Cell AgingCell Line, TumorTumor BurdenMice, NudeCell ProliferationNeovascularization, PathologicNeoplasms, ExperimentalXenograft Model Antitumor AssaysTumor Suppressor Protein p53Neoplasm TransplantationTumor Markers, BiologicalTransplantation, HeterologousTumor Necrosis Factor-alphaCell DivisionMammary Neoplasms, ExperimentalNeoplasmsMice, Inbred BALB CMice, SCIDTumor Suppressor ProteinsNeoplasm MetastasisCyclin-Dependent Kinase Inhibitor p16Genes, Tumor SuppressorApoptosisSignal TransductionTumor MicroenvironmentWilms TumorBrain NeoplasmsCell Transformation, NeoplasticMice, Inbred C57BLFibroblastsMelanoma, ExperimentalGene Expression Regulation, NeoplasticAdenocarcinomaCell Growth ProcessesFibrosarcomaCarcinoid TumorColonic NeoplasmsNeuroendocrine TumorsReverse Transcriptase Polymerase Chain ReactionAngiogenesis InhibitorsCells, CulturedSarcoma, ExperimentalRNA, MessengerBlotting, WesternCyclin-Dependent Kinase Inhibitor p21Neoplasm ProteinsTelomeraseCell LineTelomereCell CycleRNA, Small InterferingTime FactorsCarcinoma, Lewis LungImmunohistochemistryAgingTransfectionDown-RegulationBreast NeoplasmsCell MovementDisease Models, AnimalPancreatic NeoplasmsGliomaDisease ProgressionLiver NeoplasmsSkin NeoplasmsAntigens, NeoplasmLung NeoplasmsMutationMammary Neoplasms, AnimalTumor Cells, CulturedPlant LeavesAntibodies, MonoclonalMice, Transgenicbeta-GalactosidaseDNA DamageFlow CytometryGlioblastomaPhenotypeRNA InterferenceKidney NeoplasmsCarcinoma, Ehrlich TumorUp-RegulationGenetic TherapyModels, BiologicalGene Expression ProfilingAging, PrematureCarcinoma, Squamous CellDose-Response Relationship, DrugBone NeoplasmsGastrointestinal Stromal TumorsGene ExpressionMice, KnockoutEndothelial CellsTumor Suppressor Protein p14ARFRetinoblastoma ProteinGene Knockdown TechniquesMolecular Sequence DataTumor Stem Cell AssayGenes, rasDNA, Neoplasm