ApoptosisCaspasesCaspase 3DNA FragmentationProto-Oncogene Proteins c-bcl-2In Situ Nick-End Labelingbcl-2-Associated X ProteinSignal TransductionAntigens, CD95PhagocytosisMitochondriaCaspase InhibitorsCells, CulturedCell SurvivalCell Line, TumorCaspase 9Apoptotic Protease-Activating Factor 1Jurkat CellsApoptosis Regulatory ProteinsAnnexin A5NecrosisCell DeathCytochromes cEnzyme ActivationCaspase 8Cell LinePhosphatidylserinesTumor Suppressor Protein p53Fas Ligand ProteinFlow CytometryTumor Cells, Culturedbcl-X ProteinBlotting, WesternCysteine Proteinase InhibitorsMice, Inbred C57BLAmino Acid Chloromethyl KetonesTrigger Finger DisorderPoly(ADP-ribose) PolymerasesProto-Oncogene ProteinsTime FactorsMacrophagesReactive Oxygen SpeciesEnzyme InhibitorsCell ProliferationStaurosporineCaspase 7Mice, KnockoutCytochrome c GroupMembrane Potential, MitochondrialPhosphorylationTrigger PointsCell CycleDNA DamageTransfectionModels, BiologicalCaspase 2Antineoplastic AgentsDose-Response Relationship, DrugCell DivisionCaspase 6HeLa Cellsbcl-2 Homologous Antagonist-Killer ProteinImmunohistochemistryRNA, MessengerMembrane ProteinsBH3 Interacting Domain Death Agonist ProteinRNA, Small InterferingTumor Necrosis Factor-alphaMembrane GlycoproteinsMolecular Sequence DataHL-60 CellsCell NucleusUp-RegulationDown-RegulationProtein BindingMutationGenes, bcl-2NeuronsInhibitor of Apoptosis ProteinsCarrier ProteinsReverse Transcriptase Polymerase Chain ReactionGene Expression RegulationRats, Sprague-DawleyOxidative StressMicroscopy, FluorescenceApoptosis Inducing FactorCaspase 1TNF-Related Apoptosis-Inducing LigandAntineoplastic Agents, PhytogenicCalciumCysteine Endopeptidasesbcl-Associated Death ProteinRNA InterferenceAmino Acid SequenceProtein-Serine-Threonine KinasesPropidiumDisease Models, AnimalMicroscopy, ConfocalNF-kappa BMice, Inbred BALB C