Hepatoid and mixedMinimally invasive adenocarcinomaProduced by tumor cellsNeoplasmSUPPRESSOR GENESInvasiveEpithelialSubtypeCarcinomaMetastasesMetastaticResectionHistologicDuctalBiopsiesRecurrenceImmunohistochemicalPatternsPancreatic CancerLungPapillaryHistologyDiagnosisLesionArisesPrimaryPatientsInvasionCancersRarelyRemnantsColumnarCellsExaminationClear cellRareCommonDevelopmentArticlesManagementReportDiseaseSpecificFigure
Hepatoid and mixed1
- The histologic appearance of bladder adenocarcinoma can be enteric, signet ring, mucinous, clear cell, hepatoid and mixed types. (biomedcentral.com)
Minimally invasive adenocarcinoma1
- For resection specimens, new concepts are introduced such as adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) for small solitary adenocarcinomas with either pure lepidic growth (AIS) or predominant lepidic growth with ≤ 5 mm invasion (MIA) to define patients who, if they undergo complete resection, will have 100% or near 100% disease-specific survival, respectively. (qxmd.com)
Produced by tumor cells1
- Parathyroid hormone-related peptide (PTHrP) is produced by tumor cells and functions similarly to parathyroid hormone (PTH). (wikipedia.org)
Neoplasm1
- The high proportion of mitotic cells and resemblance to well-differentiated adenocarcinoma of the large intestine suggested that this neoplasm was adenocarcinoma rather than adenoma. (hindawi.com)
SUPPRESSOR GENES1
- Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. (nshealth.ca)
Invasive1
- In the 4th edition of WHO classification of tumors of female reproductive organs, primary villoglandular mucinous adenocarcinoma is defined as a primary invasive glandular epithelial tumor of intestinal type and the synonyms are cloacogenic carcinoma or cloacogenic adenocarcinoma [ 1 ]. (hindawi.com)
Epithelial1
- GB epithelial tumors tend to behave similarly to other GI adenocarcinomas. (medscape.com)
Subtype2
- The terms BAC and mixed subtype adenocarcinoma are no longer used. (qxmd.com)
- Treatment of this lung cancer is based upon the specific subtype and the extent of spread from the primary tumor. (wikipedia.org)
Carcinoma6
- This new adenocarcinoma classification is needed to provide uniform terminology and diagnostic criteria, especially for bronchioloalveolar carcinoma (BAC), the overall approach to small nonresection cancer specimens, and for multidisciplinary strategic management of tissue for molecular and immunohistochemical studies. (qxmd.com)
- The differential diagnosis includes glandular differentiation of transitional cell carcinoma and direct extension or metastatic spread of adenocarcinoma arising primarily from the colon, prostate, appendix or endometrium. (biomedcentral.com)
- The most common paraneoplastic syndromes associated with adenocarcinoma of the lung are described below: Hypercalcemia of malignancy is more common in squamous cell carcinoma of the lung, but can occur in adenocarcinoma as well. (wikipedia.org)
- Clear cell carcinoma of the bladder is a rare tumor of the bladder. (biomedcentral.com)
- Here we present a case of 68-year-old woman with primary clear cell carcinoma of the bladder, who underwent repeat TUR-BT and tumor recurrence. (biomedcentral.com)
- CK7, CK20, CDX2 and MUC2 Immunohistochemical staining used to distinguish metastatic colorectal carcinoma involving ovary from primary ovarian mucinous adenocarcinoma. (novodiax.com)
Metastases1
- The peritoneum is a common site of metastases for gastrointestinal tumors that predicts a poor outcome. (stanford.edu)
Metastatic3
- Staging evaluation revealed no evidence of metastatic disease but at the time of radical cystectomy, periaortic lymphadenopathy and a locally extensive tumor mass were identified. (biomedcentral.com)
- citation needed] Adenocarcinoma, like other forms of lung cancer, is usually advanced or metastatic at time of diagnosis. (wikipedia.org)
- Mucinous tumors may produce vague or punctate calcification in the primary tumor or in metastatic foci that may be visible on plain films. (medscape.com)
Resection3
- The patient was treated by tumor resection. (hindawi.com)
- In 1946, Waugh and Clagett described a formal en-bloc resection of the gallbladder with the common bile duct (CBD), gastric antrum, duodenum, and pancreatic head performed as a one-stage procedure, which we recognize today as the classic pancreaticoduodenectomy. (medscape.com)
- Although innumerable details of pancreaticoduodenectomy yield to continued innovation, a comprehensive discussion of intraoperative variants (ie, duct to mucosa vs invagination of the pancreaticojejunal anastomosis, diverse approaches to vein resection and reconstructions, nuances of each enteric anastomosis, and modifications of Roux-en-Y reconstructions, to name a few) is beyond the scope of this article. (medscape.com)
Histologic2
- Adenocarcinoma is the most common histologic type of lung cancer. (qxmd.com)
- The pathophysiology of adenocarcinoma is complicated, but generally follows a histologic progression from cells found in healthy lungs to distinctly dysmorphic, or irregular cells. (wikipedia.org)
Ductal1
- Aruj Chawla, DO discusses a study that brings about a novel method to analyze vascular involvement in pancreatic ductal adenocarcinomas. (arrs.org)
Biopsies2
- Prostate biopsies showed mucinous adenocarcinoma in six of eight cores with large collections of mucin dissecting the prostatic parenchyma. (biomedcentral.com)
- Bladder washings and biopsies revealed copious amounts of mucin with associated malignant nests and single cells also consistent with mucinous adenocarcinoma. (biomedcentral.com)
Recurrence1
- This complex mixture of cell types forms the biological context for therapeutic response and tumor recurrence. (bvsalud.org)
Immunohistochemical1
- Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 and Mucin 6 were negative. (hindawi.com)
Patterns1
- Telomere Dysfunction, Chromosomal Instability and Cancer -- Genetic Instability and Disease Prognostication -- Causes of Chromosomal Instability -- Patterns of Chromosomal Aberrations in Solid Tumors -- Yeast as Models of Mitotic Fidelity -- The Diverse Effects of Complex Chromosome Rearrangements and Chromothripsis in Cancer Development. (nshealth.ca)
Pancreatic Cancer1
- Her research program includes hyperpolarized 13C MR spectroscopic imaging (MRSI) to assess renal tumor aggressiveness and diffuse renal disease (nephropathy), as well as quantitative imaging in pancreatic cancer. (ucsf.edu)
Lung11
- International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (qxmd.com)
- To address advances in oncology, molecular biology, pathology, radiology, and surgery of lung adenocarcinoma, an international multidisciplinary classification was sponsored by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society. (qxmd.com)
- This new classification strategy is based on a multidisciplinary approach to diagnosis of lung adenocarcinoma that incorporates clinical, molecular, radiologic, and surgical issues, but it is primarily based on histology. (qxmd.com)
- With declining smoking rates in developed countries and knowledge gains made through molecular profiling of tumors, the emergence of new risk factors and disease features will lead to changes in the landscape of lung cancer epidemiology. (scienceopen.com)
- The advent of low-dose helical computed tomography (CT) altered the landscape of lung-cancer screening, with studies indicating that low-dose CT detects many tumors at early stages. (scienceopen.com)
- Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. (wikipedia.org)
- Lung adenocarcinoma is further classified into several subtypes and variants. (wikipedia.org)
- Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations. (wikipedia.org)
- Like many lung cancers, adenocarcinoma of the lung is often advanced by the time of diagnosis. (wikipedia.org)
- This is caused by compression of vasculature by the lung tumor that restricts blood return from the upper body. (wikipedia.org)
- Less than 1% of patients with adenocarcinoma of the lung will exhibit this finding, but when it does occur, it is a poor prognostic factor. (wikipedia.org)
Papillary1
- Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
Histology1
- Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. (scienceopen.com)
Diagnosis3
- Once a lesion or tumor is identified with various imaging modalities, such as computed tomography (CT) or X-ray, a biopsy is required to confirm the diagnosis. (wikipedia.org)
- The pathological diagnosis was clear cell adenocarcinoma of the bladder. (biomedcentral.com)
- Immunologic Markers in the Differential Diagnosis of Small Round Cell Tumors from Lymphocytic Lymphoma and Leukemia. (novodiax.com)
Lesion1
- Concomitant cystitis glandularis occurs in the majority of cases, but is not considered a definitive precursor lesion since adenocarcinoma can develop in the absence of cystitis glandularis and only a small number of bladders with cystitis glandularis actually develop malignancies [ 2 ]. (biomedcentral.com)
Arises1
- Villoglandular mucinous adenocarcinoma arises in the surface epithelium of the vulva. (hindawi.com)
Primary4
- Primary adenocarcinomas of the vulva are rare and especially the villoglandular mucinous adenocarcinoma of intestinal type is rare variant of vulvar adenocarcinoma. (hindawi.com)
- We report a 57-year-old Caucasian man presenting with penile discharge for 30 years following ileal conduit surgery for neurogenic bladder, and who was found to have primary mucinous adenocarcinoma of his defunctionalized bladder. (biomedcentral.com)
- Primary adenocarcinoma of the urinary bladder accounts for approximately 0.5-2% of all bladder cancers [ 1 ]. (biomedcentral.com)
- We describe the fifth case of primary mucinous adenocarcinoma arising in a longstanding defunctionalized bladder. (biomedcentral.com)
Patients5
- however, more commonly, the tumor is unresectable and is rarely diagnosed preoperatively despite patients' symptoms. (medscape.com)
- Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis. (nagoya-u.ac.jp)
- Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
- In patients with a dilated pancreatic duct, a Roux-en-Y side-to-side pancreaticojejunostomy is indicated. (medscape.com)
- This comparison study shows upfront thermal ablation results in better progression-free-survival compared to delayed ablation, for patients with low tumor burden. (arrs.org)
Invasion2
- No invasion or no microinvasion of the tumor cells was seen. (hindawi.com)
- No tumor invasion was seen. (hindawi.com)
Cancers4
- Mutation of the transforming growth factor (TGF) beta receptor type II gene is common in RER+ colon and gastric cancers, but uncommon in RER+ endometrial cancers even those arising in HNPCC kindreds, suggesting that the genesis of RER+ tumors even within the same familial cancer syndrome is not the same. (medmuv.com)
- Although inactivation of both alleles of either hMSH2 or MLH1 (DNA mismatch repair genes) appears to underlie microsatellite instability in tumors of HNPCC kindreds, similar to the findings in sporadic colon cancers, sporadic endometrial cancers were not associated with mutations of any of the four known human mismatch repair genes. (medmuv.com)
- Chromosome 18q contains the DCC gene, a putative tumor suppressor gene frequently mutated in colon cancers. (medmuv.com)
- These data strongly suggest that some gene on chromosome 18, is a tumor suppressor gene in endometrial cancers. (medmuv.com)
Rarely1
- AIS and MIA are usually nonmucinous but rarely may be mucinous. (qxmd.com)
Remnants2
- The possibility that those tumors may originate from cloacal remnants has been raised [ 2 - 12 ]. (hindawi.com)
- There is the hypothesis that such misplaced remnants transformed into a tubulovillous adenocarcinoma of enteric type. (hindawi.com)
Columnar1
- Most tumor cells were in cuboidal or columnar shape and hobnail cells were seen containing abundant clear cytoplasm (Figure 4 ). (biomedcentral.com)
Cells4
- The tumor had a large proportion of mitotic cells and its resemblance to adenocarcinoma of the large intestine was striking. (hindawi.com)
- c) Tumor cells show high-grade nuclear atypia. (hindawi.com)
- Microscopically, most of the tumor cells were arranged in tubular glands, microcysts or fine papillae, partly in diffuse sheets or solid nests (Figure 2 ). (biomedcentral.com)
- The muscular layer of the bladder was invaded by tumor cells. (biomedcentral.com)
Examination1
- Microscopic examination of paraffin-embedded sections (Figure 2 ) disclosed villous adenomatous tumor in continuity with the epidermis. (hindawi.com)
Clear cell1
- As an extremely rare variant of adenocarcinoma, clear cell type affects women more often than men. (biomedcentral.com)
Rare2
- The potential for adenocarcinoma to develop in the defunctionalized bladder that is left in-situ at the time of urinary diversion is rare [ 3 - 5 ]. (biomedcentral.com)
- Hypertrophic pulmonary osteoarthropathy (HPO) is fairly rare in adenocarcinoma. (wikipedia.org)
Common1
- Transitional cell and squamous cell carcinomas are the most common but there are three reported cases of mucinous adenocarcinoma. (biomedcentral.com)
Development1
- But still the mechanisms of development of villoglandular mucinous adenocarcinoma in vulva are controversial. (hindawi.com)
Articles1
- In the published articles [ 2 ], intestinal type mucinous adenocarcinoma was also taken as a synonymous with villoglandular mucinous adenocarcinoma. (hindawi.com)
Management1
- Fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)-CT has been used to determine optimal management of biliary tumors. (medscape.com)
Report1
- We report a case of 68-year-old woman who developed this very uncommon malignant tumor. (hindawi.com)
Disease1
- See Pancreatic Adenocarcinoma Imaging: What You Need to Know , a Critical Images slideshow, to help identify which imaging studies to use to identify and evaluate this disease. (medscape.com)
Specific1
- Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. (nshealth.ca)
Figure1
- Grossly, the resected tumor from vestibule of vagina was papillomatous nodule, 4 × 2 cm in size and yellowish in color (Figure 1 ). (hindawi.com)