• The effects of nocodazole, a well established tubulin poison, and JJ78:12 on p53 levels are remarkably similar, supporting that tubulin depolymerization is the main mechanism by which JJ78:12 treatment leads to p53 activation in cells. (biomedsearch.com)
  • Deletion analysis of the flagellar α1-tubulin gene promoter showed that sequences necessary for Li + -induced expression differed from those for acid shock induction and contain a consensus binding site for CREB/ATF and AP-1 transcription factors. (elsevier.com)
  • 2010). Synthesis and Evaluation of Azetidinone Analogues of Combretastatin A-4 as Tubulin Targeting Agents. (cytoskeleton.com)
  • If you are interested in assaying a specific tubulin not listed on our website, please contact our technical support to discuss how we can provide you with the specific tubulin type you want. (cytoskeleton.com)
  • Finally, in silico methods using docking calculations were used to illustrate the binding mode of the new compound to α, -tubulin. (bireme.br)