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  • acute promyelo
  • Tretinoin is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17) translocation 160 and/or the presence of the PML/RARα gene) and who don't respond to anthracyclines or can't take that class of drug. (wikipedia.org)
  • Tretinoin, a natural vitamin A metabolite, is an anti-cancer drug used in the treatment of acute promyelocytic leukemia (APL). (encyclopedia.com)
  • Tretinoin is used to treat acute promyelocytic leukemia (APL, APML). (chemocare.com)
  • Patients with acute promyelocytic leukemia (APL) are at high risk in general and can have severe adverse reactions to Tretinoin Capsules. (drugs.com)
  • ATRA
  • tretinoin), the acid form of vitamin A. Treatment with ATRA dissociates the NCOR-HDACL complex from RAR and allows DNA transcription and differentiation of the immature leukemic promyelocytes into mature granulocytes by targeting the oncogenic transcription factor and its aberrant action. (wikipedia.org)
  • sunlight
  • Using tretinoin-mequinol with fluoroquinolones, phenothiazines, sulfonamides, or thiazides can increase your skin's sensitivity to sunlight. (webmd.com)
  • Exposure to sunlight, including sunlamps, should be minimized during the use of AVITA® Gel, and patients with sunburn should be advised not to use the product until fully recovered because of heightened susceptibility to sunlight as a result of the use of tretinoin. (rxlist.com)
  • capsules
  • Tretinoin Capsules should therefore be administered only to patients with APL under the strict supervision of a physician who is experienced in the management of patients with acute leukemia and in a facility with laboratory and supportive services sufficient to monitor drug tolerance and protect and maintain a patient compromised by drug toxicity, including respiratory compromise. (drugs.com)
  • Use of Tretinoin Capsules requires that the physician concludes that the possible benefit to the patient outweighs the following known adverse effects of the therapy. (drugs.com)
  • During Tretinoin Capsules treatment about 40% of patients will develop rapidly evolving leukocytosis. (drugs.com)
  • There is a high risk that a severely deformed infant will result if Tretinoin Capsules are administered during pregnancy. (drugs.com)
  • Within 1 week prior to the institution of Tretinoin Capsules therapy, the patient should have blood or urine collected for a serum or urine pregnancy test with a sensitivity of at least 50 mIU/mL. (drugs.com)
  • interact
  • People using the topical form should not also use any cream or lotion that has a strong drying effect, contains alcohol, astringents, spices, lime, sulfur, resorcinol, or aspirin, as these may interact with tretinoin or exacerbate its side effects. (wikipedia.org)
  • patients
  • Tretinoin is given to APL patients with the goal of bringing on a remission. (encyclopedia.com)
  • As many as 60% of patients taking tretinoin develop increased cholesterol and triglyceride levels. (encyclopedia.com)
  • A study done by the Department of Dermato venerology at the Sarajevo University Hospital revealed that tretinoin was effective on acne scars in almost 79 percent of patients. (targetwoman.com)
  • Studies on mequinol and tretinoin have been done only in adult patients, and there is no specific information comparing use of mequinol and tretinoin in children with use in other age groups. (drugs.com)
  • health
  • The amount of tretinoin you will receive depends on many factors, including you height and weight, your general health or other health problems, and the type of cancer you have. (chemocare.com)
  • skin
  • Learn more about using tretinoin creams for acne, wrinkles and skin spots. (targetwoman.com)
  • Tretinoin cream is perhaps the answer to acne breakouts and skin that seems out of control. (targetwoman.com)
  • Dermatologists prescribe tretinoin cream or products with a certain concentration of tretinoin as part of complete anti-aging skin care plan, in addition to controlling acne and reduce fine lines and wrinkles, improve color and tone of the skin and reduce rough patches, not responding to any other types of treatments. (targetwoman.com)
  • Tretinoin cream can be purchased from a dermatologist or a skin medical spa. (targetwoman.com)
  • A pea-sized quantity of tretinoin based cream is applied to the skin after cleansing. (targetwoman.com)
  • This is because, retin A can cause areas of the skin treated with tretinoin to become very sensitive to the sun. (targetwoman.com)
  • Mequinol and Tretinoin is used to treat areas of the skin that have become darker after repeated exposure to the sun. (drugs.com)
  • Do not apply mequinol and tretinoin to windburned or sunburned skin or on open wounds. (drugs.com)
  • turnover
  • Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones. (drugs.com)