Tumor recurrence neoplasms multiple primary. Medical search. Frequent questions

Subsequent radiotherapy in case of incompletely resected tumors can be an important option to avoid recurrence or metastasis even though this occurs rarely. (hindawi.com)
The status of lymph node involvement is a major component of the tumor, node, metastasis (TNM) staging system. (researchgate.net)
Management of these tumors is challenging in view of nonspecific symptoms, unusual presentation and high incidence of metastasis. (biomedcentral.com)
After 3-years of follow-up, the patient developed recurrence in infracolic omentum and a liver metastasis. (biomedcentral.com)
Because of the heterogenous and aggressive nature many of them present with recurrence and visceral metastasis. (biomedcentral.com)
Extended liver surgery is recommended especially for isolated liver metastasis with a long free gap between primary tumor and the liver metastasis. (journal-jmsr.net)
Adenoid cystic carcinoma of the submandibular gland, locoregional recurrence, and a solitary Liver metastasis More than 30 years since primary diagnosis. (journal-jmsr.net)
Conclusion: Local recurrence after treatment of breast cancer with mastectomy+radiotherapy+/-systemic therapy is associated with a significantly higher risk of distant metastasis and death. (who.int)

Because cytology alone is not highly sensitive for detection of low grade urothelial carcinoma and recurrence of the disease, several adjunct markers and urine based tests for urothelial carcinoma have been developed, which can help in the final diagnosis. (medsci.org)
The diagnosis and treatment of the tumor are also discussed. (scirp.org)
The aim of this report is to analyze the histological features, diagnosis and treatments of the tumor. (scirp.org)
Median tumor size was 3 cm, and a majority of the patients had a palpable mass at diagnosis. (medpagetoday.com)
Intralesional resection and reconstruction were performed at another institution in September 2009 (Fig.?1C, D). Evaluation of the entire specimen from the curettage confirmed the histologic diagnosis giant cell tumor of bone (Fig.?1E, F). Open in a separate window Fig.?1ACF The preoperative (A) AP radiograph and (B) T1-weighted MR image show a lytic mass. (conferencedequebec.org)
FGF-23 levels were significantly increased, and total body magnetic resonance imaging (MRI) revealed a tumor mass located at the distal tibia leading to the diagnosis of tumor-induced osteomalacia (TIO). (hindawi.com)
Diagnosis of TIO is often extremely difficult since tumors can be too small for detection by conventional radiological methods. (hindawi.com)
The treatment and diagnosis of many cutaneous tumors is continually changing, and the role of clinicians (eg, primary care physicians, dermatologists, plastic surgeons, pathologists) focuses on an accurate diagnosis and a thorough understanding of the clinical sequelae. (medscape.com)
In addition, these rare cutaneous tumors are often difficult to diagnose based solely on the physical examination findings, and the proper diagnosis relies on excisional biopsy with histologic studies. (medscape.com)
She was taken for exploratory laparotomy with provisional diagnosis of malignant ovarian tumor. (scirp.org)
Presenting symptoms of primary cardiac sarcomas can be non-specific, and the most common method of initial diagnosis is echocardiography. (acc.org)
At the time of diagnosis, approximately 30% of patients with SCLC will have tumors confined to the hemithorax of origin, the mediastinum, or the supraclavicular lymph nodes. (cancer.gov)
19 ] Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but most lung tumors can be classified by light microscopic criteria. (cancer.gov)
Without treatment, SCLC has the most aggressive clinical course of any type of pulmonary tumor, with a median survival from diagnosis of only 2 to 4 months. (cancer.gov)
In this article, the authors provide an overview of current concepts of clinicopathologic characteristics, specific molecular diagnosis, and general treatment strategies for these rare embryonal tumors of childhood. (medlink.com)
Recent advances in the molecular diagnosis and treatment of pineoblastoma, a rare embryonal tumor of the pineal gland with particular penetrance in infants and young children, are also highlighted in this review. (medlink.com)
CT scan and MRI showed a liver tumor and the diagnosis of intrahepatic cholangiocarcinoma was made regarding imaging features. (journal-jmsr.net)

Osteochondromas can present as solitary lesions, or as multiple lesions in the setting of hereditary multiple exostoses, an autosomal dominant disorder. (appliedradiology.com)
Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
Clinically, superficial bladder tumors (stages Ta, Tis and T1) account for 75-80% of bladder neoplasms, while the remaining 15-20% are invasive (T2, T3, T4) or metastatic lesions at the time of presentation. (centerwatch.com)
It proved to be a valid biomarker especially in detecting squamous intraepithelial lesions in cervical liquid-based samples and in discerning these lesions from their mimickers, as well as in ovarian, endometrial, vulvar, primary and metastatic melanomas, breast, pancreatic and renal cell carcinomas. (medsci.org)
Even now, however, cases reported as multiple meningiomas include a variety of conditions from which these lesions must be differentiated. (thejns.org)
Phyllodes tumors account for fewer than 1% of all breast lesions. (medpagetoday.com)
To achieve a 1 cm margin of ablated tissue around each lesion, multiple ablation courses may be performed, depending on the size of the lesions and the time required to complete the treatment. (knowcancer.com)
Three months later, a cervical MRI showed progression of the tumor, along with new lesions in the thoracic/lumbar spine plus intracranial punctate nodular tumors. (surgicalneurologyint.com)
She underwent disease reevaluation 4 weeks after the completion of radiation, which showed improvement in the spinal tumor and no new metastatic lesions. (surgicalneurologyint.com)
In addition, an MRI of the brain revealed multiple punctate, nodular enhancing lesions in the subarachnoid space. (surgicalneurologyint.com)
Case reports in the literature report clear cell acanthomas with multiple lesions, (ie, polypoid clear cell acanthoma). (medscape.com)
Extranodal Rosai-Dorfman disease with multiple spinal lesions: Arare presentation. (jbstjournal.com)
Vascular lesions in the hand may be secondary to local pathology (e.g. tumour, malformation, trauma, iatrogenic cause, or drug injection), a proximal source of emboli (e.g. dissections or aneurysms), or systemic diseases with vascular compromise (e.g. rheumatic and vaso-occlusive diseases). (springer.com)
Brain tumors may be congenital in children younger than 3 years of age and range from benign complex lesions to highly malignant neoplasms. (medlink.com)
Necropsy showed several flattened and smooth tumorous lesions on the inner aspects of the upper and lower lips, as well as multiple small, partly ulcerated nodules at the gingival margin of the upper and lower jaw ( Figure 1 , panel B). (cdc.gov)

The peritoneum is a common site of metastases for gastrointestinal tumors that predicts a poor outcome. (stanford.edu)
In addition to primary malignancies, the skin can also be a major site for metastases of internal cancers. (medscape.com)
It has a high propensity for multiple local recurrences and bony metastases. (lookformedical.com)
The primary infection of alveolar echinococcosis is in the liver, usually the right lobe, but direct extension to contiguous organs, as well as hematogenous metastases to the lungs and brain is not uncommon. (cdc.gov)
Symptoms and signs may result from the location of the primary local invasion or compression of adjacent thoracic structures, distant metastases, or paraneoplastic phenomena. (cancer.gov)

Its therapeutic use is limited to the treatment of hypercalcemia and Paget's osteopathy, and as a tumor marker in medullary carcinoma. (teknon.es)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
Clear cell carcinoma of the bladder is a rare tumor of the bladder. (biomedcentral.com)
Here we present a case of 68-year-old woman with primary clear cell carcinoma of the bladder, who underwent repeat TUR-BT and tumor recurrence. (biomedcentral.com)
In the present report, a case of clear cell carcinoma of the bladder with repeat recurrence is presented. (biomedcentral.com)
Skin malignancies, Merkel cell carcinoma and rare appendageal tumors. (medscape.com)
Adenoid cystic carcinoma (ACC) is a rare malignant tumor. (journal-jmsr.net)
Prevalence of Parathyroid Carcinoma and Atypical Parathyroid Neoplasms in 153 Patients With Multiple Endocrine Neoplasia Type 1: Case Series and Literature Review. (cdc.gov)

Benign granular cell tumors have a recurrence rate of 2% to 8% when resection margins are deemed clear of tumor infiltration. (wikipedia.org)
Evaluate the nature and duration of response of patients with primary or metastatic liver neoplasms, who are not candidates for surgical resection, treated with radiofrequency interstitial tissue ablation. (knowcancer.com)
The patient underwent tumor resection and allograft reconstruction at another center, as shown in (C) AP and (D) lateral radiographs. (conferencedequebec.org)
therefore, a proximal tibal en bloc resection was performed in August 2010 (Fig.?2C, D). The histologic features of the specimen were consistent with a benign giant cell tumor of bone (Fig.?2E). (conferencedequebec.org)
The mean final Musculoskeletal Tumor Society functional scores were greater after extended intralesional versus resection treatment (29.5 versus 25.1). (lww.com)
After resection of the tumor, hypophosphatemia and the increased levels of FGF-23 normalized within a few days. (hindawi.com)
Tumor resection of PMTMCTs is the therapy of choice. (hindawi.com)
Complete tumor resection is suggested for recurrent cases and long-term follow-up is strongly recommended. (biomedcentral.com)
For patients with recurrent SCTAT, complete recurrent tumor resection (RTR) was the main treatment of choice. (biomedcentral.com)

Both malignant and benign versions of the tumor exist, where malignant tumors are characterized histologically by features such as spindling, high nuclear to cytoplasmic ratios, pleomorphism, and necrosis. (wikipedia.org)
A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. (curehunter.com)
In histologically typical giant cell tumor of bone, without former radiotherapy, sarcomatous change has been reported in less than 1% of patients [24]. (conferencedequebec.org)
Histologically the tumor showed the mass to be a malignant epitheioid gastrointestinal stromal tumor with mitoses in 8 - 9 of 10 high-power fields ( Figure 1 ). (scirp.org)

A systematic literature review was done to determine the relationship between elevated CRP and prognosis in people with solid tumors. (nih.gov)
In other solid tumors (lung, pancreas, hepatocellular cancer, and bladder) an elevated CRP also predicted prognosis. (nih.gov)
The pathology is associated with early recurrence and a poor prognosis. (surgicalneurologyint.com)
Despite the high risk of recurrence, SCTAT prognosis is relatively favorable. (biomedcentral.com)
Patients 55 years with small tumors confined to the thyroid have an excellent prognosis. (msdmanuals.com)

Nalesnik et al (2001) noted that PTLDs of T- or NK-cell origin have been described, and late-arising EBV-negative lymphoid tumors have become more frequently reported in patients with PTLD. (medscape.com)
Whole-genome bisulfite sequencing of tumor infiltrating and blood CD4+ T-cell from GBM patients showed 13571 differentially methylated regions and a distinct methylation pattern of methylation of tumor infiltrating CD4+ T-cells with significant inter-patient variability. (oncotarget.com)
Three patients developed nonmalignant recurrences with localised teratoma differentiated, rendered disease-free after surgery. (nih.gov)
Removing the testicle fails to cure many patients with high-risk primary testicular cancer since undetectable cancers are often present elsewhere. (nih.gov)
In patients with known disease, it provides important information for staging, evaluation of response to therapy, identification of recurrence or complications of therapy. (eurorad.org)
Over 70% of patients affected with superficial tumors will have one or more recurrences after initial treatment, and about one-third of those patients will progress and eventually succumb to their disease. (centerwatch.com)
We propose to assess the use of a multiple mutation-based assay, using DNA from exfoliated cells in the urine of patients, to establish the sensitivity and specificity in tumor detection compared to cystoscopy and cytology. (centerwatch.com)
All patients harboring tumors and scheduled to have a cystectomy, cystoscopy,or nephroureterectomy will be eligible for this study. (centerwatch.com)
Sequential digital dermoscopy documentation can also be used for short- and long-term follow-up of patients with multiple atypical nevi for the detection of melanoma and to reduce the number of unnecessary excisions. (medscape.com)
The purpose of our study was to develop modern epidemiological data for adult patients completing an appendectomy for UA secondary to an appendiceal neoplasm (AN). (cancerindex.org)
Patients who present with metastatic disease or with primary sites other than the skin have signs and symptoms related to the affected organ system(s). (medscape.com)
Recurrence risk was similar between patients who underwent second operations, regardless of initial margin status, and those with positive margins who did not have second operations, Laura H. Rosenberger, MD, of Duke University Medical Center in Durham, North Carolina, and co-authors reported in the Journal of Clinical Oncology . (medpagetoday.com)
During median follow-up of 36.7 months, 18 patients had recurrences (3.3%), which were local in 15 cases. (medpagetoday.com)
Evaluate the ability of dynamic magnetic resonance imaging (MRI) to assess the effects of this therapy on tumor blood flow and tumor vascular density in these patients. (knowcancer.com)
Patients are followed at 6 weeks, every 3 months for 1 year, and then every 6 months for 2 years or until evidence of recurrence. (knowcancer.com)
It is not clear if our patients malignant transformation of a giant cell tumor of bone while receiving denosumab treatment was caused by denosumab, but it is important to be aware of the possibility if more cases occur. (conferencedequebec.org)
Future studies should focus on the safety of high-dose denosumab administration in patients with a benign unresectable giant cell tumor of bone. (conferencedequebec.org)
The patients postoperative course was uneventful until January 2013, when a followup radiograph and CT showed a new local soft tissue recurrence in the popliteal fossae (Fig.?3A). (conferencedequebec.org)
Future research must address ways to improve the prediction of kidney cancer recurrence to better inform patients, says an expert from the Royal Free London NHS Foundation Trust. (cancernetwork.com)
Giving ipilimumab with nivolumab may work better in treating patients with HIV associated classical Hodgkin lymphoma or solid tumors compared to ipilimumab with nivolumab alone. (ucsd.edu)
Chondrosarcoma is the most common primary malignant bone tumor in patients older than 25 years [ 35 ]. (lww.com)
Although intermediate- and high-grade tumors have a survival rate of 40% to 60%, low-grade tumors result in long-term survival in as much as 90% of patients [ 11, 13, 14, 18, 20, 37 ]. (lww.com)
In recent literature, Gallium Dotatate PET has emerged as a virtually ideal investigation to localize tumors causing TIO as well and performed better than F-FDG PET/CT in some studies and seems to be a promising diagnostic tool in patients in whom 111In-octreotide SPECT/CT prior failed to detect a tumor [ 15 , 16 ]. (hindawi.com)
Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm of the central nervous system that generally arises intracranially in patients under 2 years of age. (surgicalneurologyint.com)
Recurrence rate was 46.2%, and 38.5% of patients experienced multiple recurrences. (biomedcentral.com)
Among these cases, 36.5% were associated with PJS and tumors in these patients were usually benign, multifocal, bilateral, calcified, and very small or even microscopic in size. (biomedcentral.com)
Of the 13 patients with SCTAT, eight cases were treated for primary disease and five cases were referred from other hospitals because of recurrence after unilateral salpingo-oophorectomy. (biomedcentral.com)
The slides of original ovarian tumors in patients with recurrence were reviewed by pathologists in our hospital. (biomedcentral.com)
For patients with primary SCTAT, treatment in our hospital was mainly unilateral salpingo-oophorectomy. (biomedcentral.com)
Considering that only few patients with gastrointestinal stromal tumors have been reported in the obstetrical and gynecological literature, the awareness of such an entity by the obstetricians-gynecologists is necessary in order to facilitate coordinated approach with the general surgeons and oncologists for the optimal care of the patients. (scirp.org)
Background The Spanish Melanoma Group (GEM) developed a national registry of patients with melanoma infected by SARS-CoV-2 ( GRAVID ).Methods The main objective was to describe the COVID-19 fatality rate in patients with melanoma throughout the pandemic, as well as to explore the effect of melanoma treatment and tumor stage on the risk of COVID-19 complications. (unav.edu)
Primary malignant cardiac tumors tend to occur in young patients with a mean age of 44 years and are evenly divided between the sexes. (acc.org)
We perform cardiac magnetic resonance angiography, chest and abdominal computed tomography, as well as a whole body positron emission tomography on all patients suspected of primary malignant cardiac tumors. (acc.org)
The clinical presentation of patients with primary left heart sarcoma depends on the anatomic location and extent of the tumor and is not influenced by histology. (acc.org)
1 ] Patients with tumors that have spread beyond the supraclavicular areas are said to have extensive-stage disease (ED). (cancer.gov)
Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACERx study. (researchgate.net)
ARMC5 Alterations in Patients With Sporadic Neuroendocrine Tumors and Multiple Endocrine Neoplasia Type 1 (MEN1). (cdc.gov)
Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
The tumor is often more aggressive in older patients. (msdmanuals.com)
The tumor spreads via lymphatics to regional lymph nodes in one third of patients and may metastasize to the lungs. (msdmanuals.com)
Many other areas of active research on this topic are ongoing, including investigations into improved selection criteria for patients undergoing SLNB based on features of the primary tumor, refinements in histopathologic and molecular evaluation of the sentinel node (SN), the prognostic importance of positive non-SNs and quality of life following the procedure, to name a few. (medscape.com)
Patients were assessed for Local recurrence up to 5 years. (who.int)
After a median follow up of 34 months (range: 9-67 months), out of total 198 patients, 8.6% patients developed local recurrence. (who.int)
In which 6.5% (10 patients out of 152) in upfront surgery group and 15.2% (7 patients out of 46) in LABC group developed local recurrence. (who.int)
So, total 5% (10 patients) in upfront surgery group and 3.5% (7 patients) in LABC group out of 198 total patients developed local recurrence. (who.int)

Approximately 90% of malignant tumors arising in the bladder are of epithelial origin, the majority being transitional cell carcinomas. (centerwatch.com)
Müllerian adenosarcoma (MA) is a rare mixed and low malignant tumor of female genital system, and is a biphasic differential tumor that is composed of admixed benign epithelial and sarcomatoid mesenchymal components. (scirp.org)
Separately, deletion of GCC increased tumor growth by releasing a restriction on the cell cycle normally constraining epithelial cell proliferation. (jefferson.edu)
This article focuses mainly on nonmelanoma skin cancers, with an emphasis on rare benign and malignant epithelial, dermal, and adnexal tumors. (medscape.com)
One of the most common benign epithelial tumors is seborrheic keratosis /senile keratosis, which is a hereditary lesion that appears in persons aged more than 30 years. (medscape.com)
On the other hand, clear cell acanthoma is a rare, benign epithelial cutaneous tumor. (medscape.com)

Other studies showed that only a positive margin predicted an increased risk of local recurrence and no effect of increasingly wider margins, the authors continued. (medpagetoday.com)

Pan-HDAC inhibitors exhibit significant inhibitory activity against multiple myeloma, however, their clinical applications have been hampered by substantial toxic side effects. (bvsalud.org)
In this second part of the series, we explain how to distinguish a select group of primary malignant bone tumors requiring further imaging and clinical workup from benign, tumor-like conditions. (appliedradiology.com)
In this clinical corelative study, we found that Glioblastoma (GBM) induces multi- and mixed-lineage immune response in the tumor microenvironment. (oncotarget.com)
Müllerian adenosarcomas are rare tumors with non-specific clinical features, and this forms a circumstance that poses significant challenges to the clinical practice or even delayed treatment when women presented with complaints of abdominal pain and irregular vaginal bleeding from the endometriosis postoperatively. (scirp.org)
Multiple large clinical series have shown that local recurrence is associated with positive surgical margins. (medpagetoday.com)
Clinical Relevance Denosumab has become a valuable adjunct for treatment of recurrent or unresectable giant cell tumor of bone. (conferencedequebec.org)
He is also involved in other areas of clinical oncology as well as in translational research on immunology and biomarkers on solid tumors. (unav.edu)
1 The clinical incidence of these tumors is about 1 in every 500 cardiac surgical cases in large centers. (acc.org)
We divide primary cardiac sarcoma into three clinical groups based on their site of presentation: right heart sarcomas, left heart sarcomas, and pulmonary artery (PA) sarcomas. (acc.org)
Jejunal leiomyosarcoma is a rare variety of malignant small bowel tumor and a clinical presentation with intussusception is unusual. (biomedcentral.com)
Distinct Clinical Characteristics in Young-Onset Pancreatic Neuroendocrine Tumor. (cdc.gov)
Clinical Profile and Mutations Associated with Multiple Endocrine Neoplasia-Type1 (MEN1) and Their First-Degree Relatives at Risk of Developing MEN1: A Prospective Study. (cdc.gov)
Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2). (cdc.gov)

1 Department of Solid Tumor Oncology, The Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio, United States of America. (nih.gov)
To demonstrate safety and feasibility of ipilimumab and nivolumab at the standard doses of drug in solid tumor and relapsed refractory HIV-classical Hodgkin lymphoma (cHL) participants with human immunodeficiency virus (HIV) infection given the possibility of increased toxicity based on immune activation, co-morbidity, or interference with highly active antiretroviral therapy (HAART) therapy. (ucsd.edu)
Solid Tumor Dose Expansion and cHL Cohorts) III. (ucsd.edu)

These tumors of dogs and, rarely, cats are most frequently identified on the head (including ears, lips, and oral cavity) and extremities of mature adult to senior animals. (merckvetmanual.com)
Infrequently, extracutaneous plasmacytomas may be locally invasive or multiple (or both), especially when they occur in the oral cavity. (merckvetmanual.com)
Lipomas represent about 1 to 5 percent of all neoplasms of the oral cavity. (aafp.org)
Kaposi's sarcoma herpesvirus (KSHV), a member of the genus Rhadinovirus , is the causative agent of Kaposi sarcoma ( 1 ), an endothelial neoplasm of the dermis, oral cavity and intestinal organs. (cdc.gov)

Early stage bladder tumors have been classified into two groups with distinct behaviors and different molecular profiles: Low-grade tumors (always papillary and usually superficial), and high-grade tumors (either papillary or non-papillary and often invasive). (centerwatch.com)

Introduction A giant cell tumor of bone is a primary benign but locally aggressive neoplasm [14]. (conferencedequebec.org)
Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm that constitutes approximately 6% of pediatric central nervous system (CNS) tumors. (surgicalneurologyint.com)

The remaining urine will be stored to evaluate biomarkers for the detection of tumor presence or progression using protein-based analyses. (centerwatch.com)
Is Relative Quantification Dispensable for the Measurement of MicroRNAs as Serum Biomarkers in Germ Cell Tumors? (iiarjournals.org)

SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
GISTs (Gastrointestinal stromal tumors) are most common mesenchymal neoplasms of gastrointestinal tract. (scirp.org)

Together with the uniform over-expression of GCC in human tumors, and the standard of care in which hormone deficiencies are treated by replacement therapy, the role of GCC as a tumor suppressor underscores the potential of oral administration of GCC ligands for targeted prevention and therapy of colorectal cancer. (jefferson.edu)

These tumors, on occasion, may appear similar to neoplasms of renal (relating to the kidneys) origin or other soft tissue neoplasms. (wikipedia.org)

Subsequent microscopic examination and immunohistochemical analysis revealed a phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) showing a positive expression of somatostatin receptor 2A (SSTR2A), CD68, and Periostin. (hindawi.com)
The cause of TIO are usually small, slowly growing tumors of mesenchymal origin (phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) [ 5 , 7 - 10 ]. (hindawi.com)
The patient was diagnosed with a metastatic phosphaturic mesenchymal tumor. (jbjs.org)
Oncogenic osteomalacia secondary to a metastatic phosphaturic mesenchymal tumor in the talus: A case report and review of the literature. (jbjs.org)

SCTAT accounted for 1.4% of ovarian sex cord stromal tumors, with an average onset age of 22.6 years. (biomedcentral.com)
Background: Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors that may mimic ovarian tumor on presurgical testing. (scirp.org)

The common embryonal brain tumor medulloblastoma and the rare atypical rhabdoid teratoid tumor are well-defined entities in terms of their histopathological features, immunophenotype, and genetic profiles, as are other brain tumors occurring in this age range, including choroid plexus tumors and infant gliomas, and they are discussed in separate articles. (medlink.com)
Although uncommon in children younger than 2 years of age, primary CNS tumors at this age comprise almost 15% of all childhood brain tumors. (medlink.com)

C ysts are frequently associated with glial or metastatic tumors. (thejns.org)

Unlike traditional breast cancers, granular cell tumors are mostly found in the upper inner quadrant of the breast. (wikipedia.org)
In 2016, the U.S. Preventive Services Task Force (USPSTF) concluded there is not enough evidence to recommend for or against routine screening (total body examination by a primary care physician or patient self-examination) for early detection of skin cancers in asymptomatic general adult populations. (medscape.com)
Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
Cancer stemness is linked to more aggressive disease, recurrence, and worse patient outcomes in several cancers. (lu.se)

Specific risk factors for melanoma include having an atypical mole, multiple (ie, ≥100) moles, and a family history of melanoma. (medscape.com)
Li L, Patel M, Nguyen HS, Doan N, Sharma A, Maiman D. Primary atypical teratoid/rhabdoid tumor of the spine in an adult patient. (surgicalneurologyint.com)

Breast granular cell tumors arise from intralobular breast stroma and occurs within the distribution of the cutaneous branches of the supraclavicular nerve. (wikipedia.org)
Primary Cutaneous Neuroendocrine Tumors Ceruminous gland tumors are discussed in Tumors of the Ear Canal. (merckvetmanual.com)
reticulum cell sarcomas, cutaneous nodular amyloidosis) are relatively common cutaneous tumors. (merckvetmanual.com)
Cutaneous lymphosarcoma may occur as a disease in which the skin is the initial and primary site of involvement, or it may be secondary to systemic, internal disease. (merckvetmanual.com)
Cutaneous tumors encompass a vast array of malignancies, from neuroendocrine to lymphoid. (medscape.com)
The origin of cutaneous tumors can be simplistically divided into 3 major categories: epidermal, dermal, and adnexal (see image below). (medscape.com)

Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
To preliminarily assess objective response rates associated with treatment for commonly represented solid tumors (Kaposi sarcoma, anal cancer , and lung cancer ) and relapsed refractory HIV-cHL. (ucsd.edu)
Dr. Martin Algarra areas main of interest have been the therapeutic development of immunotherapy and targeted therapies in Oncology, mainly in melanoma, sarcoma, and rare tumors. (unav.edu)
Of the malignant tumors, about 75% are sarcoma. (acc.org)
The animal had multiple oral tumors characterized by proliferation of latent nuclear antigen 1-positive spindle cells and was not co-infected with immunosuppressive simian viruses, suggesting that it had Kaposi sarcoma caused by this novel rhadinovirus. (cdc.gov)

World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). (curehunter.com)

Pancreatic Neuroendocrine Neoplasm Associated with a Familial MAX Deletion. (cdc.gov)

Growing evidence suggests that the interaction between the genomic/epigenomic aberrations in cancer cells and the surrounding microenvironment, composed of immune and stromal cells, contributes to the development of tumor invasion via mechanisms such as the so-called "angiogenic switch,"[3-5] creating multiple opportunities for therapeutic intervention. (cancernetwork.com)
The aim of this thesis was to evaluate how microenvironmental cues affect the interactions between the tumor microenvironment and glioma stem-like cells in glioblastoma. (lu.se)

However with an incidence ranging from 1.4% to SRI 31215 TFA 6.6%, most cases follow radiation therapy or multiple local recurrences [1, 3, 9, 12, 18]. (conferencedequebec.org)
1% of all Gastrointestinal (GI) tumors and its incidence is approximately 10 - 20 per million people per year. (scirp.org)

2 With the exception of one case, 6 all tumors were contained within the spinal canal. (thejns.org)
Primary spinal AT/RT in an adult is rare. (surgicalneurologyint.com)
Primary spinal AT/RT in the adult patient is rare. (surgicalneurologyint.com)
5 9 ] Primary spinal AT/RT, especially within an adult patient, is rare. (surgicalneurologyint.com)
They can present as large tumors occupying contiguous cerebral lobes or as primary pineal, brainstem, or spinal cord tumors. (medlink.com)

A few PTLDs are of T-cell origin, Hodgkin type, or, rarely, plasma cell neoplasms such as multiple myeloma. (medscape.com)
Granular cell tumors are typically solitary and rarely larger than three centimeters. (wikipedia.org)
H istorically , primary intracranial meningiomas rarely metastasize extracranially. (thejns.org)
Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. (scirp.org)
It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g. (lookformedical.com)
RDD rarely affects bone as a primary or even secondary form of the disease. (jbstjournal.com)

Extranodal lymphoma is classified as primary if involvement is confined to a single organ and immediately adjacent lymph nodes. (eurorad.org)
Primary gastrointestinal (GI) lymphoma is an uncommon disease, accounting for approximately 20% of all extranodal lymphomas. (eurorad.org)

Surgical excision, radiotherapy, and/or systemic treatments can be selected depending on patient's status and tumour stage. (unav.edu)

13-15 Local recurrence is uncommon but can be seen in cases of inadequate surgical management or malignant transformation. (appliedradiology.com)
Treatment for these tumors targets local control using localized techniques described above. (merckvetmanual.com)
Wide surgical margins did not reduce local recurrence of phyllodes breast tumors, and re-excision of negative margins for benign tumors offered no apparent benefits, according to a review of 550 cases. (medpagetoday.com)
The overall recurrence rate was 3.3%, consisting of 15 local recurrences and three distant recurrences. (medpagetoday.com)
Based on the totality of available data, we do not recommend re-excision of a negative margin for benign PT, regardless of negative margin width, as progressively wider surgical margins do not reduce local or distant recurrences. (medpagetoday.com)
While we suspect a positive margin will similarly not impact LR (local recurrence) for benign PT, we recommend awaiting forthcoming prospective data to support this hypothesis. (medpagetoday.com)
However, adequate margin width remains controversial, as some series have suggested that a tumor-free margin is sufficient to prevent local recurrence. (medpagetoday.com)
A recent meta-analysis showed an association between positive margins and local recurrence only for malignant PTs. (medpagetoday.com)
One local recurrence developed in each treatment cohort and neither transitioned to a higher grade of tumor. (lww.com)
Early detection and treatment of primary tumours is crucial to limit progression and local invasion of deep tissues. (unav.edu)
Suspicion of malignancy leads to both careful local evaluation of the tumor and its extent and the search for systemic involvement. (acc.org)
Foot radiographs at that time demonstrated persistent osteoporosis but no evidence of local tumor recurrence. (jbjs.org)
As breast cancer treatment is multimodality approach Radiation therapy has significant impact on prevention of local recurrence. (who.int)
So, purpose of the study is to assess 5 year rates of local recurrence following post-operative 2D Radiotherapy treatment planning. (who.int)

Primary management of chondrosarcoma typically consists of surgical intervention, as the tumor is relatively resistant to radiation and chemotherapy. (appliedradiology.com)
Chondroblastomas are benign chondroid neoplasms that typically affect the epiphyses of the long bones. (appliedradiology.com)
Medulloblastoma is the most common embryonal brain tumor, whereas other embryonal tumor types are considered "rare" and typically affect infants and very young children. (medlink.com)

The cancer assays to be tested use DNA analysis and antibodies to specific proteins as well as functional assays for proteins to attempt to identify bladder tumor presence. (centerwatch.com)
The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
[ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
An evolving paradigm expanding the genetic basis of cancer suggests that developmental programs indelibly imprint restricted repertoires of homeostasis, forming the substrate for lineage-dependent tumor induction by deregulation of tissue-specific survival pathways. (jefferson.edu)
Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. (ucsd.edu)
Tumors or cancer of the NOSE . (lookformedical.com)
Tumors or cancer of the PARANASAL SINUSES . (lookformedical.com)
We recently reviewed our experience with the surgical treatment of 96 primary cardiac sarcomas over a 25-year period for the Houston Methodist Hospital/MD Anderson Cancer Center combined multidisciplinary cardiac tumor group. (acc.org)
This project aims to decipher lung cancer evolution and address the primary study endpoint. (researchgate.net)
In the context of public health, oral cancer represents one of the most aggravating conditions of oral health, representing 5% of all neoplasms. (bvsalud.org)

In these cases, FGFR-23 levels are increased and immunohistochemical analysis of the tumor is positive [ 1 , 3 , 11 ]. (hindawi.com)

However, proliferative growth and development of an ulcer indicates likely malignancy as this type of tumor can be either benign or malignant. (wikipedia.org)
Regarding the histological type of tumor, there was a wide variation between studies. (bvsalud.org)

The primary method for treatment is surgical, not medical. (wikipedia.org)
Most of these tumors are locally confined, and complete but conservative surgical excision is the treatment of choice. (merckvetmanual.com)
When tumors are multiple or when surgical excision is not feasible, radiation therapy appears to be the best secondary treatment. (merckvetmanual.com)
For tumors resistant to radiation and for those animals unable to receive radiation therapy, systemic treatment with administration of chemotherapeutic agents, including melphalan, chlorambucil, cyclophosphamide, and glucocorticoids, have been recommended and have yielded long-term survival. (merckvetmanual.com)
We also examined the role of CRP to predict treatment response and tumor recurrence. (nih.gov)
In addition there is also evidence to support the use of CRP to help decide treatment response and identify tumor recurrence. (nih.gov)
Treatment varies according to the type and stage of tumour. (cancerindex.org)
Dorfmann et al and Coolican et al reported low recurrence rates after arthroscopic treatment of the knee and no postoperative stiffness with simple excision of loose bodies. (medscape.com)
However, while there are relatively few reported side effects, the safety of denosumab and adverse SRI 31215 TFA events seen with higher doses, as used in SRI 31215 TFA treatment of giant cell tumors of bone are not well defined. (conferencedequebec.org)
Although surgery is the standard primary treatment, denosumab, a monoclonal antibody drug that inhibits RANKL, has shown considerable activity regarding disease and symptoms in cases of recurrent and metastatic giant cell tumor of bone [4]. (conferencedequebec.org)
We describe the case of a patient with a benign recurrent giant cell tumor of bone who had a secondary malignant giant cell tumor of bone develop during treatment with denosumab. (conferencedequebec.org)
Based on the decreased biologic aggressiveness of low-grade cartilage neoplasms, several studies have suggested intralesional treatment may be adequate for Grade I chondrosarcomas [ 1, 4, 12, 19, 38 ]. (lww.com)
For tumors that cannot be located, medical treatment with phosphate supplements and active vitamin D (calcitriol or alpha calcitriol) is a therapeutic option [ 9 ]. (hindawi.com)
Owing to the rarity of sex cord tumor with annular tubules (SCTAT), it is difficult to recognize SCTAT clinically and there is no standard treatment. (biomedcentral.com)
Unilateral salpingo-oophorectomy is a feasible treatment for primary SCTAT cases with intact capsules and without PJS. (biomedcentral.com)
The purpose of this paper is to summarize our experience with the evaluation and treatment of primary malignant cardiac tumors. (acc.org)
Ventricular tumors are the least common and generally lead to extensive evaluation prior to any treatment. (acc.org)
In secondary echinococcosis, larval tissue spreads from the primary site and new cysts develop after spontaneous or trauma-induced cyst rupture or after release of viable parasite material during invasive treatment procedures. (cdc.gov)
Due to the unique features of the population affected by these entities, rare embryonal tumors deserve specific understanding, comprehensive diagnostic tools, and the development of much-needed novel tailored treatment approaches prioritizing less-toxic therapies to the immature nervous system. (medlink.com)
Despite treatment, tumors invariably recur, and the recurring tumor is resistant to therapies. (lu.se)
Optimal treatment for clinically localized melanoma requires surgical control of the primary site and accurate staging of the regional nodal basin with sentinel lymph node biopsy (SLNB). (medscape.com)
Optimal treatment for melanoma requires knowledge of a large, continually changing body of literature that contains significant contributions from multiple specialties. (medscape.com)

Most primary infections in humans consist of a single cyst. (cdc.gov)

The distal ileum is the most common site due to its greater amount of lymphoid tissue and just 0.8-2% of all primary GI lymphomas occur in the duodenum [1, 2]. (eurorad.org)
Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. (scirp.org)
It has been well recognized that malignant transformation of giant cell tumor of bone may occur. (conferencedequebec.org)
The predominant component of this tumor has intermediate morphologic features between granulosa cell tumors and Sertoli cell tumors and focal differentiation into either of these tumor types may occur [ 2 ]. (biomedcentral.com)
Most primary left heart sarcomas are reported to occur in the left atrium, and this is supported by our experience in which 22 of 24 (92%) occurred in the left atrium and 2 of 24 (8%) occurred in the left ventricle. (acc.org)

all received second-line chemotherapy and surgery and three remained recurrence-free at 5 yr. (nih.gov)

For recurrent, invasive tumors, more aggressive attempts at excision or electroporation may be required. (merckvetmanual.com)
Recurrent tumors were mostly ipsilateral to the primary tumor and located in retroperitoneum. (biomedcentral.com)

The most frequent bone tumors, osteochondromas represent 20-50% of benign tumors and 10-15% of all bone tumors. (appliedradiology.com)
The rate of occurrence of these tumors is highest in the developed countries, ranking as the sixth most frequent neoplasm. (centerwatch.com)
The frequent cause of death is the rupturing of the tumor, causing the animal to bleed out. (ivis.org)

This presence of melanin provides pigmentation to the benign tumor, and this occurrence has been termed pigmented clear cell acanthoma. (medscape.com)

These cases were retrospectively collected and reviewed by searching the ovarian tumor database. (biomedcentral.com)

Lipomas are common benign fatty tumors composed of mature fat cells that can develop almost anywhere in the body. (aafp.org)

The currently accepted nomenclature is solitary fibrous tumor. (medscape.com)

They are second only to clival meningiomas in surgical mortality and morbidity rates, failure of total removal, and high rate of recurrence. (thejns.org)

A high CRP was prognostic in 90% (127 of 141) of the reports in those groups of tumors. (nih.gov)
CRP was also prognostic in most reports in other solid tumors primary sites. (nih.gov)
The most important prognostic indicator for stage I and II tumors is thickness, so a full-thickness biopsy must be obtained for adequate pathologic interpretation. (medscape.com)
The first wave had the highest number of registered cases and COVID-19 mortality.Conclusion Tumor stage or melanoma treatments are non-significant prognostic factors for COVID-19 mortality. (unav.edu)

Granular cell tumors (GCTs) affect females more often than males. (wikipedia.org)

Chondrosarcoma, a malignant chondroid tumor, is the third-most common primary malignant bone tumor. (appliedradiology.com)
After CT, a guided biopsy showed a benign giant cell tumor of bone. (conferencedequebec.org)
The histologic features of the recurrence corresponded to a benign giant cell tumor of bone, just as had the previous specimens (Fig.?3B). (conferencedequebec.org)
Tumor-induced osteomalacia (TIO) is a rare, acquired paraneoplastic disorder characterized by a renal phosphate leak leading to hypophosphatemia and deranged bone turnover. (hindawi.com)
Primary Rosai-Dorfman disease of bone: A clinicopathologic study of 15 cases. (jbstjournal.com)
Extranodal Rosai-Dorfman disease presenting as incidental bone tumor: A case report. (jbstjournal.com)

Angiogenesis, the recruitment of new blood vessels from the pre-existing vascular matrix, is now a well-established prerequisite for tumor progression. (cancernetwork.com)

To the best of our knowledge, our case is the sixth case that primary adenosarcomas arising in vaginal endometriosis and it is the first case living without chemo-therapy or radiotherapy. (scirp.org)
However, the resected margins showed no tumor-free tissue, and therefore a subsequent postoperative radiotherapy was performed. (hindawi.com)

Fine-needle aspiration cytology (FNAC) was first introduced by Martin and Ellis 4 and has been used as an easy and safe procedure for diagnosing primary and metastatic mediastinal diseases. (allenpress.com)

The tumor cells stain positively for S-100 as they are of Schwann cell origin. (wikipedia.org)
Notably, compound 30 has exhibited outstanding HDAC6 inhibitory activity (IC50 = 4.63 nM) and superior antiproliferative effects against human multiple myeloma cells, specifically RPMI-8226. (bvsalud.org)
Although their derivation was long debated, neoplastic cells characteristically express cytoplasmic immunoglobulin and may produce primary amyloid, leaving little doubt as to their lymphoplasmacytic origin. (merckvetmanual.com)
CD4+ helper T (Th) cells play a critical role in shaping anti-tumor immunity by virtue of their ability to differentiate into multiple lineages in response to environmental cues. (oncotarget.com)
The methylation changes also resulted in transcriptomic changes with 341 differentially expressed genes in CD4+ tumor infiltrating T-cells compared to blood. (oncotarget.com)
Analysis of specific genes involved in CD4+ differentiation and function revealed differential methylation status of TBX21, GATA3, RORC, FOXP3, IL10 and IFNG in tumor CD4+ T-cells. (oncotarget.com)
Analysis of lineage specific genes revealed differential methylation and gene expression in tumor CD4+ T-cells. (oncotarget.com)
Interestingly, we observed dysregulation of several ligands of T cell function genes in GBM tissue corresponding to the T-cell receptors that were dysregulated in tumor infiltrating CD4+ T-cells. (oncotarget.com)
Our results suggest that GBM might induce epigenetic alterations in tumor infiltrating CD4+ T-cells there by influencing anti-tumor immune response by manipulating differentiation and function of tumor infiltrating CD4+ T-cells. (oncotarget.com)
Thus, further research is warranted to understand the role of tumor induced epigenetic modification of tumor infiltrating T-cells to develop effective anti-GBM immunotherapy. (oncotarget.com)
The primary objective of this study is to evaluate the utility of emerging technologies in the detection of bladder tumor cells using non-invasive approaches utilizing voided urine samples. (centerwatch.com)
Microscopically, most of the tumor cells were arranged in tubular glands, microcysts or fine papillae, partly in diffuse sheets or solid nests (Figure 2 ). (biomedcentral.com)
Most tumor cells were in cuboidal or columnar shape and hobnail cells were seen containing abundant clear cytoplasm (Figure 4 ). (biomedcentral.com)
The muscular layer of the bladder was invaded by tumor cells. (biomedcentral.com)
Liposarcomas are malignant tumors of the lipocytes ( fat cells ) and are not commonly found in pet birds. (ivis.org)
Dermoid cysts are firm, slow-growing benign tumors that contain mature skin cells and are covered with a thick wall. (aafp.org)
Examination of cells whether from a primary or secondary site, including fluids aspirated using endoscopes or needles. (who.int)
The tumors are highly vascularized and characterized by proliferation of spindle cells that contain KSHV DNA and antigen ( 2 , 3 ). (cdc.gov)
Tumors are not simply a compilation of molecularly and phenotypically identical neoplastic cells. (lu.se)
4. Has provided tumor tissue that demonstrates PD-L1 expression in =1% of tumor cells (TPS =1%) as assessed by IHC at a central laboratory. (who.int)

Vaginal granular cell tumors are generally rare. (wikipedia.org)
Malignancy is rare and constitutes only 2% of all granular cell tumors. (wikipedia.org)
A subtype of nonconventional "surface" osteosarcomas, periosteal osteosarcomas are rare, malignant neoplasms representing about 1% of all osteosarcomas. (appliedradiology.com)
[ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
There are few reports available on this rare disease, and no cases with recurrence were reported. (biomedcentral.com)
In rare cases, a venous sampling of FGF-23 is necessary to detect the tumor [ 9 , 17 ]. (hindawi.com)
Extramammary Paget's disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. (karger.com)
Sex cord tumor with annular tubules (SCTAT) is a rare and distinctive ovarian sex cord-stromal tumor (SCST), accounting for approximately 2.3% of SCSTs [ 1 ]. (biomedcentral.com)
Primary cardiac tumors are rare, occurring in about 0.001-0.3% of autopsies. (acc.org)
Rare embryonal tumors may be congenital and can arise along the neuraxis. (medlink.com)
Malignant small bowel tumors are very rare and leiomyosarcoma accounts for less than 15% of the cases. (biomedcentral.com)

Anatomy3

Organisms4

Diseases114

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment69

Phenomena and Processes18

Disciplines and Occupations1

Information Science4

Health Care20

Metastasis8

Diagnosis17

Lesions19

Metastases5

Carcinoma8

Resection9

Histologically4

Prognosis5

Patients45

Epithelial6

Risk of local recurrence1

Clinical13

Solid tumor3

Oral cavity4

High-grade tumors1

Aggressive neoplasm2

Biomarkers2

Mesenchymal neoplasms2

Colorectal Cancer1

Soft tissue ne1

Phosphaturic mesenchymal tumor4

Stromal tumors2

Brain tumors2

Metastatic tumors1

Cancers4

Atypical2

Cutaneous6

Sarcoma5

Pathology1

Neuroendocrine1

Microenvironment2

Incidence2

Spinal5

Rarely6

Lymphoma2

Patient's1

Local14

Typically3

Cancer10

Immunohistochemical1

Type of tumor2

Treatment22

Humans1

Occur5

Surgery1

Recurrent2

Frequent3

Benign tumor1

Ovarian tumor1

Common benign1

Solitary1

Surgical1

Prognostic4

GCTs1

Bone6

Progression1

Radiotherapy2

Cytology1

Cells20

Rare11