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  • pilocytic astrocytomas
  • Understanding the molecular basis responsible for the aggressive behaviour of hypothalamo-chiasmatic pilocytic astrocytomas is a prerequisite to setting up new molecular targeted therapies. (ed.gov)
  • We used the microarray technique to compare the transcriptional profiles of five hypothalamo-chiasmatic and six cerebellar pilocytic astrocytomas. (ed.gov)
  • Results demonstrate that cerebellar and hypothalamo-chiasmatic pilocytic astrocytomas are two genetically distinct and topography-dependent entities. (ed.gov)
  • Numerous genes upregulated in hypothalamo-chiasmatic pilocytic astrocytomas also increased in the developing chiasm, suggesting that developmental genes mirror the cell of origin whereas migrative, adhesive and proliferative genes reflect infiltrative properties of these tumours. (ed.gov)
  • Of particular interest, "NOTCH2", a gene expressed in radial glia and involved in gliomagenesis, was upregulated in hypothalamo-chiasmatic pilocytic astrocytomas. (ed.gov)
  • In order to find progenitor cells that could give rise to hypothalamo-chiasmatic pilocytic astrocytomas, we performed a morphological study of the hypothalamo-chiasmatic region and identified, in the floor of the third ventricle, a unique population of vimentin- and glial fibrillary acidic protein-positive cells highly suggestive of radial glia cells. (ed.gov)
  • Therefore, pilocytic astrocytomas of the hypothalamo-chiasmatic region should be considered as a distinct entity which probably originates from a unique population of cells with radial glia phenotype. (ed.gov)
  • spine
  • The forms of cancer ranging from lung (40 patients), astrocytoma brain tumor (26), colon (25), breast (15) to pelvis (1), spine (1) and thyroid (1) cancers, to name just a few. (glioblastomaprognosis.com)
  • His practice includes treatment of all conditions of the spine including neck and arm pain, back and leg pain, disk herniations, spinal stenosis, fractures, tumors, infections and scoliosis. (swedish.org)
  • Dr. Cobbs specializes in brian tumor surgery, minimally invasive spine surgery and neurosurgery. (swedish.org)
  • He has specific expertise in the treatment of spinal cord tumors as well as metastatic disease of the spine. (swedish.org)
  • Although primary brain tumors often transmit cancerous cells to other sites in the central nervous system (the brain or spine), they rarely spread to other parts of the body. (umm.edu)
  • astrocytic
  • The therapeutic strategy for astrocytic tumor involves surgery, irradiation, and chemotherapy [ 2 ], and this treatment regime has resulted in an increase in median progression-free and overall survival [ 3 , 4 ]. (alliedacademies.org)
  • treatment
  • Astrocytoma brain tumor treatment includes surgery, chemotherapy, radiation, radiosurgery and/or an intense drug regiment depending on the age of the patient, the patient's overall health, the patient's functional abilities, and the location, seriousness, and type of the specific astrocytoma brain tumor. (glioblastomaprognosis.com)
  • To view details of the study, the news releases at the time, or learn more about this revolutionary brain tumor treatment use for DCA go to http://www.puredca.com . (glioblastomaprognosis.com)
  • These reports explain the medical findings as well as explain why it has not yet, at the time of this writing, become a regular treatment for astrocytoma brain tumor sufferers. (glioblastomaprognosis.com)
  • The cell invasiveness decreased significantly after siRNA silenced HPA , and HPA might be a potential target for the treatment of astrocytomas. (alliedacademies.org)
  • Despite the rapid development of neuroimaging greatly helps the diagnosis and treatment of astrocytoma, and treatment technology of astrocytoma has made great progress, its clinical effect is not ideal, the main reason for which is most of astrocytomas show invasive growth, and it is difficult to cure completely by operation [ 6 ]. (alliedacademies.org)
  • Surgical excision of the maximal amount of the tumor that can be removed, without producing neurological deficits, is the appropriate treatment. (neurosurgerydallas.com)
  • He is the Director of The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment. (swedish.org)
  • An in-depth report on the causes, diagnosis, and treatment of brain tumors. (umm.edu)
  • The standard approach for treating brain tumors is to reduce the tumor as much as possible using surgery, radiation treatment, or chemotherapy. (umm.edu)
  • When associated with NF2, these tumors are usually closely observed without the need for treatment. (henryford.com)
  • survival
  • The post-operative survival is longer than other types of Astrocytomas. (neurosurgerydallas.com)
  • This work proposes MRI- and clinical information-based automated pipeline that implements various state-of-the-art image processing, machine learning, and deep learning techniques to obtain robust tumor segmentation and patient survival estimation. (springer.com)
  • Chato, L., Latifi, S.: Machine learning and deep learning techniques to predict overall survival of brain tumor patients using MRI images. (springer.com)
  • lung
  • Adenocarcinoma is the one cell type of primary lung tumor that occurs more often in non-smokers and in smokers who have quit. (docplayer.net)
  • The tumor seen here has caused obstruction of the main bronchus to left lung so that the distal lung is collapsed. (docplayer.net)
  • Oat cell carcinomas are very aggressive and often metastasize widely before the primary tumor mass in the lung reaches a large size. (docplayer.net)
  • surgery
  • Biopsies may be performed as part of surgery to remove a tumor, or as a separate diagnostic procedure. (umm.edu)
  • inoperable
  • Tumor board has rendered it inoperable due to the location. (whatnext.com)
  • The Oncologist was shocked as was the neurologist (mum didn't have a neurosurgeon as tumour inoperable) and they said it was very surprising but could maybe be down to the steroids or the 5 days of chemotherapy. (btsurvivor.com)
  • Nervous System
  • With discovery of neural stem cells (NSCs) in the central nervous system, there has been a wide speculation that a normal NSC or progenitor cell might be a principal target of mutations that lead to a brain tumour. (egms.de)
  • Neurofibromatosis is a genetic disorder that causes changes to the skin and tumors of the nervous system. (henryford.com)
  • mRNA
  • Immunohistochemical Elivision™plus two step method and Realtime-PCR method were used to detect the expression of HPA protein and mRNA in 75 cases of astrocytoma tissues and 40 cases of normal brain tissues. (alliedacademies.org)
  • malignancy
  • Previously, we reported a mouse model for malignant astrocytomas, in which germline haploinsufficiency of p53 and conditional haploinsufficiency of Nf1 tumor suppressors on the same chromosome induce the malignancy with complete penetrance (Mut3 mice in Zhu et al. (aacrjournals.org)
  • HPA is highly expressed in astrocytomas tissues, and with the increase of malignancy of tumor, the expression increases gradually. (alliedacademies.org)
  • Neurofibromatosis
  • In 2007, the Multidisciplinary Neurofibromatosis Clinic at Henry Ford Hospital received the Network Affiliate Status award from the Children's Tumor Foundation (CTF) , a national neurofibromatosis organization. (henryford.com)
  • Our Neurofibromatosis Clinic is part of the Hermelin Brain Tumor Center at Henry Ford. (henryford.com)
  • mass
  • When the mitochondria is reactivated using a DCA solution (pure DCA powder in water), the tumor mass shrunk up to 70% in just 3 weeks. (glioblastomaprognosis.com)
  • 21 The dense white encircling tumor mass is arising from the visceral pleura and is a mesothelioma. (docplayer.net)