• Large lesion size (≥109 mm(2)) and the existence of subchondral cysts were significant predictors of unsatisfactory clinical outcomes in group A (P = .04 and .03, respectively). (researchgate.net)
  • Objective: We prospectively evaluated the short-term outcome and the predictors of response to electroconvulsive therapy (ECT) in a large sample of patients with a bipolar mixed state. (psychiatrist.com)
  • This article describes experiences in the community of Göteborg over 20 years with regard to treatment, outcome, and predictors of outcome among patients hospitalised alive after out of hospital cardiac arrest. (bmj.com)
  • However, not all patients experience improvement, and although predictors of treatment outcome have been identified, few are consistent over time and across studies. (frontiersin.org)
  • During the follow up an aggressive treatment strategy was followed in the Dutch and Finnish cohort, an intermediate strategy in the British cohort, and a conservative strategy in the Swedish cohort. (bmj.com)
  • Patients declining randomization will be asked to enroll into an observational cohort with same outcomes and post-treatment regimes. (researchsquare.com)
  • Patients were divided into 2 groups: 35 patients (37 ankles) treated with arthroscopic marrow stimulation treatment alone (group A) and 30 patients (31 ankles) who underwent MSC injection along with arthroscopic marrow stimulation treatment (group B). Clinical outcomes were evaluated according to the visual analog scale (VAS) for pain, the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, and the Roles and Maudsley score. (researchgate.net)
  • In this retrospective review, data from 55 patients with nAMD who underwent ≥6 IVA treatments during the previous 12 months or ≥4 IVA treatments during the previous 6 months were analyzed. (ophthalmology360.com)
  • Primary surgical treatment provides consistent high union rates, but patients are exposed to the risk of complications such as infection, iatrogenic radial nerve lesion and rotator cuff injury as well as shoulder impingement(4,5). (researchsquare.com)
  • The proposed registry would track patients throughout their lives, capturing individual treatment, complications and medicine provided. (spinalcordinjuryzone.com)
  • During the course of the coronavirus disease 2019 (COVID-19) ings, complications, laboratory test results including those pandemic, reports of a new multisystem inflammatory syn- from SARS-CoV-2 testing, imaging findings, treatments, drome in children (MIS-C) have been increasing in Europe and outcomes. (cdc.gov)
  • There is widespread recognition that consistency between research centres in the ways that patients with tinnitus are assessed and outcomes following interventions are measured would facilitate more effective co-operation and more meaningful evaluations and comparisons of outcomes. (nih.gov)
  • METHOD Data from cohorts of patients with early RA, with a standardised assessment at least every six months for five years from four different centres, were included in one database. (bmj.com)
  • The use of rifabutin-containing antituberculosis regimens should always include an assessment of the patient's response to treatment to decide the appropriate duration of therapy (i.e., 6 months or 9 months). (cdc.gov)
  • For these pharmaceuticals, the Horizon Scanning working group writes an early assessment report that describes the current scientific evidence about the treatment and the consequences it may have for the healthcare system. (janusinfo.se)
  • These correlations were not observed in group B. Conclusion: Injection of MSCs with marrow stimulation treatment was encouraging in patients older than 50 years compared with patients treated with marrow stimulation treatment alone, especially when the lesion size was larger than 109 mm(2) or a subchondral cyst existed. (researchgate.net)
  • CONCLUSION This observational study of cohorts of patients with early RA confirms that early aggressive treatment results not only in a more rapid reduction of disease activity but also in less radiographic progression in the long term. (bmj.com)
  • CONCLUSION: PRO indices based only on patient questionnaire data, without joint counts or laboratory tests, may be useful quantitative measures of therapeutic efficacy for use in standard rheumatology clinical care. (jrheum.org)
  • OBJECTIVE To compare four different inception cohorts of patients with early rheumatoid arthritis (RA) with respect to treatment strategies, disease activity, and outcome during a five year follow up period. (bmj.com)
  • An index of patient reported outcomes (PRO-Index) discriminates effectively between active and control treatment in 4 clinical trials of adalimumab in rheumatoid arthritis. (jrheum.org)
  • Methods: Among 107 patients with OLTs treated arthroscopically, only the patients older than 50 years (65 patients) were included in this study. (researchgate.net)
  • METHODS: Data from 4 clinical trials involving adalimumab, in combination with methotrexate or other disease-modifying antirheumatic drugs (DMARD) or as monotherapy, versus control treatment were made available to analyze properties of various indices. (jrheum.org)
  • This has led to research on methods for vaginal and urethral irradiation with lasers, including non-ablative vaginal Erbium:YAG laser treatment (VEL) [ 4 ]. (springer.com)
  • Although he cited us,3 he overlooked the evidence we provided indicating that the Bacloville article4 was published without acknowledging major changes to the initial protocol, affecting the primary outcome. (psychiatrist.com)
  • The primary outcome is the Disability of Arm, Shoulder and Hand (DASH) score at 52 weeks, and is assessor blinded. (researchsquare.com)
  • Patient data were prospectively computerised with regard to factors at resuscitation. (bmj.com)
  • During the 26-week study period patients continued their routine treatment at the clinics. (biomedcentral.com)
  • Therefore they are no longer recommended as routine treatments. (cdc.gov)
  • Although still in the early stages of application, MSCs may have great potential in the treatment of OLTs in patients older than 50 years, and more evaluations of its effect should be performed. (researchgate.net)
  • 1-11 However, an important drawback in applying DMARDs is the high incidence of patients discontinuing treatment because of a lack of efficacy or the occurrence of adverse reactions. (bmj.com)
  • The current study aimed to examine whether treatment self-efficacy (self-efficacy regarding the mastery of obstacles during treatment) in guided Internet-delivered therapy for anxiety disorders in adults could be a predictor of lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Treatment self-efficacy was measured at pre-treatment. (frontiersin.org)
  • The results showed that high treatment self-efficacy was a predictor of both lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Significant interaction effects between time and treatment self-efficacy were found for several of the nine modules that constitutes the treatment program, suggesting that treatment self-efficacy could be a moderator of symptom reduction. (frontiersin.org)
  • The results suggest that measuring treatment self-efficacy may be a valuable tool to identify patients at risk of dropping out, and that treatment self-efficacy could be a predictor and moderator of symptom reduction in guided Internet-delivered therapy. (frontiersin.org)
  • OBJECTIVE: To analyze 2 indices composed of the 3 patient reported outcomes (PRO) in the American College of Rheumatology (ACR) Core Data Set--physical function, pain, and global estimate--without joint count or laboratory data, for capacities to distinguish active from control treatments in 4 pivotal clinical trials. (jrheum.org)
  • These patients might not have positive SARS-CoV-2 PCR or when no abstract was available, the full paper was examined. (cdc.gov)
  • Our outcome for harms is the incidence of serious adverse events associated with each of the treatments. (who.int)
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • In a study of girls with Legg-Calvé-Perthes disease, of the 451 patients who presented at a single large urban children's hospital with a diagnosis of Legg-Calvé-Perthes disease, 82 (18.2%) were female. (medscape.com)
  • These guidelines update previous CDC recommendations for the diagnosis, treatment, and prevention of tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) in the United States. (cdc.gov)
  • Early diagnosis and effective treatment of TB among HIV-infected patients are critical for curing TB, minimizing the negative effects of TB on the course of HIV, and interrupting the transmission of Mycobacterium tuberculosis to other persons in the community. (cdc.gov)
  • A pragmatic randomized controlled trial is planned with two study groups (SHAFT-Y and SHAFT-E). A total of 287 eligible acute humeral shaft fractures are scheduled to be recruited and randomly allocated to surgical or non-surgical treatment with the option of early crossover due to delayed union. (researchsquare.com)
  • What is the relationship between Medicare HMO penetration rates and cost, treatment therapies and treatment outcomes for Medicare fee-for-service patients with acute myocardial infarction (AMI)? (hcfo.org)
  • The first strategy proposed was the pyramid approach, in which the least toxic DMARD, which often seemed to be also the least effective DMARD, was given after a long period of treatment with non-steroidal anti-inflammatory drugs alone. (bmj.com)
  • It goes without saying that evaluation of treatment strategies is far more difficult than (short term) clinical trials comparing single or combination DMARD treatment. (bmj.com)
  • In a short term open randomised controlled trial van der Heide et al concluded that suppression of disease activity was much better after immediate introduction of DMARD treatment. (bmj.com)
  • How do the remaining treatments compare with placebo in achieving long-term abstinence? (who.int)
  • Our outcome for benefit is continuous or prolonged abstinence at least six months from the start of treatment. (who.int)
  • Alcohol-dependent patients who are co-morbid for major depressive disorder (MDD) constitute a patient group whose pharmaceutical treatment has been particularly difficult [ 3 ]. (biomedcentral.com)
  • Horizon scanning involves collecting and evaluating information about new pharmaceutical treatments before they are approved for marketing authorisation. (janusinfo.se)
  • 3) severe dysfunction of one or more nine patients reported to CDC, seven from published case extrapulmonary organ systems (e.g., hypotension or shock, reports, and summarizes the findings in 11 patients described cardiac dysfunction, arterial or venous thrombosis or throm- in three case series in peer-reviewed journals ( 4-6 ). (cdc.gov)
  • and 5) absence of severe respiratory illness (to concurrently received positive test results for SARS-CoV-2, exclude patients in which inflammation and organ dysfunc- the virus that causes COVID-19, by polymerase chain reaction tion might be attributable simply to tissue hypoxia). (cdc.gov)
  • Both surgical and non-surgical treatment can have disabling consequences such as nerve injury, infection and nonunion. (researchsquare.com)
  • Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa. (medscimonit.com)
  • Adding to CDC's current recommendations for administering isoniazid preventive therapy to HIV-infected persons with positive tuberculin skin tests and to HIV-infected persons who were exposed to patients with infectious TB, this report also describes in detail the use of new short-course (i.e., 2 months) multidrug regimens (e.g., a rifamycin, such as rifampin or rifabutin, combined with pyrazinamide) to prevent TB in persons with HIV infection. (cdc.gov)
  • It should be noted that despite additional treatments, patients treated with endovascular treatment continued have lower rates of death and disability than those treated with open surgery. (scienceblog.com)
  • Method: From January 2006 to May 2011, we performed an analysis using data obtained from 197 of 203 consecutive patients with a bipolar mixed state, according to DSM-IV-TR diagnostic criteria, who were treated with ECT at the Department of Psychiatry of the University of Pisa. (psychiatrist.com)
  • Dr Kanna Jayaprakasan, Associate Professor in Reproductive Medicine, University of Nottingham and Consultant subspecialist, Derby Fertility Unit, Royal Derby Hospital, senior author of the paper said: "The data suggests that ethnicity is a major independent factor determining the chances of IVF or ICSI treatment success. (nottingham.ac.uk)
  • This interesting study looking at maternal ethnicity provides useful data based on a large number of women undergoing fertility treatment. (nottingham.ac.uk)
  • Advocates believe more data could save the health system millions of dollars and improve the outcomes of people living with spinal cord injury (SCI). (spinalcordinjuryzone.com)
  • You actually need to generate data on hundreds of patients. (spinalcordinjuryzone.com)
  • Data from patients aged 35-50 years who were treated for SUI and registered at several institutions were selected. (springer.com)
  • The analyzed data comes from an open effectiveness study including 575 patients receiving guided Internet-delivered therapy for panic disorder or social anxiety disorder. (frontiersin.org)
  • RESULTS: All indices distinguished active versus control treatment at similar levels, including PRO-Index M versus ACR20, ACR50, and ACR70 responses, and PRO-Index C versus DAS28. (jrheum.org)
  • The results in the treatment with selective serotonin re-uptake inhibitors have been conflicting. (biomedcentral.com)
  • Our results indicate that both memantine and escitalopram are useful adjunct medications for the treatment of alcohol dependence co-morbid with major depression. (biomedcentral.com)
  • MAIN RESULTS: We identified 12 treatment-specific reviews. (who.int)
  • While minimally invasive coil treatments for those with a ruptured brain aneurysm have proved to be a more effective technique than traditional surgical operation in selected patients, the superior procedure is drastically more expensive, according to new research from the Zeenat Qureshi Stroke Research Center at University of Minnesota Medical School. (scienceblog.com)
  • If nonunion occurs, it is not uncommon for patients to go through a prolonged treatment course up to 8 months before an additional procedure is offered(10,11). (researchsquare.com)
  • The most notable changes in these guidelines reflect both the recent advances in the use of antiretroviral therapy and the findings of clinical trials that evaluated new drug regimens for the treatment and prevention of TB among HIV-infected persons. (cdc.gov)
  • In contrast, union rates from non-surgical treatment can vary from 75-100%(6-10). (researchsquare.com)
  • and is the largest to date to look at individual sub-ethnic groups as an independent factor on the success rates of fertility treatment. (nottingham.ac.uk)
  • Dr Patrick Chien, Consultant in Obstetrics & Gynaecology and Deputy Editor in Chief of BJOG said: "This study will be helpful for future treatment and could aid tailored treatment for women to maximise success rates. (nottingham.ac.uk)
  • To describe the change in survival and factors associated with survival during a 20 year period among patients suffering from out of hospital cardiac arrest and being hospitalised alive. (bmj.com)
  • All patients hospitalised alive in the community of Göteborg after out of hospital cardiac arrest between 1 October 1980 and 1 October 2000 were included. (bmj.com)
  • 5505 patients suffered from cardiac arrest during the time of the survey. (bmj.com)
  • Major indicators for a lower chance were high age, requirement for atropine in the emergency department, and chronic treatment with diuretics before cardiac arrest. (bmj.com)
  • Our hypothesis was that among patients hospitalised alive after out of hospital cardiac arrest there would be an increase in survival to discharge over time and that factors associated with survival can be defined from history, factors at resuscitation, and status on admission to the emergency department. (bmj.com)
  • With accrual of additional years with better outcome status, the cost-effectiveness of endovascular coiling would most likely progressively improve and eventually reverse direction, said Alberto Maud, M.D., principal investigator of the study. (scienceblog.com)
  • 1993) Although one might conclude that charcoal and gastric emptying might improve outcome for these cases. (cdc.gov)
  • Evidence is lacking to demonstrate that syrup of ipecac, activated charcoal, and cathartics improve outcome in poisoning. (cdc.gov)
  • The average age of patients ranged from 29.7 years to 35.8 years. (nottingham.ac.uk)
  • The objective of the project was to examine the relationships between Medicare managed care penetration and other market factors, and how managed care affects treatment patterns of Medicare patients who are not enrolled in managed care. (hcfo.org)
  • A significant improvement in disease activity was seen in all cohorts, though the most rapid and striking improvement was seen in those receiving aggressive treatment. (bmj.com)
  • Three of nine modules in the panic disorder treatment and six of nine in the social anxiety disorder treatment showed significant interaction effects. (frontiersin.org)
  • SHAFT will provide information on the effectiveness of two standard treatments for humeral shaft fractures, while taking the dilemmas within the population into account. (researchsquare.com)
  • partly because multiple follow-up treatments are necessary within the first year of endovascular treatments, as opposed to one major surgical operation. (scienceblog.com)
  • The outcome of non-surgical treatment is generally good, but the treatment course can be long and painful with approximately a quarter of the patients acquiring a nonunion. (researchsquare.com)
  • The purpose of the study is to compare patient reported outcome after surgical and non-surgical treatment for humeral shaft fractures. (researchsquare.com)
  • One of the main challenges with humeral shaft fractures is the choice between surgical and non-surgical treatment(3). (researchsquare.com)
  • To our knowledge, three randomized controlled trials (RCT) have been completed and all trials compared plate osteosynthesis to non-surgical treatment without distinction of age(11,16,17). (researchsquare.com)
  • Two RCTs are comparing plate osteosynthesis to non-surgical treatment and the last two RCTs are comparing plate and nails to non-surgical treatment. (researchsquare.com)
  • The patients attended visits weekly during the first month, and then at 3 and at 6 months. (biomedcentral.com)
  • There were 28 patients who switched from IVA to IVF who received 3 treatments within 4 months and 27 patients who remained on IVA and received 3 treatments within 4 months. (ophthalmology360.com)
  • Patients were divided into two groups (the first and second 10 year periods). (bmj.com)
  • The authors cautioned that studies with longer follow-up periods are needed to determine if the outcomes can be maintained. (ophthalmology360.com)
  • Spinal cord injury experts in Australia have lobbied the Federal Government to establish a national register tracking the treatment and condition of patients. (spinalcordinjuryzone.com)
  • In the present study, we retrospectively extracted TVT and VEL cases from the Japanese medical records to establish a database containing all SUI procedures and outcomes. (springer.com)
  • At the first Tinnitus Research Initiative meeting held in Regensburg in July 2006 an attempt was made through workshops to gain a consensus both for patient assessments and for outcome measurements. (nih.gov)
  • This study complemented a similar HCFO project being investigated by researchers at Stanford University on health outcomes for cancer patients. (hcfo.org)
  • The secondary outcomes are DASH score, EQ-5D-5L, pain assessed by visual analogue score, Constant-Murley score including elbow range of motion and anchor-questions collected at all timepoints throughout the trial. (researchsquare.com)
  • The Tegner activity scale was used to determine outcomes in activity levels. (researchgate.net)
  • The completion rate was high in both groups, especially among the patients who had been abstinent at the beginning of the study. (biomedcentral.com)
  • Early age at first alcohol intoxication predicted poor treatment outcomes in patients treated with escitalopram, and the same was seen with the early onset of the first depressive episode. (biomedcentral.com)
  • Persistent levels of cholinesterase inhibitors have been detected in the gastric contents of some patients suffering from the intermediate syndrome (a delayed manifestation of cholinesterase inhibitor poisoning - discussed later). (cdc.gov)
  • Professor Adam Balen, spokesperson for the Royal College of Obstetricians and Gynaecologists (RCOG) and Chair of the British Fertility Society (BFS) said: "Infertility affects 10-15% of the population and more people are seeking fertility treatment. (nottingham.ac.uk)
  • A large proportion of patients who die from ischaemic heart disease die outside hospital in sudden death. (bmj.com)
  • All HIV-infected patients undergoing treatment for TB should be evaluated for antiretroviral therapy, because most patients with HIV-related TB are candidates for concurrent administration of antituberculosis and antiretroviral drug therapies. (cdc.gov)
  • Ideally, the management of TB among HIV-infected patients taking antiretroviral drugs requires a) directly observed therapy, b) availability of experienced and coordinated TB/HIV care givers, and in most situations, c) use of a TB treatment regimen that includes rifabutin instead of rifampin. (cdc.gov)
  • Because alternatives to the use of rifampin for antituberculosis treatment are now available, the previously recommended practice of stopping protease inhibitor therapy to allow the use of rifampin for TB treatment is no longer recommended for patients with HIV-related TB. (cdc.gov)
  • Physicians and patients also should be aware that paradoxical reactions might occur during the course of TB treatment when antiretroviral therapy restores immune function. (cdc.gov)
  • The ethnicity of women undergoing fertility treatments like IVF can affect the rate of successful live births, according to new research by experts at The University of Nottingham and the Royal Derby Hospital's Fertility Unit . (nottingham.ac.uk)
  • How do the risks of adverse and serious adverse events (SAEs) compare between the treatments, and are there instances where the harms may outweigh the benefits? (who.int)
  • The study found that certain ethnic groups have significantly lower chances of live births using fertility treatments than other groups. (nottingham.ac.uk)
  • The paper explores the possible reasons behind the variation and states that while genetic background could be a potential determinant of egg and sperm quality, variation in environmental exposures relating to lifestyle, dietary factors, socio-economic and cultural factors could be influencing egg and sperm quality, accessibility of fertility treatment and behaviour towards seeking medical care and consequently reproductive outcomes. (nottingham.ac.uk)
  • Patients with medical records covering 1 year for the 1-h pad test, who completed the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and the Overactive Bladder Symptom Score (OABSS), were included. (springer.com)
  • Thus, we compared in alcohol-dependent patients with co-morbid major depressive disorder the selective serotonin re-uptake inhibitor escitalopram to a compound that acts on different transporter system and may reduce craving, the glutamate receptor antagonist memantine. (biomedcentral.com)
  • Eighty alcohol-dependent patients comorbid with major depressive disorder in municipal alcohol clinics were randomized 1:1 to receive memantine 20 mg or escitalopram 20 mg in a double-blind manner. (biomedcentral.com)
  • Major indicators for an increased chance of survival were initial ventricular fibrillation/tachycardia, bystander cardiopulmonary resuscitation, arrest being witnessed, and the patient being conscious on admission. (bmj.com)
  • We retrospectively compared tension-free vaginal tape (TVT) and non-ablative vaginal Erbium:YAG laser treatment (VEL) by propensity score (PS) analysis in women with SUI. (springer.com)
  • The study analysed fertility outcomes such as number of eggs retrieved, number fertilised, number of embryos created, implantation rate and live birth rate, which was the main outcome measure in the study. (nottingham.ac.uk)
  • After adjusting for certain factors including age of patient at time of treatment, cause of female or male infertility, and type of treatment (ICSI vs IVF), the study found that White Irish, South Asian Indian, South Asian Bangladeshi, South Asian Pakistani, Black African, and Other Asian women had a significantly lower odds of a live birth than White British women. (nottingham.ac.uk)
  • Considering this demographic difference, the importance of age in terms of patient expectations, upper limb function and patient-reported outcome measures (PROM) in humeral shaft fracture treatment is not well understood. (researchsquare.com)
  • Outcome measures were Alcohol Use Disorders Identification Test (AUDIT), Obsessive Compulsive Drinking Scale (OCDS) and Drinking Diary. (biomedcentral.com)
  • Currently about 30 to 40 percent of all patients with aneurysms are treated with minimally invasive procedures, he said. (scienceblog.com)
  • Purpose: To compare the clinical outcomes of MSC injection and arthroscopic marrow stimulation treatment with those of arthroscopic marrow stimulation treatment alone for the treatment of OLTs in older patients. (researchgate.net)
  • A Retrospective Study to Compare Pharyngeal Anatomical Changes Measured Before and After Treatment for Malo. (medscimonit.com)