• Treponema pallidum, formerly known as Spirochaeta pallida, is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. (wikipedia.org)
  • Three subspecies of T. pallidum are known: Treponema pallidum pallidum, which causes syphilis T. p. endemicum, which causes bejel or endemic syphilis T. p. pertenue, which causes yaws The three subspecies causing yaws, bejel, and syphilis are morphologically and serologically indistinguishable. (wikipedia.org)
  • The FTA-ABS test is used to detect antibodies to the bacteria Treponema pallidum, which causes syphilis . (medlineplus.gov)
  • Without some other evidence for the diagnosis of syphilis, a reactive nontreponemal test does not confirm T. pallidum infection. (cdc.gov)
  • The Serodia TP-PA test is a treponemal test for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema , the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. (cdc.gov)
  • Syphilis is a sexually transmitted disease caused by Treponema pallidum, with human beings as the only host. (medscape.com)
  • Syphilis is caused by infection with the bacterium Treponema pallidum subspecies pallidum . (genetrackdiagnostics.com)
  • Syphilis Syphilis is a sexually transmitted infection caused by the bacteria Treponema pallidum . (msdmanuals.com)
  • Antonio Fornaciari] Syphilis is an infectious disease, sexually transmitted, caused by the bacteria Treponema pallidum . (cdc.gov)
  • There's also another theory--so called an Italian hypotheses--that syphilis is a single organism that is Treponema , caused different clinical manifestations depending upon climatic, social, and demographic factors, producing the clinical manifestation named pinta, yaws, bejel, and syphilis. (cdc.gov)
  • T. pallidum consists of three subspecies, T. p. pallidum, T. p. endemicum, and T. p. pertenue, each of which has a distinct associated disease. (wikipedia.org)
  • T. p. pallidum is the most invasive pathogenic subspecies, while T. carateum is the least invasive of the species. (wikipedia.org)
  • The chromosomes of the T. pallidum subspecies are small, about 1.14 Mbp. (wikipedia.org)
  • Treponema subspecies are cross-reactive ( 6 ). (cdc.gov)
  • Molecular strain typing of the yaws pathogen, Treponema pallidum subspecies pertenue. (cdc.gov)
  • Yaws is a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue. (cdc.gov)
  • Y to perform repeated testing with a preabsorption step to aws is a disease caused by the bacterium Treponema remove all nonspecific binding antibodies (as described in pallidum subsp. (cdc.gov)
  • A sexually transmitted infection caused by the bacterium Treponema pallidum . (aidsmap.com)
  • Treponema pallidum is a helically shaped bacterium with high mobility consisting of an outer membrane, peptidoglycan layer, inner membrane, protoplasmic cylinder, and periplasmic space. (wikipedia.org)
  • The first bacteria sequenced using next-generation technologies included very few that cause sexually transmitted infections (STI) like Chlamydia trachomatis , Treponema pallidum , and Neisseria gonorrhoeae (Ng) . (cdc.gov)
  • It is caused by a bacteria known as Treponema pallidum. (ilgarro.com)
  • Title : Agglutination of Treponema pallidum by reagin antibody Personal Author(s) : McLeod, Charlotte P.;Stokes, Peggie S. (cdc.gov)
  • Although 72 (65%) of 111 serum samples from Guinea were positive for T. pallidum antibodies, none of the samples from Kenya were positive. (cdc.gov)
  • We report serop- TPPA, https://www.fujirebio-us.com), which has been vali- revalence for Treponema pallidum antibodies in olive ba- dated for use in baboons ( 7 ). (cdc.gov)
  • A dilution of the patient's serum is added to the well to allow any T. pallidum -specific antibodies present to bind to the treponemal antigens. (cdc.gov)
  • If the patient has antibodies to T. pallidum , a color reaction takes place. (cdc.gov)
  • BamA apparatus will insert newly synthetised and exported outer membrane proteins into the outer membrane The Treponema repeat family of proteins (Tpr) are proteins expressed during the infection process. (wikipedia.org)
  • Human yaws has historically been endemic to Kenya, but pallidum Particle Agglutination Assay (TPPA) (SERODIA current epidemiologic data are lacking. (cdc.gov)
  • As a result of a renewed focus on the disease owing to a recent eradication effort initiated by the World Health Organization, we have evaluated a typing method, adapted from and based on the enhanced Centers for Disease Control and Prevention typing method for T. pallidum subsp. (cdc.gov)
  • pallidum can be applied to subsp. (cdc.gov)
  • No cases of herpes simplex virus type II or Treponema pallidum were found. (who.int)
  • email: [email protected] dynamics and potential links between human and NHP T. pallidum strains ( 3 ). (cdc.gov)
  • Increased discrimination of Treponema pallidum strains by subtyping with a four-component system incorporating a mononucleotide tandem repeat in rspA. (cdc.gov)
  • Treponema carateum, the cause of pinta, remains a separate species because no isolate is available for DNA analysis. (wikipedia.org)
  • Epidemiology, molecular strain types, and macrolide resistance of Treponema pallidum in Japan, 2017-2018. (bvsalud.org)
  • Molecular typing was performed by analyzing Treponema pallidum arp, tpr, and tp0548 genes , with partial sequencing of the 23S rRNA genes for macrolide resistance. (bvsalud.org)
  • Successful long-term cultivation of T. p. pallidum in a tissue-culture system was reported in 2018. (wikipedia.org)
  • TprK antigen variation can help T. pallidum to evade a strong host immune reaction and can also allow the reinfection of individuals. (wikipedia.org)
  • La VDRL e' un test diagnostico per la sifilide, malattia infettiva contagiosa dovuta ad una spirocheta (Treponema pallidum). (polosanitarioigea.it)
  • In subsequent years, an additional 276 serum samples from baboons in Kenya supported the absence of T. pallidum in- Seroprevalence of fection. (cdc.gov)
  • Human yaws has historically been endemic to Kenya, but pallidum Particle Agglutination Assay (TPPA) (SERODIA current epidemiologic data are lacking. (cdc.gov)
  • However, because this test is not certified for use with NHPs, we subsequently confirmed results by using the T. pallidum Particle Agglutination Assay (TPPA) (SERODIA TPPA, https://www.fujirebio-us.com ), which has been validated for use in baboons ( 7 ). (cdc.gov)
  • In subsequent years, an additional 276 serum samples from baboons in Kenya supported the absence of T. pallidum in- Seroprevalence of fection. (cdc.gov)
  • Diagnosis and test of cure were based on toluidine red unheated serum tests (TRUSTs) and Treponema pallidum hemagglutination assays. (medscape.com)
  • Herein, we demonstrate that the genes encoding the putative TRAP-T components from T. pallidum, tp0957 (the SBP), and tp0958 (the symporter), are in an operon with an uncharacterized third gene, tp0956. (nih.gov)
  • A report from San Francisco in 2001 was the first to associate azithromycin treatment failure with A→G mutations at the 2,058 position of the 23S rRNA gene of T. pallidum . (medscape.com)
  • Treponema pallidum recombinant protein Tp47 enhanced interleukin-6 secretion in human dermal fibroblasts through the toll-like receptor 2 via the p38, PI3K/Akt, and NF-κB signalling pathways. (bvsalud.org)