Tumor and patients metastatic undifferentiated adenocarcinoma. Medical search. Frequent questions

The majority are carcinomas including adenocarcinomas, squamous cell carcinoma and undifferentiated carcinomas. (vin.com)
One third of patients with cancer of unknown primary origin have poorly or undifferentiated carcinoma. (medscape.com)
Nasopharyngeal part contributes a very small percentage of adenocarcinoma as the most common histopathology found here is squamous cell carcinoma. (ijorl.com)
The result of right FOR biopsy is non intestinal type adenocarcinoma, and biopsy of right neck swelling is reported as metastatic undifferentiated carcinoma. (ijorl.com)
In conclusion the approach in treatment for nasopharyngeal carcinoma (NPC) and sino-nasal adenocarcinoma differs whereby the cornerstone management for the latter one is surgical intervention compared to the former which is radiotherapy. (ijorl.com)
Ahmad A, Stefani S. Distant metastases of nasopharyngeal carcinoma: a study of 256 male patients. (ijorl.com)
Cabometyx is indicated as monotherapy for the treatment of adult patients with locally advanced or metastatic differentiated thyroid carcinoma (DTC), refractory or not eligible to radioactive iodine (RAI) who have progressed during or after prior systemic therapy. (pharmaceutical-technology.com)
Cabometyx (cabozantinib) developed for the treatment of patients with advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). (pharmaceutical-technology.com)
While the tumor is often considered to arise from neuroendocrine proliferation or possibly dedifferentiation of an acinar carcinoma, the precise etiology remains uncertain. (karger.com)
Papandreou CN, Daliani DD, Thall PF, Tu SM, Wang X, Reyes A, Troncoso P, Logothetis CJ: Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate. (karger.com)
They may either follow radiation therapy for squamous cell carcinoma, or the larynx may be the site of metastatic osteosarcoma (primary bone cancer). (wearethecure.org)
Squamous cell carcinoma of the trachea may be ulcerative or exophytic (outward growing tumor) in appearance. (wearethecure.org)
Metastatic carcinoma involving the temporal bone is an unusual occurrence. (ejao.org)
When a known cancer patient whose primary disease is controlled presents with otologic symptoms and a history of chronic mastoid infection, metastatic carcinoma of the temporal bone must be considered as an uncommon, but possible diagnosis. (ejao.org)
In spite of their aggressive biologic behavior, some ductal adenocarcinomas show bland nuclear features, making the distinction of benign lesion from an invasive carcinoma difficult, particularly on small biopsy specimens (Fig. 1). (coek.info)
Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
HPV DNA is found in two of 18 cases of squamous cell carcinoma (II %), in one of 4 cases of adenocarcinoma, and in two of 7 cases of neuro-endocrin cancers. (coek.info)
Being aware of this unusual and rare presentation of metastatic prostate carcinoma might decrease diagnostic delay and allow earlier treatment. (hindawi.com)
The diagnosis was stage IV metastatic prostate carcinoma (pM1a). (hindawi.com)
Diagnostic Comments: Noted in the endometrial cavity is an undifferentiated carcinoma. (healthdrugpdf.com)
The patient had a history of stage III endometrial carcinoma status post vaginal hysterectomy and bilateral salpingo-oophorectomy 3 months prior and chemotherapy with Taxol and carboplatin. (healthdrugpdf.com)
Undifferentiated prostate cancer, squamous cell carcinoma, and ductal transitional carcinoma also occur infrequently. (msdmanuals.com)
The coexistence of carcinomatous and sarcomatous elements within the same tumor is a rare entity, variably labeled as "carcinosarcoma", "metaplastic carcinosarcoma", "sarcomatoid carcinoma", "pseudosarcomatous carcinoma", "carcinoma with mesenchymal stroma", "carcinoma with sarcomatoid change", "spindle cell carcinoma", "pleomorphic anaplastic carcinoma" and "small cell carcinoma"[1]. (klinikitsekoura.gr)
The term carcinosarcoma implies a mixed malignant tumor that is composed of an epithelial element, typically the common form of carcinoma seen in the tissue harboring the neoplasm, close to or intermixed with a sarcomatous component. (klinikitsekoura.gr)
Traditionally, bile duct tumors located within the liver had been classified with hepatocellular carcinoma as primary liver tumors. (tri-kobe.org)
OBJECTIVES: I. Evaluate the efficacy of paclitaxel and carboplatin with amifostine on progression free survival and overall survival in patients with metastatic or recurrent epithelial endometrial carcinoma not amenable to surgery or radiotherapy. (knowcancer.com)
This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignature® test status. (ucbraid.org)
This phase II trial studies how well Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor AZD6738 works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma (RCC), urothelial carcinoma, all pancreatic cancers, endometrial cancer, and other solid tumors excluding clear cell ovarian cancer that have spread to nearby tissue or lymph nodes or other parts of the body. (ucbraid.org)
Immunohistochemical analysis of metastasis allowed to identify immunophenotypes of different types of metastatic carcinoma and melanoma and estimate the origin of unknown primary metastasis. (ungthuvn.org)
Urothelial (transitional cell) carcinoma is the most patients younger than 50 years to 81.3% in patients older common histological type of bladder cancer, accounting than 50 years (9) . (who.int)
Squamous cell carcinoma ac- rate for 31 266 patients (74% men, 26% women) with counts for about 4% of cases of bladder cancer, adenocar- urinary bladder cancer diagnosed from 1997 to 2011 was cinoma for about 2% and all other types for about 4% of 72% (10) . (who.int)

Richardson RL, Weiland LH: Undifferentiated small cell carcinomas in extrapulmonary sites. (karger.com)
Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site. (medscape.com)
New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
No case of the two large cell undifferentiated carcinomas was positive. (coek.info)

Despite the addition of CT and MRI as imaging modalities for the nasal cavity, imaging alone is not enough for a positive diagnosis and imaging features cannot identify particular tumor pathologies. (vin.com)
The future diagnosis and management of canine nasal cavity tumors likely will include molecular diagnostic techniques, molecular imaging (PET-CT, PET-MRI and potentially also HyperPET) to guide IMRT as well as species specific immune therapeutic approaches. (vin.com)
However, a substantial proportion of gastric adenocarcinomas are advanced or metastatic disease at the time of diagnosis. (biomedcentral.com)
One patient with metastatic disease died shortly after diagnosis, the other was lost to follow-up. (karger.com)
The frozen section diagnosis was at least mucinous borderline tumor. (hindawi.com)
The frozen section diagnosis was at least mucinous borderline tumor, pending adequate tissue sampling for permanent sections to rule out mucinous adenocarcinoma. (hindawi.com)
The effects of androgen deprivation seem most pronounced in patients with minimal disease at diagnosis. (basicmedicalkey.com)
Treatment for advanced prostate cancer can provide significant disease palliation for many patients for several years after diagnosis. (basicmedicalkey.com)
The patient presented with concurrent mastoid infection, which further complicated proper diagnosis. (ejao.org)
Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
Prostate cancer should always be considered in the differential diagnosis of elderly men presenting with metastatic epithelial tumors even in unusual sites. (hindawi.com)
7. Confirmed diagnosis of gastric adenocarcinoma or GEJ adenocarcinoma. (uchicagomedicine.org)
1. Diagnosis of HER2-positive G/GEJ adenocarcinoma. (uchicagomedicine.org)
Biopsies were obtained, which resulted in the diagnosis of adenocarcinoma. (klinikitsekoura.gr)
Tumor markers are tumor-derived or tumor-associated proteins, antigens, genes or hormones that can also aid in diagnosis, in the measurement of therapeutic response, in locating tumor origin or in determining recurrence. (oncolink.org)
Better survival was observed in patients with early stage and well differentiated tumours at diagnosis. (who.int)

The company's pipeline product candidates include zanzalintinib, XB002 and XL102 for the treatment of advanced or metastatic solid tumors and CBX-12 for advanced metastatic refractory solid tumors. (pharmaceutical-technology.com)
This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors. (ucbraid.org)
This phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or urothelial cancer that has spread to other places in the body (advanced). (ucbraid.org)
Combining BAY 1895344 with chemotherapy treatment (cisplatin, or cisplatin and gemcitabine) may be effective for the treatment of advanced solid tumors, including urothelial cancer. (ucbraid.org)
This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb23104, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity of XmAb23104 monotherapy and combination therapy with ipilimumab in subjects with selected advanced solid tumors. (ucbraid.org)

A subpopulation of these can be potentially curable, including patients with lymphomas, germ cell tumors, or neuroendocrine tumors. (medscape.com)
Thus, the term "carcinoid" was replaced by the term "gastroenteropancreatic neuroendocrine tumors, GEP-NETs"[ 2 ]. (wjgnet.com)

The histologic subtype, metastasis site, and certain patient characteristics can offer clues to the cancer primary. (medscape.com)
The prognosis for prostate cancer patients depends on the histologic grade, the tumor size, and the disease stage. (basicmedicalkey.com)
Biopsy methods for accurate histologic or cytologic proof of malignancy are absolutely essential to workup and subsequent management of suspected cancer patients. (oncolink.org)

The index case is being presented for its rarity and probable poor outcome in young patients and to stress on the fact that the possibility of primary prostatic adenocarcinoma should be investigated in a male presenting with bone metastasis irrespective of the age. (jpalliativecare.com)
Lymph node metastasis is an important clinical issue in AEG patients. (biomedcentral.com)
Here, we report a case of isolated distant metastasis of lung cancer to the mastoid portion of the temporal bone in a patient whose primary tumor had been treated. (ejao.org)
She had been diagnosed with large cell adenocarcinoma in the left lower lobe of the lung with no evidence of distant metastasis (pT2N0M0) and had undergone mediastinoscopy and left pneumonectomy in our hospital 3 months earlier. (ejao.org)
The Tumor-Nodal-Metastasis (TNM) Staging or Jackson Staging of Penile Cancer was documented from various African studies as shown in (Table 2 ). (biomedcentral.com)

It is a high-grade and poorly differentiated neuroendocrine tumor, usually diagnosed in advanced stages, with a poor prognosis and few therapeutic options in that setting. (mdpi.com)
PATHOLOGY Ductal adenocarcinomas are firm to hard mass lesions that are often poorly defined grossly. (coek.info)
A proportion of tumors are poorly differentiated with little or no gland formation. (coek.info)
The tumor consisted of poorly differentiated carcinomatous and spindle-shaped sarcomatous elements. (klinikitsekoura.gr)

In lymphoma and thyroid adenocarcinoma, the disease generally metastasizes to the larynx and the trachea. (wearethecure.org)
1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
In lymphomas I have conducted studies in rare aggressive primary cutaneous tumors such as gamma/delta T cell lymphoma (expanding the description of the epidermotropic variant) as well as more indolent entities such as lymphomatoid papulosis (type D) and CD4-positive small to medium size T cell lymphoproliferative disorders. (mdanderson.org)
Study design: A total 100 patients with gastric lymphoma at the K hospital. (ungthuvn.org)

In most cases, histopathologic analysis will permit classification of these tumors into those with a favorable prognosis, which are mostly approached with locoregional treatment or systemic platinum-based chemotherapy, or an unfavorable prognosis, which are treated with empirical combination regimens involiving platinum or taxane. (medscape.com)
A randomized clinical trial REGATTA which aimed to evaluate whether the addition of gastrectomy to chemotherapy improves survival for advanced gastric cancer patients with a single non-curable factor was terminated ahead of time due to the negative results from the interim analysis [ 2 ]. (biomedcentral.com)
This is a case report of a 77-year-old Spanish male patient with localized SCC of the colon, who presented a pathological complete response in the surgical specimen after neoadjuvant chemotherapy with cisplatin and etoposide. (mdpi.com)
Mismatch repair-deficient tumors do not respond well to chemotherapy applied in the neoadjuvant, adjuvant, or metastatic settings. (cancer.gov)
Chemotherapy, with docetaxel and prednisone improves survival in patients with castrate-refractory prostate cancer and is considered first-line therapy for these patients. (basicmedicalkey.com)
Part C is the open-label, randomized, controlled, 2-arm portion of the study to evaluate the efficacy and safety of tislelizumab + chemotherapy regimen (CAPOX or mFOLFOX6) ± DKN-01 in adult patients with inoperable, histologically confirmed locally advanced or metastatic G/GEJ adenocarcinoma with measurable disease (RECIST v1.1) requiring therapy. (uchicagomedicine.org)
Approximately 160 patients will be randomized in a 1:1 ratio to receive either DKN-01 in combination with tislelizumab and chemotherapy regimen (CAPOX or mFOLFOX6) (n=80) or tislelizumab in combination with chemotherapy regimen (CAPOX or mFOLFOX6) (n=80). (uchicagomedicine.org)
therefore, chemotherapy is the main treatment for unresectable PC (UR-PC) patients. (e-ce.org)
Cisplatin and gemcitabine are chemotherapy drugs that stop the growth of tumor cells by killing the cells. (ucbraid.org)

My research interests comprise cutaneous tumors with emphasis in lymphomas and melanoma. (mdanderson.org)
However, the frequency of melanoma is increasing, particularly in lighter-skinned people, and for the minority of patients diagnosed with metastatic disease, the 5-year survival rate is 35%, although the introduction of immunotherapy has doubled the median survival time for these patients. (cdc.gov)
In this cohort study of 94 patients with resected melanoma brain metastases that underwent targeted DNA sequencing, BRAF V600E variant lesions were associated with worse intracranial progression-free survival and overall survival. (cdc.gov)

Canine nasal tumors are one of the more common tumor types in dogs representing up to 1% of all cancers. (vin.com)
No staging system exists for cancers of unknown primary origin-more precisely, histologically proven metastatic malignant tumors for which the primary site cannot be identified during pretreatment evaluation. (medscape.com)
Small cell cancers with high metastatic potential and early mediastinal invasion are particularly serious. (about-health-problems.com)
The 5-year survival rate for patients with localized disease after surgical resection is 20% and for those with metastatic disease, the survival rate is only 2%.1 Only about 20% of pancreatic cancers are detected early enough to be surgically resectable. (coek.info)

Mucinous tumor is a common type of ovarian epithelial tumors. (hindawi.com)

Invasive mucinous adenocarcinoma is uncommon and usually arises in the background of benign or borderline tumors. (hindawi.com)
Histological examination revealed an invasive tumor infiltrating the full thickness of the rectal wall, as well as the perirectal fat and external sphincteric muscle fibers at the level of anal canal. (klinikitsekoura.gr)
Benign tumors are not invasive, do not spread to other areas of the body, and are easy to remove surgically. (merckvetmanual.com)

Lung cancer is a malignant tumor starting point of glandular bronchial epithelium. (about-health-problems.com)
Due to the volume of tumors and their proliferation, sometimes appear dilated superficial veins of the chest and neckline edema in case of superior vena cava compression, and a paraneoplastic syndrome (especially Schwartz-Barter's syndrome, caused by abnormal secretion of ADH by malignant tumor). (about-health-problems.com)
SWI/SNF‑related, matrix‑associated, actin‑dependent regulator of chromatin, subfamily a, member 4 (SMARCA4)‑deficient non‑small cell lung cancer (dNSCLC) is a rare malignant tumor that originates in the lungs. (spandidos-publications.com)

Gross section of an adenocarcinoma of the pancreas measuring 5 × 6 cm resected from the pancreatic body and tail. (medscape.com)
Laboratory findings in patients with pancreatic cancer are usually nonspecific. (medscape.com)
Patients with advanced pancreatic cancer and weight loss have laboratory evidence of malnutrition (eg, low serum albumin or cholesterol level). (medscape.com)
See also Pancreatic Adenocarcinoma Imaging: What You Need to Know , a Critical Images slideshow, to help identify which imaging studies to use to identify and evaluate this disease. (medscape.com)
The increased detection of pancreatic cysts in asymptomatic patients has also led to an increase in the number of pancreatic biopsies and surgical interventions. (coek.info)
PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
Triphasic pancreatic-protocol computed tomography is the best initial diagnostic test for pancreatic cancer, and on this modality these tumors appear as a hypodense solid mass. (coek.info)

Although individualized targeted therapies are routinely used for patients with lung and breast tumors, personalized medicine has not achieved the same degree of success in the pancreas. (coek.info)

Avastin, in combination with carboplatin and paclitaxel, is indicated for the first‑line treatment of patients with unresectable, locally advanced, recurrent or metastatic non-squamous non-small cell lung cancer. (avastin.com)
Metastatic adenocarcinoma presenting as isolated axillary lymphadenopathy in women is usually a manifestation of an occult breast primary cancer . (medscape.com)
Recently, evidence has emerged that palliative gastrectomy in patients with stage IV gastric cancer may offer some survival benefits. (biomedcentral.com)
Adenocarcinoma accounts for the majority of gastric cancer diagnoses, and patients with gastric adenocarcinoma often experience relatively short survival times. (biomedcentral.com)
Surgery provides a curative opportunity for a number of patients and is considered the foundation of multimodal management of gastric cancer. (biomedcentral.com)
A previous systematic review and meta-analysis of 14 studies comprising 3003 patients with incurable advanced gastric cancer revealed that palliative gastrectomy significantly improved overall survival [ 9 ]. (biomedcentral.com)
Moreover, a recent study based on the Surveillance, Epidemiology, and End Results Program (SEER) data demonstrated a survival benefit for palliative gastrectomy in gastric cancer patients with stage IV disease after balancing baseline characteristics using propensity score matching analysis [ 10 ]. (biomedcentral.com)
Cabometyx is indicated for the treatment of adult and pediatric patients 12 years of age and older with locally advanced or metastatic differentiated thyroid cancer (DTC) that has progressed following prior VEGFR-targeted therapy and who are radioactive iodine-refractory or ineligible. (pharmaceutical-technology.com)
Background - Cancer of unknown primary origin (CUP) is defined by the presence of pathologically identified metastatic disease without clinical or radiological evidence of a primary tumour. (ices.on.ca)
Material and Methods - The researchers used the Ontario Cancer Registry (OCR) and the Same-Day Surgery and Discharge Abstract Database (SDS/DAD) to identify patients diagnosed with CUP in Ontario between 1 January 2000, and 31 December 2005. (ices.on.ca)
In addition, patients with cancer of unknown primary origin are defined as patients with histologically proven metastatic malignant tumors in which the primary site cannot be identified during pretreatment evaluation. (medscape.com)
Prostate cancer is common in older patients. (jpalliativecare.com)
Most of the published data has reported poor outcome in younger patients with metastatic prostate cancer. (jpalliativecare.com)
20 - 25 ] A major pooled analysis evaluating the impact of T and N stage and treatment on survival and relapse in patients with rectal cancer who are treated with adjuvant therapy confirmed these findings. (cancer.gov)
Although the tumor was considered to have been fully resected and had not spread to any nodes, the patient died of recurrent cancer within 1 year. (medscape.com)
Androgen deprivation therapy with a luteinizing hormone-releasing hormone (LHRH) agonist plus an antiandrogen should be used prior to radiation therapy for patients with locally advanced prostate cancer to improve outcomes over radiation therapy alone. (basicmedicalkey.com)
Androgen deprivation therapy, with either orchiectomy, an LHRH agonist alone or an LHRH agonist plus an antiandrogen (combined hormonal blockade), can be used to provide palliation for patients with advanced (stage D 2 ) prostate cancer. (basicmedicalkey.com)
Because cancer cells are abnormal, this lack of cell death adds to the accumulation of cells and tumor formation. (healthywomen.org)
3) Reports previously showed that temporal bone metastases were not observed in cancer patients in which the primary tumor was adequately treated. (ejao.org)
Mediastinum and retroperitoneum are exceedingly rare sites for metastatic prostate cancer to occur. (hindawi.com)
Our patient presented with mediastinal mass as the first manifestation of prostate cancer. (hindawi.com)
In one series, mediastinal adenopathy was reported as the initial presentation in only 0.8% of patients with prostate cancer [ 2 ]. (hindawi.com)
Less frequently, patients present initially with metastatic prostate cancer. (hindawi.com)
The patient was then referred to radiology, where she received a PET/CT examination that revealed markedly hypermetabolic primary cervical cancer with metastatic lymph node involvement of a single right external iliac and two left external iliac lymph nodes. (healthdrugpdf.com)
Prostate cancer is usually adenocarcinoma. (msdmanuals.com)
Довідковий матеріал загального характеру Prostate cancer is usually adenocarcinoma. (msdmanuals.com)
Hormonal influences contribute to the course of adenocarcinoma but almost certainly not to other types of prostate cancer. (msdmanuals.com)
The incidence of the penile cancer peaks in the sixth decade of life even though it may occur in younger patients. (biomedcentral.com)
Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
It is intended as a resource to inform and assist clinicians who care for cancer patients. (tri-kobe.org)
[ 1 ] In contrast, bile duct tumors located outside of the liver had been classified with gallbladder cancer as extrahepatic biliary tract tumors. (tri-kobe.org)
Bile duct cancer may occur more frequently in patients with a history of primary sclerosing cholangitis, chronic ulcerative colitis, choledochal cysts, or infections with the liver fluke Clonorchis sinensis . (tri-kobe.org)
Intrahepatic bile duct cancer may be relatively indolent and difficult to clinically differentiate from metastatic adenocarcinoma deposits in the liver. (tri-kobe.org)
Cancer cells depart their normal microenvironment from the primary tumor site through complicated and multistep processes disseminate and colonize distant organs [ 1 ]. (intechopen.com)
This phase II trial studies how well abemaciclib works in treating patients with ovarian or endometrial cancer that has an activation of the CDK4/6 pathway and that has come back (recurrent). (ucbraid.org)
Laboratory data provide information on the functioning of specific organs and metabolic processes that may be affected in cancer patients or altered by subsequent cancer therapy. (oncolink.org)
From the abstract: 'Neoadjuvant or adjuvant immunotherapy can improve outcomes in patients with resectable non-small-cell lung cancer (NSCLC). (cdc.gov)
This study aimed to estimate the probability of survival in patients with bladder cancer in Jordan and identify fac- tors associated with survival. (who.int)
The survival of patients with bladder cancer in Jordan is comparable to that reported from developed coun- tries. (who.int)

Biopsy of the tumor showed solid flaky, nest‑like infiltrating growth. (spandidos-publications.com)
A core needle biopsy was taken from the mediastinal mass and showed epithelial tumor cells arranged in nesting pattern with focal acinar formation. (hindawi.com)
3. Documentation of elevated DKK1 mRNA expression from a fresh tumor biopsy or a biopsy obtained within the 6 months of screening. (uchicagomedicine.org)
4. Documentation of PD-L1 CPS by IHC and DKK1 mRNA expression in tumor cells by ISH from a fresh tumor biopsy (preferred) or archived tumor biopsy specimen conducted in a Sponsor designated central laboratory. (uchicagomedicine.org)
9. Tumor tissue for mandatory pre-treatment evaluation (fresh biopsy [preferred] or archived specimen). (uchicagomedicine.org)
She had an endometrial biopsy that was positive for endometrial adenocarcinoma. (healthdrugpdf.com)
This multicenter study investigated the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for MSI evaluation in patients with UR-PC. (e-ce.org)
A veterinarian can perform a fine needle aspiration of cells or a biopsy (which removes a small amount of tissue from a tumor) for evaluation. (merckvetmanual.com)

For benign tumors that are not ulcerated and do not impair the dog's normal routine, treatment may not be necessary. (merckvetmanual.com)
There are several treatment options for cancerous tumors and benign tumors that inhibit normal activities or are cosmetically unpleasant. (merckvetmanual.com)

Mast cell lesions are among the most common tumors in dogs. (wearethecure.org)

However, the decision whether to perform primary tumor surgery remains challenging for surgeons, and investigations into models that are predictive of prognosis are scarce. (biomedcentral.com)
Finally, the cut-off value of the calculated total scores based on preoperative nomograms was set and validated by comparing survival with contemporary cases without primary tumor surgery. (biomedcentral.com)
28 showed no survival benefit with gastrectomy compared to no primary tumor surgery. (biomedcentral.com)
Primary and metastatic cardiac sarcomas represent rare neoplasms with a variable clinical course. (journalmc.org)
Primary cardiac tumors are rare, with an incidence in early autopsy series from 0.001% to 0.3% [ 1 , 2 ]. (journalmc.org)
The majority of these are benign, primary malignant heart tumors accounting for less than 25% [ 3 ]. (journalmc.org)
Most cardiac tumors are metastatic and 20 - 40 times more common than primary tumors [ 4 , 8 ]. (journalmc.org)
These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
Fine-needle aspiration cytology (FNAC) was first introduced by Martin and Ellis 4 and has been used as an easy and safe procedure for diagnosing primary and metastatic mediastinal diseases. (allenpress.com)
Unlike classical lung adenocarcinoma, the primary driver genes implicated in SMARCA4-dNSCLC, as revealed by molecular detection tests, primarily involve SMARCA4, TP53, KRAS and STK11 , while the more commonly associated driver genes like EGFR, ALK and ROS1 show no marked association ( 1 ). (spandidos-publications.com)

Tumors provided for pathologic review should come from tissue that has, whenever possible, been excised, if such tissue is available and accessible. (medscape.com)
Chondrosarcomas are malignant tumors that arise in any place where there is cartilage (type of connective tissue). (wearethecure.org)
6 , 25 , 30 ] Measured in millimeters, CRM is defined as the retroperitoneal or peritoneal adventitial soft-tissue margin closest to the deepest penetration of the tumor. (cancer.gov)
No significant difference in terms of sufficient tissue acquisition for histology was observed between patients who underwent EUS-FNB and those who underwent EUS-FNA. (e-ce.org)
Therefore, it is desirable to obtain tissue samples from UR-PC patients for MSI evaluation. (e-ce.org)
10 , 11 A previous report indicated that tissue sampling using EUS-FNB was useful for MSI evaluation in UR-PC patients. (e-ce.org)
Tumors affecting the skin or the tissue just under the skin are the most commonly seen tumors in dogs. (merckvetmanual.com)
Malignant tumors can invade surrounding tissue and spread to distant organs. (merckvetmanual.com)
If malignancy is suspected, tissue surrounding the tumor will also be removed to increase the chance that none of the tumor cells are left behind. (merckvetmanual.com)

This is a Phase 2 open-label, multicenter study to be conducted concurrently in 3 Parts (Parts A, B, and C). Approximately 232 patients aged 18 years or older with inoperable, histologically confirmed locally advanced or metastatic G/GEJ adenocarcinoma with measurable disease (RECIST v1.1) requiring therapy will be enrolled in the study. (uchicagomedicine.org)

Here, we present the case of a 67-year-old male patient with incidental findings of mediastinal and retroperitoneal masses which were found to be due to metastatic prostate adenocarcinoma based on histopathology and immunohistochemical studies and later on supported by the significantly elevated Prostate Specific Antigen (PSA) levels. (hindawi.com)
The mixed nature of these tumors is confirmed by a positive immunohistochemical staining for both cytokeratins and vimentin. (klinikitsekoura.gr)

Histologically, most ductal adenocarcinomas are composed of glandlike structures embedded in an abundant desmoplastic stroma. (coek.info)

Adenocarcinoma is commonly found in lung, prostate and gastrointestinal tract. (ijorl.com)
That wild reproduction causes the formation of tumors that may block air passages in the lung and prevent it from functioning as it should. (healthywomen.org)
There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)

Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)

Findings of cardiac osteosarcoma in a patient with a pacemaker and three malignancies have not been reported before in the literature. (journalmc.org)
We report a sporadic case of an 84-year-old man with a pacemaker diagnosed with heart osteosarcoma, hepatocellular and prostatic adenocarcinoma and presenting with symptoms mimicking infective endocarditis. (journalmc.org)

Clinical staging prior to initiation of therapy: A minimum database (MDB) consisting of a complete hemogram including blood smear evaluation, biochemistry, and urinalysis, nasal and thoracic imaging by either X-ray, but preferentially CT or MRI as these are superior to conventional radiography of the nasal cavity in delineating extent of tumor. (vin.com)
We present a case of nasopharyngeal adenocarcinoma which is a very rare clinical presentation. (ijorl.com)
Reports suggest that these are usually solitary, protruding tumors found in the wall of the larynx with clinical upper respiratory obstruction. (wearethecure.org)
Treatment continues in repeating 21-day cycles until patient meets criteria for discontinuation or is no longer deriving clinical benefit. (uchicagomedicine.org)
A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid Leukemia. (cancerindex.org)

5 ] The location of a rectal tumor is usually indicated by the distance between the anal verge, dentate line, or anorectal ring and the lower edge of the tumor, with measurements differing depending on the use of a rigid or flexible endoscope or digital examination. (cancer.gov)
The rectal tumor had a diameter of 7 cm, was elastic on palpation and had a whitish-yellow cut surface. (klinikitsekoura.gr)

Treatment for a particular tumor depends largely on the type of tumor, its location and size, and the overall physical condition of the dog. (merckvetmanual.com)

Conclusion - CUP patients in Ontario have a poor prognosis. (ices.on.ca)
Correctly interpret the diagnoses of the pathologic conditions mentioned above, with a clear understanding of their value for the definition of patient prognosis and treatment. (unibo.it)
However, for patients with a KMT2A rearrangement (KMT2A-r), the prognosis appears to depend on the fusion partner gene rather than the karyotype structure. (cancerindex.org)

Circumferential resection margin (CRM) or depth of penetration of the tumor through the bowel wall. (cancer.gov)

Current study aimed to develop and validate prognostic nomograms for patients with metastatic gastric adenocarcinoma treated with palliative gastrectomy. (biomedcentral.com)
The development dataset comprised 1186 patients from the Surveillance, Epidemiology, and End Results Program who were diagnosed with metastatic gastric adenocarcinoma in 2004-2011, while the validation dataset included 407 patients diagnosed in 2012-2015. (biomedcentral.com)
Our survival nomograms for patients with metastatic gastric adenocarcinoma undergoing palliative gastrectomy can assist surgeons in treatment decision-making and prognostication. (biomedcentral.com)

Patients may have received prior neoadjuvant or adjuvant therapy as long it was completed without disease recurrence for at least 6 months since last treatment. (uchicagomedicine.org)

A 35 cm right ovarian mass submitted for intraoperative consultation was a multicystic mucinous tumor with an 8 cm area of hemorrhagic lesion between cystic locules. (hindawi.com)
A macroscopic hemorrhagic area in an ovarian mucinous tumor should be evaluated with care, and the possibility of angiosarcoma should be borne in mind. (hindawi.com)
The findings in this case may be useful for pathologists in the recognition of this uncommon type of ovarian tumors. (hindawi.com)

Compared with TURP, HoLEP had better curative efficacy at 6, 12, and 24 months after operation and lower incidence of adverse events in patients with BPH. (bvsalud.org)
However, the resulting gastroesophageal reflux disease caused by the eradication of Helicobacter pylori (among various other factors) might potentially lead to an increase in the incidence of adenocarcinoma of the esophagogastric junction (AEG) worldwide [ 5 ]. (biomedcentral.com)
Whichever date is selected, the date of only: date of first consultation at the out- incidence should not be later than the date of patient clinic because of this malignancy. (who.int)

and (3) other malignancies which are commonly developed in patients with appendiceal NETs. (wjgnet.com)
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in patients with selected advanced gynecologic and genitourinary malignancies. (ucbraid.org)

To date, 5 years after surgery, the patient remains without evidence of tumor recurrence. (mdpi.com)

Our centre managed this case with surgical intervention and patient underwent endoscopic nasopharyngectomy, and planned for right modified radical neck dissection (MRND). (ijorl.com)
Due to the rarity of angiosarcoma in the ovary, this tumor can be a diagnostic challenge to surgical pathologists, particularly during an intraoperative consultation. (hindawi.com)
The surgical margins were tumor free. (klinikitsekoura.gr)
For most tumors, surgical removal is the most effective option. (merckvetmanual.com)
After surgical removal, tumors should be evaluated under a microscope (called a histopathology test) to confirm the type of tumor and whether all of the tumor was likely removed. (merckvetmanual.com)

For all practical purposes in our review we consider carcinosarcomas as only cases where the sarcomatous component was stained negative for epithelial markers, irrespective of the term an author decided to utilize for describing the mixed tumor encountered. (klinikitsekoura.gr)
To include biochemical and/or immunological markers which are specific for a tumour site (Table 2). (who.int)

Antiandrogen withdrawal, for patients having progressive disease while receiving combined hormonal blockade with an LHRH agonist plus an antiandrogen, can provide additional symptomatic relief. (basicmedicalkey.com)
The endocrine dependence of this tumor is well documented, and hormonal manipulation to decrease circulating androgens remains the basis for the treatment of advanced disease. (basicmedicalkey.com)
Hormonal abnormalities and genetic factors may also play a role in the development of skin tumors. (merckvetmanual.com)

Patients (pts) had histologically verified, previously untreated, measurable or evaluable non-resectable NSCLC, without brain metastases and with normal organ functions. (coek.info)
8. One or more tumors measurable on radiographic imaging as defined by RECIST 1.1. (uchicagomedicine.org)

Histology information was not available for 1 patient in the Avastin + PC arm. (avastin.com)
Patient diagnostic information, including histology and survival data, was obtained from the OCR. (ices.on.ca)
The most common metastatic sites were in the respiratory or digestive systems (n = 1,603), and the most common histology was adenocarcinoma (n = 939). (ices.on.ca)
Some subgroups may have better survival rates, such as patients with metastases localised to lymph nodes and patients with squamous cell histology. (ices.on.ca)

It is often used for detecting ascites, biliary or renal obstruction, or pelvic tumors, and is also useful for guiding biopsies. (oncolink.org)

An international system of tumour classification is important for consistency in patient treatments and to provide the basis of epidemiological and biological studies. (ersjournals.com)
[ 1 ] The classification of bile duct tumors has changed to include intrahepatic tumors of the bile ducts and extrahepatic tumors (perihilar and distal) of the bile ducts. (tri-kobe.org)

Surgery is generally not a priority recommendation in such circumstances, except for patients with potentially life-threatening complications such as gastrointestinal bleeding, perforation, or obstruction. (biomedcentral.com)
However, the continuous knowledge which was added by studying these tumors for nearly a century strengthen the notion that the above term was inaccurate or inadequate to describe several parameters of this heterogeneous group of gastrointestinal tumors (including the appendiceal one). (wjgnet.com)
Study design: A total 62 patients with gastrointestinal NHL at the K hospital. (ungthuvn.org)

Nonepithelial malignant neoplasms sometimes arise in mucinous tumors, typically as mural nodules. (hindawi.com)
Most of these tumors arise in the head of the gland. (coek.info)

Their job is to keep abnormal cells from growing and forming tumors. (healthywomen.org)
Tumors are abnormal growths of cells. (merckvetmanual.com)

Anatomy22

Organisms8

Diseases94

Chemicals and Drugs40

Analytical, Diagnostic and Therapeutic Techniques and Equipment55

Phenomena and Processes39

Disciplines and Occupations2

Information Science5

Health Care12

Carcinoma32

Carcinomas4

Diagnosis16

Solid tumors5

Neuroendocrine tumors2

Histologic3

Metastasis5

Poorly4

Lymphoma4

Chemotherapy9

Melanoma3

Cancers4

Epithelial tumors1

Invasive3

Malignant tumor3

Pancreatic7

Breast tumors1

Cancer39

Biopsy8

Benign tumors2

Common tumors1

Primary11

Tissue9

Locally advanced1

Immunohistochemical2

Ductal1

Lung3

Mediastinal3

Osteosarcoma2

Clinical5

Rectal tumor2

Particular tumor1

Prognosis3

Resection1

Gastric adenocarcinoma3

Neoadjuvant1

Ovarian3

Incidence3

Malignancies2

Recurrence1

Surgical5

Markers2

Hormonal3

Measurable2

Histology4

Pelvic1

Classification2

Gastrointestinal3

Arise2

Abnormal2