• The nephron is made of 2 main parts: the renal corpuscle and the renal tubule. (innerbody.com)
  • At the far end of the glomerular capsule, opposite the glomerulus, is the mouth of the renal tubule. (innerbody.com)
  • A series of tubes called the renal tubule concentrate urine and recover non-waste solutes from the urine. (innerbody.com)
  • The renal tubule carries urine from the glomerular capsule to the renal pelvis. (innerbody.com)
  • The curvy first section of the renal tubule is known as the proximal convoluted tubule. (innerbody.com)
  • excretion of drug directly from circulation to intestinal lumen), enteroenteric recirculation (EER), and renal tubule recirculation (RTR) on apixaban pharmacokinetics and disposition. (aspetjournals.org)
  • On the right, you can also see what could be described as normally appearing renal tubule cytoarchitecture, which as you gaze to the left, dissolves into disarray, with a disintegration of the tubular infrastructure. (cdc.gov)
  • ZIP8 is highly expressed in the S3 segment of the proximal tubules of the mouse kidney and may play a significant role in reabsorption of both toxic Cd and essential Mn from the lumen to the epithelial cells of the proximal tubule. (nih.gov)
  • The hOAT3 protein was shown to be localized in the basolateral membrane of renal proximal tubules and the hOAT3 gene was determined to be located on the human chromosome 11q12-q13.3 by fluorescent in situ hybridization analysis. (aspetjournals.org)
  • 10 ] showed that the transplantation of mouse ESCs-derived RPCs can result in the stable integration into proximal tubules with normal morphology and normal polarization injection into developing live newborn mouse kidneys, suggesting the potential of ESCs for application in regenerative therapies. (biomedcentral.com)
  • A typical Sertoli cell tumor (see the images below) is a tumor derived from Sertoli cells, located within seminiferous tubules, which help support spermatogenesis. (medscape.com)
  • The histopathological examination of the gonads revealed atrophy of seminiferous tubule of testis and the epididymis in the two highest dose groups (200 and 800 mg/kg). (europa.eu)
  • We induced high fat diet (HFD) obesity in low-density lipoprotein receptor knock-out Leiden (Ldlr −/− .Leiden) mice, and studied the morphological structure of the testes and histologically examined the proportion of Sertoli cells, spermatocytes and spermatids in the seminiferous tubules. (nature.com)
  • Histology evaluation: Arrest of spermatogenesis during late pachytene stage of meiotic prophase (see 1), some seminiferous tubules have only spermatogonia and Sertoli cells present (see 1), some germ cells appear apoptotic (see 2). (jax.org)
  • Peritubular (intratubular) dentin forms in a regular circular manner on the walls of the dentinal tubules. (tannlegetidende.no)
  • root canal lumen and dentinal tubules are disinfected and dehydrated prior to obturation. (bvsalud.org)
  • B) Magnesium reabsorption in the distal convoluted tubule. (medscape.com)
  • Eventually, all of the tubules will have merged into one main, large tube called the epididymis. (ivf1.com)
  • the epididymis tubules contained no spermatozoa and the deferent duct and vesicular gland were inflamed. (scielo.org.za)
  • this decreases the net negative potential of the tubular lumen and reduces both potassium and hydrogen secretion and their subsequent excretion. (nih.gov)
  • first, organic anions are transported from the peritubular plasma by basolateral organic anion transporter(s) and subsequently effluxed into the tubular lumen by luminal transporter(s). (aspetjournals.org)
  • The driving force for the reabsorption against a concentration gradient is a lumen-positive voltage gradient generated by the reabsorption of NaCl. (medscape.com)
  • Loop diuretics cause increased uric acid reabsorption in the proximal tubule, secondary to hypovolemic states. (pharmacology2000.com)
  • Aldosterone causes the renal tubules to increase the reabsorption of sodium which in consequence causes the reabsorption of water into the blood, while at the same time causing the excretion of potassium (to maintain electrolyte balance). (wikipedia.org)
  • Apical Na+/H+ antiporter and glycolysis-dependent H+-ATPase regulate intracellular pH in the rabbit S3 proximal tubule. (jci.org)
  • The apical transport processes responsible for proton secretion were studied in the isolated perfused rabbit S3 proximal tubule. (jci.org)
  • In conclusion, the S3 proximal tubule has an apical Na+/H+ antiporter with a Michaelis constant for Na+ of 29 mM and a maximum velocity of 0.47 pH/min. (jci.org)
  • Bowman's capsule also has a structural function and creates a urinary space through which filtrate can enter the nephron and pass to the proximal convoluted tubule. (marlerblog.com)
  • Liquid and solutes of the blood must pass through multiple layers to move from the glomerular capillaries into Bowman's space to ultimately become filtrate within the nephron's lumen. (marlerblog.com)
  • We trained the convolutional neural network to segment six major renal structures: glomerular tuft, glomerulus including Bowman's capsule, tubules, arteries, arterial lumina, and veins. (eur.nl)
  • The tubule cells that line the proximal convoluted tubule reabsorb much of the water and nutrients initially filtered into the urine. (innerbody.com)
  • Urine next passes through the loop of Henle, a long straight tubule that carries urine into the renal medulla before making a hairpin turn and returning to the renal cortex. (innerbody.com)
  • Affected reservoir species experience chronic colonization of proximal renal tubules and shed leptospires in urine. (medscape.com)
  • Most mammals can be infected, but rats are considered the main reservoir, maintaining Leptospira spirochetes in the lumen of renal tubules and contaminating the environment with bacteria-infected urine. (cdc.gov)
  • Glomerular filtration rate (GFR), renal plasma flow (RPF), afferent arteriolar resistance (R(A)), efferent arteriolar resistance (R(E)), intraglomerular pressure (P(GLO)), urine albumin-to-creatinine ratio (UACR), and chitinase-3-like protein 1 (YKL-40), a marker of kidney tubule injury, were assessed. (cdc.gov)
  • The semeniferous tubules merge together and will move the sperm toward these larger tubes. (ivf1.com)
  • Histology evaluation: Arrest of spermatogenesis during pachytene stage of meiotic prophase, some tubules are greatly depleted of germ cells (see 1). (jax.org)
  • S3 tubules also possess a plasma membrane H+-ATPase that can regulate pHi, has a requirement for intracellular chloride, and utilizes ATP derived primarily from glycolysis. (jci.org)
  • Portion of a proximal convoluted tubule from a rat kidney with experimental hemoglobinuria. (cellimagelibrary.org)
  • Our results revealed that iPSC-derived RPCs can protect AKI rat from renal function impairment and severe tubular injury by up-regulating the renal tubules formation, promoting cell proliferation, reducing apoptosis, and regulating the microenvironment in the injured kidney. (biomedcentral.com)
  • After a brief exposure to 20 mM NH4Cl, pHi fell by approximately 0.7 and recovered at a rate of 0.89 +/- 0.15 pH/min in the nominal absence of Na+, HCO3-, organic anions, and SO4(2-) (lumen, bath). (jci.org)
  • membrane and were found in the Salamanders, Further pathologic analysis and viral lumen of the renal tubules (online testing were subsequently performed. (cdc.gov)
  • Syzygy and encystment occur in the lumen of the gut (or tubule). (wikipedia.org)
  • These interactions are thus transient and often occur in two directions, from the parenchyma to the lumen and viceversa [ 6 ]. (hindawi.com)
  • Stem cells for sperm are found in the walls of the semeniferous tubules. (ivf1.com)
  • Also Spermatozoon Debris, Reduction In Lumen Size Of Vas Deferens Was Noted. (sersc.org)
  • In a cross-section of the tubules, it has been observed that the outer surface of the cells is covered by muscles and trachea. (tubitak.gov.tr)
  • Tubulointerstitial nephritis is primary injury to renal tubules and interstitium resulting in decreased renal function. (merckmanuals.com)
  • The transplantation of iPSC-derived RPCs decreased the levels of biomarkers indicative of renal injury and attenuated the necrosis and apoptosis of renal tissues, but resulted in the up-regulation of renal tubules formation, cell proliferation, and the expression of pro-renal factors. (biomedcentral.com)
  • You can also see in the lower, middle section, an area of what was described as capillary thrombosis, where thrombi, or blood clots, had occluded the capillary lumina. (cdc.gov)
  • during the final changes of cell division, the nearly mature sperm call is deposited into the lumen of the semeniferous tubule. (ivf1.com)