Umbilical VeinsHuman Umbilical Vein Endothelial CellsEndothelial CellsEndothelium, VascularCells, CulturedCell AdhesionEndotheliumNeovascularization, PhysiologicE-SelectinVascular Cell Adhesion Molecule-1Tumor Necrosis Factor-alphaCell MovementVascular Endothelial Growth Factor AUmbilical ArteriesNeovascularization, PathologicVeinsIntercellular Adhesion Molecule-1Umbilical CordRNA, MessengerAngiogenesis InhibitorsNitric Oxide Synthase Type IIICell Adhesion MoleculesSignal TransductionThrombinCell ProliferationDose-Response Relationship, DrugVascular Endothelial Growth Factor Receptor-2Cell LineNitric OxideCell DivisionCulture Media, ConditionedCell SurvivalTime FactorsInterleukin-1Endothelial Growth FactorsUp-Regulationvon Willebrand FactorPhosphorylationGene Expression RegulationEpoprostenolStress, MechanicalVascular Endothelial Growth FactorsChorioallantoic MembraneAortaSaphenous VeinApoptosisNF-kappa BBlotting, WesternCell Line, TumorReverse Transcriptase Polymerase Chain ReactionLymphokinesAntigens, CD31Interleukin-8Enzyme InhibitorsEnzyme ActivationCoculture TechniquesThromboplastinMonocytesGene ExpressionAngiogenesis Inducing AgentsFetal BloodProto-Oncogene Proteins c-aktTransfectionRecombinant ProteinsRNA, Small InterferingCattleReceptors, Cell SurfaceCapillariesNeutrophilsAntigens, CDFibroblast Growth Factor 2Portal VeinHistamineFlow CytometryMicrocirculationDown-RegulationP-SelectinLamininAntibodies, MonoclonalReceptors, Vascular Endothelial Growth FactorReactive Oxygen SpeciesImmunohistochemistryReceptors, ThrombinThrombomodulinDrug CombinationsMolecular Sequence DataVaricose VeinsCapillary PermeabilityNitric Oxide SynthaseLipopolysaccharidesIntegrin alphaVbeta3Mice, Inbred C57BLEndostatinsCell Culture TechniquesMice, NudeCell CommunicationPlasminogen InactivatorsAngiopoietin-2KineticsEnzyme-Linked Immunosorbent Assay