Oxidative StressApoptosisCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesDNA FragmentationMitochondriaAntioxidantsSignal TransductionCell Line, TumorCell SurvivalCaspase 9bcl-2-Associated X ProteinCaspase 8Inhibitor of Apoptosis ProteinsHydrogen PeroxideCells, CulturedFas Ligand ProteinIn Situ Nick-End LabelingCaspase InhibitorsTumor Suppressor Protein p53Enzyme ActivationCell LineCytochromes cTumor Cells, CulturedX-Linked Inhibitor of Apoptosis ProteinBlotting, WesternLipid PeroxidationPoly(ADP-ribose) PolymerasesGlutathioneSuperoxide Dismutasebcl-X ProteinCysteine Proteinase InhibitorsOxidantsCell DeathCASP8 and FADD-Like Apoptosis Regulating ProteinDNA DamageAmino Acid Chloromethyl KetonesFlow CytometryTransfectionMalondialdehydeEnzyme InhibitorsCell ProliferationPhosphorylationProto-Oncogene ProteinsCell CycleJurkat CellsMembrane Potential, MitochondrialTNF-Related Apoptosis-Inducing LigandTime FactorsDown-RegulationApoptosis Inducing FactorUp-RegulationRNA, Small InterferingDose-Response Relationship, DrugCatalaseFas-Associated Death Domain ProteinAntineoplastic AgentsAntigens, CD95Mice, Inbred C57BLRNA, MessengerTumor Necrosis Factor-alphaCytochrome c GroupMembrane GlycoproteinsOxidation-ReductionHeLa CellsThiobarbituric Acid Reactive SubstancesBH3 Interacting Domain Death Agonist ProteinMice, Knockoutbcl-2 Homologous Antagonist-Killer ProteinGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionModels, BiologicalCell DivisionNecrosisProtein CarbonylationReceptors, TNF-Related Apoptosis-Inducing LigandNF-kappa BMutationProtein-Serine-Threonine KinasesCarrier ProteinsProto-Oncogene Proteins c-aktAcetylcysteineRNA InterferenceGlutathione PeroxidaseCell NucleusDNA-Binding ProteinsMyeloid Cell Leukemia Sequence 1 ProteinMembrane ProteinsGene ExpressionFibroblastsTopoisomerase InhibitorsRats, Sprague-DawleyAnnexin A5Mitochondrial MembranesProtein BindingDrug SynergismDisease Models, Animal