise to a small benign colon tumor (called a polyp or adenoma). (hopkinsmedicine.org)
Mutations in four or five such genes are required for a malignant tumor to form, while fewer mutations suffice for benign tumorigenesis. (hopkinsmedicine.org)

The symptoms of spinal tumors are often non-specific, resulting in a delay in diagnosis. (wikipedia.org)
The first step towards diagnosis and therapy is recognizing that the patient has some sort of spinal cord pathology. (emcrit.org)
It is a clinical diagnosis confirmed radiologically with evidence of compression of the cauda equina, or the collection of nerves at the end most part of the spinal cord. (joionline.net)
The differential diagnosis of low back pain radiating to the leg should include tumor when there is a history of cancer, pain not relieved by conservative treatment nor by lying down, pain is increased at night, pain accompanied by weight loss, and when physical examination demonstrates injury to more than 1 nerve root. (tau.ac.il)
It also covers advances in immunotherapy, genetics, and genomics of neoplasms, novel biomarkers, and advances in imaging in neoplasm diagnosis and prognosis. (openaccesspub.org)
The goals of surgical treatment for spinal tumors can include histologic diagnosis, tumor local control or oncological cure, pain relief, spinal cord decompression and restoration of neurological function, restoration of spine stability, and deformity rectification. (gloucestershirespinalsurgery.com)
In addition, we review the literature and our experience in using an anatomic classification system to narrow the differential diagnosis for patients with spine tumors. (johnshopkins.edu)
Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. (bvsalud.org)

Nerves to the cervical cord are located closest to the middle of the cord, whereas nerves to the sacrum are located farthest towards the edges of the spinal cord. (emcrit.org)
Due to their resistance to oncologic treatment and a low tendency to metastasize, the management of primary tumors of the sacrum is resection with wide margins. (aott.org.tr)

Indications of embolization in bone and soft tissue tumors. (ajnr.org)

Metastatic lesions are responsible for about 85% of neoplastic spinal cord compression cases, with the other 15% due to primary neoplastic lesions of the spine. (medscape.com)
Metastatic lesions that involve the spinal cord affect about 5-10% of patients with cancer. (medscape.com)
Endovascular Treatment of Spine and Spinal Cord Lesions. (ajnr.org)
Metastatic lesions are featured in this discussion since they cause 85% of the cases of neoplastic spinal cord compression. (medscape.com)
[ 3 ] Approximately 15% of all primary CNS lesions arise from the spinal cord, with an estimated incidence rate of 0.5-2.5 cases per 100,000 population. (medscape.com)
The Epley maneuver and the Semont maneuver have not been demonstrated to be effective in persons with disorders of the central nervous system such as temporal lobe epilepsy, multiple sclerosis, cerebrovascular disease, vertiginous migraine, cerebellopontine angle tumors, and primary or metastatic cerebellar lesions, based on neurological examination, magnetic resonance imaging, or history. (kipdf.com)
Extranodal Rosai-Dorfman disease with multiple spinal lesions: Arare presentation. (jbstjournal.com)
Three independent factors were found to be associated with increased risk for neurologic deficit: 1) bilateral tumors at the same level in the cervical region that approximated each other, 2) paraspinal tumors at the lumbar region, and 3) intradural lesions. (ajnr.org)
Three months later, a cervical MRI showed progression of the tumor, along with new lesions in the thoracic/lumbar spine plus intracranial punctate nodular tumors. (surgicalneurologyint.com)
She underwent disease reevaluation 4 weeks after the completion of radiation, which showed improvement in the spinal tumor and no new metastatic lesions. (surgicalneurologyint.com)
5. Spinal cord compression, brain metastases or leptomeningeal metastases unless these lesions are definitively treated (eg. (who.int)

Most primary intramedullary spinal cord tumors are astrocytomas or ependymomas . (medscape.com)
The most common type of intradural-intramedullary tumors are ependymomas and astrocytomas. (wikipedia.org)
Intradural-intramedullary tumors are located within the spinal cord itself, with the most common being ependymomas, astrocytomas, and hemangioblastomas. (wikipedia.org)
The most common intramedullary tumors are gliomas, particularly ependymomas and low-grade astrocytomas. (msdmanuals.com)
Intramedullary tumors, or gliomas (astrocytomas or ependymomas), are comparatively rare, accounting for only about 10% of tumors. (health-care-clinic.org)

Leptomeningeal metastasis presents as multifocal neurological deficits referable to the spinal cord. (medscape.com)
Symptoms can include progressive back pain and neurologic deficits referable to the spinal cord or spinal nerve roots. (msdmanuals.com)

Primary spinal cord tumors arise from the different elements of the central nervous system (CNS), including neurons, supporting glial cells, and meninges. (medscape.com)
Primary spinal tumors are associated with a few genetic syndromes. (wikipedia.org)
Primary spinal neoplasms originate in the meningeal coverings, the parenchyma of the cord or its roots, the intraspinal vasculature, or the vertebrae. (health-care-clinic.org)
Primary spinal cord tumors may be extramedullary (occurring outside the spinal cord) or intramedullary (occurring within the cord itself). (health-care-clinic.org)
Extramedullary tumors may be intradural (meningiomas and schwannomas), which account for 60% of all primary spinal cord neoplasms, or extradural (metastatic tumors from breasts, lungs, prostate, leukemia, or lymphomas), which account for 25% of these neoplasms. (health-care-clinic.org)
Primary spinal cord tumors arise from the different elements of the CNS, including neurons, supporting glial cells, and meninges. (medscape.com)
Most primary spinal cord cancers do not disseminate widely through the CNS or body. (medscape.com)
Although primary spinal cord tumors (PSCTs) comprise a minority of primary central nervous system tumors, they often impose a great deal of morbidity on their victims. (ac.ir)
Primary spinal AT/RT in an adult is rare. (surgicalneurologyint.com)
Primary spinal AT/RT in the adult patient is rare. (surgicalneurologyint.com)
5 9 ] Primary spinal AT/RT, especially within an adult patient, is rare. (surgicalneurologyint.com)

Infrequently, tumors may induce cavitation within the spinal cord. (medscape.com)
Less frequently, tumors may induce cyst formation or cavitation within the spinal cord. (medscape.com)

Integration of Radiomics and Tumor Biomarkers in Interpretable Machine Learning Models. (cdc.gov)

Most extradural tumors are metastatic. (msdmanuals.com)

Embolization of spinal metastases reduces perioperative blood loss. (ajnr.org)
1) Background: Surgery for spinal metastases has gained a decisive role in modern oncological treatment. (scite.ai)
Preliminary clinical experience with CFR-PEEK implants for spinal metastases exists. (scite.ai)
2) Methods: We retrospectively analyzed prospectively the collected data of consecutive patients being operated on from 1 August 2015 to 31 October 2021 using a CFR-PEEK pedicle screw system for posterior stabilization because of spinal metastases or primary bone tumors of the spine. (scite.ai)
Spinal metastases may result in focal findings at a spinal cord level or nerve root pain. (medscape.com)

Neoplastic disease that involves the spine and results in spinal cord or cauda equina compression may have devastating neurologic and functional consequences. (medscape.com)

As the director of Spine Surgery for the Department of Neurosurgery at the University of Maryland, I see a large volume of patients with spinal deformity, degenerative disease, spinal oncology and spine trauma. (umaryland.edu)

Back pain may prompt a bone scan to confirm or exclude spinal metastasis. (wikipedia.org)
The majority of extradural tumors are due to metastasis, most commonly from breast, prostate, lung, and kidney cancer. (wikipedia.org)
Journal of Neoplasms focuses on both experimental and clinical studies related to neoplasms, such as cancer and tumor biology, carcinogenesis, and metastasis. (openaccesspub.org)
We seek to provide comprehensive data, analyses, and evidence-based research including tumorigenesis and metastasis, immunology and immunotherapy, stem cell transplantation, radiotherapy and oncological drug therapy, artificial intelligence and big data in neoplasms, and much more. (openaccesspub.org)
Dissemination of medulloblastoma within cerebrospinal fluid (CSF) pathways is a defining pathobiologic characteristic of this tumor, and about 30% of patients will have CSF metastasis at presentation. (medscape.com)

Ependymal tumors are pathologically defined intrinsic neoplasms originating in the intracranial compartments or the spinal cord that affect both children and adults. (nih.gov)
Additionally, RELA fusions, mostly presented in pediatric grade III intracranial ependymomas, indicated decreased survival times of patients, and closely related to the patients' age, tumor grade, cellularity, cellular atypia, necrosis and Ki67 index in the intracranial ependymal tumors, whereas reduction of H3K27me3 predicted the worse prognosis in ependymal tumors. (nih.gov)
A spinal neoplasm is anyone of many tumor types that are similar to intracranial tumors and involve the spinal cord or its roots. (health-care-clinic.org)
Spinal cord tumors are rare compared with intracranial tumors (ratio of 1:4). (health-care-clinic.org)
The laboratory has advanced the understanding of gene therapy, angiogenesis, intracranial implantation of biodegradable polymers to treat malignant glioma, tumor genetics and proteomics, microchip drug delivery and drug resistance studies. (hopkinsmedicine.org)

With modern surgical advances, radical resection of pediatric intramedullary spinal cord tumors (IMSCTs) can be expected to preserve long-term neurological function. (johnshopkins.edu)

Multiple spinal levels are affected in about 30% of patients. (medscape.com)
Spinal cord compression is commonly found in patients with metastatic malignancy. (wikipedia.org)
Back pain is a primary symptom of spinal cord compression in patients with known malignancy. (wikipedia.org)
Spinal cord lymphomas are commonly seen in patients with suppressed immune systems. (wikipedia.org)
Histological and molecular features facilitate tumor grading and prognostic predictions for ependymal tumors in Chinese patients. (nih.gov)
In this podcast, Global Spine Journal 's Editor-In-Chief, Jeffrey C. Wang, MD, interviews Daniel Sciubba on his article, Surgical Outcomes in Patients with High Spinal Instability Neoplasm Score Secondary to Spinal Giant Cell Tumors . (libsyn.com)
The study was carried out to exhaust the scientific literature regarding surgery associated with radiotherapy in patients suffering from metastatic spinal cord compression and to assist in the decision of oncology physicians and professionals in choosing the best treatment for the patient. (bvsalud.org)
Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
Occasionally, an extramedullary neoplasm composed from myelocytic precursor cells occurs in patients without evidence of leukemia. (nel.edu)
We present two male patients (ages 19 years) with chondrosarcoma and a giant cell tumor, respectively. (aott.org.tr)
We strive to provide a platform for researchers to share quality research findings and to help improve the care of patients with neoplasms. (openaccesspub.org)
Rapid identification and intervention of malignant spinal tumors, often causing spinal cord compression, is key to maintaining quality of life in patients. (gloucestershirespinalsurgery.com)
Radiotherapy may be administered to patients with malignant tumors. (gloucestershirespinalsurgery.com)
Some suggest that direct decompressive surgery combined with postoperative radiotherapy, provide better outcomes than treatment with radiotherapy alone for patients with spinal cord compression due to metastatic cancer. (gloucestershirespinalsurgery.com)
Dr. Brem and his colleagues have designed and led many multi-institutional clinical trials to improve and expand the range of therapeutic options for patients with brain tumors . (hopkinsmedicine.org)
The aim of this monocentric study is to report on the safety and efficacy of CFR-PEEK pedicle screw systems for spinal neoplasms in a large cohort of consecutive patients. (scite.ai)
The aim of this study was to characterize the radiologic presentation of patients with neurofibromatosis type 1 with widespread spinal disease and to correlate it to clinical presentation and outcome. (ajnr.org)
We conducted a historical cohort study of adult patients with neurofibromatosis type 1 with spinal involvement. (ajnr.org)
Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm of the central nervous system that generally arises intracranially in patients under 2 years of age. (surgicalneurologyint.com)
CNSide can detect and quantify tumor cells in the CSF from patients with Breast Cancer or NSCLC having a suspicious or confirmed LM. (stanford.edu)
We are studying components of blood, tumor tissue, normal tissue, and other fluids, such as urine, cerebrospinal fluid, abdominal or chest fluid in patients with cancer. (stanford.edu)
Predicting the survival of patients with pancreatic neuroendocrine neoplasms using deep learning: A study based on Surveillance, Epidemiology, and End Results database. (cdc.gov)

Metastatic spinal cord compression is due to invading lesion(s) in the epidural space, between the vertebral bones and the dura of the thecal sac, compressing the thecal sac, spinal cord, or cauda equina. (medscape.com)
Evaluating for a sensory level using a pin to detect pain sensation is more sensitive to detect a spinal level originating from a lesion in the spinothalamic tract. (emcrit.org)
Motor weakness may be used to evaluate the level of a spinal lesion that involves the corticospinal tract. (emcrit.org)
Thus, a central spinal cord lesion may cause neurologic deficits in a descending order. (emcrit.org)
In addition to confirming the spinal injury, a solitary pulmonary nodule (SPN), 1.3-1.8 cm, in the third segment of the right lung upper lobe was detected by chest radiography and computed tomography ( Figure , panels A, B). The lesion was of high density and had well-defined borders. (cdc.gov)
An X-ray and magnetic resonance imaging undertaken on 31 Month9 identified an L2 lytic lesion, as well as significant spinal cord compression. (hdc.org.nz)
In this review, we describe the MRI appearance of extradural, intradural-extramedullary, and intradural-intramedullary tumors as well as the image interpretation techniques that permit identification of the compartment in which a lesion is located. (johnshopkins.edu)

Journal of Neoplasms (JN) is a peer-reviewed, open access journal that publishes high-quality, scholarly articles in the fields of neoplasms and oncology, with a focus on the biology, development, and treatment of cancer. (openaccesspub.org)
Artificial Intelligence and Predictive Modeling in Spinal Oncology: A Narrative Review. (cdc.gov)
3. Histologically confirmed HR+/ HER2- breast cancer determined from the most recent tumour sample (primary or metastatic) per the American Society of Clinical Oncology and College of American Pathologists guideline. (who.int)

The treatment of choice in case of favorable tumor location (without hypothalamic involvement) is complete resection. (bvsalud.org)

The most common type of intradural-extramedullary tumors are meningiomas and nerve-sheath tumors. (wikipedia.org)
Intradural-extramedullary tumors are located within the dura but outside of the spinal cord parenchyma, with the most common being meningiomas and nerve sheath tumors (e.g. schwannomas, neurofibromas). (wikipedia.org)
S pinal meningiomas are encountered mostly in the thoracic region in middle-aged women, 1, 11 but occur elsewhere along the spinal canal. (thejns.org)

Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm that constitutes approximately 6% of pediatric central nervous system (CNS) tumors. (surgicalneurologyint.com)

Common primary cancers in metastatic spinal tumors includes breast, prostate, lung, and kidney cancer. (wikipedia.org)
Bone tumors are very rare, accounting for less than 0.2% of all cancers. (novapublishers.com)
Additionally, cancers that metastasize to the vertebrae or surrounding tissues frequently cause spinal cord compression. (medscape.com)
Both tumors are difficult to treat, and new therapies are urgently needed for these cancers. (hopkinsmedicine.org)

Overview of Spinal Cord Disorders Spinal cord disorders can cause permanent severe neurologic disability. (msdmanuals.com)
central nervous system disorders will have an effect on either brain or spinal cord that conclusion in psychiatric disorders or neurologic disorders. (crgconferences.com)
Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from secondary conditions, which result in extrinsic compression of the spinal cord. (bvsalud.org)

Intradural-intramedullary tumors are located within the dura and spinal cord parenchyma, while intradural-extramedullary tumors are located within the dura but outside the spinal cord parenchyma. (wikipedia.org)
Intramedullary tumors infiltrate the parenchyma and expand rather than displace the spinal cord. (msdmanuals.com)
intramedullary tumors, by destroying the parenchyma and compressing adjacent areas. (health-care-clinic.org)
Because intramedullary tumors may extend over several spinal cord segments, their symptoms are more variable than those of extramedullary tumors. (health-care-clinic.org)

Other common symptoms of spinal cord compression include muscle weakness, sensory loss, numbness in hands and legs, and rapid onset paralysis. (wikipedia.org)

Metastatic spinal cord compression usually follows arterial hematogenous dissemination of malignant cells to the vertebral bodies, with subsequent expansion into the epidural space. (medscape.com)
Spread into the epidural space may also occur by means of tumor extension through the intervertebral foramina (as is common with lymphoma) or hematogenous spread to the vertebral bodies by way of the Batson venous plexus (particularly with prostate cancer). (medscape.com)
Principles of treating intramedullary cancer are similar to those for epidural spinal cord compression. (medscape.com)
Spread into the epidural space may occur by means of tumor extension through the intervertebral foramina or hematogenous spread by way of the Batson venous plexus. (medscape.com)
Metastatic tumors that cause epidural cord compression and dysfunction are the most common causes of oncologic CNS injury. (medscape.com)

This comprehensive book is the result of the contribution of different internationally renowned expert teams in the management of bone tumors and particularly spinal neoplasms. (novapublishers.com)
Chapter 6: Aminobisphosphonates and Nano-Technologically Modified Aminobisphosphonates: A New Dawn in the Treatment of Bone and Extra-Bone Tumors? (novapublishers.com)

In a patient with metastatic carcinoma or lymphoma who suddenly experiences complete transverse myelitis with spinal shock, functional improvement is unlikely, even with treatment, and his outlook is ominous. (health-care-clinic.org)

Neoplastic disease can cause neurologic symptoms by compression of the thecal sac, spinal cord, or cauda equina, as well as compression of the attendant vascular supply, which results in cord edema and ischemia. (medscape.com)
If the tumor is at the level of the cauda equina, muscle flaccidity, muscle wasting, weakness, and progressive diminution in tendon reflexes are characteristic. (health-care-clinic.org)
Cauda equina tumors cause bladder and bowel incontinence from flaccid paralysis. (health-care-clinic.org)

The first five chapters deal with spinal tumors, either primary or metastatic, giving the reader a clear clinical review of the disease and its pathophysiology, as well as therapeutic options. (novapublishers.com)
We analyzed the demographic/clinical features of all primary intraspinal tumors (with a specific focus on primary intradural spinal cord tumors) identified between 1992 and 2004 in three of the major related hospitals in Isfahan, Iran. (ac.ir)
Tumors of the spinal cord or near the sciatic or femoral plexus can cause neural compression and clinical signs similar to those of disc herniation. (tau.ac.il)
JN is pleased to publish research that covers topics related to neoplasms, ranging from epidemiology to pathology, carcinogenesis, etiopathogenesis, and clinical management. (openaccesspub.org)
Our lab is currently working on understanding the extreme responders and extreme clinical phenotypes of brain and spinal cord tumors to identify factors that may modulate responses to therapy. (hopkinsmedicine.org)
[ 1 ] These tumors display considerable clinical and biologic heterogeneity, and they have been further defined molecularly and histologically. (medscape.com)

Both intradural and extradural tumors exert their effects by compressing the spinal cord and its roots, rather than by invading the parenchyma. (msdmanuals.com)

Rapid identification and intervention of metastatic spinal cord compression is necessary to preserve neurologic function. (wikipedia.org)
Neurologic deficits referable to the affected level of the spinal cord may develop. (msdmanuals.com)
In this series, neurologic deficit is correlated with tumor burden and subtype. (ajnr.org)

Note that the spinal cord level doesn't line up precisely with the corresponding vertebrae, especially caudal to the thoracic spine. (emcrit.org)

The neurosurgery team assesses and decide if surgery is needed, for neoplasms originating in the brain / spinal cord. (albertahealthservices.ca)

Evidence of spinal compromise may include lower extremity weakness, paresthesias, reflex asymmetry, and spinal pain. (medscape.com)

Metastatic extradural tumors can be controlled with radiation, analgesics and, in the case of hormone-mediated tumors (breast and prostate), appropriate hormone therapy. (health-care-clinic.org)
It is not uncommon for spinal tumors to develop out of a tumor from the individual's breast, lung, kidney, prostate, or another area of the body that has spread out . (sciatica.clinic)

Intradural tumors are located inside the dura mater lining and are further subdivided into intramedullary and extramedullary tumors. (wikipedia.org)
There are many genetic factors associated with intradural tumors, most commonly neurofibromatosis 1 (NF1), neurofibromatosis 2 (NF2), and Von-Hippel Lindau (VHL) syndrome. (wikipedia.org)
citation needed] Intradural tumors are located within the dura mater. (wikipedia.org)

These are further broken down into intramedullary and extramedullary tumors. (wikipedia.org)
Intradural extramedullary tumors may be painful when the nerve roots are compressed but can develop painlessly if the spinal cord is directly compressed without involving the root. (msdmanuals.com)

Spinal nerve compression and weakening of the vertebral structure cause the symptoms. (wikipedia.org)
Spinal tumors may develop within the spinal cord parenchyma, directly destroying tissue, or outside the cord parenchyma, often compressing the cord or nerve roots. (msdmanuals.com)
Transcutaneous electrical nerve stimulation (TENS) may control radicular pain from spinal cord tumors and is a useful alternative to narcotic analgesics. (health-care-clinic.org)
Nerve tracts most vulnerable to mechanical pressure include the corticospinal and spinocerebellar tracts and the posterior spinal columns. (medscape.com)
The best chance for recovery depends on how soon you relieve pressure from the spinal nerve roots. (joionline.net)
The symptoms seen are due to spinal nerve compression and weakening of the vertebral structure. (gloucestershirespinalsurgery.com)

Tumor location, necrosis, mitosis and the Ki-67 index were related to the survival of the ependymomas, but Ki67 was the only independent prognostic factor. (nih.gov)

This assesses not only the location of the tumor(s) but also their relationship with the spinal cord and the risk of cord compression. (gloucestershirespinalsurgery.com)

We present 4 men who had tumors causing low back pain radiating to the leg: a 70-year-old with metastatic squamous cell carcinoma of the lung, a 20-year-old with aneurysmal bone cyst of the vertebral column, a 52-year-old with retroperitoneal sarcoma and a 32-year-old who also had retroperitoneal sarcoma. (tau.ac.il)

Most symptoms from spinal tumors occur due to compression of the spinal cord as it plays a primary role in motor and sensory function. (wikipedia.org)
Anterior decompression and stabilization of the spine as a treatment for vertebral collapse and spinal cord compression from metastatic malignancy. (ajnr.org)
Surgical treatment of spinal cord compression in kidney cancer. (ajnr.org)
If the tumor is slowly progressive, or If it's treated before the cord degenerates from compression, symptoms are likely to disappear, and complete restoration of function is possible. (health-care-clinic.org)
Neoplastic disease that involves the spine with spinal cord compression may be devastating. (medscape.com)
Isolated extradural Rosai-Dorfman disease of the thoracic spine: A rare cause of spinal cord compression: Case report. (jbstjournal.com)
Incontinence and decreased sensitivity in the saddle area (buttocks) are generally considered warning signs of spinal cord compression by the tumor. (gloucestershirespinalsurgery.com)
Steroids (e.g. corticosteroids) may be administered if there is evidence of spinal cord compression. (gloucestershirespinalsurgery.com)

Mrs A was transferred to Hospital 2 on 1 Month10, where she was diagnosed with multiple myeloma and underwent spinal stabilisation surgery. (hdc.org.nz)

Medulloblastoma is defined by the World Health Organization (WHO) as "an embryonal neuroepithelial tumor arising in the cerebellum or dorsal brainstem, presenting mainly in childhood and consisting of densely packed small round undifferentiated cells with mild to moderate nuclear pleomorphism and high mitotic count. (medscape.com)
The medulloblastoma has been defined by the World Health Organization (WHO) as a "malignant, invasive embryonal tumor of the cerebellum with preferential manifestation in children , predominantly neuronal differentiation, and inherent tendency to metastasize via CSF [cerebrospinal fluid] pathways. (medscape.com)

The spinal cord is surrounded by three layers known as the spinal meninges. (wikipedia.org)

Anatomy17

Organisms9

Diseases147

Chemicals and Drugs18

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Psychiatry and Psychology1

Phenomena and Processes27

Disciplines and Occupations1

Information Science4

Health Care7

Benign13

Diagnosis8

Sacrum2

Soft tissue tumors1

Lesions11

Astrocytomas5

Deficits referable to the spinal cord2

Primary spinal11

Cavitation within the spinal cord2

Biomarkers1

Extradural tumors are metastatic1

Metastases5

Cord or cauda equina compression1

Degenerative disease1

Metastasis5

Intracranial5

Neurological1

Patients22

Lesion7

Oncology3

Resection1

Meningiomas3

Pediatric1

Cancers4

Disorders3

Intramedullary tumors4

Symptoms of spinal cord compression in1

Epidural5

Bone Tumors2

Lymphoma1

Cauda equina3

Clinical6

Invading the parenchyma1

Neurologic3

Corresponding vertebrae1

Neurosurgery1

Lower extremity1

Prostate2

Intradural tumors3

Extramedullary tumors2

Nerve6

Ependymomas1

Location of the tumor1

Lung1

Compression8

Multiple myeloma1

Embryonal2

Meninges1