• Luckins A.G., The immune response of zebu cattle to infection with Trypanosoma congolense and T. vivax , Ann. (gse-journal.org)
  • Out of 22 infected animals 63.64 % cattle were found to be infected by T. congolense , (31.8 %) T. vivax , and (4.55 %) mixed parasites ( T. congolense and T. vivax ).The results showed that, T. congolense was the most prevalent in the study areas and followed by mixed parasites. (symbiosisonlinepublishing.com)
  • For treatment of Trypanosomiasis caused by Trypanosoma vivax, T. congolense, T. brucei, treatment of piroplasmosis caused by Babesia bovis, B. bigemina, B. ovis, B. motasi, B canis, as well as infections caused by Nattalia equi and Theileria annulata. (cphi-online.com)
  • The main species causing AAT in cattle are T. congolense, T. vivax, and T. b. brucei. (kab.ac.ug)
  • These bloodstream forms develop and multiply within the fly and then migrate to the mouthparts ( T. vivax and T. congolense ) or the salivary glands ( T. brucei ). (tsetse.org)
  • This process takes 5-13 days for Trypanosoma vivax , 15-23 days for T. congolense and 12-23 days for T. brucei. (tsetse.org)
  • Infection rates in tsetse populations are generally low, ranging from about 5% for T. vivax and T. congolense to less than 1% for T. brucei. (tsetse.org)
  • From a total of 60 samples that were subjected to PCR 23% (14/60) were T.congolense savannah type positive, 3% (2/60) were T.vivax and 2% (1/60) had mixed infection. (unza.zm)
  • Blood samples were tested for trypanosomes by microscopic observation, species-specific PCR for T . brucei sl, T . congolense , T . vivax and subspecies-specific PCR for T . b . gambiense and T . b . gambiense immune trypanolysis (TL). (researcher-app.com)
  • T. congolense, T. vivax, T. brucei brucei and T. brucei evansi). (123dok.net)
  • Evolution and diagnostic utility of major surface proteases from trypanosoma vivax, t. (ac.ke)
  • N'Dama cattle West African Dwarf goats: 106 West African Dwarf sheep (Djallonké) Cameroon sheep Certain domestic ruminant breeds in sub-saharan Africa show remarkable resistance to the effects of African trypanosomiasis: they can tolerate the parasites's presence while controlling parasitaemia levels and, most importantly, do not show the severe anemia and production loss that are typical of infection in susceptible breeds. (wikipedia.org)
  • Considering the lack of state-of-the-art knowledge on camel trypanosomiasis in Somalia, the present study aimed to assess the prevalence of Trypanosoma spp. (researchgate.net)
  • The existence of an animal reservoir of Trypanosoma brucei gambiense may explain disease persistence in these foci where animal breeding is an important source of income but where the prevalence of animal African trypanosomiasis (AAT) is unknown. (researcher-app.com)
  • Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). (unboundmedicine.com)
  • Here we will apply the knowledge and skills we have gained from our studies of Trypanosoma brucei, which is responsible for human trypanosomiasis, to investigate sexual reproduction in T. congolense, a related livestock pathogen. (ukri.org)
  • Van den Bossche, P & Rowlands, GJ 2001, ' The relationship between the parasitological prevalence of trypanosomal infections in cattle and herd average packed cell volume ', Acta Tropica , vol. 78, no. 2, pp. 163-170. (itg.be)
  • Recent investigations demonstrated that the prevalence of C. sinensis infection remains high in endemic areas. (biomedcentral.com)
  • The results indicate that the prevalence of Sodalis and Trypanosoma varied with country and tsetse species. (bvsalud.org)
  • At each AHF, blood samples from 613 randomly selected cattle were collected to determine trypanosome species prevalence, AAT status and DA resistance in Trypanosoma congolense isolates. (unza.zm)
  • Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection. (univ-amu.fr)
  • mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes. (harvard.edu)
  • Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy. (harvard.edu)
  • Agyemang K., Dwinger R.H., Little D.A., Leperre P., Grieve A.S., Interaction between physiological status in N'Dama cows and trypanosome infections and its effects on health and productivity of cattle in The Gambia, Acta Trop. (gse-journal.org)
  • Trypanosomosis or surra caused by Trypanosoma evansi is a disease of major livestock species and widely distributed in different agro climatic regions of various developing countries including India (Truc et al. (researchsquare.com)
  • Previous studies on detection of Trypanosoma species in Somali camels have only been performed during the 1990s using standard trypanosome detection methods (STDM). (researchgate.net)
  • Sequencing of the ITS1 region of the Trypanosoma species detected herein revealed that camels were infected with T. evansi and T. simiae. (researchgate.net)
  • It showed that co-infections between Wolbachia and S. glossinidius are rare in wild populations of G. m. submorsitans and that the tripartite associations vary according to trypanosome species as well as symbiotic mricroorganisms. (bvsalud.org)
  • Field-caught tsetse flies of ten different taxa and from 15 countries were screened using PCR to detect the presence of Sodalis and Trypanosoma species and analyse their interaction. (bvsalud.org)
  • We determined whether parasitic infections with leeches and/or trypanosomes affected the immune and stress response of an imperiled giant species of amphibian, the eastern hellbender ( Cryptobranchus alleganiensis Daudin). (silverchair.com)
  • T . brucei s.l was the most prevalent trypanosome species (13.7%) followed by T . congolense . (researcher-app.com)
  • From the 46 articles reviewed, a total of 111 plant species were claimed to treat viral infections. (hindawi.com)
  • OBJECTIVES The study was to investigate the effects of Allium sativum extract on Trypanosoma brucei brucei parasites' morphometric parameters, parasitemia and the clinical outcome in white infected Albino laboratory rats in order to determine its trypanocidal effects. (bvsalud.org)
  • Salivarian trypanosomes are extracellular parasites causing anthroponotic and zoonotic infections. (mdpi.com)
  • Molecular diagnosis confirmed the suggests that the isolate is a hybrid parasite, rather presence of Leishmania parasites on the basis of 18S ribo- than the result of a mixed infection ( 7 ). (cdc.gov)
  • The diversity of avian blood parasites is remarkable, and they are often found in co-infections, which is a challenge for wildlife parasitology research. (mdpi.com)
  • 2016). Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice. (ulisboa.pt)
  • Conclusions: Trypanosoma evansi is highly prevalent in camels from the Banadir region of Somalia, particularly in nomadic herds. (researchgate.net)
  • To our knowledge, this is the first study to confirm infections with T. evansi and T. simiae in Somali camels through DNA sequencing. (researchgate.net)
  • (caused by Trypanosoma brucei evansi) has the widest host range and the broadest geographical distribution. (123dok.net)
  • 2000). Infection with T. brucei evansi (hereafter, T. evansi) reduces market value of exported animals, decreases milk yield and lessens animal body condition score, resulting in more than $223 million loss to the camel industry (Salah, Robertson & Mohamed 2015). (123dok.net)
  • Since that time, few studies have been performed on livestock, and most were conducted in a Surra, caused by Trypanosoma evansi, is a re-emerging animal trypanosomosis, which is of special concern for camel-rearing regions of Africa and Asia. (123dok.net)
  • The effect of age, sex and starvation of Glossina morsitans morsitans on the transmission of Trypanosoma congolense and T. congolense/T.B. brucei mixed infections / by Mwangelwa Inambao Mwangelwa. (who.int)
  • Transcriptional profiling of midguts prepared from Trypanosoma/T. congolense-positive Glossina palpalis palpalis collected from two distinct Cameroonian foci : coordinated signatures of the midguts' remodeling as T. congolense-supportive niches. (univ-amu.fr)
  • Clonorchis sinensis infection typically elicits Th1/Th2 mixed immune responses during the course of biliary injury and periductal fibrosis. (biomedcentral.com)
  • These results highlight the role of T. gondii derived redox enzymes as important immune modulators and potentially indicate a role for AAM in modulating immunopathology and promoting parasite replication during T. gondii infection. (biomedcentral.com)
  • Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation. (harvard.edu)
  • Urinary tract infections (UTIs) are one of the major causes of morbidity and comorbidities in patients with underlying conditions, and it accounts for the majority of the reasons for hospital visit globally. (kab.ac.ug)
  • Only a few drugs are available for the treatment of trypanosome infections and therefore, the development of new anti-trypanosomal agents is required. (uea.ac.uk)
  • Additionally T.congolense accounted for the majority trypanosomal infection. (unza.zm)
  • eight (8) of which (Group N) were treated with the A. sativum ethanolic extract on day 5 and day 9 after infection, while the other eight (8)rats (Group Q) received saline treatment on the same days. (bvsalud.org)
  • RESULTS All infected rats became parasitemic two days after infection and reached peak levels on day 4 and 5 post infection. (bvsalud.org)
  • Uninfected saline treated rats maintained normal Hb level (10.6g/L to 11.8g/L) as compared to the uninfected extract treated rats' whose Hb levels was at 13.41g/L to 14.36g/L. The haemoglobin level changed to 8.0g/L four days after the infection in the group N rats before rising to 10.2g/L on day 8 post-infection following the extract treatments. (bvsalud.org)
  • Trypanosome infection did not affect any aspect of hellbender physiology that we measured. (silverchair.com)
  • 0:05) between abnormal PCV and trypanosome infection. (kab.ac.ug)
  • Emerging viral infections are among the major global public health concerns. (hindawi.com)
  • Consequently, reviewing medicinal plants used to treat different viral infections is mandatory. (hindawi.com)
  • The Ethiopian traditional knowledge applies a lot of medicinal plants to treat different viral infections. (hindawi.com)
  • Nowadays, traditional healers from different habitats and geographical locations are showing new candidate combinations for the treatment of viral infections such as SARS-CoV [ 5 ]. (hindawi.com)
  • Latent human infections and possible animal reservoirs may challenge these goals. (unboundmedicine.com)
  • we already know that T. congolense has the genes for these proteins. (ukri.org)
  • Proximity-Dependent Biotinylation and Identification of Flagellar Proteins in Trypanosoma cruzi. (harvard.edu)
  • Frontiers in Cellular and Infection Microbiology. (rug.nl)
  • Investigations on the bacterial fauna and their association with trypanosome infections in tsetse fly have revealed contrasting results. (bvsalud.org)
  • Tsetse flies, vectors of African Trypanosoma, have a highly regulated and defined microbial fauna composed of three bacterial symbionts that may have a role to play in the establishment of Trypanosoma infections in the flies and hence, may influence the vectorial competence of the released sterile males. (bvsalud.org)
  • Sodalis bacteria seem to interact with Trypanosoma infection in tsetse flies. (bvsalud.org)
  • None of the 14 T. congolense isolates showed any genes associated with DA resistance. (unza.zm)
  • Lastly, neutrophil to lymphocyte (N:L) ratios increased in all animals after 24 h of capture and remained elevated for up to 50 h, but these temporal dynamics did not differ with parasite infection. (silverchair.com)
  • Infection with the protozoan parasite T. gondii can occur via the oral route, the foetal-maternal interface, or by consumption of undercooked meat containing parasitic cysts [ 1 ]. (biomedcentral.com)
  • Macrophages sit at the bridge between innate and adaptive immunity and they serve a number of functions, during protozoan infection controlling parasite replication is chief amongst them. (biomedcentral.com)
  • Co-infections not only make parasite morphological and molecular identification difficult, but also might influence the infection dynamics and disease manifestation. (mdpi.com)
  • Antioxidant contents of T. cruzi are a determinant of the parasite survival or death at the moment of the infection [ 10 ]. (biomedcentral.com)
  • We developed all the tools and approaches we need for this project for the related parasite, T. brucei, so it is relatively straightforward to apply these to T. congolense, and our project thus has a high chance of success. (ukri.org)
  • This study revealed that acute inflammatory injury was rapidly triggered by initial infection by C. sinensis juveniles in the host, accompanied by the enrichment of detoxification, inflammation, fibrosis, tumor and metabolism-related pathways in the liver, which provides a new perspective for the early intervention and therapy of clonorchiasis. (biomedcentral.com)
  • The BALB/c mouse model was established to study early infection (within 7 days) with C. sinensis juveniles. (biomedcentral.com)
  • Here we will apply the knowledge and skills gained from our studies of the model organism Trypanosoma brucei to investigate sexual reproduction in T. congolense, a related livestock pathogen of major economic importance to African agriculture. (ukri.org)
  • Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA. (univ-amu.fr)
  • Human Trypanosoma cruzi chronic infection leads to individual level steady-state parasitemia: Implications for drug-trial optimization in Chagas disease. (harvard.edu)
  • We plan to use this system to investigate sexual reproduction in T. congolense in the laboratory. (ukri.org)
  • In addition, the data presented demonstrates the plant extract had the potential to improve the red and white blood cell indices reducing parasitaemia following T. b. brucei infection. (bvsalud.org)
  • Echantillonnage des populations de glossines en secteur guinéen de Côte d' Ivoire : essais de pièges, contribution à la lutte / par Dagnogo Mamadou. (who.int)
  • There is, however, evidence that T. congolense does undergo genetic exchange in natural populations from genetic comparisons of strains collected in Africa. (ukri.org)
  • Human infection zygous SNPs (both haplotypes were different from can result in 2 main forms of disease, cutaneous and M2904) and 104,464 heterozygous SNPs (one haplo- visceral leishmaniasis, and different Leishmania spe- type was similar to M2904 and the other different). (cdc.gov)
  • In this study the effect of 13 iron chelators on the growth of Trypanosoma brucei, T. congolense and human HL-60 cells was tested in vitro. (uea.ac.uk)
  • Proteomic-based GO analysis demonstrated that biological processes such as cell deformation, proliferation, migration and wound healing occurred in the liver during the early infection. (biomedcentral.com)
  • Alternatively activated macrophages (AAM) are a key feature Th2 immunity and have been associated with a variety of roles during helminth infection. (biomedcentral.com)
  • Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth, and lipid homeostasis in Trypanosoma cruzi. (harvard.edu)
  • Blood indicators including ALT, AST, WBC, CRP and IL-6 indicated that both liver injury and systemic inflammation worsened as the infection progressed. (biomedcentral.com)
  • Ovine toxoplasmosis is a major loss to the agricultural industry through foetal loss The outcome of infection for the unborn lamb during pregnancy is dependent on whether infection takes place during early/mid-gestation or late gestation leading to death or live birth, respectively. (biomedcentral.com)
  • We expect to find major differences in the meiotic cells and gametes of T. congolense and T. brucei, based on their known developmental cycles. (ukri.org)
  • This graph shows the total number of publications written about "Trypanosoma cruzi" by people in Harvard Catalyst Profiles by year, and whether "Trypanosoma cruzi" was a major or minor topic of these publication. (harvard.edu)
  • Interfering with iron metabolism may be a new strategy in the treatment of trypanosome infections. (uea.ac.uk)
  • Sodalis glossinidius and Wolbachia infection rates were compared and association studies involving trypanosome infections and S. glossinidius or Wolbachia were performed. (bvsalud.org)
  • The underreporting of infection and death rates represents an unprecedented challenge. (biomedcentral.com)
  • Proteomic data showed that apoptosis and junction-related pathways were enriched within 3 days of infection, indicating the occurrence of liver injury. (biomedcentral.com)