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  • EGCG
  • Emerging data amassed from various laboratories around the world suggests that green tea, particularly its major polyphenolic constituent (−)-epigallocatechin-3-gallate (EGCG), possesses remarkable cancer chemopreventive and therapeutic potential against various cancer sites in animal tumor bioassay systems and in some human epidemiologic studies. (aacrjournals.org)
  • invasion
  • 11 Schorge and associates followed FIGO staging and measured depth of invasion from the surface of the tumor or overlying benign epithelium down to the deepest point using a calibrated 40x magnification field. (glowm.com)
  • In addition to activating Fyn, this interaction with Y580-SHP2 localizes Fyn to sites of receptor engagement, which is required for α6β4-dependent invasion. (umassmed.edu)
  • neoplastic
  • and (d) a borderline association was found between the high mean value of laminin receptor immunopositivity and p53 accumulation in neoplastic cell nuclei (P = 0.05). (ac.be)
  • immune
  • The role of an autologous tumor-specific immune control contributing to the variable length of survival in CLL is poorly understood. (semanticscholar.org)
  • Humoral immune response and immunoglobulin G Fc receptor genotype are associated with better clinical outcome following idiotype vaccination in follicular lymphoma patients regardless of their response to induction chemotherapy. (semanticscholar.org)
  • cell
  • The aim of this study was to assess common phenotypic features of nine tumor cell lines established from BM of patients with cancer of the prostate (four cell lines), breast (two cell lines), lung (two cell lines), and colon (one cell line) using immunocytochemistry, flow cytometry, and reverse transcription-PCR. (aacrjournals.org)
  • The tumor origin of the cell lines was supported by the expression of the ErbB2 oncogene (seven of nine) and MAGE mRNA (eight of eight). (aacrjournals.org)
  • Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation. (abcam.com)
  • Several cell surface molecules have been identified as receptors for Ad attachment and entry. (pubmedcentralcanada.ca)
  • In this review, we discuss the various cell surface molecules that are implicated as receptors for virus attachment and internalization. (pubmedcentralcanada.ca)
  • Each fiber monomer is comprised of an amino-terminus that is noncovalently anchored to the penton base, a carboxy-terminus globular domain that binds to the cell surface receptor, and a rod-like shaft that varies in length according to the Ad serotype. (pubmedcentralcanada.ca)
  • dissemination
  • In tumors such as ovarian cancer, in which cellular adhesion to the matrix plays a critical role in the establishment of metastases ( 8 ), such inhibitors may prevent cancer dissemination. (aacrjournals.org)
  • biological
  • The biological and physiological functions of TGF β , the founding member of this family, and its receptors are of central importance to human diseases, particularly cancer. (hindawi.com)
  • invasive
  • Of clinical relevance, phospho-Y580-SHP2 and phospho-Y418-SFK could be used as potential biomarkers of invasive breast cancer because their expression are elevated in high-grade breast tumors. (umassmed.edu)
  • We hypothesize that patients who develop local recurrence and/or second primary oral tumors are those whose surgical margins or uninvolved buccal mucosa harbor molecular changes that are found in oral dysplasia or invasive OSCC. (aacrjournals.org)
  • prostate
  • Human prostate tumors were established by intracardiac injection into male severe combined immunodeficient (SCID) mice and treatment with J8H antibody was initiated after one week. (blogspot.com)
  • vessels
  • What are 4 features of tumor vessels that make them different from normal vessels? (cram.com)
  • identical
  • Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. (nih.gov)
  • mice
  • Continuous Delivery of Neutralizing Antibodies Elevate CCL2 Levels in Mice Bearing MCF10CA1d Breast Tumor Xenografts. (abcam.com)
  • The IL-1ß Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice. (abcam.com)
  • metastasize
  • The choice of 5 and 7 mm as the maximum depths and horizontal spread, respectively, was based on the correlation between the volume of a tumor and its potential to metastasize. (glowm.com)
  • Primary
  • The initial attachment of Ad to its primary receptor, which differs among Ad subgroups ( Table 1 ), is considered as one of the primary determinants to Ad tropism. (pubmedcentralcanada.ca)