Tumor Necrosis Factor-alphaPromoter Regions, GeneticBase SequenceMolecular Sequence DataGene Expression RegulationReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IPolymorphism, GeneticReceptors, Tumor Necrosis Factor, Type IIInterleukin-1CytokinesRNA, MessengerLipopolysaccharidesCells, CulturedInterleukin-6NF-kappa BNecrosisTranscription FactorsTransforming Growth Factor alphaCell LineInterferon-gammaMacrophagesMice, Inbred C57BLTranscription, GeneticLymphotoxin-alphaRecombinant ProteinsSignal TransductionMonocytesApoptosisTumor Cells, CulturedMice, Inbred BALB CInflammationGene ExpressionTumor Necrosis FactorsAntibodies, MonoclonalTransfectionArthritis, RheumatoidInterleukin-10Reverse Transcriptase Polymerase Chain ReactionInterleukin-8Cell Line, TumorDose-Response Relationship, DrugMice, KnockoutTime FactorsTumor Necrosis Factor Decoy ReceptorsAntigens, CDDNA-Binding ProteinsUp-RegulationAntirheumatic AgentsDisease Models, AnimalMacrophage ActivationSynovial MembraneInterleukin-1betaLeukocytes, MononuclearEnzyme-Linked Immunosorbent AssayBlotting, WesternMembrane GlycoproteinsDown-RegulationT-LymphocytesFibroblastsFlow CytometryNeutrophilsInflammation MediatorsCell SurvivalEndotoxinsCell DivisionDrug SynergismMacrophages, PeritonealI-kappa B ProteinsProtein BindingPolymerase Chain ReactionImmunohistochemistryEnzyme ActivationTranscriptional ActivationDNA PrimersLiverAnti-Inflammatory AgentsGenotypeAmino Acid SequencePentoxifyllineDNAMutationTranscription Factor RelABinding SitesI-kappa B KinaseKineticsMice, Inbred C3HPhosphorylationEndothelium, VascularInterleukin-12TNF Receptor-Associated Factor 2Nitric OxideImmunoglobulin GBlotting, NorthernGenes, ReporterHeLa CellsIntercellular Adhesion Molecule-1Tumor Markers, BiologicalRecombinant Fusion ProteinsCell Differentiation